| Organism name | Salvia albimaculata | 
|---|---|
| Genus | Salvia | 
| Family | Labiatae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Salvia | 
|---|---|
| Linked NCBI taxonomy ID | 21880 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Lamiaceae | 
|---|---|
| ID | 4136 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | 
                        # of proteins in
                         ChEMBL interaction / related OMIM / related KEGG DISEASE  | 
                      
                        # of genes in
                         CTD interaction / related diseases  | 
                      
                        KCF-S
                         cluster  | 
                      
                        phytochemical
                         cluster  | 
                      figure | 
|---|---|---|---|---|---|---|---|---|
| 
                        C00001017
                        
                           | 
                      
                        Cosmosiin
                         / Apigenin 7-glucoside / (-)-Apigenin 7-glucoside / Apigenin 7-O-beta-D-glucopyranoside  | 
                      
                        CHEMBL487995
                         CHEMBL487017 CHEMBL1591566 CHEMBL2165585  | 
                      
                        C057792
                         | 
                      5 / 6 / 1 | No. 2 | No. 15 | 
                         
                       | 
                    |
| 
                        C00000674
                        
                           | 
                      
                        Luteolin
                         | 
                      
                        CHEMBL151
                         | 
                      
                        D047311
                         | 
                      99 / 91 / 95 | 76 / 6 | No. 71 | No. 15 | 
                         
                       | 
                    
| 
                        C00003817
                        
                           | 
                      
                        Apigenin
                         / 5,7,4'-Trihydroxyflavone  | 
                      
                        CHEMBL28
                         | 
                      
                        D047310
                         | 
                      164 / 119 / 105 | 68 / 8 | No. 71 | No. 15 | 
                         
                       | 
                    
| 
                        C00002724
                        
                           | 
                      
                        Heriguard
                         / Chlorogenic acid / 3-O-Caffeoylquinic acid  | 
                      
                        CHEMBL284616
                         CHEMBL230481 CHEMBL249450 CHEMBL1332980 CHEMBL1394423 CHEMBL1419611 CHEMBL1473644 CHEMBL1552319  | 
                      
                        D002726
                         | 
                      30 / 19 / 22 | 37 / 9 | No. 314 | No. 6 | 
                         
                       | 
                    
| 
                        C00000615
                        
                           | 
                      
                        Caffeic acid
                         | 
                      
                        CHEMBL145
                         CHEMBL1320034  | 
                      68 / 64 / 63 | No. 904 | No. 6 | 
                         
                       | 
                    
| accession | description | class description | KNApSAcK metabolite in interactions | 
                          # of diseases
                           (OMIM / KEGG)  | 
                      
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00000674 C00002724 C00003817 | 1 / 0 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00000674 C00002724 C00003817 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00000674 C00002724 C00003817 | 0 / 1 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00000674 C00002724 C00003817 | 1 / 1 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00000674 C00002724 C00003817 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 C00000674 C00001017 C00003817 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00000674 C00002724 C00003817 | 0 / 0 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 C00000674 C00002724 C00003817 | 3 / 2 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00000674 C00002724 C00003817 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00000674 C00002724 C00003817 | 1 / 1 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00000674 C00002724 C00003817 | 3 / 3 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000615 C00000674 C00002724 C00003817 | 0 / 3 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00000674 C00002724 C00003817 | 0 / 1 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 C00000674 C00002724 C00003817 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00000615 C00000674 C00003817 | 1 / 1 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 C00000674 C00003817 | 1 / 2 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00000674 C00003817 | 2 / 2 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 C00000674 C00003817 | 3 / 1 | 
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000674 C00001017 C00003817 | 2 / 0 | 
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 C00000674 C00003817 | 1 / 1 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000674 C00001017 C00003817 | 4 / 1 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00000674 C00002724 | 0 / 0 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 C00000674 C00003817 | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00000674 C00002724 C00003817 | 0 / 1 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00000615 C00000674 C00003817 | 11 / 10 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000674 C00001017 C00003817 | 0 / 0 | 
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 C00000674 C00003817 | 0 / 0 | 
| P06239 | Tyrosine-protein kinase Lck | Src | C00000674 C00002724 C00003817 | 0 / 1 | 
| O75496 | Geminin | Unclassified protein | C00000674 C00002724 C00003817 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 C00000674 C00002724 | 0 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000674 C00002724 C00003817 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00000674 C00003817 | 4 / 3 | 
| O00255 | Menin | Unclassified protein | C00000615 C00000674 C00003817 | 2 / 5 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 C00003817 | 0 / 0 | 
| Q15046 | Lysine--tRNA ligase | Enzyme | C00000674 C00003817 | 2 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P14780 | Matrix metalloproteinase-9 | M10A | C00000615 C00000674 | 2 / 2 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P15121 | Aldose reductase | Enzyme | C00000615 C00002724 | 0 / 0 | 
| P04062 | Glucosylceramidase | Enzyme | C00000674 C00003817 | 6 / 4 | 
| O95271 | Tankyrase-1 | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P06746 | DNA polymerase beta | Enzyme | C00000615 C00000674 | 0 / 0 | 
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000615 C00002724 | 3 / 0 | 
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 C00002724 | 2 / 2 | 
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00000674 C00003817 | 0 / 0 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 C00003817 | 0 / 0 | 
| P22303 | Acetylcholinesterase | Hydrolase | C00000674 C00003817 | 1 / 0 | 
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000615 C00002724 | 0 / 0 | 
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000674 C00003817 | 1 / 1 | 
| Q00534 | Cyclin-dependent kinase 6 | CMGC serine/threonine protein kinase family | C00000674 C00003817 | 1 / 0 | 
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00000674 C00003817 | 0 / 0 | 
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000674 C00003817 | 0 / 0 | 
| Q9H2K2 | Tankyrase-2 | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P08183 | Multidrug resistance protein 1 | drug | C00000674 C00003817 | 1 / 0 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000674 C00003817 | 0 / 0 | 
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000674 C00003817 | 0 / 0 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00000674 C00003817 | 0 / 1 | 
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 C00003817 | 5 / 2 | 
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00000674 C00003817 | 0 / 0 | 
| Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00000674 C00003817 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00000674 C00003817 | 1 / 1 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00000674 C00003817 | 1 / 4 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 C00000674 | 0 / 0 | 
| P08253 | 72 kDa type IV collagenase | M10A | C00000615 C00000674 | 1 / 3 | 
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000615 C00003817 | 1 / 8 | 
| P10275 | Androgen receptor | NR3C4 | C00000674 C00003817 | 3 / 4 | 
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00000674 C00003817 | 0 / 0 | 
| P06280 | Alpha-galactosidase A | Enzyme | C00000615 C00000674 | 1 / 1 | 
| O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 | 
| P06276 | Cholinesterase | Hydrolase | C00000674 C00003817 | 0 / 0 | 
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000674 C00003817 | 4 / 4 | 
| P14679 | Tyrosinase | Oxidoreductase | C00000615 C00000674 | 4 / 2 | 
| Q9Y3R4 | Sialidase-2 | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00000674 C00003817 | 7 / 37 | 
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 | 
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00000674 C00003817 | 0 / 0 | 
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00000674 C00003817 | 0 / 0 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00000674 C00003817 | 1 / 1 | 
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000674 C00003817 | 1 / 1 | 
| Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 | 
| P03956 | Interstitial collagenase | M10A | C00000615 C00000674 | 0 / 1 | 
| P09874 | Poly [ADP-ribose] polymerase 1 | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00000674 C00003817 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00000674 C00003817 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000674 C00003817 | 2 / 0 | 
| P49840 | Glycogen synthase kinase-3 alpha | Gsk | C00000674 C00003817 | 0 / 0 | 
| P10145 | Interleukin-8 | Secreted protein | C00002724 C00003817 | 0 / 0 | 
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00000674 C00003817 | 4 / 2 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00000674 | 1 / 1 | 
| P41143 | Delta-type opioid receptor | Opioid receptor | C00003817 | 0 / 0 | 
| Q92731 | Estrogen receptor beta | NR3A2 | C00003817 | 0 / 1 | 
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00003817 | 0 / 0 | 
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00002724 | 0 / 0 | 
| P00915 | Carbonic anhydrase 1 | Lyase | C00000615 | 0 / 0 | 
| P09769 | Tyrosine-protein kinase Fgr | Src | C00003817 | 0 / 0 | 
| Q15418 | Ribosomal protein S6 kinase alpha-1 | Rskb | C00003817 | 0 / 0 | 
| O15264 | Mitogen-activated protein kinase 13 | p38 | C00003817 | 0 / 0 | 
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00002724 | 1 / 2 | 
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000615 | 0 / 0 | 
| Q12791 | Calcium-activated potassium channel subunit alpha-1 | KCNM, KCa1.x | C00003817 | 1 / 1 | 
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000615 | 0 / 0 | 
| O43570 | Carbonic anhydrase 12 | Lyase | C00000615 | 1 / 2 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001017 | 0 / 0 | 
| P68871 | Hemoglobin subunit beta | Secreted protein | C00003817 | 4 / 4 | 
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000615 | 0 / 0 | 
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000674 | 0 / 0 | 
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00003817 | 2 / 2 | 
| O75582 | Ribosomal protein S6 kinase alpha-5 | CAMK serine/threonine protein kinase MSKB subfamily | C00003817 | 0 / 0 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00003817 | 5 / 3 | 
| P23280 | Carbonic anhydrase 6 | Lyase | C00000615 | 0 / 0 | 
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00002724 | 0 / 0 | 
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00003817 | 0 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00003817 | 2 / 3 | 
| P04745 | Alpha-amylase 1 | Enzyme | C00000674 | 0 / 0 | 
| P45452 | Collagenase 3 | M10A | C00000674 | 1 / 1 | 
| P49137 | MAP kinase-activated protein kinase 2 | CAMK serine/threonine protein kinase MAPKAPK | C00003817 | 0 / 0 | 
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000674 | 2 / 0 | 
| Q96RI1 | Bile acid receptor | NR1H4 | C00003817 | 0 / 0 | 
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 | 0 / 0 | 
| P11387 | DNA topoisomerase 1 | Isomerase | C00000674 | 0 / 0 | 
| P56817 | Beta-secretase 1 | A1A | C00003817 | 0 / 0 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00000674 | 1 / 0 | 
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000615 | 0 / 1 | 
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00000674 | 0 / 0 | 
| Q9Y4K4 | Mitogen-activated protein kinase kinase kinase kinase 5 | STE serine/threonine protein kinase KHS subfamily | C00003817 | 0 / 0 | 
| P51570 | Galactokinase | Enzyme | C00000674 | 1 / 1 | 
| P54132 | Bloom syndrome protein | Enzyme | C00000674 | 1 / 2 | 
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00003817 | 1 / 1 | 
| P51692 | Signal transducer and activator of transcription 5B | Unclassified protein | C00002724 | 1 / 1 | 
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000615 | 0 / 0 | 
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 | 
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003817 | 1 / 1 | 
| P23443 | Ribosomal protein S6 kinase beta-1 | p70 | C00003817 | 0 / 0 | 
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00003817 | 0 / 0 | 
| P49327 | Fatty acid synthase | Transferase | C00000674 | 0 / 0 | 
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00003817 | 0 / 0 | 
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 | 0 / 0 | 
| O14763 | Tumor necrosis factor receptor superfamily member 10B | Unclassified protein | C00000674 | 1 / 0 | 
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00003817 | 0 / 0 | 
| P00918 | Carbonic anhydrase 2 | Lyase | C00000615 | 1 / 2 | 
| P68400 | Casein kinase II subunit alpha | Ck2 | C00003817 | 0 / 0 | 
| P35372 | Mu-type opioid receptor | Opioid receptor | C00003817 | 0 / 0 | 
| Q8IW41 | MAP kinase-activated protein kinase 5 | CAMK serine/threonine protein kinase MAPKAPK | C00003817 | 0 / 0 | 
| O75116 | Rho-associated protein kinase 2 | Rock | C00003817 | 0 / 0 | 
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00003817 | 0 / 0 | 
| P07948 | Tyrosine-protein kinase Lyn | Src | C00003817 | 0 / 0 | 
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00003817 | 0 / 0 | 
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003817 | 0 / 0 | 
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00003817 | 4 / 1 | 
| O00141 | Serine/threonine-protein kinase Sgk1 | AGC serine/threonine protein kinase SGK subfamily | C00003817 | 0 / 0 | 
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00000674 | 0 / 1 | 
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00003817 | 0 / 0 | 
| O14757 | Serine/threonine-protein kinase Chk1 | Chk1 | C00003817 | 0 / 0 | 
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00003817 | 0 / 0 | 
| P39900 | Macrophage metalloelastase | M10A | C00000674 | 0 / 0 | 
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00003817 | 1 / 0 | 
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000615 | 1 / 0 | 
| P17252 | Protein kinase C alpha type | Alpha | C00003817 | 0 / 0 | 
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 | 4 / 2 | 
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003817 | 5 / 1 | 
| P43166 | Carbonic anhydrase 7 | Lyase | C00000615 | 0 / 0 | 
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00003817 | 0 / 0 | 
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00002724 | 0 / 0 | 
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000615 | 0 / 0 | 
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000615 | 0 / 0 | 
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003817 | 0 / 0 | 
| P07451 | Carbonic anhydrase 3 | Lyase | C00000615 | 0 / 0 | 
| P41240 | Tyrosine-protein kinase CSK | Csk | C00003817 | 0 / 0 | 
| Q04760 | Lactoylglutathione lyase | Enzyme | C00000674 | 0 / 0 | 
| P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Ampk | C00003817 | 0 / 0 | 
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00003817 | 0 / 0 | 
| P43405 | Tyrosine-protein kinase SYK | Syk | C00003817 | 0 / 0 | 
| P08254 | Stromelysin-1 | M10A | C00000674 | 1 / 0 | 
| Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | C00003817 | 1 / 0 | 
| P22748 | Carbonic anhydrase 4 | Lyase | C00000615 | 1 / 1 | 
| P53778 | Mitogen-activated protein kinase 12 | p38 | C00003817 | 0 / 0 | 
| Q12794 | Hyaluronidase-1 | Enzyme | C00000615 | 1 / 2 | 
| O15530 | 3-phosphoinositide-dependent protein kinase 1 | Pdk1 | C00003817 | 0 / 0 | 
| P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 | 
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00003817 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000674 | 0 / 0 | 
| P40225 | Thrombopoietin | Unclassified protein | C00003817 | 1 / 1 | 
| P42224 | Signal transducer and activator of transcription 1-alpha/beta | Unclassified protein | C00002724 | 3 / 3 | 
| Q15759 | Mitogen-activated protein kinase 11 | p38 | C00003817 | 0 / 0 | 
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00003817 | 0 / 0 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003817 | 1 / 0 | 
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 | 0 / 0 | 
| P14618 | Pyruvate kinase PKM | Enzyme | C00003817 | 0 / 0 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003817 | 2 / 0 | 
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00003817 | 0 / 0 | 
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00003817 | 0 / 0 | 
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00003817 | 1 / 0 | 
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00003817 | 1 / 1 | 
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00003817 | 0 / 0 | 
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00003817 | 1 / 1 | 
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00003817 | 0 / 0 | 
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00003817 | 0 / 0 | 
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00003817 | 0 / 0 | 
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00003817 | 0 / 0 | 
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00003817 | 0 / 0 | 
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00003817 | 0 / 0 | 
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00003817 | 0 / 0 | 
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00003817 | 4 / 2 | 
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00003817 | 0 / 0 | 
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00003817 | 0 / 0 | 
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00003817 | 1 / 0 | 
| P45983 | Mitogen-activated protein kinase 8 | Jnk | C00003817 | 0 / 0 | 
| P53779 | Mitogen-activated protein kinase 10 | Jnk | C00003817 | 0 / 1 | 
| P45984 | Mitogen-activated protein kinase 9 | Jnk | C00003817 | 0 / 0 | 
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000615 | 1 / 0 | 
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 | 0 / 0 | 
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00003817 | 3 / 0 | 
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00003817 | 0 / 0 | 
| P22694 | cAMP-dependent protein kinase catalytic subunit beta | Pka | C00003817 | 0 / 0 | 
| P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00003817 | 0 / 0 | 
| P22612 | cAMP-dependent protein kinase catalytic subunit gamma | Pka | C00003817 | 0 / 0 | 
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 | 
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 | 
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00003817 | 0 / 0 | 
| Q9HCP0 | Casein kinase I isoform gamma-1 | Ck1 | C00003817 | 0 / 0 | 
| P48730 | Casein kinase I isoform delta | Ck1 | C00003817 | 1 / 0 | 
| P49674 | Casein kinase I isoform epsilon | Ck1 | C00003817 | 0 / 0 | 
| P78368 | Casein kinase I isoform gamma-2 | Ck1 | C00003817 | 0 / 0 | 
| P48729 | Casein kinase I isoform alpha | Ck1 | C00003817 | 0 / 0 | 
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00003817 | 1 / 1 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00000674 | 2 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 8839 | WISP2, CCN5, CT58, CTGF-L | WNT1 inducible signaling pathway protein 2 | 
                          C00000674
                          C00003817
                           | 
                      
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A | 
                          C00000674
                          C00003817
                           | 
                      
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 | 
                          C00000674
                          C00003817
                           | 
                      
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | 
                          C00000674
                          C00003817
                           | 
                      
| 7161 | TP73, P73 | tumor protein p73 | 
                          C00000674
                          C00003817
                           | 
                      
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 | 
                          C00000674
                          C00003817
                           | 
                      
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 | 
                          C00000674
                          C00003817
                           | 
                      
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor | 
                          C00000674
                          C00003817
                           | 
                      
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E | 
                          C00000674
                          C00003817
                           | 
                      
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A | 
                          C00000674
                          C00003817
                           | 
                      
| 1950 | EGF, HOMG4, URG | epidermal growth factor | 
                          C00000674
                          C00002724
                           | 
                      
| 8000 | PSCA, PRO232 | prostate stem cell antigen | 
                          C00000674
                          C00003817
                           | 
                      
| 4793 | NFKBIB, IKBB, TRIP9 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 
                          C00000674
                          C00003817
                           | 
                      
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 
                          C00000674
                          C00003817
                           | 
                      
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) | 
                          C00000674
                          C00003817
                           | 
                      
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | 
                          C00000674
                          C00003817
                           | 
                      
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) | 
                          C00000674
                          C00003817
                           | 
                      
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) | 
                          C00000674
                          C00003817
                           | 
                      
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene | 
                          C00000674
                          C00003817
                           | 
                      
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 | 
                          C00000674
                          C00003817
                           | 
                      
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 | 
                          C00000674
                          C00003817
                           | 
                      
| 5241 | PGR, NR3C3, PR | progesterone receptor | 
                          C00002724
                          C00003817
                           | 
                      
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog | 
                          C00000674
                          C00003817
                           | 
                      
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) | 
                          C00000674
                          C00003817
                           | 
                      
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) | 
                          C00000674
                          C00003817
                           | 
                      
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 | 
                          C00000674
                          C00003817
                           | 
                      
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | 
                          C00000674
                          C00003817
                           | 
                      
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | 
                          C00000674
                          C00003817
                           | 
                      
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | 
                          C00000674
                          C00003817
                           | 
                      
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 
                          C00000674
                          C00003817
                           | 
                      
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 
                          C00000674
                          C00003817
                           | 
                      
| 983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | 
                          C00000674
                          C00003817
                           | 
                      
| 958 | CD40, Bp50, CDW40, TNFRSF5, p50 | CD40 molecule, TNF receptor superfamily member 5 | 
                          C00000674
                          C00003817
                           | 
                      
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) | 
                          C00002724
                          C00003817
                           | 
                      
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) | 
                          C00000674
                          C00002724
                           | 
                      
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) | 
                          C00002724
                          C00003817
                           | 
                      
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) | 
                          C00002724
                          C00003817
                           | 
                      
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 
                          C00000674
                          C00003817
                           | 
                      
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor | 
                          C00000674
                          C00003817
                           | 
                      
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | 
                          C00000674
                          C00003817
                           | 
                      
| 891 | CCNB1, CCNB | cyclin B1 | 
                          C00000674
                          C00003817
                           | 
                      
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 | 
                          C00000674
                          C00003817
                           | 
                      
| 847 | CAT | catalase (EC:1.11.1.6) | 
                          C00000674
                          C00003817
                           | 
                      
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | 
                          C00000674
                          C00003817
                           | 
                      
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) | 
                          C00000674
                          C00003817
                           | 
                      
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | 
                          C00000674
                          C00003817
                           | 
                      
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | 
                          C00000674
                          C00003817
                           | 
                      
| 47 | ACLY, ACL, ATPCL, CLATP | ATP citrate lyase (EC:2.3.3.8) | 
                          C00002724
                           | 
                      
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator | 
                          C00003817
                           | 
                      
| 7306 | TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN | tyrosinase-related protein 1 (EC:1.14.18.-) | 
                          C00002724
                           | 
                      
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) | 
                          C00002724
                           | 
                      
| 7295 | TXN, TRDX, TRX, TRX1 | thioredoxin | 
                          C00002724
                           | 
                      
| 7178 | TPT1, HRF, TCTP, p02, p23 | tumor protein, translationally-controlled 1 | 
                          C00002724
                           | 
                      
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | 
                          C00003817
                           | 
                      
| 6387 | CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B | chemokine (C-X-C motif) ligand 12 | 
                          C00003817
                           | 
                      
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic | 
                          C00003817
                           | 
                      
| 1584 | CYP11B1, CPN1, CYP11B, FHI, P450C11 | cytochrome P450, family 11, subfamily B, polypeptide 1 (EC:1.14.15.4) | 
                          C00003817
                           | 
                      
| 1586 | CYP17A1, CPT7, CYP17, P450C17, S17AH | cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) | 
                          C00003817
                           | 
                      
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | 
                          C00003817
                           | 
                      
| 6716 | SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22) | 
                          C00002724
                           | 
                      
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | 
                          C00003817
                           | 
                      
| 6649 | SOD3, EC-SOD | superoxide dismutase 3, extracellular (EC:1.15.1.1) | 
                          C00002724
                           | 
                      
| 1589 | CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B | cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10) | 
                          C00003817
                           | 
                      
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | 
                          C00003817
                           | 
                      
| 6256 | RXRA, NR2B1 | retinoid X receptor, alpha | 
                          C00002724
                           | 
                      
| 2064 | ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) | 
                          C00003817
                           | 
                      
| 5914 | RARA, NR1B1, RAR | retinoic acid receptor, alpha | 
                          C00002724
                           | 
                      
| 5886 | RAD23A, HHR23A, HR23A | RAD23 homolog A (S. cerevisiae) | 
                          C00002724
                           | 
                      
| 5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma | 
                          C00002724
                           | 
                      
| 8985 | PLOD3, LH3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) | 
                          C00002724
                           | 
                      
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) | 
                          C00003817
                           | 
                      
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 
                          C00003817
                           | 
                      
| 3284 | HSD3B2, HSD3B, HSDB, SDR11E2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) | 
                          C00003817
                           | 
                      
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | 
                          C00002724
                           | 
                      
| 4157 | MC1R, CMM5, MSH-R, SHEP2 | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) | 
                          C00002724
                           | 
                      
| 3852 | KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A | keratin 5 | 
                          C00002724
                           | 
                      
| 3552 | IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 | interleukin 1, alpha | 
                          C00002724
                           | 
                      
| 3315 | HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 | heat shock 27kDa protein 1 | 
                          C00002724
                           | 
                      
| 3036 | HAS1, HAS | hyaluronan synthase 1 (EC:2.4.1.212) | 
                          C00002724
                           | 
                      
| 2896 | GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN | granulin | 
                          C00002724
                           | 
                      
| 2246 | FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1 | fibroblast growth factor 1 (acidic) | 
                          C00002724
                           | 
                      
| 2201 | FBN2, CCA, DA9 | fibrillin 2 | 
                          C00002724
                           | 
                      
| 5562 | PRKAA1, AMPK, AMPKa1 | protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) | 
                          C00003817
                           | 
                      
| 2200 | FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 | fibrillin 1 | 
                          C00002724
                           | 
                      
| 1830 | DSG3, CDHF6, PVA | desmoglein 3 | 
                          C00002724
                           | 
                      
| 6198 | RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha | ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) | 
                          C00003817
                           | 
                      
| 114757 | CYGB, HGB, STAP | cytoglobin | 
                          C00002724
                           | 
                      
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | 
                          C00003817
                           | 
                      
| 6783 | SULT1E1, EST, EST-1, ST1E1, STE | sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) | 
                          C00003817
                           | 
                      
| 4512 | COX1, COI, MTCO1, MT-CO1 | cytochrome c oxidase subunit I | 
                          C00002724
                           | 
                      
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 | 
                          C00003817
                           | 
                      
| 1277 | COL1A1, OI4 | collagen, type I, alpha 1 | 
                          C00002724
                           | 
                      
| 999 | CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO | cadherin 1, type 1, E-cadherin (epithelial) | 
                          C00002724
                           | 
                      
| 960 | CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 | CD44 molecule (Indian blood group) | 
                          C00002724
                           | 
                      
| 367 | AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM | androgen receptor | 
                          C00002724
                           | 
                      
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) | 
                          C00003817
                           | 
                      
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) | 
                          C00003817
                           | 
                      
| 7402 | UTRN, DMDL, DRP, DRP1 | utrophin | 
                          C00003817
                           | 
                      
| 360 | AQP3, AQP-3, GIL | aquaporin 3 (Gill blood group) | 
                          C00002724
                           | 
                      
| 358 | AQP1, AQP-CHIP, CHIP28, CO | aquaporin 1 | 
                          C00002724
                           | 
                      
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 | 
                          C00003817
                           | 
                      
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 | 
                          C00000674
                           | 
                      
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor | 
                          C00000674
                           | 
                      
| 581 | BAX, BCL2L4 | BCL2-associated X protein | 
                          C00000674
                           | 
                      
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 | 
                          C00000674
                           | 
                      
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 | 
                          C00000674
                           | 
                      
| 890 | CCNA2, CCN1, CCNA | cyclin A2 | 
                          C00000674
                           | 
                      
| 972 | CD74, DHLAG, HLADG, II, Ia-GAMMA | CD74 molecule, major histocompatibility complex, class II invariant chain | 
                          C00000674
                           | 
                      
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) | 
                          C00000674
                           | 
                      
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 
                          C00000674
                           | 
                      
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) | 
                          C00000674
                           | 
                      
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) | 
                          C00000674
                           | 
                      
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) | 
                          C00000674
                           | 
                      
| 1958 | EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 | early growth response 1 | 
                          C00000674
                           | 
                      
| 2354 | FOSB, AP-1, G0S3, GOS3, GOSB | FBJ murine osteosarcoma viral oncogene homolog B | 
                          C00000674
                           | 
                      
| 4616 | GADD45B, GADD45BETA, MYD118 | growth arrest and DNA-damage-inducible, beta | 
                          C00000674
                           | 
                      
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta | 
                          C00000674
                           | 
                      
| 3726 | JUNB, AP-1 | jun B proto-oncogene | 
                          C00000674
                           | 
                      
| 3727 | JUND, AP-1 | jun D proto-oncogene | 
                          C00000674
                           | 
                      
| 5602 | MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK | mitogen-activated protein kinase 10 (EC:2.7.11.24) | 
                          C00000674
                           | 
                      
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) | 
                          C00000674
                           | 
                      
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) | 
                          C00000674
                           | 
                      
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 
                          C00000674
                           | 
                      
| 9572 | NR1D1, EAR1, THRA1, THRAL, ear-1, hRev | nuclear receptor subfamily 1, group D, member 1 | 
                          C00000674
                           | 
                      
| 5347 | PLK1, PLK, STPK13 | polo-like kinase 1 (EC:2.7.11.21) | 
                          C00000674
                           | 
                      
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | 
                          C00000674
                           | 
                      
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) | 
                          C00000674
                           | 
                      
| 2810 | SFN, YWHAS | stratifin | 
                          C00000674
                           | 
                      
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) | 
                          C00000674
                           | 
                      
| 29110 | TBK1, NAK, T2K | TANK-binding kinase 1 (EC:2.7.11.1) | 
                          C00000674
                           | 
                      
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) | 
                          C00000674
                           | 
                      
| 8743 | TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL | tumor necrosis factor (ligand) superfamily, member 10 | 
                          C00000674
                           | 
                      
| 10451 | VAV3 | vav 3 guanine nucleotide exchange factor | 
                          C00000674
                           | 
                      
