KCF-S cluster No. 600 (14 metabolites)

Corresponding Phytochemical cluster No. 7

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	36

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Cumulative family count

class name	count
Rutaceae	36
Notodontidae	3

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Quinoline alkaloids	2

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Quinoline alkaloids	C10670	C00002158
Quinoline alkaloids	C10718	C00002185

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002158	Evoxine / 7-(2,3-Dihydroxy-3-methyl-butyl)oxy-8-methyldictamnine	CHEMBL1317300 CHEMBL1395597 CHEMBL1416006		14 / 9 / 9
C00002185	Maculosine
C00026348	(-)-Isotecleoxine
C00026366	(+)-Tecleoxine / (+)-Tecleanatalensine A
C00026404	Anhydroevoxine / 7-(2,3-Epoxy-3-methylbutyl)oxy-8-methoxy-dictamnine
C00026426	Evolatine
C00026463	Nkolbisine / Montrifoline / (-)-Nkolbisine / (-)-Montrifoline
C00026464	Nigdenine
C00033572	Chlorodesnkolbisine / (+)-Chlorodesnkolbisine / 6-(2'-Hydroxy-3'-chloroprenyloxy)-4,7-dimethoxyfuroquinoline
C00033583	7-(2'-Hydroxy-3'-chloroprenyloxy)-4,8-dimethoxyfuroquinoline
C00034059	Methylnkolbisine
C00037236	Haplotubine
C00040137	Quinosuaveoline A / (-)-Quinosuaveoline A
C00040138	Quinosuaveoline B / (+)-Quinosuaveoline B	CHEMBL574554

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002158	1 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002158	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002158	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002158	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002158	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002158	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002158	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002158	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002158	2 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002158	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002158	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002158	0 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002158	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002158	1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions