Annona purpurea
Species
KNApSAcK Entry
| Organism name | Annona purpurea |
|---|---|
| Genus | Annona |
| Family | Annonaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Annona purpurea |
|---|---|
| Linked NCBI taxonomy ID | 1123437 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Annonaceae |
|---|---|
| ID | 22140 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Metabolite list (44)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005140
|
Afzelin
/ Kaempferol 3-O-alpha-rhamnoside / Kaempferol 3-O-alpha-L-rhamnopyranoside |
CHEMBL240528
CHEMBL515798 |
C477954
|
4 / 2 / 2 | No. 2 | No. 15 |
|
|
|
C00049895
|
Purpurediolin
/ (+)-Purpurediolin |
CHEMBL506442
CHEMBL453228 CHEMBL501275 CHEMBL1964526 |
No. 6 | No. 70 |
|
|||
|
C00044288
|
Purpureacin 2
|
CHEMBL1978689
|
No. 6 | No. 70 |
|
|||
|
C00001320
|
Purpureacin-1
|
CHEMBL25650
CHEMBL68350 CHEMBL345841 CHEMBL1971856 CHEMBL1997997 |
No. 6 | No. 70 |
|
|||
|
C00049896
|
Purpurenin
/ (+)-Purpurenin |
CHEMBL506418
|
No. 6 | No. 70 |
|
|||
|
C00041091
|
Purpuracenin
/ (+)-Purpuracenin |
CHEMBL443639
CHEMBL509800 CHEMBL447889 CHEMBL443955 CHEMBL2007510 |
No. 6 | No. 70 |
|
|||
|
C00026016
|
Predicentrine
/ (+)-Predicentrine |
CHEMBL404136
|
No. 20 | No. 4 |
|
|||
|
C00041045
|
Lirinidine
|
CHEMBL109473
CHEMBL2316500 |
C054613
|
No. 20 | No. 4 |
|
||
|
C00027238
|
Thalicmidine
/ Thaliporphine / (+)-Thaliporphine / (S)-O-Methylisoboldine |
CHEMBL1394328
CHEMBL1397308 |
C080702
|
20 / 26 / 56 | No. 20 | No. 4 |
|
|
|
C00049908
|
(-)-Glaucine
|
CHEMBL36536
CHEMBL228082 |
14 / 8 / 6 | No. 20 | No. 4 |
|
||
|
C00046983
|
(+)-Apoglaziovine
|
No. 20 | No. 4 |
|
||||
|
C00046981
|
(-)-Lirinidine
|
CHEMBL109473
CHEMBL2316500 |
No. 20 | No. 4 |
|
|||
|
C00025675
|
Lauroscholtzine
/ 2-O-Methylboldine / N-Methyllaurotetanine / (+)-N-Methyllaurotetanine |
CHEMBL464099
|
1 / 1 / 0 | No. 20 | No. 4 |
|
||
|
C00050251
|
Thalbaicalidine
|
CHEMBL518061
|
No. 20 | No. 4 |
|
|||
|
C00001872
|
Isocorydine
/ (+)-Isocorydine / L-(+)-Isocorydine / (S)-(+)-Isocorydine |
CHEMBL489525
CHEMBL1376826 |
14 / 7 / 10 | No. 20 | No. 4 |
|
||
|
C00027589
|
Purpureine
/ Thalicsimidin / (+)-Purpureine / Thalicsimidine |
No. 20 | No. 4 |
|
||||
|
C00025991
|
O-Nornuciferine
/ (-)-Nornuciferine / (-)-N-Methylasimilobine |
CHEMBL2316499
|
No. 20 | No. 4 |
|
|||
|
C00023774
|
Fucostanol
/ Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol |
CHEMBL66943
CHEMBL186373 CHEMBL400247 CHEMBL1568947 |
D013265
|
5 / 0 / 0 | 1 / 0 | No. 53 | No. 11 |
|
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00025935
|
Lysicamine
/ Oxonuciferine |
CHEMBL510090
|
C069090
|
No. 74 |
|
|||
|
C00001878
|
Liriodenine
/ Oxoushinsunine / Spermatheridine |
CHEMBL37736
|
C026980
|
5 / 3 / 1 | No. 74 |
|
||
|
C00027459
|
Oxopurpureine
|
CHEMBL456295
|
20 / 27 / 24 | No. 74 |
|
|||
|
C00027457
|
Oxoglaucine
/ O-Methylatheroline |
CHEMBL470881
|
C111587
|
25 / 27 / 24 | No. 74 |
|
||
|
C00001910
|
Reticuline
/ (+)-Reticuline |
CHEMBL235212
CHEMBL401501 CHEMBL464734 |
C003298
|
1 / 0 / 0 | No. 345 | No. 4 |
|
|
|
C00049964
|
7-Hydroxy-dehydroglaucine
|
CHEMBL517328
|
No. 416 |
|
||||
|
C00050054
|
Dehydrolirinidine
|
CHEMBL464773
|
No. 416 |
|
||||
|
C00027261
|
7-Hydroxydehydrothalicsimidine
|
No. 416 |
|
|||||
|
C00026002
|
Pallidine
/ (-)-Pallidine / (-)-Isosalutaridine |
No. 426 | No. 4 |
|
||||
|
C00025988
|
Sebiferine
/ (9R)-Sebiferine / O-Methylflavinantine / (+)-O-Methylflavinanthine / (+)-O-Methylflavinantine |
CHEMBL224744
CHEMBL490139 |
C024736
|
No. 426 | No. 4 |
|
||
|
C00027442
|
Norpallidine
|
No. 426 | No. 4 |
|
||||
|
C00019308
|
Doursterol
/ Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside |
CHEMBL197711
CHEMBL506678 CHEMBL2304043 |
C011015
|
5 / 4 / 2 | 0 / 3 | No. 520 |
|
|
|
C00050253
|
Thalicpureine
|
CHEMBL464772
|
No. 639 |
|
||||
|
C00001862
|
Glaziovine
/ L-Glaziovine / N-Methylcrotsparine / L-(-)-N-Methylcrotsparine |
CHEMBL1980854
|
C007847
|
No. 688 |
|
|||
|
C00025272
|
Stepharine
/ (+)-Stepharine |
CHEMBL463957
CHEMBL1975436 |
C009320
|
No. 688 |
|
|||
|
C00027161
|
Promucosine
|
No. 688 |
|
|||||
|
C00027479
|
Romucosine G
|
CHEMBL208310
|
1 / 1 / 0 | No. 889 |
|
|||
|
C00027478
|
Romucosine F
|
No. 889 |
|
|||||
|
C00047056
|
Isovanillin
|
CHEMBL275563
|
C093382
|
7 / 8 / 4 | No. 1003 |
|
||
|
C00002683
|
Vanillin
|
CHEMBL13883
|
18 / 8 / 9 | No. 1003 |
|
|||
|
C00030771
|
Methylparaben
/ p-Methoxycarbonylphenol |
CHEMBL325372
|
C015358
|
102 / 49 / 57 | 3 / 0 | No. 2169 |
|
|
|
C00027167
|
Thalifoline
|
CHEMBL1813177
|
No. 2199 |
|
||||
|
C00029536
|
p-Anisic acid
/ 4-Methoxybenzoic acid |
CHEMBL21932
|
C004520
|
3 / 2 / 3 | No. 2930 |
|
||
|
C00047097
|
Squamolone
|
CHEMBL506960
|
1 / 4 / 2 | No. 4369 |
|
|||
|
C00001490
|
Adenine
|
CHEMBL226345
|
D000225
|
52 / 44 / 38 | 1 / 6 | No. 6151 |
|
Human Protein / Gene in interactions
