Stephania epigaea H.S.Lo

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Stephania epigaea H.S.Lo
Genus	Stephania
Family	Menispermaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Stephania
Linked NCBI taxonomy ID	147243
Linked level	genus

Family

Family in NCBI taxonomy	Menispermaceae
ID	3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001870	Isobebeerin / Isobebeerine / Isochondodendrine	CHEMBL509310 CHEMBL1169628				No. 10	No. 4
C00025602	l-Curine / (-)-Curine / l-Bebeerine / Aristolochine / (-)-Bebeerine / Aristolochine(C36 alkaloid)	CHEMBL1169627		13 / 6 / 5		No. 10	No. 4
C00025604	Cycleanine / (-)-Cycleanine	CHEMBL1711244 CHEMBL1983719	C037098	7 / 1 / 1		No. 10	No. 4
C00025607	NSC 251699 / L-Dicentrine / (-)-Dicentrine / (R)-(-)-Dicentrine	CHEMBL464748 CHEMBL478754		15 / 20 / 16		No. 20	No. 4
C00025630	Stephanine / l-Stephanine / (-)-Stephanine / (R)-(-)-Stephanine	CHEMBL601020	C054160	1 / 0 / 0		No. 20	No. 4
C00026150	Tetrahydropalmatine / dl-Tetrahydropalmatine / (+/-)-Tetrahydropalmatine	CHEMBL187892 CHEMBL487182 CHEMBL2334889		8 / 5 / 2		No. 37	No. 4
C00025913	Isostephodeline / (+)-Isostephodeline / (+)-14-Epierromangine					No. 346	No. 4
C00025846	Dehydrostephanine / 1,2-Methylenedioxy-8-methoxydehydroaporphine		C030171			No. 416
C00025842	Dehydrodicentrine	CHEMBL456942				No. 416
C00025629	Sinoacutine / (-)-Sinoacutine / (-)-Salutaridine	CHEMBL402782 CHEMBL404097		3 / 4 / 2		No. 426	No. 4
C00026072	Ushinsunine / Micheline A / (-)-Ushinsunine	CHEMBL221034 CHEMBL1617041 CHEMBL2009013		1 / 0 / 0		No. 553
C00025984	Oliveroline / (-)-Oliveroline	CHEMBL221034 CHEMBL1617041 CHEMBL2009013		1 / 0 / 0		No. 553

Human Protein / Gene in interactions

37 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P24941	Cyclin-dependent kinase 2	Cdc2	C00025607 C00025629 C00025630	0 / 0
O75496	Geminin	Unclassified protein	C00025602 C00025604 C00025607	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00025602 C00025604 C00025607	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00025604 C00025607	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00025602 C00025607	4 / 3
O14757	Serine/threonine-protein kinase Chk1	Chk1	C00025984 C00026072	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00025602 C00025629	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00025602 C00025604	1 / 1
P43351	DNA repair protein RAD52 homolog	Unclassified protein	C00025602 C00025607	0 / 0
P00734	Prothrombin	S1A	C00025629	4 / 2
P14416	D(2) dopamine receptor	Dopamine receptor	C00026150	2 / 0
P39748	Flap endonuclease 1	Enzyme	C00025607	0 / 0
P42858	Huntingtin	Unclassified protein	C00025602	1 / 1
P47898	5-hydroxytryptamine receptor 5A	Serotonin receptor	C00025602	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00025602	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00026150	1 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00025604	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00025607	1 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00025607	1 / 0
P13726	Tissue factor	Membrane receptor	C00026150	0 / 0
P03372	Estrogen receptor	NR3A1	C00026150	1 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00026150	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00025607	11 / 10
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00026150	0 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00025604	0 / 0
P06746	DNA polymerase beta	Enzyme	C00025607	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00026150	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00025607	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00026150	1 / 0
O43603	Galanin receptor type 2	Galanin receptor	C00025602	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00025602	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00025607	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00025602	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00025607	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00025604	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00025607	2 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00025602	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions