KCF-S cluster No. 1798 (5 metabolites)

Corresponding Phytochemical cluster No. 7

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Liliopsida	3
asterids	2
eudicotyledons	1
rosids	1

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Cumulative family count

class name	count
Aspergillaceae	3
Orchidaceae	3
Acanthaceae	1
Brassicaceae	1
Polygonaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Quinazoline alkaloids	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Quinazoline alkaloids	C10742	C00002200

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002200	Tryptanthrin / Tryptanthrine / Couroupitine A	CHEMBL306946	C046243	20 / 22 / 23	2 / 0
C00026251	Sclerotigenin / (+/-)-Sclerotigenin	CHEMBL490538
C00028055	Circumdatin C
C00028058	Circumdatin F / (-)-Circumdatin F
C00039983	Phaitanthrin C / (-)-Phaitanthrin C	CHEMBL452806

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002200	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002200	0 / 3
P02545	Prelamin-A/C	Unclassified protein	C00002200	11 / 10
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002200	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002200	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00002200	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00002200	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002200	0 / 0
P42858	Huntingtin	Unclassified protein	C00002200	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002200	2 / 0
O75496	Geminin	Unclassified protein	C00002200	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002200	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002200	1 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002200	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002200	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002200	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002200	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002200	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002200	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002200	0 / 0

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002200
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002200

Related Diseases

Diseases related to proteins in ChEMBL interactions