Organism name | Stephania mashanica H.S.Lo.et.B.N.Chang |
---|---|
Genus | Stephania |
Family | Menispermaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Stephania |
---|---|
Linked NCBI taxonomy ID | 147243 |
Linked level | genus |
Family in NCBI taxonomy | Menispermaceae |
---|---|
ID | 3455 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | eudicotyledons |
---|---|
ID | 71240 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00025607 |
NSC 251699
/ L-Dicentrine / (-)-Dicentrine / (R)-(-)-Dicentrine |
CHEMBL464748
CHEMBL478754 |
15 / 20 / 16 | No. 20 | No. 4 | |||
C00025632 |
Isocorypalmine
/ (-)-Isocorypalmine / Tetrahydrocolumbamine / O10-Methylstepholidine |
CHEMBL2334891
CHEMBL2334892 |
4 / 3 / 0 | No. 37 | No. 4 | |||
C00025849 |
Dicentrinone
/ Oxodicentrine |
CHEMBL463284
|
1 / 0 / 0 | No. 74 | ||||
C00025629 |
Sinoacutine
/ (-)-Sinoacutine / (-)-Salutaridine |
CHEMBL402782
CHEMBL404097 |
3 / 4 / 2 | No. 426 | No. 4 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025607 C00025629 | 0 / 0 |
P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00025632 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00025607 | 11 / 10 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | C00025632 | 0 / 0 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00025607 | 1 / 0 |
P11387 | DNA topoisomerase 1 | Isomerase | C00025849 | 0 / 0 |
P14416 | D(2) dopamine receptor | Dopamine receptor | C00025632 | 2 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00025607 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00025607 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00025607 | 1 / 2 |
P00734 | Prothrombin | S1A | C00025629 | 4 / 2 |
P06746 | DNA polymerase beta | Enzyme | C00025607 | 0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00025629 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00025607 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00025607 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00025607 | 4 / 3 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00025607 | 0 / 0 |
P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00025632 | 1 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00025607 | 0 / 0 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00025607 | 1 / 0 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00025607 | 2 / 1 |
P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00025607 | 0 / 0 |
OMIM | preferred title | UniProt |
---|---|---|
#103780 | Alcohol dependence |
P14416
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
Q14191
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#159900 | Myoclonic dystonia |
P14416
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
#172700 | Pick disease of brain |
P10636
|
#614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
#613679 | Prothrombin deficiency, congenital |
P00734
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#601367 | Stroke, ischemic |
P00734
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
#277700 | Werner syndrome; wrn |
Q14191
|
KEGG | name | UniProt |
---|---|---|
H00223 | Inherited thrombophilia |
P00734
(related)
|
H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00296 | Defects in RecQ helicases |
Q14191
(related)
|