Species

KNApSAcK Entry

Organism name Corydalis turtschaninowii
Genus Corydalis
Family Fumariaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Corydalis
Linked NCBI taxonomy ID 3463
Linked level genus

Family

Family in NCBI taxonomy Papaveraceae
ID 3465

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00026150 External link 512 Tetrahydropalmatine
/ dl-Tetrahydropalmatine
/ (+/-)-Tetrahydropalmatine
CHEMBL187892
CHEMBL487182
CHEMBL2334889
8 / 5 / 2 No. 37 No. 4
C00026115 External link 512 Corydaline
/ d-Corydaline
/ (+)-Corydaline
CHEMBL2165401
C452799
No. 37 No. 4
C00001906 External link 512 Fumarin
/ Biflorine
/ Protopine
/ Fumarine
/ Corydinine
CHEMBL453019
C009093
5 / 5 / 4 2 / 0 No. 820 No. 4

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001906 C00026150 0 / 1
P03372 Estrogen receptor NR3A1 C00026150 1 / 1
P16473 Thyrotropin receptor Glycohormone receptor C00001906 3 / 2
P14416 D(2) dopamine receptor Dopamine receptor C00026150 2 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00026150 1 / 0
P13726 Tissue factor Membrane receptor C00026150 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00026150 0 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00026150 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001906 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001906 1 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00026150 1 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001906 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001906
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001906

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#159900 Myoclonic dystonia P14416
#614674 Periodic fever, menstrual cycle-dependent P08908

KEGG DISEASE (5)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)