Stephania dicentrinifera H.S.Lo & M.Yang

• Index
• Plant Species
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Stephania dicentrinifera H.S.Lo & M.Yang
Genus	Stephania
Family	Menispermaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Stephania
Linked NCBI taxonomy ID	147243
Linked level	genus

Family

Family in NCBI taxonomy	Menispermaceae
ID	3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00025313	Isotetrandrine / Isosinomenine A / O-Methylberbamine / O,O-Dimethylobamegine / O,O'-Dimethylobamegine / O,O-Dimethylstepholine / O,O'-Dimethylstepholine	CHEMBL176045 CHEMBL367260 CHEMBL445477 CHEMBL449690 CHEMBL504958 CHEMBL504757		26 / 23 / 48		No. 10	No. 4
C00025604	Cycleanine / (-)-Cycleanine	CHEMBL1711244 CHEMBL1983719	C037098	7 / 1 / 1		No. 10	No. 4
C00026150	Tetrahydropalmatine / dl-Tetrahydropalmatine / (+/-)-Tetrahydropalmatine	CHEMBL187892 CHEMBL487182 CHEMBL2334889		8 / 5 / 2		No. 37	No. 4
C00025761	8-Hydroxydehydroroemerine					No. 416

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	C00025313 C00025604	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00025313 C00025604	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00025313 C00025604	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00025313 C00026150	0 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00025313 C00025604	0 / 0
O75496	Geminin	Unclassified protein	C00025313 C00025604	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00025313 C00025604	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00025313	0 / 0
P08183	Multidrug resistance protein 1	drug	C00025313	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00025313	0 / 1
P14416	D(2) dopamine receptor	Dopamine receptor	C00026150	2 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00025313	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00025313	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00025313	2 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00026150	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00026150	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00025313	1 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00025313	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00025313	1 / 1
P13726	Tissue factor	Membrane receptor	C00026150	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00025313	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00025313	0 / 0
P03372	Estrogen receptor	NR3A1	C00026150	1 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00026150	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00025313	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00025313	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00025313	4 / 1
P04637	Cellular tumor antigen p53	Transcription Factor	C00025313	7 / 37
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00026150	1 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00025313	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00025313	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00025604	0 / 0
O00255	Menin	Unclassified protein	C00025313	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00025313	1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions