Species

KNApSAcK Entry

Organism name Leontice leontopetalum Linn.
Genus Leontice
Family Berberidaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Leontice
Linked NCBI taxonomy ID 168832
Linked level genus

Family

Family in NCBI taxonomy Berberidaceae
ID 41773

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00026150 External link 512 Tetrahydropalmatine
/ dl-Tetrahydropalmatine
/ (+/-)-Tetrahydropalmatine
CHEMBL187892
CHEMBL487182
CHEMBL2334889
8 / 5 / 2 No. 37 No. 4

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P21728 D(1A) dopamine receptor Dopamine receptor C00026150 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00026150 2 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00026150 1 / 0
P13726 Tissue factor Membrane receptor C00026150 0 / 0
P03372 Estrogen receptor NR3A1 C00026150 1 / 1
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00026150 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00026150 0 / 1
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00026150 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#615363 Estrogen resistance; estrr P03372
#159900 Myoclonic dystonia P14416
#614674 Periodic fever, menstrual cycle-dependent P08908

KEGG DISEASE (2)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)