Calycopteris floribunda
Species
KNApSAcK Entry
| Organism name | Calycopteris floribunda |
|---|---|
| Genus | Calycopteris |
| Family | Combretaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Calycopteris floribunda |
|---|---|
| Linked NCBI taxonomy ID | 134915 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Combretaceae |
|---|---|
| ID | 3954 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (17)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005374
|
Quercetin
|
CHEMBL82242
CHEMBL479232 CHEMBL1437696 |
C012526
|
14 / 2 / 2 | 2 / 1 | No. 2 | No. 15 |
|
|
C00004673
|
5-Hydroxyauranetin
/ 5-Hydroxy-3,6,7,8,4'-pentamethoxyflavone / 5-Hydroxy-3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one |
CHEMBL504047
|
No. 8 | No. 15 |
|
|||
|
C00004670
|
Calycopterin
/ 5,4'-Dihydroxy-3,6,7,8-tetramethoxyflavone / 5-Hydroxy-2-(4-hydroxyphenyl)-3,6,7,8-tetramethoxy-4H-1-benzopyran-4-one |
CHEMBL512767
|
No. 8 | No. 15 |
|
|||
|
C00004799
|
3'-Methoxycalycopterin
/ 5,4'-Dihydroxy-3,6,7,8,3'-pentamethoxyflavone / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7,8-tetramethoxy-4H-1-benzopyran-4-one |
CHEMBL59220
|
C094781
|
15 / 7 / 2 | No. 8 | No. 15 |
|
|
|
C00013565
|
Isocalycopterone
/ (2R,7aS,11R,13S,14aR)-rel-(-)-2,3,12,13-Tetrahydro-9-hydroxy-6,7,7a,8,13-pentamethoxy-2,11-diphenyl-11H-furo[2,3-f:4,5-i']bis[1]benzopyran-5(7aH)-one |
No. 716 |
|
|||||
|
C00013560
|
4-Hydroxycalycopterone
/ 4-Demethylcalycopterone |
CHEMBL34536
|
No. 716 |
|
||||
|
C00013563
|
Calycopterone
/ (2R,7aS,11R,13S,14aR)-rel-(-)-2,3,12,13-Tetrahydro-8-hydroxy-6,7,7a,9,13-pentamethoxy-2,11-diphenyl-11H-furo[2,3-f:4,5-i']bis[1]benzopyran-5(7aH)-one |
CHEMBL34316
|
C087209
|
No. 716 |
|
|||
|
C00014751
|
6-epi-Calyflorenone C
/ (2S,4R,6R,6aR,8R,10S,13bR)-2,3,4,6,6a,9,10,13b-Octahydro-4,8-dihydroxy-6,6a,12,13,13b-pentamethoxy-2,10-diphenyl-, 5H,8H-furo[2,3-f:5,4-h']bis[1]benzopyran-5-one |
No. 716 |
|
|||||
|
C00014750
|
6-epi-Calyflorenone B
/ (2S,4R,6R,6aR,8R,10S,13bR)-2,3,4,6,6a,9,10,13b-Octahydro-8-hydroxy-4,6,6a,12,13,13b-hexamethoxy-2,10-diphenyl-5H,8H-furo[2,3-f:5,4-h']bis[1]benzopyran-5-one |
CHEMBL1685074
|
2 / 3 / 0 | No. 716 |
|
|||
|
C00014744
|
Neocalycopterone methyl ether
/ (2R,7aR,11R,13S,14aR)-2,3,12,13-Tetrahydro-6,7,7a,8,9,13-hexamethoxy-2,11-diphenyl-11H-furo[2,3-f:4,5-i']bis[1]benzopyran-5(7aH)-one |
CHEMBL284830
CHEMBL1685073 |
2 / 3 / 0 | No. 716 |
|
|||
|
C00014745
|
Calyflorenone A
/ (2S,4R,6S,6aR,8R,10S,13bR)-2,3,4,6,6a,9,10,13b-octahydro-4,6,6a,8,12,13,13b-Heptamethoxy-2,10-diphenyl-5H,8H-furo[2,3-f:5,4-h']bis[1]benzopyran-5-one |
No. 716 |
|
|||||
|
C00014746
|
Calyflorenone B
/ (2S,4R,6S,6aR,8R,10S,13bR)-2,3,4,6,6a,9,10,13b-Octahydro-8-hydroxy-4,6,6a,12,13,13b-hexamethoxy-2,10-diphenyl-5H,8H-furo[2,3-f:5,4-h']bis[1]benzopyran-5-one |
CHEMBL1685074
|
2 / 3 / 0 | No. 716 |
|
|||
|
C00014747
|
6''-Demethoxyneocalycopterone
|
No. 716 |
|
|||||
|
C00014748
|
Calyflorenone D
/ (2S,4R,6aR,8R,10S,13bR)-2,3,4,6,6a,9,10,13b-Octahydro-4,8-dihydroxy-6a,12,13,13b-tetramethoxy-2,10-diphenyl-5H,8H-furo[2,3-f:5,4-h']bis[1]benzopyran-5-one |
No. 716 |
|
|||||
|
C00014749
|
Calyflorenone C
/ (2S,4R,6S,6aR,8R,10S,13bR)-2,3,4,6,6a,9,10,13b-Octahydro-4,8-dihydroxy-6,6a,12,13,13b-pentamethoxy-2,10-diphenyl-5H,8H-furo[2,3-f:5,4-h']bis[1]benzopyran-5-one |
No. 716 |
|
|||||
|
C00014743
|
Neocalycopterone
/ (2R,7aR,11R,13S,14aR)-2,3,12,13-Tetrahydro-13-hydroxy-6,7,7a,8,9-pentamethoxy-2,11-diphenyl-11H-furo[2,3-f:4,5-i']bis[1]benzopyran-5(7aH)-one |
CHEMBL1685072
|
2 / 3 / 0 | No. 716 |
|
|||
|
C00003136
|
Gossypol
|
CHEMBL51483
|
D006072
|
78 / 69 / 87 | 17 / 2 | No. 4111 | No. 39 |
|
Human Protein / Gene in interactions
101 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08183 | Multidrug resistance protein 1 | drug | C00014743 C00014744 C00014746 C00014750 | 1 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00014743 C00014744 C00014746 C00014750 | 2 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003136 C00005374 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00003136 C00005374 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00003136 C00005374 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00003136 C00005374 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00003136 C00005374 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00003136 C00005374 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00003136 C00005374 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003136 C00005374 | 0 / 0 |
| P10415 | Apoptosis regulator Bcl-2 | Other cytosolic protein | C00003136 | 0 / 7 |
| P06746 | DNA polymerase beta | Enzyme | C00003136 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00003136 | 1 / 1 |
| P29466 | Caspase-1 | C14 | C00003136 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00003136 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00003136 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003136 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00003136 | 11 / 10 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003136 | 4 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00005374 | 1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003136 | 3 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00003136 | 0 / 0 |
| P02768 | Serum albumin | Secreted protein | C00003136 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003136 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003136 | 0 / 1 |
| Q92843 | Bcl-2-like protein 2 | Other cytosolic protein | C00003136 | 0 / 0 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005374 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00003136 | 1 / 2 |
