PCIDB

KNApSAcK Metabolite C00025629

Metabolite

KNApSAcK Entry

id C00025629
Name Sinoacutine / (-)-Sinoacutine / (-)-Salutaridine
CAS RN 4090-18-0
Standard InChI InChI=1S/C19H21NO4/c1-20-7-6-19-10-16(24-3)14(21)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9-10,13,22H,6-8H2,1-3H3/t13-,19+/m0/s1
Standard InChI (Main Layer) InChI=1S/C19H21NO4/c1-20-7-6-19-10-16(24-3)14(21)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9-10,13,22H,6-8H2,1-3H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 426

Link

ChEMBL

By standard InChI CHEMBL402782
By standard InChI Main Layer CHEMBL402782 CHEMBL404097

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
eudicotyledons 22
Magnoliophyta 2

Family

family name count
Menispermaceae 13
Papaveraceae 8
Lauraceae 1
Berberidaceae 1
Annonaceae 1

List (25)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Antizoma angustifolia Miers 341008 Menispermaceae eudicotyledons Viridiplantae
Artabotrys uncinatus 225832 Annonaceae Magnoliophyta Viridiplantae
Ceratocapnos palaestinus 1095358 Papaveraceae eudicotyledons Viridiplantae
Corydalis cava 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis majori 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis ochroleuca 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis solida 38914 Papaveraceae eudicotyledons Viridiplantae
Corydalis stewartii 3463 Papaveraceae eudicotyledons Viridiplantae
Dehaasia longipedicellata 128612 Lauraceae Magnoliophyta Viridiplantae
Flatycapnos saxicola
Glaucium controruplicatum 56852 Papaveraceae eudicotyledons Viridiplantae
Nandina domestica 41776 Berberidaceae eudicotyledons Viridiplantae
Platycapnos saxicola 1095362 Papaveraceae eudicotyledons Viridiplantae
Sinomenium acutum Rehder & Wilson 152362 Menispermaceae eudicotyledons Viridiplantae
Stephania brachyandra Diels 152368 Menispermaceae eudicotyledons Viridiplantae
Stephania cepharantha Hayata 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania dielsiana Y.C.Wu 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania elegans Hook.& Thoms. 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania epigaea H.S.Lo 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania gracilenta Miers 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania mashanica H.S.Lo.et.B.N.Chang 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania micrantha H.S.Lo.et.M.Yang 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania officinarum 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania pierrei Diels (=S.erecta Craib) 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania yunnanensis H.S Lo 147243 Menispermaceae eudicotyledons Viridiplantae

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P24941 Cyclin-dependent kinase 2 Cdc2 CHEMBL404097 CHEMBL1067148 (1)
0 / 0
P00734 Prothrombin S1A CHEMBL402782 CHEMBL944432 (1)
4 / 2
P35372 Mu-type opioid receptor Opioid receptor CHEMBL404097 CHEMBL925793 (1) CHEMBL925795 (1)
CHEMBL925796 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (2)

KEGG disease name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)