PCIDB

KNApSAcK Metabolite C00001727

Metabolite

KNApSAcK Entry

id C00001727
Name Evodiamine
CAS RN 518-17-2
Standard InChI InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3/t18-/m0/s1
Standard InChI (Main Layer) InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3

Cluster

Phytochemical cluster No. 7
KCF-S cluster No. 7591

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL81925 CHEMBL486598

KEGG

By LinkDB C09187

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Rutaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Araliopsis tabouensis 23513 Rutaceae rosids Viridiplantae
Evodia rutaecarpa 354523 Rutaceae rosids Viridiplantae

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 CHEMBL486598 CHEMBL664421 (1)
0 / 0
P11387 DNA topoisomerase 1 Isomerase CHEMBL486598 CHEMBL2175077 (1) CHEMBL2175218 (1)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL81925 CHEMBL1794584 (1)
2 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 CHEMBL486598 CHEMBL663708 (1)
4 / 4
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL486598 CHEMBL663694 (1)
0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor CHEMBL486598 CHEMBL993916 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#614674 Periodic fever, menstrual cycle-dependent P08908
#604229 Peters anomaly Q16678

KEGG DISEASE (4)

KEGG disease name UniProt
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)