KCF-S cluster No. 426 (18 metabolites)

Corresponding Phytochemical cluster No. 4


KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Isoquinoline alkaloids 2

metabolites link (2)

br08003 Category KEGG ID KNApSAcK ID
Isoquinoline alkaloids C09334 C00001802
Isoquinoline alkaloids C05179 C00001916

Metabolite list (18)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001802 External link 512 Amurine
/ (+)-Amurine
C00001916 External link 512 Salutaridine
/ (+)-Salutaridine
CHEMBL402782
CHEMBL404097
C009270
3 / 4 / 2
C00002314 External link 512 Androcymbine
C001891
C00025629 External link 512 Sinoacutine
/ (-)-Sinoacutine
/ (-)-Salutaridine
CHEMBL402782
CHEMBL404097
3 / 4 / 2
C00025910 External link 512 Isosinoacutine
C00025988 External link 512 Sebiferine
/ (9R)-Sebiferine
/ O-Methylflavinantine
/ (+)-O-Methylflavinanthine
/ (+)-O-Methylflavinantine
CHEMBL224744
CHEMBL490139
C024736
C00026002 External link 512 Pallidine
/ (-)-Pallidine
/ (-)-Isosalutaridine
C00027366 External link 512 Flavinantine
/ (-)-Flavinantine
CHEMBL463084
1 / 4 / 2
C00027394 External link 512 Isosalutaridine
C00027426 External link 512 N-Methylflavinantine
C00027442 External link 512 Norpallidine
C00027443 External link 512 Norsalutaridine
C00028711 External link 512 Noramurine
C00028765 External link 512 O-Methylflavinine
C00028768 External link 512 Fissistigine C
/ O-Methylpallidine
CHEMBL224744
CHEMBL490139
C00036270 External link 512 (-)-Amurine
C00039866 External link 512 Norisosalutaridine
C00045477 External link 512 (+)-Flavinantine
CHEMBL463084
1 / 4 / 2

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00734 Prothrombin S1A C00001916 C00025629 C00027366 C00045477 4 / 2
P24941 Cyclin-dependent kinase 2 Cdc2 C00001916 C00025629 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00001916 C00025629 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (2)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)