Ajuga taiwanensis

• Index
• Plant Species
• Metabolite list (23)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Ajuga taiwanensis
Genus	Ajuga
Family	Labiatae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Ajuga taiwanensis
Linked NCBI taxonomy ID	946572
Linked level	species

Family

Family in NCBI taxonomy	Lamiaceae
ID	4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (23)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00023774	Fucostanol / Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol	CHEMBL66943 CHEMBL186373 CHEMBL400247 CHEMBL1568947	D013265	5 / 0 / 0	1 / 0	No. 53	No. 11
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00010570	8-Acetylharpagide / Harpagide 7-acetate / 8-O-Acetylharpagide	CHEMBL523290 CHEMBL595293	C077626	1 / 2 / 0		No. 56	No. 36
C00031896	Isocyasterone	CHEMBL494249 CHEMBL1736717		2 / 1 / 0		No. 58	No. 11
C00003642	Ajugalactone	CHEMBL2087160		1 / 1 / 0		No. 58	No. 11
C00003649	Cyasterone	CHEMBL494249 CHEMBL1736717	C002082	2 / 1 / 0		No. 58	No. 11
C00031585	Ajugalide E					No. 58	No. 11
C00010569	Harpagide	CHEMBL430183	C033250	1 / 0 / 3		No. 64	No. 36
C00010480	Galiridoside					No. 64	No. 36
C00004565	Kaempferol / Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL150	C006552	76 / 69 / 87	86 / 8	No. 71	No. 15
C00010717	Teuhircoside					No. 100	No. 36
C00031628	beta-Sitosteryl-D-glucoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043		5 / 4 / 2		No. 520
C00002682	Vanillic acid / 3-Methoxy-4-hydroxybenzoic acid	CHEMBL120568	D014641	5 / 3 / 3	5 / 0	No. 1073
C00031586	Ajugamacrin B					No. 1360	No. 43
C00031582	Ajugalide B	CHEMBL1813873				No. 1360	No. 43
C00031583	Ajugalide C	CHEMBL1813870				No. 1360	No. 43
C00031581	Ajugalide A					No. 1360	No. 43
C00031588	Ajugapantin A	CHEMBL522544				No. 1360	No. 43
C00031587	Ajugamarin C1					No. 1360	No. 43
C00030991	Pheophytin-b	CHEMBL499932				No. 2190
C00030990	Pheophytin-a / Pheophytin a5		C061694			No. 2190
C00000208	Nicotinic acid	CHEMBL573 CHEMBL2074803	D009525	100 / 38 / 34	48 / 110	No. 3681	No. 1
C00031584	Ajugalide D					No. 6815

Human Protein / Gene in interactions

176 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08183	Multidrug resistance protein 1	drug	C00003642 C00003649 C00003672 C00004565 C00031896	1 / 0
P03372	Estrogen receptor	NR3A1	C00000208 C00002682 C00003672 C00004565	1 / 1
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00004565 C00031628	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003672 C00023774 C00031628	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000208 C00003672 C00004565	0 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000208 C00003672 C00004565	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000208 C00003672 C00004565	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000208 C00003672 C00004565	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000208 C00003672 C00004565	1 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000208 C00004565 C00010569	0 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00003649 C00031896	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00003672 C00004565	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00000208 C00004565	0 / 1
P22303	Acetylcholinesterase	Hydrolase	C00000208 C00004565	1 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000208 C00004565	2 / 2
P00734	Prothrombin	S1A	C00003672 C00031628	4 / 2
Q9UNA4	DNA polymerase iota	Enzyme	C00002682 C00004565	0 / 0
P15121	Aldose reductase	Enzyme	C00002682 C00004565	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672 C00031628	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000208 C00004565	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000208 C00004565	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00004565 C00023774	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000208 C00004565	1 / 8
O75164	Lysine-specific demethylase 4A	Enzyme	C00000208 C00004565	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003672 C00004565	1 / 1
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00031628	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000208	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00004565	11 / 10
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00004565	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00004565	1 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00004565	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000208	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000208	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000208	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00000208	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000208	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000208	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000208	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000208	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000208	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00023774	0 / 0
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00004565	1 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00004565	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00004565	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000208	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000208	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000208	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000208	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000208	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00004565	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00004565	0 / 0
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00004565	0 / 0
P29466	Caspase-1	C14	C00000208	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000208	1 / 1
P14416	D(2) dopamine receptor	Dopamine receptor	C00000208	2 / 0
P04062	Glucosylceramidase	Enzyme	C00004565	6 / 4
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000208	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000208	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000208	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000208	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000208	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00004565	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000208	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00004565	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000208	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000208	1 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000208	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00004565	1 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000208	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00004565	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00000208	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00004565	0 / 0
P42858	Huntingtin	Unclassified protein	C00002682	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00010570	2 / 0
Q9BXC0	Hydroxycarboxylic acid receptor 1	Hydroxycarboxylic acid receptor	C00000208	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000208	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000208	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000208	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000208	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000208	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000208	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000208	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000208	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000208	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000208	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000208	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000208	1 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000208	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000208	0 / 0
P08311	Cathepsin G	S1A	C00000208	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00004565	0 / 1
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000208	1 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000208	0 / 0
Q12791	Calcium-activated potassium channel subunit alpha-1	KCNM, KCa1.x	C00004565	1 / 1
P03956	Interstitial collagenase	M10A	C00000208	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000208	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00004565	1 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00004565	0 / 0
P08246	Neutrophil elastase	S1A	C00000208	2 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000208	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000208	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000208	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00004565	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000208	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000208	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00004565	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000208	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000208	1 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00004565	4 / 4
P21452	Substance-K receptor	Neurokinin receptor	C00000208	0 / 0
P06276	Cholinesterase	Hydrolase	C00004565	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000208	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000208	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000208	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00004565	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00004565	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000208	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000208	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000208	2 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672	2 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00004565	3 / 3
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004565	2 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00004565	2 / 2
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00004565	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00004565	1 / 1
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000208	0 / 0
Q96FL8	Multidrug and toxin extrusion protein 1	Cation antiporter	C00000208	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000208	1 / 0
P09884	DNA polymerase alpha catalytic subunit	Transferase	C00023774	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000208	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000208	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000208	2 / 2
P35372	Mu-type opioid receptor	Opioid receptor	C00000208	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000208	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000208	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000208	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000208	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00004565	0 / 0
P51580	Thiopurine S-methyltransferase	Enzyme	C00002682	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000208	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00004565	0 / 0
Q9NPH5	NADPH oxidase 4	Enzyme	C00004565	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000208	0 / 0
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00004565	1 / 1
P49019	Hydroxycarboxylic acid receptor 3	Hydroxycarboxylic acid receptor	C00000208	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00004565	7 / 37
P33527	Multidrug resistance-associated protein 1	drugs	C00004565	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00004565	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00004565	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00004565	0 / 0
P10275	Androgen receptor	NR3C4	C00004565	3 / 4
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000208	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000208	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000208	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00004565	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000208	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000208	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00000208	0 / 1
Q04760	Lactoylglutathione lyase	Enzyme	C00004565	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00004565	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000208	0 / 0
P48147	Prolyl endopeptidase	S9A	C00004565	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00004565	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00004565	0 / 0
O00255	Menin	Unclassified protein	C00004565	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00004565	1 / 2
O76082	Solute carrier family 22 member 5	Unclassified protein	C00000208	1 / 2
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00004565	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00004565	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00004565	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00004565	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00023774	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00004565	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00004565	0 / 0

