KCF-S cluster No. 257 (25 metabolites)

Corresponding Phytochemical cluster No. 7

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (25)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	49
Magnoliophyta	1

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Cumulative family count

class name	count
Rutaceae	48
Notodontidae	1
Cucurbitaceae	1
Piperaceae	1

KEGG BRITE br08003

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Categories (2)

br08003 Category	# of metabolite
Acridone alkaloids	4
Quinoline alkaloids	1

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metabolites link (6)

br08003 Category	KEGG ID	KNApSAcK ID
Acridone alkaloids	C10643	C00002137
Acridone alkaloids	C10681	C00002163
Quinoline alkaloids	C10699	C00002176
Acridone alkaloids	C10722	C00002186
Acridone alkaloids	C10724	C00002187
Acridone alkaloids	C10681	C00024253

Metabolite list (25)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002137	Arborinine	CHEMBL349609	C022784	1 / 0 / 0
C00002163	Furofoline I
C00002176	Japonine
C00002186	Melicopicine	CHEMBL455628
C00002187	Melicopine	CHEMBL1876999		7 / 8 / 4
C00024230	1-Hydroxy-3-methoxy-N-methylacridone	CHEMBL1094824
C00024231	1-Hydroxy-N-methylacridone	CHEMBL1288799		3 / 5 / 4
C00024232	5-Hydroxyarborinine	CHEMBL1928574
C00024243	Buxifoliadine-F
C00024245	Buxifoliadine-H	CHEMBL465629
C00024248	Citrusamine
C00024249	Citrusinine I	CHEMBL451705	C062044	1 / 0 / 0
C00024250	Citrusinine II	CHEMBL465847		1 / 0 / 0
C00024251	Evoxanthine
C00024253	Furacridone
C00024254	Furoparadine
C00024264	Marshdine
C00024270	Normelicopicine	CHEMBL453816
C00024271	Normelicopidine
C00024272	Normelicopine
C00034360	1,3-Dimethoxy-N-methylacridone
C00034720	Tegerrardin A	CHEMBL1095073
C00035416	Toddaliopsin B
C00035417	Toddaliopsin C
C00035418	Toddaliopsin D

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O60911	Cathepsin L2	C1A	C00024249 C00024250	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002187	7 / 3
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002187	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002187	0 / 0
P42858	Huntingtin	Unclassified protein	C00024231	1 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002187	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00002137	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002187	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002187	1 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00024231	4 / 3
P11940	Polyadenylate-binding protein 1	Unclassified protein	C00002187	0 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00024231	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions