| class name | count |
|---|---|
| Magnoliophyta | 14 |
| eudicotyledons | 14 |
| class name | count |
|---|---|
| Annonaceae | 10 |
| Papaveraceae | 6 |
| Ranunculaceae | 5 |
| Lauraceae | 4 |
| Menispermaceae | 3 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00026050
|
Stephenanthrine
/ De-N-methyl-1-isoremerine |
CHEMBL492418
|
C049411
|
5 / 6 / 6 |
|
|
|
C00027120
|
Argentinine
|
CHEMBL458139
|
|
|||
|
C00027361
|
Fenfangjine F
/ (-)-Fenfangjine F |
|
||||
|
C00027430
|
N-Methylsecoglaucine
|
CHEMBL1620038
|
|
|||
|
C00027575
|
Northalicthuberine
|
|
||||
|
C00027590
|
Secoxanthoplanine
|
|
||||
|
C00027595
|
Thalihazine
|
|
||||
|
C00027754
|
O3-Demethylthalictuberine
/ 3-O-Demethylthalicthuberine |
|
||||
|
C00028270
|
Fissicesine
|
|
||||
|
C00029099
|
Thalicthuberine
|
CHEMBL518852
|
|
|||
|
C00029100
|
Thalicthuberine N-oxide
|
|
||||
|
C00033463
|
Uvariopsine
|
|
||||
|
C00050253
|
Thalicpureine
|
CHEMBL464772
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11473 | Vitamin D3 receptor | NR1I1 | C00026050 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00026050 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00026050 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00026050 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00026050 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|