phytochemical cluster No. 7 (231 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 534 |
| asterids | 75 |
| Liliopsida | 14 |
| Magnoliophyta | 3 |
| eudicotyledons | 3 |
| Embryophyta | 1 |
Cumulative family count (Top 20)
| class name | count |
|---|---|
Rutaceae
|
506 |
|
Rubiaceae
|
27 |
|
Acanthaceae
|
18 |
|
Nitrariaceae
|
11 |
|
Amaryllidaceae
|
11 |
|
Notodontidae
|
11 |
|
Apocynaceae
|
5 |
|
Asteraceae
|
5 |
|
Malvaceae
|
5 |
|
Hydrangeaceae
|
5 |
|
Icacinaceae
|
5 |
|
Brassicaceae
|
4 |
|
Loganiaceae
|
3 |
|
Orchidaceae
|
3 |
|
Cucurbitaceae
|
3 |
|
Ranunculaceae
|
2 |
|
Oleaceae
|
2 |
|
Annonaceae
|
2 |
|
Fabaceae
|
2 |
|
Polygonaceae
|
1 |
KEGG BRITE br08003
Categories (3)
| br08003 Category | # of metabolite |
|---|---|
| Quinoline alkaloids | 49 |
| Quinazoline alkaloids | 14 |
| Acridone alkaloids | 13 |
metabolites link (79)
KCF-S cluster (42)
| KCF-S ID | # of metabolite |
|---|---|
| No. 257 | 25 |
| No. 368 | 20 |
| No. 469 | 17 |
| No. 624 | 13 |
| No. 600 | 12 |
| No. 816 | 11 |
| No. 799 | 10 |
| No. 1009 | 8 |
| No. 1467 | 7 |
| No. 1363 | 7 |
| No. 1378 | 7 |
| No. 1517 | 7 |
| No. 1724 | 6 |
| No. 2197 | 5 |
| No. 2227 | 5 |
| No. 2421 | 5 |
| No. 2365 | 5 |
| No. 1718 | 5 |
| No. 1903 | 5 |
| No. 3076 | 4 |
| No. 2882 | 4 |
| No. 2751 | 4 |
| No. 3585 | 3 |
| No. 3696 | 3 |
| No. 3956 | 3 |
| No. 3116 | 3 |
| No. 3620 | 3 |
| No. 4041 | 3 |
| No. 3142 | 3 |
| No. 4819 | 2 |
| No. 5141 | 2 |
| No. 5227 | 2 |
| No. 5707 | 2 |
| No. 1798 | 2 |
| No. 8566 | 1 |
| No. 7981 | 1 |
| No. 6392 | 1 |
| No. 6623 | 1 |
| No. 7672 | 1 |
| No. 6513 | 1 |
| No. 7591 | 1 |
| No. 6960 | 1 |
Metabolite list (231)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
figure |
|---|---|---|---|---|---|---|---|
|
C00024245
|
8-O-Tigloyldiderroside
|
No. 257 |
|
||||
|
C00024272
|
Nauclealine B
/ (-)-Nauclealine B |
No. 257 |
|
||||
|
C00024271
|
Naucleofficine E
|
CHEMBL1173138
|
No. 257 |
|
|||
|
C00024230
|
Isomaculosidine
/ 6,8-dimethoxydictamnine |
No. 257 |
|
||||
|
C00024248
|
Flindersine
|
CHEMBL1507844
|
1 / 3 / 3 | No. 257 |
|
||
|
C00024249
|
Zanthophyllin
/ Xanthophyllin / Xanthophylline / Zanthophylline |
No. 257 |
|
||||
|
C00035418
|
Oriciacridone F
/ (+)-Oriciacridone F |
No. 257 |
|
||||
|
C00035417
|
Isofebrifugine
|
CHEMBL105789
|
No. 257 |
|
|||
|
C00035416
|
Febrifugine
|
CHEMBL479432
|
C001207
|
No. 257 |
|
||
|
C00024231
|
Isoskimmianine
|
No. 257 |
|
||||
|
C00034720
|
Anisessine
|
No. 257 |
|
||||
|
C00002137
|
Normelicopine
|
No. 257 |
|
||||
|
C00034360
|
Vasnetine
|
No. 257 |
|
||||
|
C00024250
|
Ribalinine
/ (-)-Ribalinine / (S)-(-)-Ribalinine |
CHEMBL279711
|
No. 257 |
|
|||
|
C00024232
|
8-Methoxytaifine
|
No. 257 |
|
||||
|
C00002163
|
gamma-Fagarine
/ 4,8-Dimethoxyfuro[2,3-b]quinoline |
CHEMBL252925
|
C049193
|
8 / 14 / 7 | No. 257 |
|
|
|
C00002187
|
Glycocitrine-III
|
No. 257 |
|
||||
|
C00002186
|
Bosistine
|
No. 257 |
|
||||
|
C00024251
|
N-Methylhaplofoline
/ N-Methylkhaplofoline |
CHEMBL24988
|
2 / 13 / 12 | No. 257 |
|
||
|
C00024253
|
Lemobiline
|
No. 257 |
|
||||
|
C00024243
|
N-Methylflindersine
|
CHEMBL400130
|
No. 257 |
|
|||
|
C00024264
|
1-Hydroxyrutaecarpine
|
No. 257 |
|
||||
|
C00002176
|
Oriciacridone E
|
CHEMBL1668598
|
1 / 0 / 0 | No. 257 |
|
||
|
C00024254
|
Oligophyline
|
No. 257 |
|
||||
|
C00024270
|
Angustoline
/ (-)-Angustoline |
C004167
|
No. 257 |
|
|||
|
C00026492
|
Trispheridine
/ Trisphaeridine |
CHEMBL511443
|
C462033
|
1 / 0 / 0 | No. 368 |
|
|
|
C00026477
|
Glycosminine
/ Glycophymine / N-Demethylarborine |
CHEMBL1604716
|
C015247
|
4 / 1 / 2 | No. 368 |
|
|
|
C00002177
|
(-)-Marshmine
|
No. 368 |
|
||||
|
C00026468
|
Semecarpifoline
|
CHEMBL505570
|
No. 368 |
|
|||
|
C00002151
|
Maculosidine
|
CHEMBL1966898
|
No. 368 |
|
|||
|
C00026434
|
Lunacridine
|
No. 368 |
|
||||
|
C00026440
|
Xanthoxoline
|
No. 368 |
|
||||
|
C00002172
|
Grandisinine
|
No. 368 |
|
||||
|
C00002159
|
5-Methoxymaculine
|
CHEMBL461610
|
No. 368 |
|
|||
|
C00002183
|
Atalaphylline
|
No. 368 |
|
||||
|
C00002161
|
Ptelein
/ Pteleine / 6-Methoxydictamnine |
CHEMBL486165
|
No. 368 |
|
|||
|
C00002184
|
Buxifoliadine A
|
No. 368 |
|
||||
|
C00026415
|
6,11-Dihydroxy-10-methoxy-3,3,12-trimethyl-3,12-dihydro-7H-pyrano[2,3-c]acridin-7-one
|
No. 368 |
|
||||
|
C00026452
|
Peganine
/ Vasicine / (-)-Linarine / (-)-Peganine / (-)-Vasicine |
CHEMBL1186527
CHEMBL1456364 CHEMBL2163791 |
C019592
|
3 / 2 / 3 | No. 368 |
|
|
|
C00026410
|
Yukocitrine
|
No. 368 |
|
||||
|
C00037133
|
Rutacridone epoxide
|
CHEMBL1968498
|
C059482
|
No. 368 |
|
||
|
C00002129
|
Citrusamine
|
No. 368 |
|
||||
|
C00002195
|
Haplotubine
|
No. 368 |
|
||||
|
C00026391
|
Bis-5-hydroxynoracronycine
|
No. 368 |
|
||||
|
C00002198
|
(+)-Tecleoxine
/ (+)-Tecleanatalensine A |
No. 368 |
|
||||
|
C00002144
|
Furacridone
|
No. 469 |
|
||||
|
C00024261
|
(+)-Ribaliprenylene
|
No. 469 |
|
||||
|
C00024260
|
Orixalone D
/ (+)-Orixalone D |
No. 469 |
|
||||
|
C00002156
|
Kokusagine
/ 7,8-Methylenedioxydictamnine |
CHEMBL491782
|
No. 469 |
|
|||
|
C00024240
|
Zanthobungeanine
/ 7-Methoxy-N-methylflindersine / 8-Methoxy-N-methylflindersine |
No. 469 |
|
||||
|
C00024259
|
Zanthodioline
|
No. 469 |
|
||||
|
C00024267
|
7-Hydroxyrutaecarpine
|
No. 469 |
|
||||
|
C00030895
|
Leiokinine A
|
C068516
|
No. 469 |
|
|||
|
C00024239
|
Stauranthine
|
No. 469 |
|
||||
|
C00024218
|
Iso-gamma-fagarine
|
CHEMBL447997
|
6 / 2 / 2 | No. 469 |
|
||
|
C00024238
|
Veprisine
/ NSC 363785 / 7,8-Dimethoxy-N-methylflindersine |
CHEMBL21801
|
No. 469 |
|
|||
|
C00024237
|
Isomaculine
|
No. 469 |
|
||||
|
C00033009
|
Oriciacridone D
/ (+)-Oriciacridone D |
No. 469 |
|
||||
|
C00024244
|
Isodutadrupine
|
No. 469 |
|
||||
|
C00034721
|
Anisotine
|
No. 469 |
|
||||
|
C00002139
|
Evoxanthine
|
No. 469 |
|
||||
|
C00024263
|
3-Hydroxyrutaecarpine
|
No. 469 |
|
||||
|
C00002185
|
Buxifoliadine-B
|
No. 600 |
|
||||
|
C00033583
|
9-Methoxycamptothecin
|
CHEMBL91945
CHEMBL522112 |
1 / 0 / 0 | No. 600 |
|
||
|
C00033572
|
Rutacridone
|
CHEMBL563582
CHEMBL2003193 |
C059481
|
No. 600 |
|
||
|
C00026404
|
Noracronycine
|
CHEMBL509922
|
C046848
|
No. 600 |
|
||
|
C00034059
|
2-Acetylfuran
|
CHEMBL75854
|
C039669
|
No. 600 |
|
||
|
C00037236
|
Isogravacridonechlorine
|
CHEMBL486378
|
C069662
|
No. 600 |
|
||
|
C00026348
|
Dubinidine
|
CHEMBL1255737
CHEMBL1520045 CHEMBL1552847 |
12 / 18 / 18 | No. 600 |
|
||
|
C00026464
|
Edulitine
/ Robustinin / Robustinine |
CHEMBL256497
|
No. 600 |
|
|||
|
C00026463
|
Deoxypeganine
|
CHEMBL355821
|
C048835
|
1 / 1 / 0 | No. 600 |
|
|
|
C00026366
|
Citbismine-F
|
No. 600 |
|
||||
|
C00002158
|
Flindersiamine
/ 8-Methoxy-6,7-methylenedioxydictamnine |
CHEMBL503519
|
C012321
|
No. 600 |
|
||
|
C00026426
|
(-)-Edulinine
/ (S)-(-)-Edulinine |
No. 600 |
|
||||
|
C00026449
|
(-)-cis-1,2-Dihydroxy-1,2-dihydromedicosmine
|
No. 624 |
|
||||
|
C00042650
|
Cusparine
|
CHEMBL456954
|
No. 624 |
|
|||
|
C00026487
|
Toddaquinoline
|
CHEMBL470880
|
No. 624 |
|
|||
|
C00026447
|
Acronydine
/ Acronidine / 5,11-Dimethoxy-3,3-dimethyl-3H-furo-[2,3-b]pyrano[3,2-b]quinoline |
