PCIDB

KNApSAcK Metabolite C00026150

Metabolite

KNApSAcK Entry

id C00026150
Name Tetrahydropalmatine / dl-Tetrahydropalmatine / (+/-)-Tetrahydropalmatine
CAS RN 2934-97-6
Standard InChI InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3
Standard InChI (Main Layer) InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 37

Link

ChEMBL

By standard InChI CHEMBL187892
By standard InChI Main Layer CHEMBL187892 CHEMBL487182 CHEMBL2334889

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
eudicotyledons 31
rosids 2
Magnoliophyta 1

Family

family name count
Menispermaceae 20
Papaveraceae 9
Rutaceae 1
Ranunculaceae 1
Annonaceae 1
Berberidaceae 1
Euphorbiaceae 1
Pieridae 1

List (39)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Annona cherimolia 13336 Annonaceae Magnoliophyta Viridiplantae
Chasmanthera dependens Hochst. 341015 Menispermaceae eudicotyledons Viridiplantae
Corydalis cava 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis intermedia 54425 Papaveraceae eudicotyledons Viridiplantae
Corydalis nobilis 38909 Papaveraceae eudicotyledons Viridiplantae
Corydalis ochroleuca 3463 Papaveraceae eudicotyledons Viridiplantae
Corydalis pallida 38903 Papaveraceae eudicotyledons Viridiplantae
Corydalis racemosa 54431 Papaveraceae eudicotyledons Viridiplantae
Corydalis solida 38914 Papaveraceae eudicotyledons Viridiplantae
Corydalis turtschaninowii 3463 Papaveraceae eudicotyledons Viridiplantae
Croton hemiargyreus 765397 Euphorbiaceae rosids Viridiplantae
Enantia chlorantha 320276 Pieridae Metazoa
Fibraurea chloroleuca Miers 527504 Menispermaceae eudicotyledons Viridiplantae
Fibraurea tinctoria Lour. 461588 Menispermaceae eudicotyledons Viridiplantae
Fumaria bastardii 1155334 Papaveraceae eudicotyledons Viridiplantae
Gloucium vitellinum Boiss and Buhse
Hyperbaena columbica (Eichl.) Miers 461589 Menispermaceae eudicotyledons Viridiplantae
Leontice leontopetalum Linn. 168832 Berberidaceae eudicotyledons Viridiplantae
Stephania bancroftii Bailey 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania brachyandra Diels 152368 Menispermaceae eudicotyledons Viridiplantae
Stephania delavayi Diels 216145 Menispermaceae eudicotyledons Viridiplantae
Stephania dicentrinifera H.S.Lo & M.Yang 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania dielsiana Wu 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania discflora Hand.-Mazz. 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania dolichopoda Diels 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania epigaea H.S.Lo 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania glabra (Roxb.) Miers 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania kuinanensis H.S.Lo & M.Yang 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania kwangsiensis H.S.Lo 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania lincangensis 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania macrantha 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania officinarum 147243 Menispermaceae eudicotyledons Viridiplantae
Stephania rotunda 461634 Menispermaceae eudicotyledons Viridiplantae
Stephania yunnanensis 152371 Menispermaceae eudicotyledons Viridiplantae
Stephanina aculeata
Stephanina bancroftii
Stephanina officinarum
Thalictrum minus 476039 Ranunculaceae eudicotyledons Viridiplantae
Zanthoxylum taediosum 67937 Rutaceae rosids Viridiplantae

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL487182 CHEMBL2334889 CHEMBL2343280 (2) CHEMBL2343284 (2)
0 / 0
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL487182 CHEMBL2334889 CHEMBL2343279 (2) CHEMBL2343283 (2)
2 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor CHEMBL187892 CHEMBL839610 (1)
1 / 0
P13726 Tissue factor Membrane receptor CHEMBL187892 CHEMBL487182 CHEMBL2319887 (2)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL487182 CHEMBL1941568 (1) CHEMBL1941569 (1)
1 / 1
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL487182 CHEMBL2334889 CHEMBL2343277 (2) CHEMBL2343281 (2)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL187892 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor CHEMBL487182 CHEMBL2334889 CHEMBL2343278 (2) CHEMBL2343282 (2)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#615363 Estrogen resistance; estrr P03372
#159900 Myoclonic dystonia P14416
#614674 Periodic fever, menstrual cycle-dependent P08908

KEGG DISEASE (2)

KEGG disease name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)