Organism name | Stephania delavayi Diels |
---|---|
Genus | Stephania |
Family | Menispermaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Stephania delavayi |
---|---|
Linked NCBI taxonomy ID | 216145 |
Linked level | species |
Family in NCBI taxonomy | Menispermaceae |
---|---|
ID | 3455 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | eudicotyledons |
---|---|
ID | 71240 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00025313
![]() |
Isotetrandrine
/ Isosinomenine A / O-Methylberbamine / O,O-Dimethylobamegine / O,O'-Dimethylobamegine / O,O-Dimethylstepholine / O,O'-Dimethylstepholine |
CHEMBL176045
CHEMBL367260 CHEMBL445477 CHEMBL449690 CHEMBL504958 CHEMBL504757 |
26 / 23 / 48 | No. 10 | No. 4 |
![]() |
||
C00025310
![]() |
Homoaromoline
/ (+)-Homoaromoline / (+)-Thalrugosamine |
CHEMBL507220
CHEMBL503522 CHEMBL509855 CHEMBL1185978 |
No. 10 | No. 4 |
![]() |
|||
C00025604
![]() |
Cycleanine
/ (-)-Cycleanine |
CHEMBL1711244
CHEMBL1983719 |
C037098
|
7 / 1 / 1 | No. 10 | No. 4 |
![]() |
|
C00025607
![]() |
NSC 251699
/ L-Dicentrine / (-)-Dicentrine / (R)-(-)-Dicentrine |
CHEMBL464748
CHEMBL478754 |
15 / 20 / 16 | No. 20 | No. 4 |
![]() |
||
C00026150
![]() |
Tetrahydropalmatine
/ dl-Tetrahydropalmatine / (+/-)-Tetrahydropalmatine |
CHEMBL187892
CHEMBL487182 CHEMBL2334889 |
8 / 5 / 2 | No. 37 | No. 4 |
![]() |
||
C00025913
![]() |
Isostephodeline
/ (+)-Isostephodeline / (+)-14-Epierromangine |
No. 346 | No. 4 |
![]() |
||||
C00025097
![]() |
16-Oxodelavaine
|
No. 559 | No. 4 |
![]() |
||||
C00025105
![]() |
Delavaine
|
No. 2981 |
![]() |
|||||
C00025298
![]() |
Delavaine
/ (-)-Delavaine |
No. 2981 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
O75164 | Lysine-specific demethylase 4A | Enzyme | C00025313 C00025604 C00025607 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00025313 C00025604 C00025607 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00025313 C00025604 C00025607 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00025313 C00026150 | 0 / 1 |
Q99700 | Ataxin-2 | Unclassified protein | C00025313 C00025604 | 1 / 1 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00025313 C00025607 | 1 / 2 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00025313 C00025604 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00025313 C00025604 | 0 / 0 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00025313 C00025607 | 1 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00025313 C00025607 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00025313 | 1 / 0 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025607 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00025313 | 0 / 1 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00025607 | 1 / 0 |
P14416 | D(2) dopamine receptor | Dopamine receptor | C00026150 | 2 / 0 |
O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00025313 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00025607 | 11 / 10 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00025313 | 2 / 0 |
O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00025313 | 0 / 0 |
Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00026150 | 1 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00025607 | 0 / 0 |
P08183 | Multidrug resistance protein 1 | drug | C00025313 | 1 / 0 |
Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00025313 | 0 / 0 |
P06280 | Alpha-galactosidase A | Enzyme | C00025313 | 1 / 1 |
P13726 | Tissue factor | Membrane receptor | C00026150 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00025313 | 0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00025313 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00026150 | 1 / 1 |
P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00026150 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00025313 | 1 / 1 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | C00026150 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00025313 | 0 / 0 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00025313 | 4 / 1 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00025607 | 4 / 3 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00025607 | 0 / 0 |
P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00026150 | 1 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00025607 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00025313 | 1 / 1 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00025313 | 7 / 37 |
Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00025604 | 0 / 0 |
O00255 | Menin | Unclassified protein | C00025313 | 2 / 5 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00025607 | 2 / 1 |
P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00025607 | 0 / 0 |
OMIM | preferred title | UniProt |
---|---|---|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#103780 | Alcohol dependence |
P14416
|
#614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
P84022
Q14191 |
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#133239 | Esophageal cancer |
P04637
|
#615363 | Estrogen resistance; estrr |
P03372
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#211980 | Lung cancer |
P04637
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#159900 | Myoclonic dystonia |
P14416
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
#172700 | Pick disease of brain |
P10636
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#277700 | Werner syndrome; wrn |
Q14191
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00125 | Fabry disease |
P06280
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00296 | Defects in RecQ helicases |
Q14191
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |