PCIDB

KNApSAcK Metabolite C00026135

Metabolite

KNApSAcK Entry

id C00026135
Name N-Methylcanadine / (-)-cis-N-Methylcanadine / (-)-alpha-N-Methylcanadine / N-Methyl-(-)-alpha-canadinium
CAS RN 47474-49-7
Standard InChI InChI=1S/C21H24NO4/c1-22-7-6-14-9-19-20(26-12-25-19)10-15(14)17(22)8-13-4-5-18(23-2)21(24-3)16(13)11-22/h4-5,9-10,17H,6-8,11-12H2,1-3H3/q+1/t17-,22-/m0/s1
Standard InChI (Main Layer) InChI=1S/C21H24NO4/c1-22-7-6-14-9-19-20(26-12-25-19)10-15(14)17(22)8-13-4-5-18(23-2)21(24-3)16(13)11-22/h4-5,9-10,17H,6-8,11-12H2,1-3H3

Cluster

Phytochemical cluster
KCF-S cluster No. 234

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL441356

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Rutaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Fagara rhoifolia Lam. 23513 Rutaceae rosids Viridiplantae
Zanthoxylum ocumarense 67937 Rutaceae rosids Viridiplantae

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor CHEMBL441356 CHEMBL886703 (1)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL441356 CHEMBL886704 (1)
0 / 0
Q14654 ATP-sensitive inward rectifier potassium channel 11 K CHEMBL441356 CHEMBL868377 (1)
3 / 4
Q09428 ATP-binding cassette sub-family C member 8 K CHEMBL441356 CHEMBL868377 (1)
5 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#606176 Diabetes mellitus, permanent neonatal; pndm Q09428
Q14654
#610374 Diabetes mellitus, transient neonatal, 2 Q09428
#610582 Diabetes mellitus, transient neonatal, 3 Q14654
#256450 Hyperinsulinemic hypoglycemia, familial, 1; hhf1 Q09428
#601820 Hyperinsulinemic hypoglycemia, familial, 2; hhf2 Q14654
#602485 Hyperinsulinemic hypoglycemia, familial, 3; hhf3 Q09428
#240800 Hypoglycemia, leucine-induced; lih Q09428

KEGG DISEASE (4)

KEGG disease name UniProt
H00512 Permanent neonatal diabetes mellitus (PNDM) Q09428 (related)
Q14654 (related)
H00513 Transient neonatal diabetes mellitus (TNDM) Q09428 (related)
Q14654 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) Q09428 (related)
Q14654 (related)
H00409 Type II diabetes mellitus Q14654 (related)