PCIDB

Peganum nigellastrum

Species

KNApSAcK Entry

Organism name Peganum nigellastrum
Genus Peganum
Family Nitrariaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Peganum nigellastrum
Linked NCBI taxonomy ID 673036
Linked level species

Family

Family in NCBI taxonomy Nitrariaceae
ID 91851

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (14)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00037439 External link 512 Luotonin D
No. 438
C00037438 External link 512 Luotonin C
No. 438
C00037056 External link 512 Dihydrosinapyl ferulate
No. 1298
C00037052 External link 512 Dihydroconiferyl ferulate
No. 1298
C00001737 External link 512 Harmine
CHEMBL269538
D006247
150 / 45 / 26 3 / 5 No. 1889 No. 4
C00026383 External link 512 3-(Indol-3-yl)quinoline
/ 3-(1H-Indol-3-yl)quinoline
CHEMBL309116
3 / 8 / 8 No. 1963
C00002149 External link 512 Deoxypeganine
CHEMBL355821
C048835
1 / 1 / 0 No. 2365 No. 7
C00002191 External link 512 Peganine
/ Vasicine
/ (-)-Linarine
/ (-)-Peganine
/ (-)-Vasicine
CHEMBL1186527
CHEMBL1456364
CHEMBL2163791
C019592
3 / 2 / 3 No. 2365 No. 7
C00002202 External link 512 Vasicinone
CHEMBL1864065
C052548
1 / 0 / 0 No. 3142 No. 7
C00002150 External link 512 Deoxyvasicinone
CHEMBL456881
C025696
25 / 13 / 9 No. 3142 No. 7
C00026385 External link 512 NSC 136922
/ 3-Phenylquinoline
No. 3168
C00026384 External link 512 3-(4-Hydroxyphenyl)quinoline
CHEMBL407114
1 / 0 / 0 No. 3168
C00026454 External link 512 Luotonin F
CHEMBL19143
2 / 0 / 0 No. 6808
C00026247 External link 512 Luotonin E
CHEMBL18544
2 / 0 / 0 No. 8737

