| Organism name | Berberis turcomanica | 
|---|---|
| Genus | Berberis | 
| Family | Berberidaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Berberis | 
|---|---|
| Linked NCBI taxonomy ID | 22774 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Berberidaceae | 
|---|---|
| ID | 41773 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | eudicotyledons | 
|---|---|
| ID | 71240 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00026063   | Aromoline / Thalicrine / (+)-Aromoline | CHEMBL504525 CHEMBL508781 | C066341 | 6 / 2 / 3 | No. 10 | No. 4 |   | |
| C00001817   | Berbamine / d-Berbamine / (+)-Berbamine | CHEMBL504323 CHEMBL507540 CHEMBL1198334 | C027870 | 4 / 3 / 4 | 9 / 1 | No. 10 | No. 4 |   | 
| C00001897   | Oxyacanthine | CHEMBL510022 CHEMBL509999 CHEMBL1983122 | C092646 | 5 / 4 / 1 | No. 10 | No. 4 |   | |
| C00001861   | Glaucine / S-(+)-Glaucine / O,O-Dimethylisoboldine | CHEMBL36536 CHEMBL228082 | 14 / 8 / 6 | No. 20 | No. 4 |   | ||
| C00027238   | Thalicmidine / Thaliporphine / (+)-Thaliporphine / (S)-O-Methylisoboldine | CHEMBL1394328 CHEMBL1397308 | C080702 | 20 / 26 / 56 | No. 20 | No. 4 |   | |
| C00025827   | Corydine / Glaucentrin / (+)-Corydine / Glaucentrine | CHEMBL489524 CHEMBL2002847 | C067341 | 1 / 0 / 0 | No. 20 | No. 4 |   | |
| C00026111   | Berberrubine / 9-Berberoline | CHEMBL203135 CHEMBL2160119 | 5 / 10 / 6 | No. 155 | No. 4 |   | ||
| C00001819   | Thalsine / Majarine / Berberine / Umbellatin | CHEMBL295124 | D001599 | 19 / 25 / 26 | 30 / 19 | No. 155 | No. 4 |   | 
| C00001874   | Neprotin / Neprotine / Yatrorizine / Jatrorrhizine | CHEMBL251055 | C055785 | 14 / 27 / 20 | 1 / 0 | No. 155 | No. 4 |   | 
| C00027159   | Depiline / Palmatine / Berbericinine / O,O-Dimethyldemethyleneberberine | CHEMBL206106 | C005413 | 8 / 13 / 13 | 8 / 0 | No. 155 | No. 4 |   | 
| C00024667   | Columbamine / Dehydroisocorypalmine | CHEMBL400345 | C055786 | 1 / 0 / 1 | 8 / 1 | No. 155 | No. 4 |   | 
| C00001810   | Armepavine / (-)-Armepavine / (R)-(-)-Armepavine | CHEMBL451722 CHEMBL1186477 CHEMBL1186510 | 7 / 5 / 3 | No. 345 | No. 4 |   | ||
| C00025997   | Berlambine / Oxyberberine / 8-Oxoberberine | CHEMBL11531 | No. 439 |   | ||||
| C00027499   | Turcomanine | No. 1137 |   | |||||
| C00027498   | Turcomanidine / 1-(3,4-Dihydroxybenzyl)-6,7-dimethoxyisoquinoline | No. 1137 |   | |||||
| C00027467   | Papavarine | CHEMBL19224 | 121 / 66 / 52 | No. 1165 | No. 4 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001817 C00001819 C00001874 C00024667 C00026063 C00027159 C00027238 C00027467 | 0 / 1 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001810 C00001819 C00001861 C00027238 C00027467 | 0 / 0 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001819 C00026063 C00027159 C00027238 C00027467 | 1 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001819 C00026063 C00027159 C00027238 C00027467 | 1 / 1 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001810 C00001861 C00001874 C00027238 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001819 C00001861 C00001874 C00027238 | 4 / 3 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001819 C00026063 C00027159 C00027467 | 0 / 0 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001810 C00001817 C00001861 C00027238 | 3 / 3 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001819 C00026063 C00027159 C00027467 | 0 / 1 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00001874 C00027159 C00027467 | 11 / 10 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00001819 C00001874 C00027467 | 4 / 1 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001810 C00001874 C00027467 | 0 / 0 | 
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001819 C00027159 C00027467 | 0 / 0 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001810 C00001874 C00026111 | 0 / 0 | 
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001810 C00027238 C00027467 | 0 / 0 | 
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00001861 C00001874 C00001897 | 0 / 0 | 
| P29466 | Caspase-1 | C14 | C00027238 C00027467 | 0 / 0 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001819 C00027238 | 1 / 2 | 
| O00255 | Menin | Unclassified protein | C00001819 C00027238 | 2 / 5 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00027238 C00027467 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00001897 C00026111 | 1 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001861 C00001874 | 0 / 0 | 
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001819 C00027467 | 2 / 2 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00027238 C00027467 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001810 C00001897 | 2 / 0 | 
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001817 C00026063 | 0 / 0 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001861 C00001874 | 1 / 0 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001819 C00027467 | 3 / 2 | 
| P54750 | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | PDE_1A | C00001817 C00027467 | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00027467 | 0 / 1 | 
| P00918 | Carbonic anhydrase 2 | Lyase | C00027467 | 1 / 2 | 
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 1 | 
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00027467 | 1 / 1 | 
| P25021 | Histamine H2 receptor | Histamine receptor | C00027467 | 0 / 0 | 
| P35367 | Histamine H1 receptor | Histamine receptor | C00027467 | 0 / 0 | 
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00027467 | 1 / 0 | 
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00027467 | 0 / 0 | 
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 | 
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00027238 | 3 / 1 | 
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00027467 | 0 / 0 | 
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025827 | 0 / 0 | 
| P06241 | Tyrosine-protein kinase Fyn | Src | C00027467 | 0 / 0 | 
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00027467 | 0 / 0 | 
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00027467 | 0 / 0 | 
| P54132 | Bloom syndrome protein | Enzyme | C00027238 | 1 / 2 | 
| Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00001861 | 0 / 0 | 
| Q9BQF6 | Sentrin-specific protease 7 | Enzyme | C00001861 | 0 / 0 | 
| Q9GZR1 | Sentrin-specific protease 6 | Enzyme | C00001861 | 0 / 0 | 
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00027467 | 1 / 8 | 
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00027467 | 2 / 0 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00027467 | 0 / 0 | 
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00027467 | 0 / 0 | 
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00027467 | 0 / 0 | 
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00027467 | 0 / 0 | 
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00027467 | 0 / 0 | 
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00027467 | 0 / 0 | 
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00027467 | 1 / 1 | 
| Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001861 | 0 / 0 | 
| P04062 | Glucosylceramidase | Enzyme | C00001874 | 6 / 4 | 
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00027467 | 0 / 0 | 
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00027467 | 1 / 0 | 
| P06746 | DNA polymerase beta | Enzyme | C00001874 | 0 / 0 | 
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00027467 | 2 / 2 | 
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00027467 | 0 / 0 | 
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00027467 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00001874 | 0 / 0 | 
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00027467 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00001861 | 0 / 0 | 
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00027467 | 0 / 0 | 
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00027467 | 0 / 0 | 
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 | 
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00027467 | 0 / 0 | 
| P30988 | Calcitonin receptor | Calcitonin receptor | C00027467 | 0 / 0 | 
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00027467 | 1 / 0 | 
| P41143 | Delta-type opioid receptor | Opioid receptor | C00027467 | 0 / 0 | 
| Q92731 | Estrogen receptor beta | NR3A2 | C00027467 | 0 / 1 | 
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00027467 | 0 / 0 | 
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00027467 | 0 / 0 | 
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00027467 | 0 / 0 | 
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00027467 | 1 / 0 | 
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00027467 | 0 / 0 | 
| P08311 | Cathepsin G | S1A | C00027467 | 0 / 0 | 
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00027467 | 1 / 0 | 
| P03956 | Interstitial collagenase | M10A | C00027467 | 0 / 1 | 
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00027467 | 0 / 0 | 
| Q9Y233 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | PDE_10A | C00027467 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00027467 | 0 / 0 | 
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00001819 | 1 / 0 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00027159 | 0 / 0 | 
| P42574 | Caspase-3 | C14 | C00001861 | 0 / 0 | 
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00027467 | 2 / 0 | 
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00027467 | 0 / 0 | 
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00027467 | 0 / 0 | 
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00027467 | 2 / 0 | 
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00027467 | 5 / 9 | 
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00027467 | 1 / 0 | 
| P21452 | Substance-K receptor | Neurokinin receptor | C00027467 | 0 / 0 | 
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00027467 | 0 / 0 | 
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00027467 | 3 / 0 | 
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00027467 | 0 / 0 | 
| P06280 | Alpha-galactosidase A | Enzyme | C00027238 | 1 / 1 | 
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00027467 | 2 / 0 | 
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00027467 | 1 / 0 | 
| Q92793 | CREB-binding protein | Enzyme | C00027467 | 1 / 1 | 
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00027467 | 2 / 1 | 
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00027467 | 0 / 0 | 
| P08246 | Neutrophil elastase | S1A | C00027467 | 2 / 1 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00027238 | 2 / 2 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001861 | 0 / 0 | 
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00027467 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00027467 | 1 / 1 | 
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00027467 | 1 / 0 | 
| P22303 | Acetylcholinesterase | Hydrolase | C00027467 | 1 / 0 | 
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00027467 | 0 / 0 | 
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00027467 | 0 / 0 | 
| P35372 | Mu-type opioid receptor | Opioid receptor | C00027467 | 0 / 0 | 
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00027467 | 0 / 0 | 
| P25103 | Substance-P receptor | Neurokinin receptor | C00027467 | 0 / 0 | 
| P25105 | Platelet-activating factor receptor | PAF receptor | C00027467 | 0 / 0 | 
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00027467 | 0 / 0 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00027467 | 0 / 0 | 
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00027467 | 0 / 0 | 
| Q09428 | ATP-binding cassette sub-family C member 8 | K | C00026111 | 5 / 3 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00027467 | 0 / 3 | 
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00027467 | 0 / 0 | 
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00027467 | 0 / 0 | 
| P14780 | Matrix metalloproteinase-9 | M10A | C00027467 | 2 / 2 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001897 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00027238 | 0 / 0 | 
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00027467 | 0 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00027467 | 0 / 0 | 
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00027467 | 1 / 1 | 
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 | 
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00027467 | 0 / 0 | 
| Q14432 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | PDE_3A | C00027467 | 0 / 0 | 
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00027467 | 0 / 0 | 
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00027467 | 1 / 1 | 
| P06239 | Tyrosine-protein kinase Lck | Src | C00027467 | 0 / 1 | 
| O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | PDE_2A | C00027467 | 0 / 0 | 
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00027467 | 0 / 0 | 
| O14746 | Telomerase reverse transcriptase | Enzyme | C00001819 | 5 / 5 | 
| P17252 | Protein kinase C alpha type | Alpha | C00027467 | 0 / 0 | 
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00001819 | 0 / 0 | 
| P40225 | Thrombopoietin | Unclassified protein | C00027467 | 1 / 1 | 
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00001819 | 1 / 0 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001897 | 1 / 0 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00001874 | 1 / 1 | 
| Q13370 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | PDE_3B | C00027467 | 0 / 0 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001819 | 0 / 1 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001819 | 1 / 4 | 
| Q14654 | ATP-sensitive inward rectifier potassium channel 11 | K | C00026111 | 3 / 4 | 
| Q14123 | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | PDE_1C | C00027467 | 0 / 0 | 
| Q01064 | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | PDE_1B | C00027467 | 0 / 0 | 
| P27815 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | PDE_4A | C00027467 | 0 / 0 | 
| Q08499 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | PDE_4D | C00027467 | 1 / 0 | 
| Q07343 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | PDE_4B | C00027467 | 0 / 0 | 
| Q08493 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C | PDE_4C | C00027467 | 0 / 0 | 
| Q9NY46 | Sodium channel protein type 3 subunit alpha | SCN alpha, NaV1.x | C00027467 | 0 / 0 | 
| Q99250 | Sodium channel protein type 2 subunit alpha | SCN alpha, NaV1.x | C00027467 | 2 / 2 | 
| P35498 | Sodium channel protein type 1 subunit alpha | SCN alpha, NaV1.x | C00027467 | 3 / 2 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00027238 | 7 / 37 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00026111 | 2 / 1 | 
| P55210 | Caspase-7 | C14 | C00027238 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 | C00001817
                          C00001819
                          C00001874
                          C00027159 | 
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 | C00001817
                          C00001819 | 
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) | C00001819
                          C00024667 | 
| 1021 | CDK6, PLSTIRE | cyclin-dependent kinase 6 (EC:2.7.11.22) | C00001819
                          C00024667 | 
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 | C00001819
                          C00027159 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00001817
                          C00001819 | 
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 | C00001819
                          C00027159 | 