217 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001872 C00003672 C00005140 C00027238 C00027457 C00030771 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001872 C00003672 C00005140 C00027238 C00027457 C00030771 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001872 C00002683 C00027238 C00047056 C00049908 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001872 C00003672 C00027238 C00027457 C00030771 | 1 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001490 C00027238 C00027457 C00027459 C00030771 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002683 C00027238 C00027457 C00027459 | 2 / 2 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00027238 C00027457 C00027459 C00049908 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001872 C00027238 C00027457 C00049908 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003672 C00019308 C00023774 C00027457 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001872 C00027457 C00027459 C00049908 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001872 C00002683 C00030771 C00047056 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00027459 C00030771 C00047056 C00049908 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001872 C00003672 C00027457 C00030771 | 0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00027238 C00027457 C00027459 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00027457 C00027459 C00049908 | 1 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001490 C00002683 C00030771 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00001490 C00003672 C00019308 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00027238 C00027457 C00027459 | 1 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00001490 C00030771 C00047056 | 1 / 1 |
| P00734 | Prothrombin | S1A | C00003672 C00019308 C00047097 | 4 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001872 C00027238 C00049908 | 3 / 3 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001872 C00003672 C00030771 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00027457 C00027459 C00049908 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002683 C00003672 C00027457 | 1 / 1 |
| P29466 | Caspase-1 | C14 | C00027238 C00027457 C00030771 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001490 C00027457 C00027459 | 11 / 10 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00027457 C00027459 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00001490 C00030771 | 2 / 2 |
| P17252 | Protein kinase C alpha type | Alpha | C00001490 C00030771 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00003672 C00030771 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001872 C00027459 | 1 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00001490 C00030771 | 5 / 9 |
| P22303 | Acetylcholinesterase | Hydrolase | C00027479 C00030771 | 1 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001910 C00030771 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00019308 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00027457 C00047056 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00027238 C00027457 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00001490 C00030771 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00001490 C00030771 | 0 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00001490 C00030771 | 0 / 1 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00029536 C00030771 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00029536 C00030771 | 1 / 2 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00002683 C00030771 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00027238 C00030771 | 7 / 37 |
| P42858 | Huntingtin | Unclassified protein | C00027457 C00027459 | 1 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00027457 C00027459 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003672 C00019308 | 0 / 0 |
| Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001878 C00049908 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00001490 C00030771 | 1 / 8 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00002683 C00030771 | 0 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002683 C00023774 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00001490 C00030771 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00030771 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00030771 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00001872 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00030771 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00001490 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00030771 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00001490 | 0 / 0 |
| P30926 | Neuronal acetylcholine receptor subunit beta-4 | CHRN beta | C00001878 | 0 / 0 |
| P32297 | Neuronal acetylcholine receptor subunit alpha-3 | CHRN alpha | C00001878 | 1 / 0 |
| P17787 | Neuronal acetylcholine receptor subunit beta-2 | CHRN beta | C00001878 | 1 / 1 |
| P43681 | Neuronal acetylcholine receptor subunit alpha-4 | CHRN alpha | C00001878 | 1 / 1 |
