PCIDB

KNApSAcK Metabolite C00026085

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00026085
Name	(-)-alpha-canadine methohydroxide
CAS RN	51261-74-6
Standard InChI	InChI=1S/C21H24NO4/c1-22-7-6-14-9-19-20(26-12-25-19)10-15(14)17(22)8-13-4-5-18(23-2)21(24-3)16(13)11-22/h4-5,9-10,17H,6-8,11-12H2,1-3H3/q+1/t17-,22-/m0/s1
Standard InChI (Main Layer)	InChI=1S/C21H24NO4/c1-22-7-6-14-9-19-20(26-12-25-19)10-15(14)17(22)8-13-4-5-18(23-2)21(24-3)16(13)11-22/h4-5,9-10,17H,6-8,11-12H2,1-3H3

Cluster

Phytochemical cluster
KCF-S cluster	No. 234

Link

ChEMBL

By standard InChI
By standard InChI Main Layer	CHEMBL441356

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name	count
eudicotyledons	2

Family

family name	count
Papaveraceae	2

List (2)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Papaver albiflorum sub.spp.albiflorum	3468	Papaveraceae	eudicotyledons	Viridiplantae
Papaver albiflorum sub.spp.austromoravicum	3468	Papaveraceae	eudicotyledons	Viridiplantae

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	CHEMBL441356	CHEMBL886703 (1)	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	CHEMBL441356	CHEMBL886704 (1)	0 / 0
Q14654	ATP-sensitive inward rectifier potassium channel 11	K	CHEMBL441356	CHEMBL868377 (1)	3 / 4
Q09428	ATP-binding cassette sub-family C member 8	K	CHEMBL441356	CHEMBL868377 (1)	5 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM	preferred title	UniProt
#606176	Diabetes mellitus, permanent neonatal; pndm	Q09428 Q14654
#610374	Diabetes mellitus, transient neonatal, 2	Q09428
#610582	Diabetes mellitus, transient neonatal, 3	Q14654
#256450	Hyperinsulinemic hypoglycemia, familial, 1; hhf1	Q09428
#601820	Hyperinsulinemic hypoglycemia, familial, 2; hhf2	Q14654
#602485	Hyperinsulinemic hypoglycemia, familial, 3; hhf3	Q09428
#240800	Hypoglycemia, leucine-induced; lih	Q09428

KEGG DISEASE (4)

KEGG	disease name	UniProt
H00512	Permanent neonatal diabetes mellitus (PNDM)	Q09428 (related) Q14654 (related)
H00513	Transient neonatal diabetes mellitus (TNDM)	Q09428 (related) Q14654 (related)
H01267	Familial hyperinsulinemic hypoglycemia (HHF)	Q09428 (related) Q14654 (related)
H00409	Type II diabetes mellitus	Q14654 (related)