No. 624 |
|
||||
|
C00026446
|
Medicosmine
|
No. 624 |
|
||||
|
C00026445
|
Dutadrupine
|
No. 624 |
|
||||
|
C00026444
|
Evoxanthidine
|
No. 624 |
|
||||
|
C00026400
|
Dihydroperfamine
|
No. 624 |
|
||||
|
C00026448
|
(+)-Semecarpine
|
No. 624 |
|
||||
|
C00002174
|
Buntanine
|
No. 624 |
|
||||
|
C00026450
|
Vasicine
/ (-)-Linarine / (-)-Peganine / (-)-Vasicine |
CHEMBL1186527
CHEMBL1456364 CHEMBL2163791 |
C019592
|
3 / 2 / 3 | No. 624 |
|
|
|
C00026416
|
Citracridone-I
|
CHEMBL451706
|
C053119
|
No. 624 |
|
||
|
C00026458
|
Vasicinol
|
No. 624 |
|
||||
|
C00002162
|
Evolitrin
/ Evolitrine |
CHEMBL401536
|
2 / 0 / 0 | No. 799 |
|
||
|
C00026484
|
Arborine
|
CHEMBL448122
|
C014013
|
No. 799 |
|
||
|
C00026438
|
Kalasinamide
|
No. 799 |
|
||||
|
C00025446
|
Cinchonidine
|
CHEMBL15134
CHEMBL461234 CHEMBL518804 CHEMBL533841 CHEMBL588619 CHEMBL611480 CHEMBL1414315 CHEMBL1477170 CHEMBL1590546 CHEMBL2079612 CHEMBL2357353 |
C041622
|
13 / 10 / 8 | No. 799 |
|
|
|
C00002189
|
Nkolbisine
/ Montrifoline / (-)-Nkolbisine / (-)-Montrifoline |
No. 799 |
|
||||
|
C00026399
|
Haplophyllidine
|
CHEMBL1864455
|
2 / 0 / 0 | No. 799 |
|
||
|
C00026394
|
Acetylhaplophyllidine
|
CHEMBL1880744
|
1 / 0 / 0 | No. 799 |
|
||
|
C00025447
|
Cupreine
/ Ultraquinine / Desmethylquinine / O-Demethylquinine / O6'-Demethylquinine |
C029819
|
No. 799 |
|
|||
|
C00025448
|
Hydroquinidine
|
CHEMBL531471
CHEMBL531472 CHEMBL588934 CHEMBL602767 CHEMBL1436416 CHEMBL1531111 CHEMBL1617471 CHEMBL1740727 CHEMBL1906890 CHEMBL2079611 CHEMBL2092739 CHEMBL2305514 CHEMBL2355802 |
C014486
|
9 / 12 / 15 | 0 / 4 | No. 799 |
|
|
C00026443
|
Natsucitrine-II
|
No. 799 |
|
||||
|
C00002179
|
Buxifoliadine-G
|
No. 816 |
|
||||
|
C00002181
|
Evoprenine
|
No. 816 |
|
||||
|
C00025428
|
Norgraveoline
|
CHEMBL2335132
|
1 / 0 / 0 | No. 816 |
|
||
|
C00026469
|
Glycocitridine
|
No. 816 |
|
||||
|
C00025442
|
Quinine
|
CHEMBL97
CHEMBL15088 CHEMBL21578 CHEMBL1294 CHEMBL170 CHEMBL387326 CHEMBL407725 CHEMBL512340 CHEMBL522505 CHEMBL460606 CHEMBL601807 CHEMBL576997 CHEMBL1358565 CHEMBL1364159 CHEMBL1616938 CHEMBL1741006 CHEMBL1878119 CHEMBL2355467 |
D011803
|
48 / 55 / 40 | 18 / 83 | No. 816 |
|
|
C00026362
|
Glycobismine G
|
No. 816 |
|
||||
|
C00026497
|
Graveolinine
|
CHEMBL2205100
|
No. 816 |
|
|||
|
C00002140
|
Marshdine
|
No. 816 |
|
||||
|
C00026351
|
7,8-Dimethoxyplatydesmine
/ (2S)-(-)-7,8-Dimethoxyplatydesmine |
CHEMBL463650
|
No. 816 |
|
|||
|
C00043796
|
Glycoperine
|
CHEMBL1613094
|
3 / 2 / 2 | No. 816 |
|
||
|
C00026352
|
Glycobismine-E
|
No. 816 |
|
||||
|
C00001685
|
5-Hydroxyarborinine
|
CHEMBL1928574
|
No. 1009 |
|
|||
|
C00027032
|
Cherianoine
|
No. 1009 |
|
||||
|
C00046191
|
Bucharaine
|
CHEMBL1338870
|
7 / 10 / 13 | No. 1009 |
|
||
|
C00025154
|
Graveoline
|
CHEMBL1371756
|
12 / 18 / 18 | No. 1009 |
|
||
|
C00027710
|
N-Methylswietenidine B
|
No. 1009 |
|
||||
|
C00026551
|
Casimiroin
|
CHEMBL492762
|
2 / 2 / 2 | No. 1009 |
|
||
|
C00034074
|
Camptothecin
|
CHEMBL65
CHEMBL276820 CHEMBL71836 |
D002166
|
140 / 99 / 97 | 79 / 11 | No. 1009 |
|
|
C00001766
|
Buxifoliadine-H
|
CHEMBL465629
|
No. 1009 |
|
|||
|
C00028697
|
Deoxyaniflorine
|
No. 1363 |
|
||||
|
C00002182
|
N-Methylatalaphylline
|
No. 1363 |
|
||||
|
C00024365
|
Arolycoricidinol
|
CHEMBL1980408
|
No. 1363 |
|
|||
|
C00024366
|
N-Methylcrinasiadine
|
CHEMBL2208201
|
No. 1363 |
|
|||
|
C00002169
|
Dictamine
/ Dictamnine |
CHEMBL22533
|
C026398
|
No. 1363 |
|
||
|
C00002328
|
Taifine
|
No. 1363 |
|
||||
|
C00025430
|
Quinidine
/ (+)-Quinidine |
CHEMBL97
CHEMBL15088 CHEMBL21578 CHEMBL1294 CHEMBL170 CHEMBL387326 CHEMBL407725 CHEMBL512340 CHEMBL522505 CHEMBL460606 CHEMBL601807 CHEMBL576997 CHEMBL1358565 CHEMBL1364159 CHEMBL1616938 CHEMBL1741006 CHEMBL1878119 CHEMBL2355467 |
D011802
|
48 / 55 / 40 | 28 / 83 | No. 1363 |
|
|
C00002193
|
Chlorodesnkolbisine
/ (+)-Chlorodesnkolbisine / 6-(2'-Hydroxy-3'-chloroprenyloxy)-4,7-dimethoxyfuroquinoline |
No. 1378 |
|
||||
|
C00002173
|
Glycocitrine IV
|
CHEMBL463652
|
1 / 0 / 0 | No. 1378 |
|
||
|
C00002147
|
Buxifoliadine-F
|
No. 1378 |
|
||||
|
C00026417
|
Atalaphyllidine
|
CHEMBL452220
|
No. 1378 |
|
|||
|
C00031117
|
Oriciacridone C
/ (+)-Oriciacridone C |
No. 1378 |
|
||||
|
C00026466
|
Swietenidin B
|
No. 1378 |
|
||||
|
C00026411
|
Acronycine
|
CHEMBL285852
|
D000175
|
No. 1378 |
|
||
|
C00002153
|
Skimmianine
|
CHEMBL21396
|
C035932
|
18 / 32 / 62 | No. 1467 |
|
|
|
C00026371
|
Atalanine
|
No. 1467 |
|
||||
|
C00002141
|
Toddaliopsin D
|
No. 1467 |
|
||||
|
C00002203
|
Isotaifine
|
No. 1467 |
|
||||
|
C00002192
|
Methylnkolbisine
|
No. 1467 |
|
||||
|
C00026361
|
Glycobismine F
|
No. 1467 |
|
||||
|
C00002194
|
7-(2'-Hydroxy-3'-chloroprenyloxy)-4,8-dimethoxyfuroquinoline
|
No. 1467 |
|
||||
|
C00024257
|
Lunacrine
|
CHEMBL2003059
|
No. 1517 |
|
|||
|
C00024256
|
Balfourodine
|
No. 1517 |
|
||||
|
C00024246
|
Haplophytin A
|
No. 1517 |
|
||||
|
C00002138
|
Melicopine
|
CHEMBL1876999
|
7 / 8 / 4 | No. 1517 |
|
||
|
C00024236
|
Isokokusagine
|
No. 1517 |
|
||||
|
C00024258
|
Ravesilone
|
No. 1517 |
|
||||
|
C00024255
|
Isoplatydesmine
/ 6-Deoxyribaline / (+)-Isoplatydesmine |
CHEMBL21394
|
No. 1517 |
|
|||
|
C00026420
|
Phaitanthrin C
/ (-)-Phaitanthrin C |
CHEMBL452806
|
No. 1718 |
|
|||
|
C00036304
|
Glycobismine A
|
No. 1718 |
|
||||
|
C00002171
|
Glycocitrine-I
|
CHEMBL508186
|
No. 1718 |
|
|||
|
C00026401
|
(+)-Dihydroperfamine
|
No. 1718 |
|
||||
|
C00026475
|
Melisemine
|
No. 1718 |
|
||||
|
C00024233
|
Dictangustine A
|
No. 1724 |
|
||||
|
C00024274
|
Crinasiadine
|
No. 1724 |
|
||||
|
C00002130
|
1-Hydroxy-3-methoxy-N-methylacridone
|
CHEMBL1094824
|
No. 1724 |
|
|||
|
C00024269
|
Angustine
|
C004166
|
No. 1724 |
|
|||
|
C00024235
|
Isodictamine
/ Isodictamnine |
CHEMBL509839
|
No. 1724 |
|
|||
|
C00024247
|
Haplamine
/ 6-Methoxyflindersine |
CHEMBL1488010
|
23 / 37 / 65 | No. 1724 |
|
||
|
C00039983
|
Acrophylline
|
CHEMBL447116
|
C093762
|
No. 1798 |
|
||
|
C00002200
|
Isopteleine
/ 6-Methoxydictamnine |
No. 1798 |
|
||||
|
C00026422
|
Acutifolin
|
No. 1903 |
|
||||
|
C00026346
|
Platydesmine
/ (+)-Platydesmine |
No. 1903 |
|
||||
|
C00002180
|
Tegerrardin B
|
No. 1903 |
|
||||
|
C00026402
|
Perfamine
/ (+)-Perfamine |
CHEMBL1543862
|
2 / 0 / 0 | No. 1903 |
|
||
|
C00050204
|
Bucharidine
|
CHEMBL1891586
|
1 / 0 / 0 | No. 1903 |
|
||
|
C00024273
|
Arolycoricidine
|
No. 2197 |
|
||||
|
C00024265
|
Rutaecarpine
|
CHEMBL85139
|
C028632
|
35 / 47 / 67 | 5 / 0 | No. 2197 |
|
|
C00035415
|
Hydrachine A
/ (-)-Hydrachine A |
No. 2197 |
|
||||
|
C00037364
|
Hyemaline
|
No. 2197 |
|
||||
|
C00002157
|
Tecleine
|
No. 2197 |
|
||||
|
C00002128
|
Citrusinine II
|
CHEMBL465847
|
1 / 0 / 0 | No. 2227 |
|
||
|
C00041983
|
Galipine
|
No. 2227 |
|
||||
|
C00042723
|
Melochinone
|
C011298
|
No. 2227 |
|
|||
|
C00026363
|
Glycobismine-D
|
No. 2227 |
|
||||
|
C00026421
|
Tryptanthrin
/ Tryptanthrine / Couroupitine A |
CHEMBL306946
|
C046243
|
20 / 22 / 23 | 2 / 0 | No. 2227 |
|
|
C00002149
|
Toddaliopsin B
|
No. 2365 |
|
||||
|
C00002191
|
Evoxine
