Species

KNApSAcK Entry

Organism name Stephania elegans Hook.& Thoms.
Genus Stephania
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stephania
Linked NCBI taxonomy ID 147243
Linked level genus

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001870 External link 512 Isobebeerin
/ Isobebeerine
/ Isochondodendrine
CHEMBL509310
CHEMBL1169628
No. 10 No. 4
C00025266 External link 512 Isosinomenin A
/ Isotetrandrine
/ Isosinomenine A
/ O-Methylberbamine
/ (+)-Isotetrandrine
/ O,O-Dimethylobamegine
/ O,O'-Dimethylobamegine
/ O,O-Dimethylstepholine
/ O,O'-Dimethylstepholine
No. 10 No. 4
C00026120 External link 512 Cyclanoline
/ (-)-Cissamine
/ alpha-Cyclanoline
CHEMBL2008127
C060801
No. 234
C00026137 External link 512 N-Methylcorydalmine
No. 234
C00025629 External link 512 Sinoacutine
/ (-)-Sinoacutine
/ (-)-Salutaridine
CHEMBL402782
CHEMBL404097
3 / 4 / 2 No. 426 No. 4
C00025910 External link 512 Isosinoacutine
No. 426 No. 4
C00025102 External link 512 Aknadinine
/ 4-Demethylhasubanonine
/ O4-Demethylhasubanonine
CHEMBL1098359
C099121
3 / 0 / 0 No. 559 No. 4
C00025106 External link 512 Epihernandolinol
No. 559 No. 4

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35372 Mu-type opioid receptor Opioid receptor C00025102 C00025629 0 / 0
P41143 Delta-type opioid receptor Opioid receptor C00025102 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00025102 0 / 0
P00734 Prothrombin S1A C00025629 4 / 2
P24941 Cyclin-dependent kinase 2 Cdc2 C00025629 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (2)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)