Organism name | Ceratocapnos palaestinus |
---|---|
Genus | Ceratocapnos |
Family | Fumariaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Ceratocapnos |
---|---|
Linked NCBI taxonomy ID | 1095358 |
Linked level | genus |
Family in NCBI taxonomy | Papaveraceae |
---|---|
ID | 3465 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | eudicotyledons |
---|---|
ID | 71240 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00027238 |
Thalicmidine
/ Thaliporphine / (+)-Thaliporphine / (S)-O-Methylisoboldine |
CHEMBL1394328
CHEMBL1397308 |
C080702
|
20 / 26 / 56 | No. 20 | No. 4 | ||
C00001869 |
Isoboldine
/ (S)-Isoboldine |
CHEMBL462880
|
19 / 22 / 55 | No. 20 | No. 4 | |||
C00025676 |
Norglaucin
/ Norglaucine / (+)-Norglaucine / O,O-Dimethyllaurelliptine |
No. 20 | No. 4 | |||||
C00001861 |
Glaucine
/ S-(+)-Glaucine / O,O-Dimethylisoboldine |
CHEMBL36536
CHEMBL228082 |
14 / 8 / 6 | No. 20 | No. 4 | |||
C00024773 |
Oxocularine
|
CHEMBL510574
|
No. 74 | |||||
C00024774 |
Oxosarcocapnidine
|
No. 74 | ||||||
C00024772 |
Oxocompostelline
|
No. 74 | ||||||
C00024623 |
Chelidonin
/ Stylophorine / (+)-Chelidonine |
CHEMBL436279
CHEMBL496867 CHEMBL1394506 CHEMBL2009780 |
C062047
|
8 / 19 / 21 | 1 / 2 | No. 233 | No. 4 | |
C00025924 |
Juziphine
/ Yuziphine / (+)-Juziphine |
CHEMBL462956
|
No. 253 | No. 4 | ||||
C00001910 |
Reticuline
/ (+)-Reticuline |
CHEMBL235212
CHEMBL401501 CHEMBL464734 |
C003298
|
1 / 0 / 0 | No. 345 | No. 4 | ||
C00024761 |
Norcularicine
/ (+)-Norcularicine |
No. 361 | ||||||
C00024764 |
Sarcocapnidine
/ (+)-Sarcocapnidine |
CHEMBL510777
|
No. 361 | |||||
C00024765 |
Sarcocapnine
/ (+)-Sarcocapnine |
No. 361 | ||||||
C00024759 |
Enneaphylline
/ (+)-Enneaphylline |
No. 361 | ||||||
C00024758 |
Claviculine
/ (+)-Claviculine |
CHEMBL452512
|
No. 361 | |||||
C00001842 |
Cularine
/ (+)-Cularine |
C064577
|
No. 361 | |||||
C00001841 |
Cularimine
/ (+)-Cularimine |
No. 361 | ||||||
C00024756 |
Celtine
/ (+)-Celtine |
No. 361 | ||||||
C00025629 |
Sinoacutine
/ (-)-Sinoacutine / (-)-Salutaridine |
CHEMBL402782
CHEMBL404097 |
3 / 4 / 2 | No. 426 | No. 4 | |||
C00027394 |
Isosalutaridine
|
No. 426 | No. 4 | |||||
C00028768 |
Fissistigine C
/ O-Methylpallidine |
CHEMBL224744
CHEMBL490139 |
No. 426 | No. 4 | ||||
C00001820 |
Bucuculline
/ Bicucullin / (+)-Bicuculline |
CHEMBL417990
CHEMBL1316579 CHEMBL1437488 CHEMBL1444722 |
D001640
|
30 / 28 / 20 | 0 / 21 | No. 605 | No. 4 | |
C00028026 |
Ceratonicine
|
No. 1978 | ||||||
C00028025 |
Ceratocapnine
|
No. 1978 | ||||||
C00028024 |
Ceratocapnidine
|
No. 1978 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001820 C00001869 C00024623 C00027238 | 1 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00001861 C00001869 C00024623 C00027238 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001820 C00001869 C00024623 C00027238 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001820 C00001869 C00024623 C00027238 | 0 / 1 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001869 C00024623 C00027238 | 1 / 2 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00001861 C00001869 C00027238 | 4 / 3 |
O00255 | Menin | Unclassified protein | C00001869 C00024623 C00027238 | 2 / 5 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001861 C00001869 C00027238 | 0 / 0 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001861 C00001869 C00027238 | 3 / 3 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00001869 C00027238 | 0 / 0 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00001820 C00024623 | 3 / 2 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001869 C00027238 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00001820 C00024623 | 11 / 10 |
P29466 | Caspase-1 | C14 | C00001869 C00027238 | 0 / 0 |
P55210 | Caspase-7 | C14 | C00001869 C00027238 | 0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00001910 C00025629 | 0 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001869 C00027238 | 7 / 37 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001869 C00027238 | 2 / 2 |
O75496 | Geminin | Unclassified protein | C00001820 C00001861 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001820 C00001869 | 0 / 1 |
O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00001820 | 1 / 1 |
P06280 | Alpha-galactosidase A | Enzyme | C00027238 | 1 / 1 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00027238 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001820 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001820 | 0 / 0 |
Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001820 | 0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001861 | 0 / 0 |
Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001861 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00027238 | 0 / 0 |
Q9GZR1 | Sentrin-specific protease 6 | Enzyme | C00001861 | 0 / 0 |
Q9BQF6 | Sentrin-specific protease 7 | Enzyme | C00001861 | 0 / 0 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001861 | 1 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00001861 | 0 / 0 |
P54132 | Bloom syndrome protein | Enzyme | C00027238 | 1 / 2 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025629 | 0 / 0 |
P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00001820 | 1 / 1 |
P42574 | Caspase-3 | C14 | C00001861 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001869 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001820 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00027238 | 3 / 1 |
Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00001861 | 0 / 0 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001869 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001869 | 1 / 4 |
Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00001820 | 0 / 0 |
P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00001820 | 1 / 0 |
P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00001820 | 0 / 0 |
P00734 | Prothrombin | S1A | C00025629 | 4 / 2 |
P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00001820 | 0 / 0 |
Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00001820 | 0 / 0 |
P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00001820 | 0 / 0 |
Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00001820 | 0 / 0 |
P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00001820 | 0 / 0 |
O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00001820 | 0 / 0 |
P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00001820 | 0 / 0 |
P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00001820 | 4 / 2 |
P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00001820 | 0 / 0 |
Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00001820 | 0 / 0 |
P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00001820 | 1 / 0 |
Q9NY46 | Sodium channel protein type 3 subunit alpha | SCN alpha, NaV1.x | C00001820 | 0 / 0 |
Q99250 | Sodium channel protein type 2 subunit alpha | SCN alpha, NaV1.x | C00001820 | 2 / 2 |
P35498 | Sodium channel protein type 1 subunit alpha | SCN alpha, NaV1.x | C00001820 | 3 / 2 |
P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00001861 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
4137 | MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU | microtubule-associated protein tau |
C00024623
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#103780 | Alcohol dependence |
P47869
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#210900 | Bloom syndrome; blm |
P54132
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#607208 | Dravet syndrome |
P18507
P35498 |
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
#612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
#613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
#611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
#613721 | Epileptic encephalopathy, early infantile, 11; eiee11 |
Q99250
|
#133239 | Esophageal cancer |
P04637
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
#604403 | Generalized epilepsy with febrile seizures plus, type 2; gefsp2 |
P35498
|
#611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#211980 | Lung cancer |
P04637
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#609634 | Migraine, familial hemiplegic, 3; fhm3 |
P35498
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
#613679 | Prothrombin deficiency, congenital |
P00734
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#607745 | Seizures, benign familial infantile, 3; bfis3 |
Q99250
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601367 | Stroke, ischemic |
P00734
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00783 | Febrile seizures |
O14764
(related)
P18507 (related) P35498 (related) |
H00223 | Inherited thrombophilia |
P00734
(related)
|
H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00026 | Endometrial Cancer |
P04637
(related)
|
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00125 | Fabry disease |
P06280
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00775 | Familial or sporadic hemiplegic migraine |
P35498
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00606 | Early infantile epileptic encephalopathy |
Q99250
(related)
|
H00806 | Benign familial neonatal and infantile epilepsies |
Q99250
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D002375 | Catalepsy |
C00024623
C00001820 |
D009069 | Movement Disorders |
C00024623
C00001820 |
D006973 | Hypertension |
C00001820
|
D000648 | Amnesia, Retrograde |
C00001820
|
D001008 | Anxiety Disorders |
C00001820
|
D001919 | Bradycardia |
C00001820
|
D004487 | Edema |
C00001820
|
D004827 | Epilepsy |
C00001820
|
D005119 | Extravasation of Diagnostic and Therapeutic Materials |
C00001820
|
D006930 | Hyperalgesia |
C00001820
|
D000647 | Amnesia |
C00001820
|
D007022 | Hypotension |
C00001820
|
D009207 | Myoclonus |
C00001820
|
D009436 | Neural Tube Defects |
C00001820
|
D020078 | Neurogenic Inflammation |
C00001820
|
D020336 | Paraparesis, Spastic |
C00001820
|
D010409 | Penile Diseases |
C00001820
|
D049188 | Prenatal Injuries |
C00001820
|
D012640 | Seizures |
C00001820
|
D013035 | Spasm |
C00001820
|
D013226 | Status Epilepticus |
C00001820
|