PCIDB

KNApSAcK Metabolite C00026111

Metabolite

KNApSAcK Entry

id C00026111
Name Berberrubine / 9-Berberoline
CAS RN 17388-19-1
Standard InChI InChI=1S/C19H15NO4/c1-22-16-3-2-11-6-15-13-8-18-17(23-10-24-18)7-12(13)4-5-20(15)9-14(11)19(16)21/h2-3,6-9H,4-5,10H2,1H3/p+1
Standard InChI (Main Layer) InChI=1S/C19H15NO4/c1-22-16-3-2-11-6-15-13-8-18-17(23-10-24-18)7-12(13)4-5-20(15)9-14(11)19(16)21/h2-3,6-9H,4-5,10H2,1H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 155

Link

ChEMBL

By standard InChI CHEMBL203135
By standard InChI Main Layer CHEMBL203135 CHEMBL2160119

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL203135 CHEMBL2114784 (1)
1 / 1
Q09428 ATP-binding cassette sub-family C member 8 K CHEMBL203135 CHEMBL868372 (1) CHEMBL868377 (1)
5 / 3
Q14654 ATP-sensitive inward rectifier potassium channel 11 K CHEMBL203135 CHEMBL868377 (1)
3 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL203135 CHEMBL2114738 (1)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL203135 CHEMBL2114796 (1)
2 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc Q14191
#606176 Diabetes mellitus, permanent neonatal; pndm Q09428
Q14654
#610374 Diabetes mellitus, transient neonatal, 2 Q09428
#610582 Diabetes mellitus, transient neonatal, 3 Q14654
#256450 Hyperinsulinemic hypoglycemia, familial, 1; hhf1 Q09428
#601820 Hyperinsulinemic hypoglycemia, familial, 2; hhf2 Q14654
#602485 Hyperinsulinemic hypoglycemia, familial, 3; hhf3 Q09428
#240800 Hypoglycemia, leucine-induced; lih Q09428
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277700 Werner syndrome; wrn Q14191

KEGG DISEASE (6)

KEGG disease name UniProt
H00512 Permanent neonatal diabetes mellitus (PNDM) Q09428 (related)
Q14654 (related)
H00513 Transient neonatal diabetes mellitus (TNDM) Q09428 (related)
Q14654 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) Q09428 (related)
Q14654 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00409 Type II diabetes mellitus Q14654 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)