| P54132 | Bloom syndrome protein | Enzyme | C00027238 | 1 / 2 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00030771 | 0 / 0 |
| Q9BQF6 | Sentrin-specific protease 7 | Enzyme | C00049908 | 0 / 0 |
| Q9GZR1 | Sentrin-specific protease 6 | Enzyme | C00049908 | 0 / 0 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00002683 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00030771 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00030771 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00030771 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00030771 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00030771 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00030771 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00030771 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00030771 | 0 / 0 |
| P31751 | RAC-beta serine/threonine-protein kinase | Akt | C00001490 | 2 / 2 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00030771 | 1 / 1 |
| O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | Other serine/threonine protein kinase | C00001490 | 0 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00030771 | 0 / 0 |
| Q13464 | Rho-associated protein kinase 1 | Rock | C00001490 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00030771 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00030771 | 1 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00030771 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00030771 | 1 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00030771 | 1 / 2 |
| O43353 | Receptor-interacting serine/threonine-protein kinase 2 | Ripk | C00001490 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00030771 | 0 / 0 |
| P07332 | Tyrosine-protein kinase Fes/Fps | Fer | C00001490 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00030771 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00030771 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00027457 | 2 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00030771 | 1 / 1 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00030771 | 0 / 1 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00030771 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00030771 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00030771 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00030771 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00030771 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00030771 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00030771 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00030771 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00030771 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00030771 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00030771 | 1 / 0 |
| P42574 | Caspase-3 | C14 | C00049908 | 0 / 0 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002683 | 1 / 1 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00030771 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00030771 | 0 / 0 |
| Q05397 | Focal adhesion kinase 1 | Fak | C00001490 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00030771 | 1 / 0 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00002683 | 0 / 0 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00002683 | 0 / 0 |
| Q99683 | Mitogen-activated protein kinase kinase kinase 5 | Ste11 | C00001490 | 0 / 0 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00030771 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00047056 | 7 / 3 |
| P15056 | Serine/threonine-protein kinase B-raf | Raf | C00001490 | 6 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00027457 | 1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00027238 | 3 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 |
| Q99816 | Tumor susceptibility gene 101 protein | Unclassified protein | C00001490 | 0 / 0 |
| Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00049908 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00030771 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00030771 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00030771 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00030771 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00030771 | 2 / 0 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00002683 | 1 / 1 |
| Q92793 | CREB-binding protein | Enzyme | C00027457 | 1 / 1 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00030771 | 1 / 0 |
| P16083 | Ribosyldihydronicotinamide dehydrogenase [quinone] | Enzyme | C00005140 | 0 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00030771 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00030771 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00030771 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00030771 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00027238 | 1 / 1 |
| Q96GD4 | Aurora kinase B | Aur | C00001490 | 0 / 0 |
| P49137 | MAP kinase-activated protein kinase 2 | CAMK serine/threonine protein kinase MAPKAPK | C00001490 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002683 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00030771 | 1 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00027459 | 1 / 4 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00030771 | 2 / 1 |
| P45983 | Mitogen-activated protein kinase 8 | Jnk | C00001490 | 0 / 0 |
| O14965 | Aurora kinase A | Aur | C00001490 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00030771 | 0 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00001490 | 1 / 3 |
| Q15303 | Receptor tyrosine-protein kinase erbB-4 | TK tyrosine-protein kinase EGFR subfamily | C00001490 | 0 / 0 |
| Q13177 | Serine/threonine-protein kinase PAK 2 | STE serine/threonine protein kinase PAKA subfamily | C00001490 | 0 / 0 |
| P45984 | Mitogen-activated protein kinase 9 | Jnk | C00001490 | 0 / 0 |
| P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Enzyme | C00001490 | 9 / 1 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00002683 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00030771 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00001490 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00030771 | 1 / 0 |
| P09884 | DNA polymerase alpha catalytic subunit | Transferase | C00023774 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00030771 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00030771 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00030771 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00030771 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00030771 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00030771 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00030771 | 0 / 0 |
| Q08881 | Tyrosine-protein kinase ITK/TSK | Tec | C00001490 | 1 / 1 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00030771 | 0 / 0 |
| O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Enzyme | C00001490 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00001490 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00027238 | 0 / 0 |
| P55210 | Caspase-7 | C14 | C00027238 | 0 / 0 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00001490 | 4 / 1 |
| Q15118 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial | Pdhk | C00001490 | 0 / 0 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00029536 | 1 / 1 |
| O00141 | Serine/threonine-protein kinase Sgk1 | AGC serine/threonine protein kinase SGK subfamily | C00001490 | 0 / 0 |
| P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | C00002683 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00030771 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00030771 | 0 / 0 |
| P98170 | E3 ubiquitin-protein ligase XIAP | Other cytosolic protein | C00005140 | 1 / 1 |
| P08246 | Neutrophil elastase | S1A | C00030771 | 2 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00027459 | 0 / 0 |
| P08069 | Insulin-like growth factor 1 receptor | TK tyrosine-protein kinase INSR subfamily | C00001490 | 1 / 3 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00030771 | 5 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00030771 | 2 / 2 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00030771 | 0 / 3 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00030771 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00025675 | 1 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00002683 | 3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00030771 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00030771 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00030771 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00030771 | 1 / 1 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00001490 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00030771 | 0 / 0 |
| P52333 | Tyrosine-protein kinase JAK3 | Jakb | C00001490 | 1 / 1 |
| P04049 | RAF proto-oncogene serine/threonine-protein kinase | Raf | C00001490 | 2 / 0 |
| P43405 | Tyrosine-protein kinase SYK | Syk | C00001490 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00001490 | 1 / 0 |
| P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Enzyme | C00001490 | 0 / 0 |
| Q06278 | Aldehyde oxidase | Enzyme | C00047056 | 0 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00027459 | 1 / 1 |
| Q2TB90 | Putative hexokinase HKDC1 | Enzyme | C00027459 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00027459 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00002683 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00027459 | 4 / 1 |
| O00255 | Menin | Unclassified protein | C00027238 | 2 / 5 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001872 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001872 | 1 / 4 |
| P22694 | cAMP-dependent protein kinase catalytic subunit beta | Pka | C00001490 | 0 / 0 |
| P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00001490 | 0 / 0 |