/ 7-(2,3-Dihydroxy-3-methyl-butyl)oxy-8-methyldictamnine |
CHEMBL1317300
CHEMBL1395597 CHEMBL1416006 |
14 / 9 / 9 | No. 2365 |
|
||
|
C00026252
|
Balfourodinium
|
No. 2365 |
|
||||
|
C00026250
|
Veprisinium
|
C034381
|
No. 2365 |
|
|||
|
C00002201
|
Melicarpinone
|
No. 2365 |
|
||||
|
C00026423
|
Ptelefoliarine
/ (-)-Ptelefoliarine |
No. 2421 |
|
||||
|
C00026433
|
Edulinine
/ (+)-Edulinine / (+)-(R)-Edulinine / (R)-(+)-Edulinine |
C060993
|
No. 2421 |
|
|||
|
C00026462
|
Peganol
|
CHEMBL2165578
|
1 / 0 / 0 | No. 2421 |
|
||
|
C00026481
|
Glycosminine
|
CHEMBL1604716
|
C015247
|
4 / 1 / 2 | No. 2421 |
|
|
|
C00002199
|
Anhydroevoxine
/ 7-(2,3-Epoxy-3-methylbutyl)oxy-8-methoxy-dictamnine |
No. 2421 |
|
||||
|
C00002167
|
Confusameline
/ 7-Hydroxydictamnine / 7-O-Demethylevolitrine |
CHEMBL503574
|
No. 2751 |
|
|||
|
C00002168
|
Robustine
/ (-)-Rutacridone |
CHEMBL402862
|
No. 2751 |
|
|||
|
C00026245
|
N-Methyldihydroquinicinol
|
No. 2751 |
|
||||
|
C00002136
|
Normelicopidine
|
No. 2751 |
|
||||
|
C00029148
|
Vasicolinone
|
No. 2882 |
|
||||
|
C00046757
|
Echinorine
|
No. 2882 |
|
||||
|
C00026493
|
Dubamine
|
CHEMBL502774
|
20 / 38 / 55 | No. 2882 |
|
||
|
C00002152
|
Kokusaginine
|
CHEMBL278779
|
9 / 7 / 3 | No. 2882 |
|
||
|
C00026486
|
Glycophymoline
|
No. 3076 |
|
||||
|
C00046206
|
Evodiamine
|
CHEMBL81925
CHEMBL486598 |
6 / 7 / 4 | No. 3076 |
|
||
|
C00027321
|
Swietenidine A
|
No. 3076 |
|
||||
|
C00002146
|
Furoparadine
|
No. 3076 |
|
||||
|
C00026256
|
Ribalinium
|
No. 3116 |
|
||||
|
C00026239
|
Hydrocupreine
/ Dihydrocupreine / 10,11-Dihydrocupreine / O6'-Demethylhydroquinine / 6'-Hydroxydihydrocinchonidine |
CHEMBL532678
CHEMBL587165 |
C029820
|
No. 3116 |
|
||
|
C00002132
|
1,3-Dimethoxy-N-methylacridone
|
No. 3116 |
|
||||
|
C00002150
|
1-Hydroxy-N-methylacridone
|
CHEMBL1288799
|
3 / 5 / 4 | No. 3142 |
|
||
|
C00002202
|
Koniamborine
|
CHEMBL486605
|
No. 3142 |
|
|||
|
C00026253
|
Pteleatine
|
No. 3142 |
|
||||
|
C00025426
|
Lunamarine
|
No. 3585 |
|
||||
|
C00002178
|
Buxifoliadine-C
|
No. 3585 |
|
||||
|
C00002154
|
Halfordinine
/ 6,7,8-Trimethoxydictamnine |
No. 3585 |
|
||||
|
C00030893
|
Deoxyvasicinone
|
CHEMBL456881
|
C025696
|
25 / 13 / 9 | No. 3620 |
|
|
|
C00002196
|
Maculosine
|
No. 3620 |
|
||||
|
C00030894
|
Leptomerine
|
No. 3620 |
|
||||
|
C00029611
|
Vasicinolone
|
No. 3696 |
|
||||
|
C00002145
|
Furofoline I
|
No. 3696 |
|
||||
|
C00029371
|
Vasicinone
|
CHEMBL1864065
|
C052548
|
1 / 0 / 0 | No. 3696 |
|
|
|
C00029180
|
Aniflorine
|
No. 3956 |
|
||||
|
C00002134
|
Japonine
|
No. 3956 |
|
||||
|
C00002133
|
Arborinine
|
CHEMBL349609
|
C022784
|
1 / 0 / 0 | No. 3956 |
|
|
|
C00002175
|
Junosine
|
No. 4041 |
|
||||
|
C00046023
|
O-Methylptelofolonium
|
No. 4041 |
|
||||
|
C00002160
|
Maculine
|
CHEMBL503675
|
No. 4041 |
|
|||
|
C00002165
|
Heliparvifoline
/ 7-Hydroxy-6-methoxydictamnine |
No. 4819 |
|
||||
|
C00030896
|
Echinopsine
|
C007574
|
No. 4819 |
|
|||
|
C00002197
|
(-)-Isotecleoxine
|
No. 5141 |
|
||||
|
C00046780
|
Haplodimerine
|
No. 5141 |
|
||||
|
C00002131
|
Tegerrardin A
|
CHEMBL1095073
|
No. 5227 |
|
|||
|
C00026441
|
Toddaliopsin A
|
No. 5227 |
|
||||
|
C00002164
|
Delbine
/ Delbine (Monnieria) |
No. 5707 |
|
||||
|
C00002148
|
Toddaliopsin C
|
No. 5707 |
|
||||
|
C00002188
|
Evolatine
|
No. 6392 |
|
||||
|
C00002166
|
Haplopine
|
CHEMBL455007
|
C012345
|
3 / 8 / 3 | No. 6513 |
|
|
|
C00002190
|
Nigdenine
|
No. 6623 |
|
||||
|
C00002142
|
Normelicopicine
|
CHEMBL453816
|
No. 6960 |
|
|||
|
C00001727
|
Citrusinine I
|
CHEMBL451705
|
C062044
|
1 / 0 / 0 | No. 7591 |
|
|
|
C00002155
|
Acronycidine
/ 5,7,8-Trimethoxydictamnine |
No. 7672 |
|
||||
|
C00002170
|
O-Ethylnordictamnine
|
No. 7981 |
|
||||
|
C00002143
|
Melicopicine
|
CHEMBL455628
|
No. 8566 |
|
Human Protein / Gene in interactions
204 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001766 C00002142 C00002145 C00002150 C00002152 C00002158 C00002159 C00002166 C00002169 C00002172 C00002173 C00002177 C00002193 C00002198 C00026394 C00026444 C00031117 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001766 C00002145 C00002150 C00002152 C00002158 C00002159 C00002166 C00002169 C00002173 C00002193 C00002198 C00026394 C00026444 C00026475 C00031117 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001766 C00002145 C00002147 C00002150 C00002153 C00002158 C00002169 C00002173 C00002193 C00002198 C00002200 C00031117 | 0 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001766 C00002143 C00002145 C00002147 C00002152 C00002171 C00002177 C00002187 C00002193 C00026394 C00026444 C00031117 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001766 C00002145 C00002147 C00002150 C00002153 C00002158 C00002169 C00002193 C00002198 C00002200 C00026394 C00031117 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001766 C00002145 C00002147 C00002150 C00002153 C00002158 C00002169 C00002193 C00002198 C00002200 C00026394 C00031117 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001766 C00002145 C00002147 C00002150 C00002153 C00002168 C00002193 C00002200 C00002202 C00026245 C00026475 C00031117 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001766 C00002145 C00002150 C00002158 C00002162 C00002169 C00002173 C00002193 C00002198 C00026394 C00031117 | 3 / 3 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001727 C00001766 C00002145 C00002147 C00002150 C00002153 C00002158 C00002169 C00002193 C00002198 C00031117 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002142 C00002145 C00002158 C00002159 C00002166 C00002169 C00002173 C00002198 C00025428 C00026394 C00026444 | 2 / 2 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001766 C00002145 C00002147 C00002150 C00002153 C00002158 C00002169 C00002173 C00002193 C00002198 C00031117 | 1 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002142 C00002145 C00002168 C00002173 C00002193 C00002198 C00002200 C00026245 C00026394 C00031117 | 1 / 2 |
| O75496 | Geminin | Unclassified protein | C00002145 C00002147 C00002171 C00002193 C00002198 C00002200 C00026394 C00026444 C00031117 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002147 C00002169 C00002177 C00002187 C00002193 C00026394 C00026401 C00026444 C00031117 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001766 C00002145 C00002147 C00002152 C00002177 C00002193 C00002200 C00026394 C00031117 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001766 C00002145 C00002147 C00002153 C00002173 C00002193 C00002198 C00026394 C00031117 | 3 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001766 C00002145 C00002152 C00002153 C00002169 C00002198 C00002200 C00025428 C00026394 | 11 / 10 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001766 C00002145 C00002152 C00002158 C00002159 C00002198 C00002200 C00026394 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001766 C00002145 C00002152 C00002153 C00002159 C00002193 C00026394 C00031117 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002142 C00002145 C00002150 C00002159 C00002198 C00002200 C00026394 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00002142 C00002145 C00002173 C00002193 C00002198 C00026394 C00031117 | 2 / 5 |
