KNApSAcK Metabolite C00026050
Metabolite
KNApSAcK Entry
| id | C00026050 |
|---|---|
| Name | Stephenanthrine / De-N-methyl-1-isoremerine |
| CAS RN | 22108-99-2 |
| Standard InChI | InChI=1S/C19H19NO2/c1-20(2)10-9-14-11-17-19(22-12-21-17)18-15-6-4-3-5-13(15)7-8-16(14)18/h3-8,11H,9-10,12H2,1-2H3 |
| Standard InChI (Main Layer) | InChI=1S/C19H19NO2/c1-20(2)10-9-14-11-17-19(22-12-21-17)18-15-6-4-3-5-13(15)7-8-16(14)18/h3-8,11H,9-10,12H2,1-2H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 639 |
Link
ChEMBL
| By standard InChI | CHEMBL492418 |
|---|---|
| By standard InChI Main Layer | CHEMBL492418 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C049411 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| eudicotyledons | 2 |
| Magnoliophyta | 1 |
Family
| family name | count |
|---|---|
| Menispermaceae | 2 |
| Annonaceae | 1 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Anisocycla cymosa Troupin | 461545 | Menispermaceae | eudicotyledons | Viridiplantae |
| Dennettia tripetala | 489326 | Annonaceae | Magnoliophyta | Viridiplantae |
| Stephania tetrandra S.Moore | 425106 | Menispermaceae | eudicotyledons | Viridiplantae |
Human Protein / Gene in interaction
5 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P11473 | Vitamin D3 receptor | NR1I1 | CHEMBL492418 |
CHEMBL1794311
(1)
|
2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL492418 |
CHEMBL1614458
(1)
|
0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | CHEMBL492418 |
CHEMBL1614211
(1)
|
0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL492418 |
CHEMBL1614421
(1)
CHEMBL1614502
(1)
|
4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | CHEMBL492418 |
CHEMBL1613914
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (6)
| KEGG | disease name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|