Species

KNApSAcK Entry

Organism name Stephania bancroftii Bailey
Genus Stephania
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stephania
Linked NCBI taxonomy ID 147243
Linked level genus

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025235 External link 512 Crebanin
/ (-)-Crebanine
CHEMBL604339
CHEMBL1989287
C061009
1 / 0 / 0 No. 20 No. 4
C00025630 External link 512 Stephanine
/ l-Stephanine
/ (-)-Stephanine
/ (R)-(-)-Stephanine
CHEMBL601020
C054160
1 / 0 / 0 No. 20 No. 4
C00025294 External link 512 Ayuthianine
/ (-)-Ayuthianine
No. 20 No. 4
C00026150 External link 512 Tetrahydropalmatine
/ dl-Tetrahydropalmatine
/ (+/-)-Tetrahydropalmatine
CHEMBL187892
CHEMBL487182
CHEMBL2334889
8 / 5 / 2 No. 37 No. 4
C00025272 External link 512 Stepharine
/ (+)-Stepharine
CHEMBL463957
CHEMBL1975436
C009320
No. 688

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P24941 Cyclin-dependent kinase 2 Cdc2 C00025235 C00025630 0 / 0
P13726 Tissue factor Membrane receptor C00026150 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00026150 2 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00026150 1 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00026150 0 / 0
P03372 Estrogen receptor NR3A1 C00026150 1 / 1
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00026150 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00026150 0 / 1
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00026150 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#615363 Estrogen resistance; estrr P03372
#159900 Myoclonic dystonia P14416
#614674 Periodic fever, menstrual cycle-dependent P08908

KEGG DISEASE (2)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)