Platycapnos saxicola
Species
KNApSAcK Entry
| Organism name | Platycapnos saxicola |
|---|---|
| Genus | Platycapnos |
| Family | Fumariaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Platycapnos saxicola |
|---|---|
| Linked NCBI taxonomy ID | 1095362 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001861
|
Glaucine
/ S-(+)-Glaucine / O,O-Dimethylisoboldine |
CHEMBL36536
CHEMBL228082 |
14 / 8 / 6 | No. 20 | No. 4 |
|
||
|
C00025629
|
Sinoacutine
/ (-)-Sinoacutine / (-)-Salutaridine |
CHEMBL402782
CHEMBL404097 |
3 / 4 / 2 | No. 426 | No. 4 |
|
||
|
C00001906
|
Fumarin
/ Biflorine / Protopine / Fumarine / Corydinine |
CHEMBL453019
|
C009093
|
5 / 5 / 4 | 2 / 0 | No. 820 | No. 4 |
|
Human Protein / Gene in interactions
21 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001861 C00001906 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001861 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001906 | 3 / 2 |
| P42574 | Caspase-3 | C14 | C00001861 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025629 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001861 | 1 / 0 |
| Q9BQF6 | Sentrin-specific protease 7 | Enzyme | C00001861 | 0 / 0 |
| Q9GZR1 | Sentrin-specific protease 6 | Enzyme | C00001861 | 0 / 0 |
| Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001861 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001861 | 0 / 0 |
| Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00001861 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00025629 | 4 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001861 | 3 / 3 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001861 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00025629 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001906 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001906 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001861 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001861 | 4 / 3 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001906 | 1 / 0 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00001861 | 0 / 0 |
2 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001906
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001906
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (17)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #601367 | Stroke, ischemic |
P00734
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
KEGG DISEASE (12)
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|