| P06276 | Cholinesterase | Hydrolase | C00002150 C00002191 C00002193 C00026250 C00026252 C00031117 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001766 C00002145 C00002150 C00002187 C00002193 C00031117 | 1 / 1 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002145 C00002158 C00002191 C00002198 C00002200 C00026252 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001766 C00002145 C00002152 C00002198 C00026394 | 7 / 37 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001727 C00002145 C00002200 C00029148 C00029611 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00001766 C00002145 C00002152 C00002200 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00001766 C00002142 C00002145 C00002152 | 4 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002150 C00002152 C00002177 C00026394 | 0 / 0 |
| O60911 | Cathepsin L2 | C1A | C00024249 C00024250 C00030895 C00033009 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001727 C00002177 C00002200 C00026394 | 2 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00002145 C00002200 C00024231 C00026394 | 1 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001766 C00002145 C00002169 C00037133 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002147 C00002152 C00002200 C00024231 | 4 / 3 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002152 C00002159 C00002172 C00002187 | 7 / 3 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00001766 C00002193 C00031117 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002177 C00002193 C00031117 | 4 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002150 C00002168 C00026245 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002145 C00002149 C00002150 | 1 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00002145 C00002193 C00031117 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00002168 C00024231 C00026245 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002150 C00002158 C00026394 | 1 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002150 C00002193 C00031117 | 1 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002145 C00002193 C00031117 | 2 / 2 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001766 C00002145 C00037133 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001766 C00002145 C00002200 | 0 / 3 |
| P40225 | Thrombopoietin | Unclassified protein | C00001766 C00002145 C00002153 | 1 / 1 |
| P54132 | Bloom syndrome protein | Enzyme | C00001766 C00002145 C00002153 | 1 / 2 |
| P02768 | Serum albumin | Secreted protein | C00002145 C00002193 C00031117 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00001766 C00002152 C00002200 | 1 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001766 C00002147 C00002177 | 1 / 1 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001727 C00001766 | 0 / 0 |
| P35498 | Sodium channel protein type 1 subunit alpha | SCN alpha, NaV1.x | C00002193 C00031117 | 3 / 2 |
| Q99250 | Sodium channel protein type 2 subunit alpha | SCN alpha, NaV1.x | C00002193 C00031117 | 2 / 2 |
| Q9NY46 | Sodium channel protein type 3 subunit alpha | SCN alpha, NaV1.x | C00002193 C00031117 | 0 / 0 |
| O76082 | Solute carrier family 22 member 5 | Unclassified protein | C00002193 C00031117 | 1 / 2 |
| Q9H015 | Solute carrier family 22 member 4 | Unclassified protein | C00002193 C00031117 | 1 / 1 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00002193 C00031117 | 1 / 0 |
| O15244 | Solute carrier family 22 member 2 | Drug uniporter | C00002193 C00031117 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00002193 C00031117 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00002145 C00002200 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00002191 C00026252 | 2 / 3 |
| Q96FL8 | Multidrug and toxin extrusion protein 1 | Cation antiporter | C00002193 C00031117 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001766 C00002145 | 0 / 0 |
| O95342 | Bile salt export pump | drug | C00002193 C00031117 | 2 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002193 C00031117 | 0 / 0 |
| P04156 | Major prion protein | Surface antigen | C00002193 C00031117 | 6 / 2 |
| P22460 | Potassium voltage-gated channel subfamily A member 5 | KCNA, Kv1.x (Shaker) | C00002193 C00031117 | 1 / 1 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00001727 C00001766 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002150 C00002152 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00002193 C00031117 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002137 C00002145 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002145 C00002150 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002145 C00002152 | 0 / 0 |
| Q14524 | Sodium channel protein type 5 subunit alpha | SCN alpha, NaV1.x | C00002193 C00031117 | 9 / 7 |
| Q86VL8 | Multidrug and toxin extrusion protein 2 | Cation antiporter | C00002193 C00031117 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002145 C00002158 | 1 / 1 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001766 C00002145 | 5 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002150 C00002187 | 0 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00002193 C00031117 | 1 / 1 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00001766 C00002145 | 2 / 2 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002158 C00002187 | 0 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001727 C00001766 | 4 / 4 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00002193 C00031117 | 3 / 1 |
| Q8TCC7 | Solute carrier family 22 member 8 | Antiporter | C00002193 C00031117 | 0 / 0 |
| P46721 | Solute carrier organic anion transporter family member 1A2 | Unclassified protein | C00002193 C00031117 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00002193 C00031117 | 5 / 3 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002152 C00002159 | 4 / 2 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00002193 C00031117 | 1 / 0 |
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00002193 C00031117 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002150 C00002152 | 0 / 0 |
| P42226 | Signal transducer and activator of transcription 6 | Unclassified protein | C00002145 C00002153 | 0 / 0 |
| P11940 | Polyadenylate-binding protein 1 | Unclassified protein | C00002187 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00002145 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002145 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002145 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00002145 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002145 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002145 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002145 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00002145 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002145 | 1 / 0 |
| Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | Pek | C00002145 | 1 / 2 |
| P03956 | Interstitial collagenase | M10A | C00002145 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002145 | 0 / 0 |
