PCIDB

Riella affinis

Species

KNApSAcK Entry

Organism name Riella affinis
Genus
Family
Kingdom

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00001017 External link 512 Cosmosiin
/ Apigenin 7-glucoside
/ (-)-Apigenin 7-glucoside
/ Apigenin 7-O-beta-D-glucopyranoside
CHEMBL487995
CHEMBL487017
CHEMBL1591566
CHEMBL2165585
C057792
5 / 6 / 1 No. 2 No. 15
C00001029 External link 512 Chrysoeriol
/ Luteolin 3'-methyl ether
CHEMBL214321
C007054
20 / 24 / 20 8 / 0 No. 3 No. 15

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs C00001029 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001017 4 / 1
P06746 DNA polymerase beta Enzyme C00001029 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00001029 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001029 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001029 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001029 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001029 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001029 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001029 2 / 0
O75496 Geminin Unclassified protein C00001029 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00001029 4 / 2
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001029 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00001017 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001017 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00001029 5 / 3
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001029 4 / 4
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001029 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001017 2 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001029 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001029 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001029 4 / 3
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00001029 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001017 0 / 0
O00255 Menin Unclassified protein C00001029 2 / 5

8 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001029
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001029
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001029
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001029
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001029
4543 MTNR1A, MEL-1A-R, MT1 melatonin receptor 1A C00001029
4544 MTNR1B, FGQTL2, MEL-1B-R, MT2 melatonin receptor 1B C00001029
4835 NQO2, DHQV, DIA6, NMOR2, QR2 NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2) C00001029

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (30)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
%606641 Body mass index; bmi P37231
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P84022
#237500 Dubin-johnson syndrome; djs Q92887
#600274 Frontotemporal dementia; ftd P10636
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#601665 Obesity P37231
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260540 Parkinson-dementia syndrome P10636
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (21)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00208 Hyperbilirubinemia Q92887 (related)