Melicope semecarpifolia
Species
KNApSAcK Entry
| Organism name | Melicope semecarpifolia |
|---|---|
| Genus | Melicope |
| Family | Rutaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Melicope semecarpifolia |
|---|---|
| Linked NCBI taxonomy ID | 697038 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (30)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004569
|
Jaranol
/ Kumatakenin / Kumatakillin / Kaempferol 3,7-O-dimethyl ether / 5,4'-Dihydroxy-3,7-dimethoxyflavone / 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL349724
|
No. 3 | No. 15 |
|
|||
|
C00004647
|
Ayanin
/ 3,7,4'-Tri-O-methylquercetin / 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL74898
|
18 / 10 / 2 | No. 3 | No. 15 |
|
||
|
C00004653
|
Retusine
/ Retusin(Ariocarpus) / Quercetin 3,7,3',4'-tetramethyl ether / 5-Hydroxy-3,7,3',4'-tetramethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL77966
|
3 / 3 / 0 | No. 8 | No. 15 |
|
||
|
C00023774
|
Fucostanol
/ Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol |
CHEMBL66943
CHEMBL186373 CHEMBL400247 CHEMBL1568947 |
D013265
|
5 / 0 / 0 | 1 / 0 | No. 53 | No. 11 |
|
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00003647
|
Campesterol
/ 24alpha-Methylcholesterol / (24R)24-Methylcholest-5-en-3beta-ol |
CHEMBL520535
CHEMBL485421 CHEMBL1836653 |
C021273
|
No. 53 | No. 11 |
|
||
|
C00019788
|
Anisocoumarin H
|
CHEMBL408980
|
10 / 6 / 3 | No. 335 |
|
|||
|
C00026410
|
Confusameline
/ 7-Hydroxydictamnine / 7-O-Demethylevolitrine |
CHEMBL503574
|
No. 368 | No. 7 |
|
|||
|
C00026477
|
Ptelein
/ Pteleine / 6-Methoxydictamnine |
CHEMBL486165
|
No. 368 | No. 7 |
|
|||
|
C00002198
|
Skimmianine
|
CHEMBL21396
|
C035932
|
18 / 32 / 62 | No. 368 | No. 7 |
|
|
|
C00002177
|
Kokusaginine
|
CHEMBL278779
|
9 / 7 / 3 | No. 368 | No. 7 |
|
||
|
C00002172
|
Haplopine
|
CHEMBL455007
|
C012345
|
3 / 8 / 3 | No. 368 | No. 7 |
|
|
|
C00002151
|
Dictamine
/ Dictamnine |
CHEMBL22533
|
C026398
|
No. 368 | No. 7 |
|
||
|
C00037133
|
Evolitrin
/ Evolitrine |
CHEMBL401536
|
2 / 0 / 0 | No. 368 | No. 7 |
|
||
|
C00002488
|
Osthol
/ Osthole |
CHEMBL52229
|
C046627
|
12 / 6 / 5 | 7 / 4 | No. 466 | No. 25 |
|
|
C00026458
|
Melicarpinone
|
No. 624 | No. 7 |
|
||||
|
C00002505
|
Xanthyletin
|
CHEMBL303846
|
C020814
|
29 / 43 / 58 | No. 750 | No. 25 |
|
|
|
C00026352
|
Isoplatydesmine
/ 6-Deoxyribaline / (+)-Isoplatydesmine |
CHEMBL21394
|
No. 816 | No. 7 |
|
|||
|
C00002674
|
Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid |
CHEMBL1414
|
C001945
|
12 / 3 / 5 | No. 1073 |
|
||
|
C00026371
|
7,8-Dimethoxyplatydesmine
/ (2S)-(-)-7,8-Dimethoxyplatydesmine |
CHEMBL463650
|
No. 1467 | No. 7 |
|
|||
|
C00026361
|
Platydesmine
/ (+)-Platydesmine |
No. 1467 | No. 7 |
|
||||
|
C00030760
|
Methyl oleate
/ Oleic acid methyl ester / Methyl (Z)-9-octadecenoate |
CHEMBL465725
|
C005576
|
2 / 6 / 5 | No. 1785 |
|
||
|
C00030768
|
Methyl vanillate
|
CHEMBL486214
|
No. 1936 |
|
||||
|
C00030900
|
Osthenol
|
CHEMBL350475
|
C114745
|
2 / 0 / 0 | No. 2087 |
|
||
|
C00026421
|
Dutadrupine
|
No. 2227 | No. 7 |
|
||||
|
C00026363
|
(+)-Semecarpine
|
No. 2227 | No. 7 |
|
||||
|
C00026433
|
Glycocitridine
|
No. 2421 | No. 7 |
|
||||
|
C00026462
|
Melisemine
|
No. 2421 | No. 7 |
|
||||
|
C00026481
|
Semecarpifoline
|
CHEMBL505570
|
No. 2421 | No. 7 |
|
|||
|
C00026457
|
Melicarpine
|
No. 5226 |
|
Human Protein / Gene in interactions
94 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002172 C00002177 C00002198 C00002505 C00019788 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002177 C00002488 C00002505 C00019788 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002177 C00002488 C00002505 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 C00004647 C00004653 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002198 C00002488 C00002505 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002198 C00002488 C00019788 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002177 C00002505 C00019788 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002198 C00002488 C00003672 | 0 / 1 |
| P56817 | Beta-secretase 1 | A1A | C00002488 C00002505 C00030900 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00002505 C00003672 C00023774 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002198 C00003672 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002198 C00002505 | 2 / 2 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00004647 C00004653 | 2 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002198 C00002505 | 3 / 3 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002505 C00002674 | 0 / 0 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002488 C00002505 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002505 C00002674 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002198 C00002505 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002198 C00003672 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002198 C00003672 | 1 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002177 C00002505 | 4 / 2 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00002198 C00003672 | 3 / 2 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002172 C00002505 | 7 / 3 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002505 C00002674 | 1 / 2 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002198 C00002505 | 7 / 37 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002505 C00019788 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002198 C00003672 | 0 / 1 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002505 C00002674 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002488 C00030900 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00004647 C00004653 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002177 C00019788 | 2 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002198 C00019788 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002177 C00019788 | 1 / 1 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002505 C00019788 | 2 / 2 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002505 C00002674 | 1 / 2 |
| O14980 | Exportin-1 | Unclassified protein | C00002488 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00002674 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00002674 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00019788 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002505 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002505 | 4 / 2 |
| P15121 | Aldose reductase | Enzyme | C00002674 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002198 | 1 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00023774 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00030760 | 3 / 1 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002488 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 |
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00002172 | 1 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002198 | 11 / 10 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002505 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00002674 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00002674 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00002488 | 6 / 4 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002505 | 1 / 1 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002488 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00003672 | 1 / 1 |
| P09884 | DNA polymerase alpha catalytic subunit | Transferase | C00023774 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002505 | 1 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002505 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002177 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002505 | 4 / 3 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002177 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00030760 | 3 / 4 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00002674 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00002674 | 1 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00037133 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002505 | 4 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003672 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00002198 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002198 | 1 / 2 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00023774 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00023774 | 0 / 0 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00004647 | 0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00004647 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00004647 | 1 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00004647 | 2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00004647 | 0 / 0 |
| P07437 | Tubulin beta chain | Structural | C00004647 | 0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00004647 | 1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00004647 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00004647 | 2 / 1 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00037133 | 0 / 0 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00004647 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00004647 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00004647 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00004647 | 0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00004647 | 0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00004647 | 1 / 0 |
8 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2180 | ACSL1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2 | acyl-CoA synthetase long-chain family member 1 (EC:6.2.1.3) |
C00002488
|
| 1374 | CPT1A, CPT1, CPT1-L, L-CPT1 | carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) |
C00002488
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00002488
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002488
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002488
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00002488
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002488
|
| 10599 | SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 | solute carrier organic anion transporter family, member 1B1 |
C00023774
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (102)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay |
P55789
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (93)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) |
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|