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00002172 | 1 / 0 |
| Q9Y233 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | PDE_10A | C00025430 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00002150 | 1 / 1 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00002145 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00002145 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002150 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002145 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002145 | 0 / 0 |
| O14757 | Serine/threonine-protein kinase Chk1 | Chk1 | C00002145 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00002145 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002145 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002145 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00002146 | 2 / 2 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002145 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002145 | 2 / 0 |
| P09651 | Heterogeneous nuclear ribonucleoprotein A1 | Unclassified protein | C00002145 | 0 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002145 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002145 | 1 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002145 | 1 / 2 |
| P16083 | Ribosyldihydronicotinamide dehydrogenase [quinone] | Enzyme | C00002146 | 0 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00002145 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002145 | 0 / 1 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002145 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002145 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002145 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00002145 | 1 / 1 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002145 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002145 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002145 | 2 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002145 | 1 / 1 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00002145 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00002145 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002145 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00002145 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00002145 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002145 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00026394 | 2 / 2 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00002145 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00002145 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002145 | 1 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00002145 | 6 / 4 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002145 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002145 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00002145 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002145 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00002145 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00002145 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002145 | 0 / 0 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00002145 | 4 / 4 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002145 | 1 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00002145 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002145 | 1 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00001766 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002145 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002145 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002145 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002145 | 2 / 1 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002145 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002177 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002145 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00002145 | 1 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00002145 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002200 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002145 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002145 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002145 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00002145 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002145 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002145 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002145 | 0 / 1 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00002145 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002145 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002145 | 0 / 0 |
| O14746 | Telomerase reverse transcriptase | Enzyme | C00002145 | 5 / 5 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00002145 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00001766 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002145 | 0 / 0 |
| Q2TB90 | Putative hexokinase HKDC1 | Enzyme | C00002150 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002145 | 2 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00002145 | 2 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002145 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002145 | 1 / 8 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002145 | 0 / 0 |
| Q9HBX9 | Relaxin receptor 1 | Relaxin receptor | C00002145 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002145 | 0 / 0 |
| Q00653 | Nuclear factor NF-kappa-B p100 subunit | Transcription Factor | C00002152 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00002152 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002145 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002145 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002145 | 0 / 0 |
| P30874 | Somatostatin receptor type 2 | Somatostatin receptor | C00002145 | 0 / 0 |
| P31391 | Somatostatin receptor type 4 | Somatostatin receptor | C00002145 | 0 / 0 |
| P32745 | Somatostatin receptor type 3 | Somatostatin receptor | C00002145 | 0 / 0 |
| P35346 | Somatostatin receptor type 5 | Somatostatin receptor | C00002145 | 0 / 0 |
| P30872 | Somatostatin receptor type 1 | Somatostatin receptor | C00002145 | 0 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00002145 | 0 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00002142 | 0 / 3 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00002150 | 2 / 1 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002145 | 0 / 0 |
113 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00002145
C00002193
C00002200
C00031117
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001766
C00002193
C00031117
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00002145
C00002193
C00031117
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001766
C00002193
C00031117
|
| 338567 | KCNK18, K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK | potassium channel, subfamily K, member 18 |
C00002193
C00031117
|
| 6582 | SLC22A2, OCT2 | solute carrier family 22 (organic cation transporter), member 2 |
C00002193
C00031117
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002145
C00002200
|
| 6580 | SLC22A1, HOCT1, OCT1, oct1_cds | solute carrier family 22 (organic cation transporter), member 1 |
C00002193
C00031117
|
| 3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00002193
C00031117
|
| 2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00002193
C00031117
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00002193
C00031117
|
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00002193
C00031117
|
| 6581 | SLC22A3, EMT, EMTH, OCT3 | solute carrier family 22 (organic cation transporter), member 3 |
C00002193
C00031117
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002145
C00031117
|
| 148 | ADRA1A, ADRA1C, ADRA1L1, ALPHA1AAR | adrenoceptor alpha 1A |
C00031117
|
| 672 | BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53 | breast cancer 1, early onset |
C00002145
|
| 675 | BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2 | breast cancer 2, early onset |
C00002145
|
| 51719 | CAB39, MO25 | calcium binding protein 39 |
C00002145
|
| 835 | CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57 | caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55) |
C00002145
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002145
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00002145
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00002145
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002145
|
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 |
C00002145
|
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00002145
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00002145
|
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00002145
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00002145
|
| 634 | CEACAM1, BGP, BGP1, BGPI | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
C00002145
|
| 10153 | CEBPZ, CBF, CBF2, HSP-CBF, NOC1 | CCAAT/enhancer binding protein (C/EBP), zeta |
C00002145
|
| 1508 | CTSB, APPS, CPSB | cathepsin B (EC:3.4.22.1) |
C00002145
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002145
|
| 1806 | DPYD, DHP, DHPDHASE, DPD | dihydropyrimidine dehydrogenase (EC:1.3.1.2) |
C00002145
|
| 9538 | EI24, EPG4, PIG8, TP53I8 | etoposide induced 2.4 |
C00002145
|
| 2033 | EP300, KAT3B, RSTS2, p300 | E1A binding protein p300 (EC:2.3.1.48) |
C00002145
|
| 9852 | EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
C00002145
|
| 2067 | ERCC1, COFS4, RAD10, UV20 | excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) |
C00002145
|
| 2072 | ERCC4, ERCC11, FANCQ, RAD1, XPF | excision repair cross-complementing rodent repair deficiency, complementation group 4 |
C00002145
|
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor |
C00002145
|
| 2232 | FDXR, ADXR | ferredoxin reductase (EC:1.18.1.6) |
C00002145
|
| 2395 | FXN, CyaY, FA, FARR, FRDA, X25 | frataxin (EC:1.16.3.1) |
C00002145
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002145
|
| 3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00002145
|
| 3183 | HNRNPC, C1, C2, HNRNP, HNRPC, SNRPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) |
C00002145
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00002145
|
| 3570 | IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80 | interleukin 6 receptor |
C00002145
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002145
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00002145
|
| 3956 | LGALS1, GAL1, GBP | lectin, galactoside-binding, soluble, 1 |
C00002145
|
| 5606 | MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2 | mitogen-activated protein kinase kinase 3 (EC:2.7.12.2) |
C00002145
|
| 4217 | MAP3K5, ASK1, MAPKKK5, MEKK5 | mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25) |
C00002145
|
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00002145
|
| 4137 | MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU | microtubule-associated protein tau |
C00002145
|
| 4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00002145
|
| 4255 | MGMT | O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) |
C00002145
|
| 406929 | MIR138-1, MIRN138-1 | microRNA 138-1 |
C00002145
|
| 8440 | NCK2, GRB4, NCKbeta | NCK adaptor protein 2 |
C00002145
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002145
|
| 1263 | PLK3, CNK, FNK, PRK | polo-like kinase 3 (EC:2.7.11.21) |
C00002145
|
| 84152 | PPP1R1B, DARPP-32, DARPP32 | protein phosphatase 1, regulatory (inhibitor) subunit 1B (EC:3.1.3.16) |
C00002145
|
| 9055 | PRC1, ASE1 | protein regulator of cytokinesis 1 |
C00002145
|
| 5888 | RAD51, BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA | RAD51 recombinase |
C00002145
|
| 5889 | RAD51C, BROVCA3, FANCO, R51H3, RAD51L2 | RAD51 paralog C |
C00002145
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002145
|
| 5933 | RBL1, CP107, PRB1, p107 | retinoblastoma-like 1 (p107) |
C00002145
|
| 5934 | RBL2, P130, Rb2 | retinoblastoma-like 2 (p130) |
C00002145
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002145
|
| 6382 | SDC1, CD138, SDC, SYND1, syndecan | syndecan 1 |
C00002145
|
| 6606 | SMN1, BCD541, GEMIN1, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMNT, T-BCD541, TDRD16A | survival of motor neuron 1, telomeric |
C00002145
|
| 55512 | SMPD3, NSMASE2 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) (EC:3.1.4.12) |
C00002145
|
| 6667 | SP1 | Sp1 transcription factor |
C00002145
|
| 6670 | SP3, SPR2 | Sp3 transcription factor |
C00002145
|
| 6890 | TAP1, ABC17, ABCB2, APT1, D6S114E, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
C00002145
|
| 30851 | TAX1BP3, TIP-1 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
C00002145
|
| 55775 | TDP1 | tyrosyl-DNA phosphodiesterase 1 (EC:3.1.4.-) |
C00002145
|
| 7057 | THBS1, THBS, THBS-1, TSP, TSP-1, TSP1 | thrombospondin 1 |
C00002145
|
| 8744 | TNFSF9, 4-1BB-L, CD137L | tumor necrosis factor (ligand) superfamily, member 9 |
C00002145
|
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) |
C00002145
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00002145
|
| 11257 | TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1 | TP53 target 1 (non-protein coding) |
C00002145
|
| 7298 | TYMS, HST422, TMS, TS | thymidylate synthetase (EC:2.1.1.45) |
C00002145
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00002145
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00002145
|
| 7518 | XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
C00002145
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00002145
|
| 147 | ADRA1B, ADRA1, ALPHA1BAR | adrenoceptor alpha 1B |
C00031117
|
| 146 | ADRA1D, ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2 | adrenoceptor alpha 1D |
C00031117
|
| 440 | ASNS, TS11 | asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) |
C00031117
|
| 11067 | C10orf10, DEPP, FIG | chromosome 10 open reading frame 10 |
C00031117
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002145
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00031117
|
| 307 | ANXA4, ANX4, PIG28, ZAP36 | annexin A4 |
C00002145
|
| 2168 | FABP1, FABPL, L-FABP | fatty acid binding protein 1, liver |
C00031117
|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00002145
|
| 3479 | IGF1, IGF-I, IGF1A, IGFI | insulin-like growth factor 1 (somatomedin C) |
C00031117
|
| 83729 | INHBE | inhibin, beta E |
C00031117
|
| 3756 | KCNH1, EAG, EAG1, Kv10.1, h-eag | potassium voltage-gated channel, subfamily H (eag-related), member 1 |
C00031117
|
| 375790 | AGRN | agrin |
C00002145
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00002145
|
| 26471 | NUPR1, COM1, P8 | nuclear protein, transcriptional regulator, 1 |
C00031117
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001766
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00001766
|
| 57491 | AHRR, AHH, AHHR, bHLHe77 | aryl-hydrocarbon receptor repressor |
C00001766
|
| 6515 | SLC2A3, GLUT3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
C00031117
|
| 55244 | SLC47A1, MATE1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
C00031117
|
| 6876 | TAGLN, SM22, SMCC, TAGLN1, WS3-10 | transgelin |
C00031117
|
| 943 | TNFRSF8, CD30, D1S166E, Ki-1 | tumor necrosis factor receptor superfamily, member 8 |
C00031117
|
| 351 | APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 | amyloid beta (A4) precursor protein |
C00002193
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00002193
|
| 3552 | IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 | interleukin 1, alpha |
C00002193
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00002193
|
| 84679 | SLC9A7, NHE-7, NHE7, SLC9A6 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
C00002193
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002193
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (168)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #609135 | Aplastic anemia |
O14746
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #614022 | Atrial fibrillation, familial, 10; atfb10 |
Q14524
|
| #612240 | Atrial fibrillation, familial, 7; atfb7 |
P22460
|
| #108770 | Atrial standstill |
Q14524
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #601144 | Brugada syndrome 1; brgda1 |
Q14524
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #601154 | Cardiomyopathy, dilated, 1e; cmd1e |
Q14524
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #212140 | Carnitine deficiency, systemic primary; cdsp |
O76082
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #605479 | Cholestasis, benign recurrent intrahepatic, 2; bric2 |
O95342
|
| #601847 | Cholestasis, progressive familial intrahepatic, 2; pfic2 |
O95342
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #123400 | Creutzfeldt-jakob disease; cjd |
P04156
|
| #162800 | Cyclic neutropenia |
P08246
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P35498
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #613989 | Dyskeratosis congenita, autosomal dominant, 2; dkca2 |
O14746
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #613721 | Epileptic encephalopathy, early infantile, 11; eiee11 |
Q99250
|
| #226980 | Epiphyseal dysplasia, multiple, with early-onset diabetes mellitus |
Q9NZJ5
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600072 | Fatal familial insomnia; ffi |
P04156
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #604403 | Generalized epilepsy with febrile seizures plus, type 2; gefsp2 |
P35498
|
| #137440 | Gerstmann-straussler disease; gsd |
P04156
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #140700 | Heinz body anemias |
P68871
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #603218 | Huntington disease-like 1; hdl1 |
P04156
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #245300 | Kuru, susceptibility to |
P04156
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #603830 | Long qt syndrome 3; lqt3 |
Q14524
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #615134 | Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 |
O14746
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #609634 | Migraine, familial hemiplegic, 3; fhm3 |
P35498
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay |
P55789
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #113900 | Progressive familial heart block, type ia; pfhb1a |
Q14524
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #614742 | Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 |
O14746
|
| #178500 | Pulmonary fibrosis, idiopathic; ipf |
O14746
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #180300 | Rheumatoid arthritis; ra |
Q9H015
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #607745 | Seizures, benign familial infantile, 3; bfis3 |
Q99250
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #608567 | Sick sinus syndrome 1, autosomal recessive; sss1 |
Q14524
|
| #603903 | Sickle cell anemia |
P68871
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #606688 | Spongiform encephalopathy with neuropsychiatric features |
P04156
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #272120 | Sudden infant death syndrome |
Q14524
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #603829 | Ventricular fibrillation during myocardial infarction, susceptibility to |
Q14524
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (135)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00764 | Cri du chat syndrome |
O14746
(related)
|
| H01132 | Aplastic anemia (AA) |
O14746
(related)
|
| H01299 | Idiopathic pulmonary fibrosis |
O14746
(related)
|
| H00022 | Bladder cancer |
O14746
(marker)
P00533 (related) P04626 (related) P04637 (related) P68871 (marker) |
| H00024 | Prostate cancer |
O14746
(marker)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00286 | Crohn's disease |
O76082
(related)
Q9H015 (related) |
| H00525 | Disorders of fatty-acid oxidation |
O76082
(related)
|
| H00624 | Familial cholestasis |
O95342
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
P16473 (related) |
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
Q14524 (related) |
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00061 | Prion diseases |
P04156
(related)
|
| H01243 | Huntington's disease-like syndrome |
P04156
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P68871 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00731 | Atrial fibrillation |
P22460
(related)
Q14524 (related) |
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00775 | Familial or sporadic hemiplegic migraine |
P35498
(related)
|
| H00783 | Febrile seizures |
P35498
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
Q14524 (related) |
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00728 | Brugada syndrome (BRS) |
Q14524
(related)
|
| H00729 | Sick sinus syndrome (SSS) |
Q14524
(related)
|
| H00730 | Familial idiopathic ventricular fibrillation |
Q14524
(related)
|
| H01263 | Progressive cardiac conduction defect (PCCD) |
Q14524
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|
| H00606 | Early infantile epileptic encephalopathy |
Q99250
(related)
|