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis | 
                          C00000674
                           | 
                      
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | 
                            Q99714
                             | 
                        
| #614279 | 46,xy sex reversal 8; srxy8 | 
                            P17516
                             P52895  | 
                        
| #202300 | Adrenocortical carcinoma, hereditary; adcc | 
                            P04637
                             | 
                        
| #615224 | Advanced sleep phase syndrome, familial, 2; fasps2 | 
                            P48730
                             | 
                        
| #103470 | Albinism, ocular, with sensorineural deafness | 
                            P14679
                             | 
                        
| #203100 | Albinism, oculocutaneous, type ia; oca1a | 
                            P14679
                             | 
                        
| #606952 | Albinism, oculocutaneous, type ib; oca1b | 
                            P14679
                             | 
                        
| #103780 | Alcohol dependence | 
                            P47869
                             | 
                        
| #300068 | Androgen insensitivity syndrome; ais | 
                            P10275
                             | 
                        
| #312300 | Androgen insensitivity, partial; pais | 
                            P10275
                             | 
                        
| #613546 | Aromatase deficiency | 
                            P11511
                             | 
                        
| #139300 | Aromatase excess syndrome; aexs | 
                            P11511
                             | 
                        
| #600807 | Asthma, susceptibility to | 
                            Q13093
                             | 
                        
| #608584 | Asthma-related traits, susceptibility to, 2 | 
                            Q6W5P4
                             | 
                        
| #209950 | Atypical mycobacteriosis, familial | 
                            P42224
                             | 
                        
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | 
                            P04637
                             | 
                        
| #613985 | Beta-thalassemia | 
                            P68871
                             | 
                        
| #603902 | Beta-thalassemia, dominant inclusion body type | 
                            P68871
                             | 
                        
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 | 
                            P22309
                             | 
                        
| #614490 | Blood group, junior system; jr | 
                            Q9UNQ0
                             | 
                        
| #210900 | Bloom syndrome; blm | 
                            P54132
                             | 
                        
| %606641 | Body mass index; bmi | 
                            P37231
                             | 
                        
| #114480 | Breast cancer | 
                            P31749
                             P38398  | 
                        
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 | 
                            P38398
                             | 
                        
| #300615 | Brunner syndrome | 
                            P21397
                             | 
                        
| #614162 | Candidiasis, familial, 7; candf7 | 
                            P42224
                             | 
                        
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 | 
                            Q02750
                             | 
                        
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | 
                            P02545
                             | 
                        
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | 
                            P02545
                             | 
                        
| #609338 | Carotid intimal medial thickness 1 | 
                            P37231
                             | 
                        
| #118300 | Charcot-marie-tooth disease and deafness | 
                            Q01453
                             | 
                        
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | 
                            P02545
                             | 
                        
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a | 
                            Q01453
                             | 
                        
| #613641 | Charcot-marie-tooth disease, recessive intermediate b; cmtrib | 
                            Q15046
                             | 
                        
| #114500 | Colorectal cancer; crc | 
                            P18054
                             P31749 P84022 Q14191  | 
                        
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 | 
                            P08254
                             | 
                        
| #615109 | Cowden syndrome 6; cws6 | 
                            P31749
                             | 
                        
| #218800 | Crigler-najjar syndrome, type i | 
                            P22309
                             P22310  | 
                        
| #606785 | Crigler-najjar syndrome, type ii | 
                            P22309
                             P22310  | 
                        
| #613916 | Deafness, autosomal recessive 89; dfnb89 | 
                            Q15046
                             | 
                        
| #119900 | Digital clubbing, isolated congenital | 
                            P15428
                             | 
                        
| #607208 | Dravet syndrome | 
                            P18507
                             | 
                        
| #609535 | Drug metabolism, poor, cyp2c19-related | 
                            P33261
                             | 
                        
| #608902 | Drug metabolism, poor, cyp2d6-related | 
                            P10635
                             | 
                        
| #237500 | Dubin-johnson syndrome; djs | 
                            Q92887
                             | 
                        
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | 
                            P02545
                             | 
                        
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 | 
                            P18507
                             | 
                        
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 | 
                            P28472
                             | 
                        
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 | 
                            O14764
                             | 
                        
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 | 
                            P14867
                             | 
                        
| #609820 | Erythrocytosis, familial, 3; ecyt3 | 
                            Q9GZT9
                             | 
                        
| #133239 | Esophageal cancer | 
                            P04637
                             P18054  | 
                        
| #615363 | Estrogen resistance; estrr | 
                            P03372
                             | 
                        
| #301500 | Fabry disease | 
                            P06280
                             | 
                        
| #600274 | Frontotemporal dementia; ftd | 
                            P10636
                             | 
                        
| #230200 | Galactokinase deficiency | 
                            P51570
                             | 
                        
| #608013 | Gaucher disease, perinatal lethal | 
                            P04062
                             | 
                        
| #230800 | Gaucher disease, type i | 
                            P04062
                             | 
                        
| #230900 | Gaucher disease, type ii | 
                            P04062
                             | 
                        
| #231000 | Gaucher disease, type iii | 
                            P04062
                             | 
                        
| #231005 | Gaucher disease, type iiic | 
                            P04062
                             | 
                        
| #609446 | Generalized epilepsy and paroxysmal dyskinesia; gepd | 
                            Q12791
                             | 
                        
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 | 
                            P18507
                             | 
                        
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 | 
                            P18507
                             | 
                        
| #143500 | Gilbert syndrome | 
                            P22309
                             P22310  | 
                        
| #137750 | Glaucoma 1, open angle, a; glc1a | 
                            Q16678
                             | 
                        
| #231300 | Glaucoma 3, primary congenital, a; glc3a | 
                            Q16678
                             | 
                        
| #137760 | Glaucoma, primary open angle; poag | 
                            Q16678
                             | 
                        
| #137800 | Glioma susceptibility 1; glm1 | 
                            O75874
                             P37231  | 
                        
| #232300 | Glycogen storage disease ii | 
                            P10253
                             | 
                        
| #245590 | Growth hormone insensitivity with immunodeficiency | 
                            P51692
                             | 
                        
| #139393 | Guillain-barre syndrome, familial; gbs | 
                            Q01453
                             | 
                        
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | 
                            Q03164
                             | 
                        
| #610140 | Heart-hand syndrome, slovenian type | 
                            P02545
                             | 
                        
| #140700 | Heinz body anemias | 
                            P68871
                             | 
                        
| #176670 | Hutchinson-gilford progeria syndrome; hgps | 
                            P02545
                             | 
                        
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant | 
                            P40763
                             | 
                        
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn | 
                            P22309
                             | 
                        
| #143860 | Hyperchlorhidrosis, isolated | 
                            O43570
                             | 
                        
| #145000 | Hyperparathyroidism 1; hrpt1 | 
                            O00255
                             | 
                        
| #603373 | Hyperthyroidism, familial gestational | 
                            P16473
                             | 
                        
| #609152 | Hyperthyroidism, nonautoimmune | 
                            P16473
                             | 
                        
| #145900 | Hypertrophic neuropathy of dejerine-sottas | 
                            Q01453
                             | 
                        
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | 
                            P15428
                             | 
                        
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | 
                            P16473
                             | 
                        
| #147050 | Ige responsiveness, atopic; iger | 
                            Q13093
                             | 
                        
| #612244 | Inflammatory bowel disease 13; ibd13 | 
                            P08183
                             | 
                        
| #603932 | Intervertebral disc disease; idd | 
                            P14780
                             | 
                        
| #607785 | Juvenile myelomonocytic leukemia; jmml | 
                            Q06124
                             | 
                        
| #151100 | Leopard syndrome 1 | 
                            Q06124
                             | 
                        
| #601626 | Leukemia, acute myeloid; aml | 
                            P36888
                             | 
                        
| #151623 | Li-fraumeni syndrome 1; lfs1 | 
                            P04637
                             | 
                        
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | 
                            P02545
                             | 
                        
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | 
                            P37231
                             | 
                        
| #613795 | Loeys-dietz syndrome, type 3; lds3 | 
                            P84022
                             | 
                        
| #613688 | Long qt syndrome 2; lqt2 | 
                            Q12809
                             | 
                        
| #211980 | Lung cancer | 
                            P00533
                             P04637  | 
                        
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | 
                            P02545
                             | 
                        
| #614104 | Mental retardation, autosomal dominant 7; mrd7 | 
                            Q13627
                             | 
                        
| #300705 | Mental retardation, x-linked 17; mrx17 | 
                            Q99714
                             | 
                        
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | 
                            Q99714
                             | 
                        
| #156250 | Metachondromatosis; metcds | 
                            Q06124
                             | 
                        
| #613073 | Metaphyseal anadysplasia 2; mandp2 | 
                            P14780
                             | 
                        
| #601492 | Mucopolysaccharidosis, type ix; mps9 | 
                            Q12794
                             | 
                        
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona | 
                            P08253
                             | 
                        
| #131100 | Multiple endocrine neoplasia, type i; men1 | 
                            O00255
                             | 
                        
| #613205 | Muscular dystrophy, congenital, lmna-related | 
                            P02545
                             | 
                        
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | 
                            P02545
                             | 
                        
| #613796 | Mycobacterial and viral infections, susceptibility to, autosomal recessive | 
                            P42224
                             | 
                        
| #607948 | Mycobacterium tuberculosis, susceptibility to | 
                            P11473
                             | 
                        
| #160900 | Myotonic dystrophy 1; dm1 | 
                            Q9NR56
                             | 
                        
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp | 
                            Q01453
                             | 
                        
| #257220 | Niemann-pick disease, type c1; npc1 | 
                            O15118
                             | 
                        
| #163950 | Noonan syndrome 1; ns1 | 
                            Q06124
                             | 
                        
| #601665 | Obesity | 
                            P37231
                             | 
                        
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 | 
                            P00918
                             | 
                        
| #167000 | Ovarian cancer | 
                            P38398
                             | 
                        
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 | 
                            P38398
                             | 
                        
| #260500 | Papilloma of choroid plexus; cpp | 
                            P04637
                             | 
                        
| #168600 | Parkinson disease, late-onset; pd | 
                            P04062
                             | 
                        
| #260540 | Parkinson-dementia syndrome | 
                            P10636
                             | 
                        
| #604229 | Peters anomaly | 
                            Q16678
                             | 
                        
| #172700 | Pick disease of brain | 
                            P10636
                             | 
                        
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | 
                            Q01196
                             | 
                        
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad | 
                            Q13093
                             | 
                        
| #176920 | Proteus syndrome | 
                            P31749
                             | 
                        
| #275210 | Restrictive dermopathy, lethal | 
                            P02545
                             | 
                        
| #600852 | Retinitis pigmentosa 17; rp17 | 
                            P22748
                             | 
                        
| #604906 | Schizophrenia 9; sczd9 | 
                            P49798
                             | 
                        
| #181500 | Schizophrenia; sczd | 
                            P49798
                             | 
                        
| #609620 | Short qt syndrome 1; sqt1 | 
                            Q12809
                             | 
                        
| #603903 | Sickle cell anemia | 
                            P68871
                             | 
                        
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 | 
                            P14679
                             | 
                        
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 | 
                            P10275
                             | 
                        
| #253300 | Spinal muscular atrophy, type i; sma1 | 
                            Q16637
                             | 
                        
| #253550 | Spinal muscular atrophy, type ii; sma2 | 
                            Q16637
                             | 
                        
| #253400 | Spinal muscular atrophy, type iii; sma3 | 
                            Q16637
                             | 
                        
| #271150 | Spinal muscular atrophy, type iv; sma4 | 
                            Q16637
                             | 
                        
| #183090 | Spinocerebellar ataxia 2; sca2 | 
                            Q99700
                             | 
                        
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | 
                            Q9NUW8
                             | 
                        
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type | 
                            P45452
                             | 
                        
| #275355 | Squamous cell carcinoma, head and neck; hnscc | 
                            O14763
                             P04637  | 
                        
| %612223 | Stature quantitative trait locus 11; stqtl11 | 
                            Q00534
                             | 
                        
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | 
                            P10636
                             | 
                        
| #187950 | Thrombocythemia 1; thcyt1 | 
                            P40225
                             | 
                        
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | 
                            P10828
                             | 
                        
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | 
                            P10828
                             | 
                        
| #145650 | Thyroid hormone resistance, selective pituitary; prth | 
                            P10828
                             | 
                        
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 | 
                            Q9UNQ0
                             | 
                        
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | 
                            P11473
                             | 
                        
| #277700 | Werner syndrome; wrn | 
                            Q14191
                             | 
                        
| #278300 | Xanthinuria, type i | 
                            P47989
                             | 
                        
| #278750 | Xeroderma pigmentosum, variant type; xpv | 
                            Q9Y253
                             | 
                        
| #112100 | Yt blood group antigen | 
                            P22303
                             | 
                        
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | 
                            O00255
                            (related)
                             P04637 (related)  | 
                        
| H00034 | Carcinoid | 
                            O00255
                            (related)
                             | 
                        
| H00045 | Malignant islet cell carcinoma | 
                            O00255
                            (related)
                             | 
                        
| H00246 | Primary hyperparathyroidism | 
                            O00255
                            (related)
                             | 
                        
| H01102 | Pituitary adenomas | 
                            O00255
                            (related)
                             | 
                        
| H00783 | Febrile seizures | 
                            O14764
                            (related)
                             P18507 (related)  | 
                        
| H00136 | Niemann-Pick disease type C (NPC) | 
                            O15118
                            (related)
                             | 
                        
| H01302 | Hyperchlorhidrosis isolated (HCHLH) | 
                            O43570
                            (related)
                             | 
                        
| H00021 | Renal cell carcinoma | 
                            O43570
                            (marker)
                             P04637 (marker) Q16790 (marker)  | 
                        
| H00016 | Oral cancer | 
                            P00533
                            (related)
                             P00533 (marker) P04637 (related) P04637 (marker) P40763 (related)  | 
                        
| H00017 | Esophageal cancer | 
                            P00533
                            (related)
                             P04637 (related) P04637 (marker) P35354 (related)  | 
                        
| H00018 | Gastric cancer | 
                            P00533
                            (related)
                             P04637 (related)  | 
                        
| H00022 | Bladder cancer | 
                            P00533
                            (related)
                             P04637 (related) P68871 (marker)  | 
                        
| H00028 | Choriocarcinoma | 
                            P00533
                            (related)
                             P03956 (related) P04637 (related) P08253 (related)  | 
                        
| H00030 | Cervical cancer | 
                            P00533
                            (related)
                             | 
                        
| H00042 | Glioma | 
                            P00533
                            (related)
                             P00533 (marker) P04637 (related) P04637 (marker)  | 
                        
| H00055 | Laryngeal cancer | 
                            P00533
                            (related)
                             P00533 (marker) P04637 (related) P04637 (marker)  | 
                        
