KCF-S cluster No. 816 (11 metabolites)
Corresponding Phytochemical cluster No. 7
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 21 |
| Embryophyta | 1 |
Cumulative family count
| class name | count |
|---|---|
| Rutaceae | 21 |
| Pelliaceae | 1 |
KEGG BRITE br08003
Categories (1)
| br08003 Category | # of metabolite |
|---|---|
| Quinoline alkaloids | 3 |
metabolites link (3)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Quinoline alkaloids | C10647 | C00002140 |
| Quinoline alkaloids | C10705 | C00002179 |
| Quinoline alkaloids | C10711 | C00002181 |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00002140
|
Balfourodine
|
|
||||
|
C00002179
|
Lemobiline
|
|
||||
|
C00002181
|
Lunacrine
|
CHEMBL2003059
|
|
|||
|
C00025428
|
N-Methylhaplofoline
/ N-Methylkhaplofoline |
CHEMBL24988
|
2 / 13 / 12 |
|
||
|
C00025442
|
Ravesilone
|
|
||||
|
C00026351
|
Ribalinine
/ (-)-Ribalinine / (S)-(-)-Ribalinine |
CHEMBL279711
|
|
|||
|
C00026352
|
Isoplatydesmine
/ 6-Deoxyribaline / (+)-Isoplatydesmine |
CHEMBL21394
|
|
|||
|
C00026362
|
(+)-Ribaliprenylene
|
|
||||
|
C00026469
|
Oligophyline
|
|
||||
|
C00026497
|
Zanthodioline
|
|
||||
|
C00043796
|
Orixalone D
/ (+)-Orixalone D |
|
Human Protein / Gene in interactions
2 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P02545 | Prelamin-A/C | Unclassified protein | C00025428 | 11 / 10 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00025428 | 2 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (13)
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
KEGG DISEASE (12)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|