| H00806 | Benign familial neonatal and infantile epilepsies |
Q99250
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00512 | Permanent neonatal diabetes mellitus (PNDM) |
Q9NZJ5
(related)
|
| H00766 | Wolcott-Rallison syndrome |
Q9NZJ5
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
147 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D006099 | Granuloma |
C00002173
C00031117 C00002193 |
| D006505 | Hepatitis |
C00002173
C00031117 C00002193 |
| D000380 | Agranulocytosis |
C00031117
C00002193 |
| D014786 | Vision Disorders |
C00031117
C00002193 |
| D003967 | Diarrhea |
C00002145
C00031117 |
| D018879 | Ventricular Premature Complexes |
C00031117
C00002193 |
| D014693 | Ventricular Fibrillation |
C00031117
C00002193 |
| D014657 | Vasculitis |
C00031117
C00002193 |
| D016171 | Torsades de Pointes |
C00031117
C00002193 |
| D013921 | Thrombocytopenia |
C00031117
C00002193 |
| D013610 | Tachycardia |
C00031117
C00002193 |
| D013575 | Syncope |
C00031117
C00002193 |
| D011618 | Psychotic Disorders |
C00031117
C00002193 |
| D009503 | Neutropenia |
C00002145
C00002193 |
| D010787 | Photosensitivity Disorders |
C00031117
C00002193 |
| D058186 | Acute Kidney Injury |
C00031117
C00002193 |
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00002173
C00031117 |
| D016778 | Malaria, Falciparum |
C00031117
C00002193 |
| D000743 | Anemia, Hemolytic |
C00031117
C00002193 |
| D008288 | Malaria |
C00031117
C00002193 |
| D001145 | Arrhythmias, Cardiac |
C00031117
C00002193 |
| D008133 | Long QT Syndrome |
C00031117
C00002193 |
| D007024 | Hypotension, Orthostatic |
C00031117
C00002193 |
| D007022 | Hypotension |
C00031117
C00002193 |
| D054537 | Atrioventricular Block |
C00031117
C00002193 |
| D001919 | Bradycardia |
C00031117
C00002193 |
| D007008 | Hypokalemia |
C00031117
C00002193 |
| D034381 | Hearing Loss |
C00031117
C00002193 |
| D005334 | Fever |
C00031117
C00002193 |
| D056486 | Drug-Induced Liver Injury |
C00031117
C00002193 |
| D003875 | Drug Eruptions |
C00031117
C00002193 |
| D003638 | Deafness |
C00031117
C00002193 |
| D062787 | Drug Overdose |
C00002193
|
| D003324 | Coronary Artery Disease |
C00031117
|
| D016757 | Death, Sudden, Cardiac |
C00031117
|
| D003693 | Delirium |
C00031117
|
| D003704 | Dementia |
C00031117
|
| D003117 | Color Vision Defects |
C00031117
|
| D004342 | Drug Hypersensitivity |
C00031117
|
| D003072 | Cognition Disorders |
C00031117
|
| D005076 | Exanthema |
C00031117
|
| D015267 | Churg-Strauss Syndrome |
C00031117
|
| D005767 | Gastrointestinal Diseases |
C00031117
|
| D002779 | Cholestasis |
C00031117
|
| D006323 | Heart Arrest |
C00031117
|
| D006327 | Heart Block |
C00031117
|
| D006333 | Heart Failure |
C00031117
|
| D006417 | Hematuria |
C00031117
|
| D006529 | Hepatomegaly |
C00031117
|
| D002493 | Central Nervous System Diseases |
C00031117
|
| D001282 | Atrial Flutter |
C00031117
|
| D001281 | Atrial Fibrillation |
C00031117
|
| D007674 | Kidney Diseases |
C00031117
|
| D007970 | Leukopenia |
C00031117
|
| D054068 | Livedo Reticularis |
C00031117
|
| D001168 | Arthritis |
C00031117
|
| D008180 | Lupus Erythematosus, Systemic |
C00031117
|
| D008181 | Lupus Nephritis |
C00031117
|
| D008206 | Lymphatic Diseases |
C00031117
|
| D000744 | Anemia, Hemolytic, Autoimmune |
C00031117
|
| D000741 | Anemia, Aplastic |
C00031117
|
| D019964 | Mood Disorders |
C00031117
|
| D009103 | Multiple Sclerosis |
C00031117
|
| D018908 | Muscle Weakness |
C00031117
|
| D009325 | Nausea |
C00031117
|
| D009404 | Nephrotic Syndrome |
C00031117
|
| D019954 | Neurobehavioral Manifestations |
C00031117
|
| D010259 | Paranoid Disorders |
C00031117
|
| D010291 | Paresis |
C00031117
|
| D024801 | Tauopathies |
C00002145
|
| D009374 | Neoplasms, Experimental |
C00002145
|
| D011693 | Purpura |
C00031117
|
| D011695 | Purpura, Schoenlein-Henoch |
C00031117
|
| D011696 | Purpura, Thrombocytopenic |
C00031117
|
| D012131 | Respiratory Insufficiency |
C00031117
|
| D012848 | Sinoatrial Block |
C00031117
|
| D054138 | Sinus Arrest, Cardiac |
C00031117
|
| D013163 | Splenomegaly |
C00031117
|
| D009369 | Neoplasms |
C00002145
|
| D007968 | Leukoencephalopathy, Progressive Multifocal |
C00002145
|
| D013617 | Tachycardia, Supraventricular |
C00031117
|
| D017180 | Tachycardia, Ventricular |
C00031117
|
| D007945 | Leukemia, Lymphoid |
C00002145
|
| D006816 | Huntington Disease |
C00002145
|
| D014581 | Urticaria |
C00031117
|
| D014605 | Uveitis |
C00031117
|
| D018316 | Gliosarcoma |
C00002145
|
| D018366 | Vasculitis, Leukocytoclastic, Cutaneous |
C00031117
|
| D018754 | Ventricular Dysfunction |
C00031117
|
| D005910 | Glioma |
C00002145
|
| D054141 | Ventricular Flutter |
C00031117
|
| D005621 | Friedreich Ataxia |
C00002145
|
| D007565 | Jaundice |
C00002173
|
| D014927 | Wolff-Parkinson-White Syndrome |
C00031117
|
| D015746 | Abdominal Pain |
C00002193
|
| D000014 | Abnormalities, Drug-Induced |
C00002193
|
| D000550 | Amblyopia |
C00002193
|
| D000855 | Anorexia |
C00002193
|
| D001008 | Anxiety Disorders |
C00002193
|
| D001766 | Blindness |
C00002193
|
| D001943 | Breast Neoplasms |
C00002193
|
| D002637 | Chest Pain |
C00002193
|
| D016770 | Ciliophora Infections |
C00002193
|
| D003128 | COMA |
C00002193
|
| D003221 | Confusion |
C00002193
|
| D003872 | Dermatitis |
C00002193
|
| D004195 | Disease Models, Animal |
C00002193
|
| D004211 | Disseminated Intravascular Coagulation |
C00002193
|
| D004244 | Dizziness |
C00002193
|
| D023921 | Coronary Stenosis |
C00031117
|
| D004417 | Dyspnea |
C00002193
|
| D004421 | Dystonia |
C00002193
|
| D004830 | Epilepsy, Tonic-Clonic |
C00002193
|
| D005315 | Fetal Diseases |
C00002193
|
| D005393 | Fish Diseases |
C00002193
|
| D006261 | Headache |
C00002193
|
| D006311 | Hearing Disorders |
C00002193
|
| D006319 | Hearing Loss, Sensorineural |
C00002193
|
| D006331 | Heart Diseases |
C00002193
|
| D006461 | Hemolysis |
C00002193
|
| D006463 | Hemolytic-Uremic Syndrome |
C00002193
|
| D006470 | Hemorrhage |
C00002193
|
| D006948 | Hyperkinesis |
C00002193
|
| D007673 | Kidney Cortex Necrosis |
C00002193
|
| D008269 | Macular Edema |
C00002193
|
| D016779 | Malaria, Cerebral |
C00002193
|
| D009120 | Muscle Cramp |
C00002193
|
| D009224 | Myotonia Congenita |
C00002193
|
| D009336 | Necrosis |
C00002193
|
| D009395 | Nephritis, Interstitial |
C00002193
|
| D009468 | Neuromuscular Diseases |
C00002193
|
| D009896 | Optic Atrophy |
C00002193
|
| D009901 | Optic Nerve Diseases |
C00002193
|
| D010146 | Pain |
C00002193
|
| D010198 | Pancytopenia |
C00002193
|
| D018512 | Parasitemia |
C00002193
|
| D011041 | Poisoning |
C00002193
|
| D011697 | Purpura, Thrombotic Thrombocytopenic |
C00002193
|
| D051437 | Renal Insufficiency |
C00002193
|
| D012164 | Retinal Diseases |
C00002193
|
| D012206 | Rhabdomyolysis |
C00002193
|
| D012640 | Seizures |
C00002193
|
| D020922 | Sleep-Wake Transition Disorders |
C00002193
|
| D057049 | Thrombotic Microangiopathies |
C00002193
|
| D014012 | Tinnitus |
C00002193
|
| D015845 | Tonic Pupil |
C00002193
|
| D014839 | Vomiting |
C00002193
|