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) | 
                            P00918
                            (related)
                             | 
                        
| H00436 | Osteopetrosis | 
                            P00918
                            (related)
                             | 
                        
| H00264 | Charcot-Marie-Tooth disease (CMT) | 
                            P02545
                            (related)
                             Q01453 (related) Q15046 (related)  | 
                        
| H00294 | Dilated cardiomyopathy (DCM) | 
                            P02545
                            (related)
                             | 
                        
| H00420 | Familial partial lipodystrophy (FPL) | 
                            P02545
                            (related)
                             P37231 (related)  | 
                        
| H00563 | Emery-Dreifuss muscular dystrophy | 
                            P02545
                            (related)
                             | 
                        
| H00590 | Congenital muscular dystrophies (CMD/MDC) | 
                            P02545
                            (related)
                             | 
                        
| H00593 | Limb-girdle muscular dystrophy (LGMD) | 
                            P02545
                            (related)
                             | 
                        
| H00601 | Hutchinson-Gilford progeria syndrome | 
                            P02545
                            (related)
                             | 
                        
| H00663 | Restrictive dermopathy | 
                            P02545
                            (related)
                             | 
                        
| H00665 | Mandibuloacral dysplasia | 
                            P02545
                            (related)
                             | 
                        
| H01216 | Left ventricular noncompaction (LVNC) | 
                            P02545
                            (related)
                             | 
                        
| H00026 | Endometrial Cancer | 
                            P03372
                            (marker)
                             P04637 (related) Q92731 (marker)  | 
                        
| H00066 | Lewy body dementia (LBD) | 
                            P04062
                            (related)
                             | 
                        
| H00126 | Gaucher disease | 
                            P04062
                            (related)
                             | 
                        
| H00426 | Defects in the degradation of ganglioside | 
                            P04062
                            (related)
                             | 
                        
| H00810 | Progressive myoclonic epilepsy (PME) | 
                            P04062
                            (related)
                             | 
                        
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | 
                            P04150
                            (related)
                             P11511 (related)  | 
                        
| H00004 | Chronic myeloid leukemia (CML) | 
                            P04637
                            (related)
                             Q01196 (related)  | 
                        
| H00005 | Chronic lymphocytic leukemia (CLL) | 
                            P04637
                            (related)
                             P28907 (marker)  | 
                        
| H00006 | Hairy-cell leukemia | 
                            P04637
                            (related)
                             | 
                        
| H00008 | Burkitt lymphoma | 
                            P04637
                            (related)
                             | 
                        
| H00009 | Adult T-cell leukemia | 
                            P04637
                            (related)
                             | 
                        
| H00010 | Multiple myeloma | 
                            P04637
                            (related)
                             | 
                        
| H00013 | Small cell lung cancer | 
                            P04637
                            (related)
                             | 
                        
| H00014 | Non-small cell lung cancer | 
                            P04637
                            (related)
                             | 
                        
| H00015 | Malignant pleural mesothelioma | 
                            P04637
                            (related)
                             | 
                        
| H00019 | Pancreatic cancer | 
                            P04637
                            (related)
                             P04637 (marker)  | 
                        
| H00020 | Colorectal cancer | 
                            P04637
                            (related)
                             P04637 (marker) P68871 (marker)  | 
                        
| H00025 | Penile cancer | 
                            P04637
                            (related)
                             P04637 (marker) P08253 (related) P14780 (related) P35354 (related)  | 
                        
| H00027 | Ovarian cancer | 
                            P04637
                            (related)
                             P38398 (related)  | 
                        
| H00029 | Vulvar cancer | 
                            P04637
                            (related)
                             | 
                        
| H00031 | Breast cancer | 
                            P04637
                            (related)
                             P38398 (related)  | 
                        
| H00032 | Thyroid cancer | 
                            P04637
                            (related)
                             P37231 (related)  | 
                        
| H00036 | Osteosarcoma | 
                            P04637
                            (related)
                             P08684 (marker)  | 
                        
| H00038 | Malignant melanoma | 
                            P04637
                            (related)
                             P14679 (marker)  | 
                        
| H00039 | Basal cell carcinoma | 
                            P04637
                            (related)
                             | 
                        
| H00040 | Squamous cell carcinoma | 
                            P04637
                            (related)
                             | 
                        
| H00041 | Kaposi's sarcoma | 
                            P04637
                            (related)
                             | 
                        
| H00044 | Cancer of the anal canal | 
                            P04637
                            (related)
                             | 
                        
| H00046 | Cholangiocarcinoma | 
                            P04637
                            (related)
                             P35354 (related)  | 
                        
| H00047 | Gallbladder cancer | 
                            P04637
                            (related)
                             | 
                        
| H00048 | Hepatocellular carcinoma | 
                            P04637
                            (related)
                             | 
                        
| H00881 | Li-Fraumeni syndrome | 
                            P04637
                            (related)
                             | 
                        
| H01007 | Choroid plexus papilloma | 
                            P04637
                            (related)
                             | 
                        
| H00093 | Combined immunodeficiencies (CIDs) | 
                            P06239
                            (related)
                             | 
                        
| H00125 | Fabry disease | 
                            P06280
                            (related)
                             | 
                        
| H00472 | Torg-Winchester syndrome | 
                            P08253
                            (related)
                             | 
                        
| H00069 | Glycogen storage diseases (GSD) | 
                            P10253
                            (related)
                             | 
                        
| H00024 | Prostate cancer | 
                            P10275
                            (related)
                             | 
                        
| H00062 | Spinal and bulbar muscular atrophy (SBMA) | 
                            P10275
                            (related)
                             | 
                        
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) | 
                            P10275
                            (related)
                             | 
                        
| H00609 | 46,XY disorders of sex development (Other) | 
                            P10275
                            (related)
                             | 
                        
| H00058 | Amyotrophic lateral sclerosis (ALS) | 
                            P10636
                            (related)
                             | 
                        
| H00077 | Progressive supranuclear palsy (PSP) | 
                            P10636
                            (related)
                             | 
                        
| H00078 | Frontotemporal lobar degeneration (FTLD) | 
                            P10636
                            (related)
                             | 
                        
| H00249 | Thyroid hormone resistance syndrome | 
                            P10828
                            (related)
                             | 
                        
| H00342 | Tuberculosis | 
                            P11473
                            (related)
                             | 
                        
| H00784 | Localized autosomal recessive hypotrichosis | 
                            P11473
                            (related)
                             | 
                        
| H01143 | Vitamin D-dependent rickets | 
                            P11473
                            (related)
                             | 
                        
| H00794 | Aromatase excess syndrome | 
                            P11511
                            (related)
                             | 
                        
| H01205 | Coumarin resistance | 
                            P11712
                            (related)
                             | 
                        
| H00168 | Oculocutaneous albinism (OCA) | 
                            P14679
                            (related)
                             | 
                        
| H00479 | Metaphyseal dysplasias | 
                            P14780
                            (related)
                             P45452 (related)  | 
                        
| H00808 | Idiopathic generalized epilepsies (IGEs) | 
                            P14867
                            (related)
                             P18507 (related)  | 
                        
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | 
                            P15428
                            (related)
                             | 
                        
| H01246 | Isolated congenital nail clubbing (ICNC) | 
                            P15428
                            (related)
                             | 
                        
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | 
                            P16473
                            (related)
                             | 
                        
| H01269 | Congenital hyperthyroidism | 
                            P16473
                            (related)
                             | 
                        
| H00548 | Brunner syndrome | 
                            P21397
                            (related)
                             | 
                        
| H00208 | Hyperbilirubinemia | 
                            P22309
                            (related)
                             Q92887 (related)  | 
                        
| H00527 | Retinitis pigmentosa (RP) | 
                            P22748
                            (related)
                             | 
                        
| H00539 | PTEN hamartoma tumor syndrome (PHTS) | 
                            P31749
                            (related)
                             | 
                        
| H01171 | Poor drug metabolism (PM) | 
                            P33261
                            (related)
                             | 
                        
| H00003 | Acute myeloid leukemia (AML) | 
                            P36888
                            (related)
                             Q01196 (related) Q01196 (marker) Q13951 (marker)  | 
                        
| H00409 | Type II diabetes mellitus | 
                            P37231
                            (related)
                             | 
                        
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) | 
                            P40225
                            (marker)
                             | 
                        
| H00107 | Other well-defined immunodeficiency syndromes | 
                            P40763
                            (related)
                             | 
                        
| H00089 | IFN-gamma/IL-12 axis | 
                            P42224
                            (related)
                             | 
                        
| H00363 | Candidiasis | 
                            P42224
                            (related)
                             | 
                        
| H01109 | Chronic mucocutaneous candidiasis (CMC) | 
                            P42224
                            (related)
                             | 
                        
| H00192 | Xanthinuria | 
                            P47989
                            (related)
                             | 
                        
| H00070 | Galactosemia | 
                            P51570
                            (related)
                             | 
                        
| H00931 | Growth hormone insensitivity with immunodeficiency | 
                            P51692
                            (related)
                             | 
                        
| H00606 | Early infantile epileptic encephalopathy | 
                            P53779
                            (related)
                             | 
                        
| H00094 | DNA repair defects | 
                            P54132
                            (related)
                             | 
                        
| H00296 | Defects in RecQ helicases | 
                            P54132
                            (related)
                             Q14191 (related)  | 
                        
| H00228 | Thalassemia | 
                            P68871
                            (related)
                             | 
                        
| H00229 | Sickle cell anemia (SCA) | 
                            P68871
                            (related)
                             | 
                        
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | 
                            Q01196
                            (related)
                             Q01196 (marker) Q03164 (related) Q03164 (marker)  | 
                        
| H00978 | Thrombocytopenia (THC) | 
                            Q01196
                            (related)
                             | 
                        
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) | 
                            Q01453
                            (related)
                             | 
                        
| H00523 | Noonan syndrome and related disorders | 
                            Q02750
                            (related)
                             Q06124 (related)  | 
                        
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | 
                            Q03164
                            (related)
                             | 
                        
| H01018 | Metachondromatosis | 
                            Q06124
                            (related)
                             | 
                        
| H01258 | Generalized epilepsy and paroxysmal dyskinesia (GEPD) | 
                            Q12791
                            (related)
                             | 
                        
| H00133 | Mucopolysaccharidosis type IX (MPS9) | 
                            Q12794
                            (related)
                             | 
                        
| H00421 | Mucopolysaccharidosis (MPS) | 
                            Q12794
                            (related)
                             | 
                        
| H00720 | Long QT syndrome | 
                            Q12809
                            (related)
                             | 
                        
| H00725 | Short QT syndrome | 
                            Q12809
                            (related)
                             | 
                        
| H00455 | Spinal muscular atrophy (SMA) | 
                            Q16637
                            (related)
                             | 
                        
| H00612 | Primary open angle glaucoma | 
                            Q16678
                            (related)
                             | 
                        
| H01075 | Peters anomaly | 
                            Q16678
                            (related)
                             | 
                        
| H01159 | Anterior segment dysgenesis (ASD) | 
                            Q16678
                            (related)
                             | 
                        
| H01203 | Primary congenital glaucoma (PCG) | 
                            Q16678
                            (related)
                             | 
                        
| H00063 | Spinocerebellar ataxia (SCA) | 
                            Q99700
                            (related)
                             Q9NUW8 (related)  | 
                        
| H00480 | Non-syndromic X-linked mental retardation | 
                            Q99714
                            (related)
                             | 
                        
| H00658 | Syndromic X-linked mental retardation | 
                            Q99714
                            (related)
                             | 
                        
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | 
                            Q99714
                            (related)
                             | 
                        
| H00236 | Congenital polycythemia | 
                            Q9GZT9
                            (related)
                             | 
                        
| H00403 | Disorders of nucleotide excision repair | 
                            Q9Y253
                            (related)
                             | 
                        
| MESH or OMIM | name | 
                            KNApSAcK
                             metabolite  | 
                        
|---|---|---|
| D056486 | Drug-Induced Liver Injury | 
                            C00002724
                             C00003817  | 
                        
| D003110 | Colonic Neoplasms | 
                            C00003817
                             | 
                        
| D006937 | Hypercholesterolemia | 
                            C00002724
                             | 
                        
| D006951 | Hyperlipoproteinemias | 
                            C00002724
                             | 
                        
| D015228 | Hypertriglyceridemia | 
                            C00002724
                             | 
                        
| D052456 | Hypoalphalipoproteinemias | 
                            C00002724
                             | 
                        
| D008545 | Melanoma | 
                            C00002724
                             | 
                        
| D009336 | Necrosis | 
                            C00002724
                             | 
                        
| D015431 | Weight Loss | 
                            C00002724
                             | 
                        
| D000257 | Adenoviridae Infections | 
                            C00003817
                             | 
                        
| D001943 | Breast Neoplasms | 
                            C00003817
                             | 
                        
| D000647 | Amnesia | 
                            C00002724
                             | 
                        
| D009361 | Neoplasm Invasiveness | 
                            C00003817
                             | 
                        
| D009362 | Neoplasm Metastasis | 
                            C00003817
                             | 
                        
| D011041 | Poisoning | 
                            C00003817
                             | 
                        
| D011471 | Prostatic Neoplasms | 
                            C00003817
                             | 
                        
| D009202 | Cardiomyopathies | 
                            C00000674
                             | 
                        
| D002386 | Cataract | 
                            C00000674
                             | 
                        
| D005483 | Flushing | 
                            C00000674
                             | 
                        
| D006529 | Hepatomegaly | 
                            C00000674
                             | 
                        
| D008103 | Liver Cirrhosis | 
                            C00000674
                             | 
                        
| D010051 | Ovarian Neoplasms | 
                            C00000674
                             |