Species

KNApSAcK Entry

Organism name Stephania micrantha H.S.Lo.et.M.Yang
Genus Stephania
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stephania
Linked NCBI taxonomy ID 147243
Linked level genus

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025630 External link 512 Stephanine
/ l-Stephanine
/ (-)-Stephanine
/ (R)-(-)-Stephanine
CHEMBL601020
C054160
1 / 0 / 0 No. 20 No. 4
C00026088 External link 512 (-)-Corypalmine
CHEMBL2334885
CHEMBL2334886
4 / 3 / 0 No. 37 No. 4
C00025846 External link 512 Dehydrostephanine
/ 1,2-Methylenedioxy-8-methoxydehydroaporphine
C030171
No. 416
C00025845 External link 512 Dehydroroemerine
/ Dehydroremerine
/ 6a,7-Didehydroaporheine
CHEMBL1171263
C030170
No. 416
C00025629 External link 512 Sinoacutine
/ (-)-Sinoacutine
/ (-)-Salutaridine
CHEMBL402782
CHEMBL404097
3 / 4 / 2 No. 426 No. 4

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P24941 Cyclin-dependent kinase 2 Cdc2 C00025629 C00025630 0 / 0
P00734 Prothrombin S1A C00025629 4 / 2
P14416 D(2) dopamine receptor Dopamine receptor C00026088 2 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00026088 0 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00026088 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00025629 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00026088 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#103780 Alcohol dependence P14416
#159900 Myoclonic dystonia P14416
#614674 Periodic fever, menstrual cycle-dependent P08908
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (2)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)