PCIDB

KNApSAcK Metabolite C00002150

Metabolite

KNApSAcK Entry

id C00002150
Name Deoxyvasicinone
CAS RN 530-53-0
Standard InChI InChI=1S/C11H10N2O/c14-11-8-4-1-2-5-9(8)12-10-6-3-7-13(10)11/h1-2,4-5H,3,6-7H2
Standard InChI (Main Layer) InChI=1S/C11H10N2O/c14-11-8-4-1-2-5-9(8)12-10-6-3-7-13(10)11/h1-2,4-5H,3,6-7H2

Cluster

Phytochemical cluster No. 7
KCF-S cluster No. 3142

Link

ChEMBL

By standard InChI CHEMBL456881
By standard InChI Main Layer CHEMBL456881

KEGG

By LinkDB C10659

CTD

By CAS RN C025696

Human Protein / Gene in interaction

25 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL456881 CHEMBL1741321 (1)
1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL456881 CHEMBL1738312 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL456881 CHEMBL2114784 (1)
1 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme CHEMBL456881 CHEMBL1614331 (1)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL456881 CHEMBL1741325 (1)
0 / 1
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL456881 CHEMBL1614166 (1)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL456881 CHEMBL1614458 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL456881 CHEMBL1794486 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL456881 CHEMBL1794569 (1)
1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein CHEMBL456881 CHEMBL1614280 (1) CHEMBL1794529 (1)
0 / 0
P06276 Cholinesterase Hydrolase CHEMBL456881 CHEMBL964572 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL456881 CHEMBL1741322 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL456881 CHEMBL1613910 (1) CHEMBL1614227 (1)
3 / 3
P22303 Acetylcholinesterase Hydrolase CHEMBL456881 CHEMBL964571 (1)
1 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL456881 CHEMBL1614240 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL456881 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL456881 CHEMBL1741324 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL456881 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL456881 CHEMBL1737991 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL456881 CHEMBL1613914 (1)
0 / 0
Q2TB90 Putative hexokinase HKDC1 Enzyme CHEMBL456881 CHEMBL1738319 (1) CHEMBL1738579 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL456881 CHEMBL1614364 (1) CHEMBL1738394 (1)
1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL456881 CHEMBL1963857 (1) CHEMBL1964002 (1)
1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL456881 CHEMBL2114738 (1)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL456881 CHEMBL2114796 (1)
2 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#114500 Colorectal cancer; crc Q14191
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (9)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)