Fibraurea chloroleuca Miers
Species
KNApSAcK Entry
| Organism name | Fibraurea chloroleuca Miers |
|---|---|
| Genus | Fibraurea |
| Family | Menispermaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Fibraurea chloroleuca |
|---|---|
| Linked NCBI taxonomy ID | 527504 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Menispermaceae |
|---|---|
| ID | 3455 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (8)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00026149
|
Corypalmine
/ Tetrahydrojatrorrhizine |
CHEMBL2334885
CHEMBL2334886 |
4 / 3 / 0 | No. 37 | No. 4 |
|
||
|
C00026150
|
Tetrahydropalmatine
/ dl-Tetrahydropalmatine / (+/-)-Tetrahydropalmatine |
CHEMBL187892
CHEMBL487182 CHEMBL2334889 |
8 / 5 / 2 | No. 37 | No. 4 |
|
||
|
C00026143
|
Govanine
/ Pseudocolumbamine |
CHEMBL1197451
|
No. 155 | No. 4 |
|
|||
|
C00026142
|
Palmatrubine
/ Palmaturbine |
No. 155 | No. 4 |
|
||||
|
C00026124
|
Dehydrocorydalmine
|
CHEMBL1618061
|
No. 155 | No. 4 |
|
|||
|
C00024667
|
Columbamine
/ Dehydroisocorypalmine |
CHEMBL400345
|
C055786
|
1 / 0 / 1 | 8 / 1 | No. 155 | No. 4 |
|
|
C00026111
|
Berberrubine
/ 9-Berberoline |
CHEMBL203135
CHEMBL2160119 |
5 / 10 / 6 | No. 155 | No. 4 |
|
||
|
C00026154
|
Thalifendine
|
CHEMBL1187148
|
C477156
|
No. 155 | No. 4 |
|
Human Protein / Gene in interactions
13 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00026149 C00026150 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00026149 C00026150 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00024667 C00026150 | 0 / 1 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00026149 C00026150 | 2 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00026149 C00026150 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00026150 | 1 / 1 |
| P13726 | Tissue factor | Membrane receptor | C00026150 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00026150 | 1 / 0 |
| Q09428 | ATP-binding cassette sub-family C member 8 | K | C00026111 | 5 / 3 |
| Q99700 | Ataxin-2 | Unclassified protein | C00026111 | 1 / 1 |
| Q14654 | ATP-sensitive inward rectifier potassium channel 11 | K | C00026111 | 3 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00026111 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00026111 | 2 / 1 |
8 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1003 | CDH5, 7B4, CD144 | cadherin 5, type 2 (vascular endothelium) |
C00024667
|
| 1021 | CDK6, PLSTIRE | cyclin-dependent kinase 6 (EC:2.7.11.22) |
C00024667
|
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00024667
|
| 2048 | EPHB2, CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5 | EPH receptor B2 (EC:2.7.10.1) |
C00024667
|
| 9500 | MAGED1, DLXIN-1, NRAGE | melanoma antigen family D, 1 |
C00024667
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00024667
|
| 64321 | SOX17, VUR3 | SRY (sex determining region Y)-box 17 |
C00024667
|
| 6774 | STAT3, APRF, HIES | signal transducer and activator of transcription 3 (acute-phase response factor) |
C00024667
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103780 | Alcohol dependence |
P14416
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #606176 | Diabetes mellitus, permanent neonatal; pndm |
Q09428
Q14654 |
| #610374 | Diabetes mellitus, transient neonatal, 2 |
Q09428
|
| #610582 | Diabetes mellitus, transient neonatal, 3 |
Q14654
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #256450 | Hyperinsulinemic hypoglycemia, familial, 1; hhf1 |
Q09428
|
| #601820 | Hyperinsulinemic hypoglycemia, familial, 2; hhf2 |
Q14654
|
| #602485 | Hyperinsulinemic hypoglycemia, familial, 3; hhf3 |
Q09428
|
| #240800 | Hypoglycemia, leucine-induced; lih |
Q09428
|
| #159900 | Myoclonic dystonia |
P14416
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #277700 | Werner syndrome; wrn |
Q14191
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00512 | Permanent neonatal diabetes mellitus (PNDM) |
Q09428
(related)
Q14654 (related) |
| H00513 | Transient neonatal diabetes mellitus (TNDM) |
Q09428
(related)
Q14654 (related) |
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
Q09428
(related)
Q14654 (related) |
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00409 | Type II diabetes mellitus |
Q14654
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|