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 | C00001817
                          C00001819 | 
| 6774 | STAT3, APRF, HIES | signal transducer and activator of transcription 3 (acute-phase response factor) | C00024667 | 
| 637 | BID, FP497 | BH3 interacting domain death agonist | C00001817 | 
| 3570 | IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80 | interleukin 6 receptor | C00027159 | 
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 | C00027159 | 
| 1147 | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) | C00001817 | 
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | C00001817 | 
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A | C00001817 | 
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) | C00001817 | 
| 1003 | CDH5, 7B4, CD144 | cadherin 5, type 2 (vascular endothelium) | C00024667 | 
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 | C00027159 | 
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) | C00024667 | 
| 2048 | EPHB2, CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5 | EPH receptor B2 (EC:2.7.10.1) | C00024667 | 
| 9500 | MAGED1, DLXIN-1, NRAGE | melanoma antigen family D, 1 | C00024667 | 
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 | C00027159 | 
| 64321 | SOX17, VUR3 | SRY (sex determining region Y)-box 17 | C00024667 | 
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A | C00027159 | 
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor | C00001819 | 
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00001819 | 
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 | C00001819 | 
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | C00001819 | 
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | C00001819 | 
| 894 | CCND2, KIAK0002 | cyclin D2 | C00001819 | 
| 898 | CCNE1, CCNE | cyclin E1 | C00001819 | 
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) | C00001819 | 
| 1019 | CDK4, CMM3, PSK-J3 | cyclin-dependent kinase 4 (EC:2.7.11.22) | C00001819 | 
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | C00001819 | 
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | C00001819 | 
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic | C00001819 | 
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00001819 | 
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor | C00001819 | 
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) | C00001819 | 
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta | C00001819 | 
| 5027 | P2RX7, P2X7 | purinergic receptor P2X, ligand-gated ion channel, 7 | C00001819 | 
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | C00001819 | 
| 6476 | SI | sucrase-isomaltase (alpha-glucosidase) (EC:3.2.1.10 3.2.1.48) | C00001819 | 
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor | C00001819 | 
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 | C00001819 | 
| 7185 | TRAF1, EBI6, MGC:10353 | TNF receptor-associated factor 1 | C00001819 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism | P20309 | 
| #614613 | Acrodysostosis 2, with or without hormone resistance; acrdys2 | Q08499 | 
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #103780 | Alcohol dependence | P08172 P14416 P31645 | 
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 | Q99720 | 
| #609135 | Aplastic anemia | O14746 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #210900 | Bloom syndrome; blm | P54132 | 
| #602025 | Body mass index quantitative trait locus 9; bmiq9 | P41968 | 
| #300615 | Brunner syndrome | P21397 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #114500 | Colorectal cancer; crc | P18054 P84022 Q14191 | 
| #162800 | Cyclic neutropenia | P08246 | 
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 | P51681 | 
| #606176 | Diabetes mellitus, permanent neonatal; pndm | Q09428 Q14654 | 
| #610374 | Diabetes mellitus, transient neonatal, 2 | Q09428 | 
| #610582 | Diabetes mellitus, transient neonatal, 3 | Q14654 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #607208 | Dravet syndrome | P35498 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #613989 | Dyskeratosis congenita, autosomal dominant, 2; dkca2 | O14746 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #613721 | Epileptic encephalopathy, early infantile, 11; eiee11 | Q99250 | 
| #133239 | Esophageal cancer | P04637 P18054 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #301500 | Fabry disease | P06280 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #613659 | Gastric cancer | P04626 | 
| #137215 | Gastric cancer, hereditary diffuse; hdgc | P04626 | 
| #608013 | Gaucher disease, perinatal lethal | P04062 | 
| #230800 | Gaucher disease, type i | P04062 | 
| #230900 | Gaucher disease, type ii | P04062 | 
| #231000 | Gaucher disease, type iii | P04062 | 
| #231005 | Gaucher disease, type iiic | P04062 | 
| #604403 | Generalized epilepsy with febrile seizures plus, type 2; gefsp2 | P35498 | 
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd | P24557 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 P04626 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #609423 | Human immunodeficiency virus type 1, susceptibility to | P41597 P51681 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #237450 | Hyperbilirubinemia, rotor type; hblrr | Q9NPD5 Q9Y6L6 | 
| #256450 | Hyperinsulinemic hypoglycemia, familial, 1; hhf1 | Q09428 | 
| #601820 | Hyperinsulinemic hypoglycemia, familial, 2; hhf2 | Q14654 | 
| #602485 | Hyperinsulinemic hypoglycemia, familial, 3; hhf3 | Q09428 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #240800 | Hypoglycemia, leucine-induced; lih | Q09428 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #603932 | Intervertebral disc disease; idd | P14780 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #613688 | Long qt syndrome 2; lqt2 | Q12809 | 
| #211980 | Lung cancer | P00533 P04626 P04637 | 
| #608516 | Major depressive disorder; mdd | P08172 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #615134 | Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 | O14746 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| %300852 | Mental retardation, x-linked 88; mrx88 | P50052 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #613073 | Metaphyseal anadysplasia 2; mandp2 | P14780 | 
| #609634 | Migraine, familial hemiplegic, 3; fhm3 | P35498 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #126200 | Multiple sclerosis, susceptibility to; ms | P08575 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #159900 | Myoclonic dystonia | P14416 | 
| #160900 | Myotonic dystrophy 1; dm1 | Q9NR56 | 
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 | P08246 | 
| #257200 | Niemann-pick disease, type a | P17405 | 
| #607616 | Niemann-pick disease, type b | P17405 | 
| #601665 | Obesity | P32245 | 
| #164230 | Obsessive-compulsive disorder; ocd | P31645 | 
| #604715 | Orthostatic intolerance | P23975 | 
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 | P00918 | 
| #167000 | Ovarian cancer | P04626 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #168600 | Parkinson disease, late-onset; pd | P04062 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #613135 | Parkinsonism-dystonia, infantile; pkdys | Q01959 | 
| #172700 | Pick disease of brain | P10636 | 
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | Q01196 | 
| #614742 | Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 | O14746 | 
| #178500 | Pulmonary fibrosis, idiopathic; ipf | O14746 | 
| #607276 | Resting heart rate, variation in | P08588 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #180849 | Rubinstein-taybi syndrome 1; rsts1 | Q92793 | 
| #607745 | Seizures, benign familial infantile, 3; bfis3 | Q99250 | 
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive | P08575 | 
| #609620 | Short qt syndrome 1; sqt1 | Q12809 | 
| #253300 | Spinal muscular atrophy, type i; sma1 | Q16637 | 
| #253550 | Spinal muscular atrophy, type ii; sma2 | Q16637 | 
| #253400 | Spinal muscular atrophy, type iii; sma3 | Q16637 | 
| #271150 | Spinal muscular atrophy, type iv; sma4 | Q16637 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #187950 | Thrombocythemia 1; thcyt1 | P40225 | 
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | P10828 | 
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | P10828 | 
| #145650 | Thyroid hormone resistance, selective pituitary; prth | P10828 | 
| #190300 | Tremor, hereditary essential, 1; etm1 | P35462 | 
| #277700 | Werner syndrome; wrn | Q14191 | 
| #610379 | West nile virus, susceptibility to | P51681 | 
| #112100 | Yt blood group antigen | P22303 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) P04637 (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00764 | Cri du chat syndrome | O14746
                            (related) | 
| H01132 | Aplastic anemia (AA) | O14746
                            (related) | 
| H01299 | Idiopathic pulmonary fibrosis | O14746
                            (related) | 
| H00022 | Bladder cancer | O14746
                            (marker) P00533 (related) P04626 (related) P04637 (related) | 
| H00024 | Prostate cancer | O14746
                            (marker) | 
| H00016 | Oral cancer | P00533
                            (related) P00533 (marker) P04637 (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P00533
                            (related) P04637 (related) P04637 (marker) P35354 (related) | 
| H00018 | Gastric cancer | P00533
                            (related) P04626 (related) P04637 (related) | 
| H00028 | Choriocarcinoma | P00533
                            (related) P03956 (related) P04626 (related) P04637 (related) | 
| H00030 | Cervical cancer | P00533
                            (related) P04626 (related) | 
| H00042 | Glioma | P00533
                            (related) P00533 (marker) P04637 (related) P04637 (marker) | 
| H00055 | Laryngeal cancer | P00533
                            (related) P00533 (marker) P04637 (related) P04637 (marker) | 
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) | P00918
                            (related) | 
| H00436 | Osteopetrosis | P00918
                            (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00026 | Endometrial Cancer | P03372
                            (marker) P04626 (related) P04637 (related) Q92731 (marker) | 
| H00066 | Lewy body dementia (LBD) | P04062
                            (related) | 
