KCF-S cluster No. 74 (57 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (57)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Magnoliophyta	137
eudicotyledons	97
rosids	4
Liliopsida	3

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Cumulative family count

class name	count
Annonaceae	99
Menispermaceae	61
Papaveraceae	34
Lauraceae	16
Magnoliaceae	8
Hernandiaceae	6
Atherospermataceae	3
Pieridae	3
Aristolochiaceae	3
Rutaceae	2
Ranunculaceae	2
Asparagaceae	2
Siparunaceae	2
Rhamnaceae	1
Araceae	1
Euphorbiaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (57)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001812	Atheroline		C001827
C00001813	Atherospermidine		C064684
C00001878	Liriodenine / Oxoushinsunine / Spermatheridine	CHEMBL37736	C026980	5 / 3 / 1
C00024772	Oxocompostelline
C00024773	Oxocularine	CHEMBL510574
C00024774	Oxosarcocapnidine
C00024775	Oxosarcocapnine
C00024776	Oxosarcophylline
C00025319	Oxoxylopin / Oxoxylopine / Lanuginosine	CHEMBL389400		1 / 4 / 2
C00025339	Oxocrebanine / 8,9-Dimethoxyliriodenine
C00025340	Oxostephanine	CHEMBL521933
C00025341	Oxostephanosine
C00025349	Thailandine
C00025354	Uthongine
C00025773	Bianfugecine / 5,9-Dimethoxy-7H-dibenzo[de,h]quinolin-7-one		C046292
C00025774	Bianfugedine		C046293
C00025775	Bianfugenine / Dauriporphine		C046294
C00025782	Cassameridin / Cassameridine
C00025840	Dauriporphinoline
C00025849	Dicentrinone / Oxodicentrine	CHEMBL463284		1 / 0 / 0
C00025890	Liridine / Homomoschatoline / O-Methylmoschatoline / O-Methylisomoschatoline	CHEMBL227533
C00025898	Imenine
C00025935	Lysicamine / Oxonuciferine	CHEMBL510090	C069090
C00025940	Menisporphine
C00025992	Oxoanolobine
C00025993	Oxobuxifoline
C00025995	Oxonantenine	CHEMBL1270949
C00025996	Oxoputerine
C00026011	Peruvianine
C00026035	Splendidine		C457226
C00026052	Subsessiline / Splendaboline
C00026057	Telazoline
C00027142	Duguevalline
C00027145	Isomoschatoline
C00027298	Artabonatine C
C00027309	Cassamedine
C00027330	Glauvine / Corunnine
C00027337	Daurioxoisoporphine B	CHEMBL446816
C00027338	Daurioxoisoporphine C	CHEMBL1651051
C00027339	Daurioxoisoporphine D
C00027364	Fissiceine
C00027404	Kuafumine
C00027456	Oxoanolobine
C00027457	Oxoglaucine / O-Methylatheroline	CHEMBL470881	C111587	25 / 27 / 24
C00027459	Oxopurpureine	CHEMBL456295		20 / 27 / 24
C00027486	Teliglazine
C00027542	Hernandonine
C00027543	Hernanymphine
C00027581	Oxobuxifoline
C00027775	7-Oxodehydroasimilobine
C00027868	Annolatine
C00028596	Mollisine
C00028782	Oxocularicine
C00032676	7-Oxohernagine
C00039441	Isofiliformine	CHEMBL403551
C00050097	Filiformine
C00050252	Thalicminine	CHEMBL450614	C069511

Human Protein / Gene in interactions

40 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00027457 C00027459	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00027457 C00027459	4 / 3
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00027457 C00027459	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00027457 C00027459	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00027457 C00027459	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00027457 C00027459	2 / 2
P28482	Mitogen-activated protein kinase 1	Erk	C00027457 C00027459	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00027457 C00027459	1 / 2
P02545	Prelamin-A/C	Unclassified protein	C00027457 C00027459	11 / 10
P42858	Huntingtin	Unclassified protein	C00027457 C00027459	1 / 1
P39748	Flap endonuclease 1	Enzyme	C00027457 C00027459	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00027457 C00027459	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00027457	1 / 0
P43681	Neuronal acetylcholine receptor subunit alpha-4	CHRN alpha	C00001878	1 / 1
P32297	Neuronal acetylcholine receptor subunit alpha-3	CHRN alpha	C00001878	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00025849	0 / 0
Q14761	Protein tyrosine phosphatase receptor type C-associated protein	Enzyme	C00001878	0 / 0
P30926	Neuronal acetylcholine receptor subunit beta-4	CHRN beta	C00001878	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00027457	0 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00027457	2 / 0
P17787	Neuronal acetylcholine receptor subunit beta-2	CHRN beta	C00001878	1 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00027457	1 / 1
Q92793	CREB-binding protein	Enzyme	C00027457	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00027457	0 / 0
P00734	Prothrombin	S1A	C00025319	4 / 2
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00027459	1 / 4
P29466	Caspase-1	C14	C00027457	0 / 0
P06746	DNA polymerase beta	Enzyme	C00027457	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00027457	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00027457	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00027459	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00027459	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00027459	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00027459	4 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00027457	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00027457	0 / 0
Q2TB90	Putative hexokinase HKDC1	Enzyme	C00027459	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00027459	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00027457	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00027459	1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions