Croton hemiargyreus

• Index
• Plant Species
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Croton hemiargyreus
Genus	Croton
Family	Euphorbiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Croton hemiargyreus
Linked NCBI taxonomy ID	765397
Linked level	species

Family

Family in NCBI taxonomy	Euphorbiaceae
ID	3977

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001861	Glaucine / S-(+)-Glaucine / O,O-Dimethylisoboldine	CHEMBL36536 CHEMBL228082		14 / 8 / 6		No. 20	No. 4
C00001872	Isocorydine / (+)-Isocorydine / L-(+)-Isocorydine / (S)-(+)-Isocorydine	CHEMBL489525 CHEMBL1376826		14 / 7 / 10		No. 20	No. 4
C00025827	Corydine / Glaucentrin / (+)-Corydine / Glaucentrine	CHEMBL489524 CHEMBL2002847	C067341	1 / 0 / 0		No. 20	No. 4
C00027153	Norcorydine / (+)-Norcorydine	CHEMBL494053				No. 20	No. 4
C00027374	Hemiargyrine					No. 37	No. 4
C00001929	Xylopinine / O-Methylgovanine / S-(-)-Xylopinine / O,O-Dimethylgovadine	CHEMBL465824 CHEMBL2357282	C008672	1 / 0 / 0		No. 37	No. 4
C00026150	Tetrahydropalmatine / dl-Tetrahydropalmatine / (+/-)-Tetrahydropalmatine	CHEMBL187892 CHEMBL487182 CHEMBL2334889		8 / 5 / 2		No. 37	No. 4
C00027457	Oxoglaucine / O-Methylatheroline	CHEMBL470881	C111587	25 / 27 / 24		No. 74
C00001916	Salutaridine / (+)-Salutaridine	CHEMBL402782 CHEMBL404097	C009270	3 / 4 / 2		No. 426	No. 4
C00027443	Norsalutaridine					No. 426	No. 4
C00027154	Norlaudanosine / Tetrahydropapaverine / S-(-)-N-Norlaudanosine	CHEMBL160919				No. 4059

Human Protein / Gene in interactions

49 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001861 C00001872 C00027457	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00001872 C00001916 C00025827	0 / 0
O75496	Geminin	Unclassified protein	C00001861 C00001872 C00027457	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001872 C00026150 C00027457	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001861 C00001872	3 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001861 C00027457	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001872 C00027457	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00001861 C00001872	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001861 C00027457	4 / 3
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001872 C00027457	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001872 C00027457	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001861 C00027457	1 / 0
P43351	DNA repair protein RAD52 homolog	Unclassified protein	C00001861 C00001929	0 / 0
Q9GZR1	Sentrin-specific protease 6	Enzyme	C00001861	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00026150	2 / 0
Q14761	Protein tyrosine phosphatase receptor type C-associated protein	Enzyme	C00001861	0 / 0
Q9BQF6	Sentrin-specific protease 7	Enzyme	C00001861	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00027457	0 / 0
P42858	Huntingtin	Unclassified protein	C00027457	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00027457	2 / 0
P42574	Caspase-3	C14	C00001861	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00026150	1 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00027457	1 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00027457	1 / 2
Q96LD8	Sentrin-specific protease 8	Enzyme	C00001861	0 / 0
P00734	Prothrombin	S1A	C00001916	4 / 2
P13726	Tissue factor	Membrane receptor	C00026150	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00027457	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001872	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00027457	11 / 10
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00027457	2 / 2
Q92793	CREB-binding protein	Enzyme	C00027457	1 / 1
P03372	Estrogen receptor	NR3A1	C00026150	1 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00026150	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001916	0 / 0
P29466	Caspase-1	C14	C00027457	0 / 0
P06746	DNA polymerase beta	Enzyme	C00027457	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001861	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00027457	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00026150	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00026150	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00027457	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00027457	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00027457	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001872	1 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001872	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001872	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001872	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00027457	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions