| class name | count |
|---|---|
| eudicotyledons | 46 |
| rosids | 3 |
| Magnoliophyta | 2 |
| class name | count |
|---|---|
| Menispermaceae | 25 |
| Papaveraceae | 18 |
| Rutaceae | 3 |
| Annonaceae | 2 |
| Ranunculaceae | 2 |
| Berberidaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00025232
|
(-)-cis-Xylopinine N-oxide
|
|
||||
|
C00025256
|
(-)-trans-Xylopinine N-oxide
|
|
||||
|
C00025295
|
beta-Cyclanoline
/ (-)-b-Cyclanoline |
CHEMBL2008127
|
|
|||
|
C00025359
|
Cissamine
/ Ciclanoline / Cyclanoline / (-)-Cissamine / l-Cyclanoline / (-)-Cyclanoline / alpha-Cyclanoline |
CHEMBL2008127
|
C060801
|
|
||
|
C00025617
|
N,O-Dimethylthaicanine
/ (-)-N,O-Dimethylthaicanine |
|
||||
|
C00025620
|
(-)-N-Methylthaicanine
|
|
||||
|
C00025798
|
Cissamine
|
CHEMBL2008127
|
C060801
|
|
||
|
C00026083
|
(-)-(alpha)-Stylopine methiodide
|
|
||||
|
C00026085
|
(-)-alpha-canadine methohydroxide
|
CHEMBL441356
|
4 / 7 / 4 |
|
||
|
C00026086
|
beta-Stylopine methiodide
/ (-)-beta-N-Methylstylopinium |
|
||||
|
C00026089
|
(-)-Cyclanoline iodide
|
CHEMBL2008127
|
|
|||
|
C00026110
|
alpha-Stylopine methohydroxide
/ cis-N-Methylstylopinium hydroxide / (-)-alpha-Stylopine methohydroxide |
|
||||
|
C00026116
|
Corynoxidine
|
CHEMBL1417461
|
1 / 0 / 0 |
|
||
|
C00026120
|
Cyclanoline
/ (-)-Cissamine / alpha-Cyclanoline |
CHEMBL2008127
|
C060801
|
|
||
|
C00026135
|
N-Methylcanadine
/ (-)-cis-N-Methylcanadine / (-)-alpha-N-Methylcanadine / N-Methyl-(-)-alpha-canadinium |
CHEMBL441356
|
4 / 7 / 4 |
|
||
|
C00026136
|
N-Methylcanadine hydroxide
|
CHEMBL441356
|
4 / 7 / 4 |
|
||
|
C00026137
|
N-Methylcorydalmine
|
|
||||
|
C00026139
|
N-Methylsinactine
|
|
||||
|
C00026148
|
Steponine
/ (-)-Steponine |
|
||||
|
C00027160
|
Phellodendrine
|
C079418
|
|
|||
|
C00027325
|
cis-N-Methyltetrahydropalmatine
/ (-)-N-Methyltetrahydropalmatine |
CHEMBL516562
|
|
|||
|
C00027431
|
N-Methyltetrahydrocolumbamine
/ (-)-N-Methyltetrahydrocolumbamine |
|
||||
|
C00027597
|
trans-N-Methylcorypalmine
|
CHEMBL1417461
|
1 / 0 / 0 |
|
||
|
C00027900
|
Argemonine-N-oxide
/ Argemonine, 13-oxide |
|
||||
|
C00028059
|
cis-Caseadine N-oxide
/ cis-(-)-Caseadine N-oxide |
|
||||
|
C00032838
|
cis-N-Methylcapaurine
/ 9-O-Methylstecepharine |
|
||||
|
C00033389
|
Stecepharine
/ (-)-Stecepharine |
|
||||
|
C00039036
|
Discretine N-oxide
/ (-)-Discretine N-oxide |
CHEMBL456615
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q09428 | ATP-binding cassette sub-family C member 8 | K | C00026085 C00026135 C00026136 | 5 / 3 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00026085 C00026135 C00026136 | 0 / 0 |
| Q14654 | ATP-sensitive inward rectifier potassium channel 11 | K | C00026085 C00026135 C00026136 | 3 / 4 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00026085 C00026135 C00026136 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00026116 C00027597 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #606176 | Diabetes mellitus, permanent neonatal; pndm |
Q09428
Q14654 |
| #610374 | Diabetes mellitus, transient neonatal, 2 |
Q09428
|
| #610582 | Diabetes mellitus, transient neonatal, 3 |
Q14654
|
| #256450 | Hyperinsulinemic hypoglycemia, familial, 1; hhf1 |
Q09428
|
| #601820 | Hyperinsulinemic hypoglycemia, familial, 2; hhf2 |
Q14654
|
| #602485 | Hyperinsulinemic hypoglycemia, familial, 3; hhf3 |
Q09428
|
| #240800 | Hypoglycemia, leucine-induced; lih |
Q09428
|
| KEGG | name | UniProt |
|---|---|---|
| H00512 | Permanent neonatal diabetes mellitus (PNDM) |
Q09428
(related)
Q14654 (related) |
| H00513 | Transient neonatal diabetes mellitus (TNDM) |
Q09428
(related)
Q14654 (related) |
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
Q09428
(related)
Q14654 (related) |
| H00409 | Type II diabetes mellitus |
Q14654
(related)
|