Species

KNApSAcK Entry

Organism name Tagetes elliptica
Genus Tagetes
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tagetes
Linked NCBI taxonomy ID 13707
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005548 External link 512 Narcissin
/ Isorhamnetin 3-O-rutinoside
CHEMBL84174
CHEMBL258394
CHEMBL1711509
CHEMBL2165403
C031062
7 / 1 / 2 No. 1 No. 15
C00005401 External link 512 Quercetin 3-robinoside
/ Quercetin 3-O-robinoside
/ Quercetin 3-O-robinobioside
/ Quercetin 3-O-rhamnosyl-(1->6)-galactoside
CHEMBL32579
CHEMBL310754
CHEMBL182108
CHEMBL226335
CHEMBL502782
CHEMBL1436093
CHEMBL1532989
25 / 18 / 16 No. 1 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00005729 External link 512 Myricetin 3-glucoside
/ Myricetin 3-O-beta-D-glucoside
/ Myricetin 3-O-beta-D-glucopyranoside
CHEMBL462244
CHEMBL1221722
No. 2 No. 15
C00005951 External link 512 Quercetin 3-(6''-galloylgalactoside)
CHEMBL499432
No. 98
C00005953 External link 512 Quercetin 3-(3'',6''-diacetylgalactoside)
No. 330
C00005954 External link 512 Quercetin 3-(2'',3'',4''-triacetylgalactoside)
No. 330

Human Protein / Gene in interactions

38 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005374 C00005401 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005374 C00005401 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005374 C00005401 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005374 C00005401 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005374 C00005548 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005401 C00005548 0 / 1
P03372 Estrogen receptor NR3A1 C00005401 C00005548 1 / 1
P07237 Protein disulfide-isomerase Enzyme C00005374 C00005548 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00005401 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00005401 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00005374 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005374 0 / 0
O75496 Geminin Unclassified protein C00005548 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00005401 0 / 0
P15121 Aldose reductase Enzyme C00005374 0 / 0
P27487 Dipeptidyl peptidase 4 S9B C00005401 0 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00005548 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005374 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005374 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005401 1 / 0
P14679 Tyrosinase Oxidoreductase C00005401 4 / 2
P06276 Cholinesterase Hydrolase C00005401 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00005401 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00005401 3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00005401 2 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005548 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00005401 0 / 0
P22303 Acetylcholinesterase Hydrolase C00005401 1 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00005401 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005401 1 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00005374 0 / 0
P06746 DNA polymerase beta Enzyme C00005401 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00005401 4 / 3
P48147 Prolyl endopeptidase S9A C00005401 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00005401 0 / 3
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00005401 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005374 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00005374
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00005374

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#614490 Blood group, junior system; jr Q9UNQ0
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (17)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00032 Thyroid cancer P27487 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D010146 Pain C00005374