128 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00000208 C00004565
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002682 C00004565
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002682 C00004565
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002682 C00004565
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002682 C00004565
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000208 C00004565
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00000208 C00004565
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000208 C00004565
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000208 C00004565
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00000208 C00004565
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000208 C00004565
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000208 C00004565
1376	CPT2, CPT1, CPTASE, IIAE4	carnitine palmitoyltransferase 2 (EC:2.3.1.21)	C00000208
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00004565
891	CCNB1, CCNB	cyclin B1	C00004565
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00004565
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00004565
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00004565
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00004565
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00004565
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00004565
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00004565
37618			C00004565
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00004565
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00004565
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00004565
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00004565
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00004565
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00004565
1734	DIO2, 5DII, D2, DIOII, SelY, TXDI2	deiodinase, iodothyronine, type II (EC:1.97.1.10)	C00004565
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00004565
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00004565
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00004565
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00004565
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00004565
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00004565
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00004565
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00004565
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00004565
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00004565
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00004565
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00004565
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00004565
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00004565
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00004565
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00004565
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00004565
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00004565
4297	KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS	lysine (K)-specific methyltransferase 2A (EC:2.1.1.43)	C00004565
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00004565
581	BAX, BCL2L4	BCL2-associated X protein	C00004565
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00004565
110357			C00004565
4502	MT2A, MT2	metallothionein 2A	C00004565
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00004565
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00004565
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00004565
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00004565
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00004565
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00004565
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00004565
5241	PGR, NR3C3, PR	progesterone receptor	C00004565
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00004565
8000	PSCA, PRO232	prostate stem cell antigen	C00004565
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00004565
6119	RPA3, REPA3	replication protein A3, 14kDa	C00004565
2810	SFN, YWHAS	stratifin	C00004565
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00004565
6773	STAT2, ISGF-3, P113, STAT113	signal transducer and activator of transcription 2, 113kDa	C00004565
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00004565
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004565
7039	TGFA, TFGA	transforming growth factor, alpha	C00004565
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00004565
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00004565
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00004565
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00004565
7161	TP73, P73	tumor protein p73	C00004565
7352	UCP3, SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	C00004565
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00004565
239	ALOX12, 12-LOX, 12S-LOX, LOG12	arachidonate 12-lipoxygenase (EC:1.13.11.31)	C00004565
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00004565
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00004565
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00004565
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00004565
7402	UTRN, DMDL, DRP, DRP1	utrophin	C00004565
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00004565
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00000208
9370	ADIPOQ, ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28	adiponectin, C1Q and collagen domain containing	C00000208
183	AGT, ANHU, SERPINA8	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	C00000208
197	AHSG, A2HS, AHS, FETUA, HSGA	alpha-2-HS-glycoprotein	C00000208
335	APOA1	apolipoprotein A-I	C00000208
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00000208
506	ATP5B, ATPMB, ATPSB	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14)	C00000208
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00000208
1050	CEBPA, C/EBP-alpha, CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	C00000208
1052	CEBPD, C/EBP-delta, CELF, CRP3, NF-IL6-beta	CCAAT/enhancer binding protein (C/EBP), delta	C00000208
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00004565
84649	DGAT2, ARAT, GS1999FULL	diacylglycerol O-acyltransferase 2 (EC:2.3.1.20 2.3.1.76)	C00000208
2149	F2R, CF2R, HTR, PAR-1, PAR1, TR	coagulation factor II (thrombin) receptor	C00000208
2194	FASN, FAS, OA-519, SDR27X1	fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39)	C00000208
2641	GCG, GLP1, GLP2, GRPP	glucagon	C00000208
2688	GH1, GH, GH-N, GHN, IGHD1B, hGH-N	growth hormone 1	C00000208
338442	HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g	hydroxycarboxylic acid receptor 2	C00000208
8843	HCAR3, GPR109B, HCA3, HM74, PUMAG, Puma-g	hydroxycarboxylic acid receptor 3	C00000208
3458	IFNG, IFG, IFI	interferon, gamma	C00000208
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000208
3952	LEP, LEPD, OB, OBS	leptin	C00000208
3991	LIPE, HSL, LHS	lipase, hormone-sensitive (EC:3.1.1.79)	C00000208
4018	LPA, AK38, APOA, LP	lipoprotein, Lp(a) (EC:3.4.21.-)	C00000208
10062	NR1H3, LXR-a, LXRA, RLD-1	nuclear receptor subfamily 1, group H, member 3	C00000208
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00000208
5175	PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM	platelet/endothelial cell adhesion molecule 1	C00000208
7941	PLA2G7, LDL-PLA2, LP-PLA2, PAFAD, PAFAH	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (EC:3.1.1.47)	C00000208
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00000208
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00000208
5563	PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA	protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31)	C00000208
5729	PTGDR, AS1, ASRT1, DP, DP1, PTGDR1	prostaglandin D2 receptor (DP)	C00000208
5730	PTGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2	prostaglandin D2 synthase 21kDa (brain) (EC:5.3.99.2)	C00000208
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000208
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00000208
56729	RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1	resistin	C00000208
949	SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1	scavenger receptor class B, member 1	C00000208
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00000208
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00000208
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00000208
7448	VTN, V75, VN, VNT	vitronectin	C00000208
10599	SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6	solute carrier organic anion transporter family, member 1B1	C00023774
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002682

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions