Organism name | Sinomenium acutum Rehder & Wilson |
---|---|
Genus | Sinomenium |
Family | Menispermaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Sinomenium |
---|---|
Linked NCBI taxonomy ID | 152362 |
Linked level | genus |
Family in NCBI taxonomy | Menispermaceae |
---|---|
ID | 3455 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | eudicotyledons |
---|---|
ID | 71240 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00025775 |
Bianfugenine
/ Dauriporphine |
C046294
|
No. 74 | |||||
C00026127 |
Dehydrodiscretine
/ Pseudojatrorrhizine |
CHEMBL220527
|
No. 155 | No. 4 | ||||
C00026048 |
Stepharanin
/ Stepharanine |
CHEMBL251229
|
1 / 0 / 1 | No. 155 | No. 4 | |||
C00026130 |
Epiberberine
|
CHEMBL1197637
|
C061432
|
22 / 34 / 27 | No. 155 | No. 4 | ||
C00025667 |
(+)-Laurifoline
|
CHEMBL235429
|
No. 286 | No. 4 | ||||
C00025596 |
8,14-Dihydrosalutaridine
/ (-)-8,14-dihydrosalutaridine |
No. 346 | No. 4 | |||||
C00025629 |
Sinoacutine
/ (-)-Sinoacutine / (-)-Salutaridine |
CHEMBL402782
CHEMBL404097 |
3 / 4 / 2 | No. 426 | No. 4 | |||
C00025765 |
Acutumine
|
CHEMBL391628
CHEMBL391835 CHEMBL1716763 |
1 / 0 / 0 | No. 915 | ||||
C00025858 |
Disinomenine
/ (+)-Disinomenine |
CHEMBL255668
|
No. 3422 | |||||
C00026034 |
Sinomendine
|
No. 4791 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q16637 | Survival motor neuron protein | Unclassified protein | C00026130 | 4 / 1 |
P06746 | DNA polymerase beta | Enzyme | C00026130 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00026130 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00026130 | 11 / 10 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025629 | 0 / 0 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00026130 | 1 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00026130 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00026130 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00026130 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00026130 | 7 / 3 |
Q9Y253 | DNA polymerase eta | Enzyme | C00026130 | 1 / 1 |
Q99816 | Tumor susceptibility gene 101 protein | Unclassified protein | C00026130 | 0 / 0 |
P00734 | Prothrombin | S1A | C00025629 | 4 / 2 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00026130 | 2 / 2 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00025765 | 0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00025629 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00026048 | 0 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00026130 | 0 / 0 |
Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00026130 | 1 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00026130 | 4 / 3 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00026130 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00026130 | 0 / 0 |
Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00026130 | 0 / 0 |
O00255 | Menin | Unclassified protein | C00026130 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00026130 | 1 / 2 |
Q9UBT2 | SUMO-activating enzyme subunit 2 | Enzyme | C00026130 | 0 / 0 |
Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00026130 | 0 / 0 |
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
#613679 | Prothrombin deficiency, congenital |
P00734
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#601367 | Stroke, ischemic |
P00734
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00223 | Inherited thrombophilia |
P00734
(related)
|
H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|