| P22612 | cAMP-dependent protein kinase catalytic subunit gamma | Pka | C00001490 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00023774 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00023774 | 0 / 0 |
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00001490 | 1 / 1 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00049908 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001490 | 1 / 1 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00030771
|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00030771
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00030771
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001490
|
| 10599 | SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 | solute carrier organic anion transporter family, member 1B1 |
C00023774
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (148)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #114480 | Breast cancer |
P31749
P42336 |
| #300615 | Brunner syndrome |
P21397
|
| #115150 | Cardiofaciocutaneous syndrome 1; cfc1 |
P15056
|
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P15056
P31749 P42336 P84022 |
| #612918 | Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi |
P42336
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #615108 | Cowden syndrome 5; cws5 |
P42336
|
| #615109 | Cowden syndrome 6; cws6 |
P31749
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P31751
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600513 | Epilepsy, nocturnal frontal lobe, 1; enfl1 |
P43681
|
| #605375 | Epilepsy, nocturnal frontal lobe, 3; enfl3 |
P17787
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #114550 | Hepatocellular carcinoma |
P42336
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #240900 | Hypoinsulinemic hypoglycemia with hemihypertrophy; hihghh |
P31751
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #270450 | Insulin-like growth factor i, resistance to |
P08069
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #182000 | Keratosis, seborrheic |
P42336
|
| #611554 | Leopard syndrome 2 |
P04049
|
| #613707 | Leopard syndrome 3 |
P15056
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 P15056 |
| #605027 | Lymphoma, non-hodgkin, familial |
P15056
|
| #613011 | Lymphoproliferative syndrome 1; lpfs1 |
Q08881
|
| #300635 | Lymphoproliferative syndrome, x-linked, 2; xlp2 |
P98170
|
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #602501 | Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap |
P42336
|
| #603387 | Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph |
P42336
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #611553 | Noonan syndrome 5; ns5 |
P04049
|
| #613706 | Noonan syndrome 7; ns7 |
P15056
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P42336 |
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #176920 | Proteus syndrome |
P31749
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #180849 | Rubinstein-taybi syndrome 1; rsts1 |
Q92793
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #600802 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative |
P52333
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #612052 | Smoking as a quantitative trait locus 3; sqtl3 |
P32297
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (116)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P31751 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P31751 (related) P42336 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
Q13315 (related) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
P08069 (related) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P15056 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) P15056 (related) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00050 | Synovial sarcoma |
P08069
(related)
|
| H01274 | Growth delay due to insulin-like growth factor I resistance |
P08069
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
P52333 (related) |
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00523 | Noonan syndrome and related disorders |
P15056
(related)
Q02750 (related) |
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00807 | Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) |
P17787
(related)
P43681 (related) |
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
Q06278 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
Q13315 (related) |
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P98170
(related)
Q08881 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00504 | Rubinstein-Taybi syndrome |
Q92793
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
9 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D002493 | Central Nervous System Diseases |
C00019308
|
| D003072 | Cognition Disorders |
C00019308
|
| D013118 | Spinal Cord Diseases |
C00019308
|
| D000855 | Anorexia |
C00001490
|
| D002779 | Cholestasis |
C00001490
|
| D056486 | Drug-Induced Liver Injury |
C00001490
|
| D007565 | Jaundice |
C00001490
|
| D009325 | Nausea |
C00001490
|
| D051437 | Renal Insufficiency |
C00001490
|