| P51570 | Galactokinase | Enzyme | C00003136 | 1 / 1 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00003136 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003136 | 2 / 3 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00003136 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003136 | 2 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00003136 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00003136 | 1 / 1 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003136 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00003136 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003136 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00003136 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00003136 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00003136 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00005374 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005374 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003136 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00003136 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003136 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00003136 | 0 / 1 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00003136 | 5 / 3 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00003136 | 2 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00003136 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00003136 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003136 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00003136 | 3 / 3 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00003136 | 4 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00003136 | 2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003136 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003136 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00003136 | 1 / 1 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003136 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003136 | 0 / 0 |
| P55210 | Caspase-7 | C14 | C00003136 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003136 | 1 / 1 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00003136 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003136 | 0 / 1 |
| P52732 | Kinesin-like protein KIF11 | Other cytosolic protein | C00003136 | 1 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00003136 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00003136 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00005374 | 0 / 0 |
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00005374 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003136 | 4 / 3 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00003136 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003136 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00003136 | 3 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003136 | 0 / 0 |
| Q07817 | Bcl-2-like protein 1 | Other cytosolic protein | C00003136 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00003136 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00003136 | 7 / 37 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00003136 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00003136 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00003136 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003136 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00003136 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003136 | 1 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00003136 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00003136 | 1 / 4 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00004799 | 0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00004799 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00004799 | 1 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00004799 | 2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00004799 | 0 / 0 |
| P07437 | Tubulin beta chain | Structural | C00004799 | 0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00004799 | 1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00004799 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00004799 | 2 / 1 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00003136 | 0 / 0 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00004799 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00004799 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00004799 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00004799 | 0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00004799 | 0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00004799 | 1 / 0 |
19 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00005374
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00005374
|
| 27113 | BBC3, JFY-1, JFY1, PUMA | BCL2 binding component 3 |
C00003136
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00003136
|
| 10018 | BCL2L11, BAM, BIM, BOD | BCL2-like 11 (apoptosis facilitator) |
C00003136
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00003136
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00003136
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00003136
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00003136
|
| 2919 | CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
C00003136
|
| 2050 | EPHB4, HTK, MYK1, TYRO11 | EPH receptor B4 (EC:2.7.10.1) |
C00003136
|
| 2247 | FGF2, BFGF, FGF-2, FGFB, HBGF-2 | fibroblast growth factor 2 (basic) |
C00003136
|
| 2261 | FGFR3, ACH, CD333, CEK2, HSFGFR3EX, JTK4 | fibroblast growth factor receptor 3 (EC:2.7.10.1) |
C00003136
|
| 3397 | ID1, ID, bHLHb24 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
C00003136
|
| 3911 | LAMA5 | laminin, alpha 5 |
C00003136
|
| 4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00003136
|
| 4192 | MDK, ARAP, MK, NEGF2 | midkine (neurite growth-promoting factor 2) |
C00003136
|
| 5154 | PDGFA, PDGF-A, PDGF1 | platelet-derived growth factor alpha polypeptide |
C00003136
|
| 1890 | TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF | thymidine phosphorylase (EC:2.4.2.4) |
C00003136
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (81)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| %606641 | Body mass index; bmi |
P37231
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 |
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #230200 | Galactokinase deficiency |
P51570
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #152950 | Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation; mclmr |
P52732
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P37231
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (91)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
P10415 (related) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
P10415 (related) |
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
P10415 (related) |
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
P10415 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
P10415 (related) |
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00030 | Cervical cancer |
P10415
(related)
|
| H00054 | Nasopharyngeal cancer |
P10415
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00070 | Galactosemia |
P51570
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|