| H00126 | Gaucher disease | P04062
                            (related) | 
| H00426 | Defects in the degradation of ganglioside | P04062
                            (related) | 
| H00810 | Progressive myoclonic epilepsy (PME) | P04062
                            (related) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P04150
                            (related) | 
| H00019 | Pancreatic cancer | P04626
                            (related) P04637 (related) P04637 (marker) | 
| H00027 | Ovarian cancer | P04626
                            (related) P04637 (related) | 
| H00031 | Breast cancer | P04626
                            (related) P04626 (marker) P04637 (related) | 
| H00046 | Cholangiocarcinoma | P04626
                            (related) P04637 (related) P35354 (related) | 
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) Q01196 (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) P14780 (related) P35354 (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) P08684 (marker) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H00093 | Combined immunodeficiencies (CIDs) | P06239
                            (related) | 
| H00125 | Fabry disease | P06280
                            (related) | 
| H00079 | Asthma | P07550
                            (related) | 
| H00100 | Neutropenic disorders | P08246
                            (related) | 
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) | P08575
                            (related) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00249 | Thyroid hormone resistance syndrome | P10828
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00479 | Metaphyseal dysplasias | P14780
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P16473
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H00137 | Niemann-Pick disease (NPD) typeA and B | P17405
                            (related) | 
| H00424 | Defects in the degradation of sphingomyelin | P17405
                            (related) | 
| H00548 | Brunner syndrome | P21397
                            (related) | 
| H01031 | Orthostatic intolerance (OI) | P23975
                            (related) | 
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) | P24557
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00775 | Familial or sporadic hemiplegic migraine | P35498
                            (related) | 
| H00783 | Febrile seizures | P35498
                            (related) | 
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) | P40225
                            (marker) | 
| H00480 | Non-syndromic X-linked mental retardation | P50052
                            (related) Q99714 (related) | 
| H00094 | DNA repair defects | P54132
                            (related) | 
| H00296 | Defects in RecQ helicases | P54132
                            (related) Q14191 (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q01196
                            (related) Q01196 (marker) Q03164 (related) Q03164 (marker) | 
| H00003 | Acute myeloid leukemia (AML) | Q01196
                            (related) Q01196 (marker) Q13951 (marker) | 
| H00978 | Thrombocytopenia (THC) | Q01196
                            (related) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00512 | Permanent neonatal diabetes mellitus (PNDM) | Q09428
                            (related) Q14654 (related) | 
| H00513 | Transient neonatal diabetes mellitus (TNDM) | Q09428
                            (related) Q14654 (related) | 
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) | Q09428
                            (related) Q14654 (related) | 
| H00720 | Long QT syndrome | Q12809
                            (related) | 
| H00725 | Short QT syndrome | Q12809
                            (related) | 
| H00409 | Type II diabetes mellitus | Q14654
                            (related) | 
| H00455 | Spinal muscular atrophy (SMA) | Q16637
                            (related) | 
| H00504 | Rubinstein-Taybi syndrome | Q92793
                            (related) | 
| H00606 | Early infantile epileptic encephalopathy | Q99250
                            (related) | 
| H00806 | Benign familial neonatal and infantile epilepsies | Q99250
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D015473 | Leukemia, Promyelocytic, Acute | C00001817 | 
| D009361 | Neoplasm Invasiveness | C00024667 | 
| D000647 | Amnesia | C00001819 | 
| D001862 | Bone Resorption | C00001819 | 
| D002471 | Cell Transformation, Neoplastic | C00001819 | 
| D003556 | Cystitis | C00001819 | 
| D003920 | Diabetes Mellitus | C00001819 | 
| D003921 | Diabetes Mellitus, Experimental | C00001819 | 
| D003924 | Diabetes Mellitus, Type 2 | C00001819 | 
| D004487 | Edema | C00001819 | 
| D006470 | Hemorrhage | C00001819 | 
| D006937 | Hypercholesterolemia | C00001819 | 
| D006943 | Hyperglycemia | C00001819 | 
| D006949 | Hyperlipidemias | C00001819 | 
| D006973 | Hypertension | C00001819 | 
| D007077 | Ileal Diseases | C00001819 | 
| D007333 | Insulin Resistance | C00001819 | 
| D007410 | Intestinal Diseases | C00001819 | 
| D009369 | Neoplasms | C00001819 | 
| D010190 | Pancreatic Neoplasms | C00001819 | 
| D011471 | Prostatic Neoplasms | C00001819 |