Human Protein / Gene in interactions

171 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P22303 Acetylcholinesterase Hydrolase C00001737 C00002149 C00002150 1 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001737 C00002150 3 / 3
P11388 DNA topoisomerase 2-alpha Isomerase C00026247 C00026454 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001737 C00002150 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002150 C00002202 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001737 C00002150 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001737 C00002150 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001737 C00002150 1 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00026247 C00026454 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001737 C00002150 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001737 C00002150 0 / 0
P06276 Cholinesterase Hydrolase C00002150 C00002191 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001737 C00002191 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001737 C00002150 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001737 C00002150 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001737 C00002150 0 / 1
Q86V86 Serine/threonine-protein kinase pim-3 Pim C00001737 0 / 0
P17252 Protein kinase C alpha type Alpha C00001737 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00001737 0 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 C00001737 0 / 0
Q8IWQ3 Serine/threonine-protein kinase BRSK2 CAMK serine/threonine protein kinase BRSK subfamily C00001737 0 / 0
P27448 MAP/microtubule affinity-regulating kinase 3 CAMK serine/threonine protein kinase MARK subfamily C00001737 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00002150 0 / 0
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00001737 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00001737 1 / 1
P28222 5-hydroxytryptamine receptor 1B Serotonin receptor C00001737 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00001737 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00001737 0 / 0
Q05513 Protein kinase C zeta type Iota C00001737 0 / 0
P47898 5-hydroxytryptamine receptor 5A Serotonin receptor C00001737 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00001737 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00001737 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00001737 0 / 0
P41240 Tyrosine-protein kinase CSK Csk C00001737 0 / 0
P23443 Ribosomal protein S6 kinase beta-1 p70 C00001737 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00001737 0 / 0
Q9UQB9 Aurora kinase C Aur C00001737 1 / 1
P49761 Dual specificity protein kinase CLK3 Clk C00001737 0 / 0
Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase MNK subfamily C00001737 0 / 0
Q9NQU5 Serine/threonine-protein kinase PAK 6 STE serine/threonine protein kinase PAKB subfamily C00001737 0 / 0
Q16644 MAP kinase-activated protein kinase 3 CAMK serine/threonine protein kinase MAPKAPK C00001737 0 / 0
Q9H422 Homeodomain-interacting protein kinase 3 CMGC dual-specificity kinase HIPK C00001737 0 / 0
Q14680 Maternal embryonic leucine zipper kinase Melk C00001737 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00001737 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00002150 1 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00026383 1 / 8
P11473 Vitamin D3 receptor NR1I1 C00002191 2 / 3
Q15746 Myosin light chain kinase, smooth muscle Mlck C00001737 1 / 1
Q13188 Serine/threonine-protein kinase 3 STE serine/threonine protein kinase MST subfamily C00001737 0 / 0
P31751 RAC-beta serine/threonine-protein kinase Akt C00001737 2 / 2
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily C00001737 0 / 0
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta Other serine/threonine protein kinase C00001737 0 / 0
Q16513 Serine/threonine-protein kinase N2 Pkn C00001737 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00001737 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001737 0 / 0
O15530 3-phosphoinositide-dependent protein kinase 1 Pdk1 C00001737 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00001737 2 / 2
Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 META serine/threonine protein kinase subfamily C00001737 0 / 0
Q9P286 Serine/threonine-protein kinase PAK 7 STE serine/threonine protein kinase PAKB subfamily C00001737 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001737 0 / 0
Q96SB4 SRSF protein kinase 1 Srpk C00001737 0 / 0
Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 CMGC dual-specificity kinase DYRK2 C00001737 0 / 0
O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 CMGC dual-specificity kinase DYRK2 C00001737 0 / 0
O96013 Serine/threonine-protein kinase PAK 4 STE serine/threonine protein kinase PAKB subfamily C00001737 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00001737 0 / 0
Q15759 Mitogen-activated protein kinase 11 p38 C00001737 0 / 0
Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B CMGC dual-specificity kinase DYRK1 C00001737 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001737 2 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00001737 0 / 0
P35348 Alpha-1A adrenergic receptor Adrenergic receptor C00001737 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00001737 0 / 0
Q15418 Ribosomal protein S6 kinase alpha-1 Rskb C00001737 0 / 0
O15264 Mitogen-activated protein kinase 13 p38 C00001737 0 / 0
P53779 Mitogen-activated protein kinase 10 Jnk C00001737 0 / 1
P51955 Serine/threonine-protein kinase Nek2 Nek C00001737 0 / 0
Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 META serine/threonine protein kinase subfamily C00001737 0 / 0
Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 CAMK serine/threonine protein kinase MNK subfamily C00001737 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00002150 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00002150 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001737 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00001737 2 / 0
P48730 Casein kinase I isoform delta Ck1 C00001737 1 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00001737 0 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00001737 0 / 0
Q96GD4 Aurora kinase B Aur C00001737 0 / 0
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK C00001737 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00001737 0 / 0
P45983 Mitogen-activated protein kinase 8 Jnk C00001737 0 / 0
Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 Enzyme C00001737 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00002150 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001737 2 / 2
Q8TF76 Serine/threonine-protein kinase haspin Haspin C00001737 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00001737 1 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001737 4 / 1
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00001737 0 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00001737 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00001737 0 / 0
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK C00001737 0 / 0
O75116 Rho-associated protein kinase 2 Rock C00001737 0 / 0
P07948 Tyrosine-protein kinase Lyn Src C00001737 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002150 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00001737 4 / 1
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily C00001737 0 / 0
P51812 Ribosomal protein S6 kinase alpha-3 Rskb C00001737 2 / 2
Q8TDX7 Serine/threonine-protein kinase Nek7 Nek C00001737 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00001737 0 / 0
Q9HAZ1 Dual specificity protein kinase CLK4 Clk C00001737 0 / 0
Q9HC98 Serine/threonine-protein kinase Nek6 Nek C00001737 0 / 0
Q9H2X6 Homeodomain-interacting protein kinase 2 CMGC dual-specificity kinase HIPK C00001737 0 / 0
P49759 Dual specificity protein kinase CLK1 Clk C00001737 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002150 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001737 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001737 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00001737 1 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00001737 1 / 1
P28221 5-hydroxytryptamine receptor 1D Serotonin receptor C00001737 0 / 0
P35368 Alpha-1B adrenergic receptor Adrenergic receptor C00001737 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00001737 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00001737 0 / 1
O96017 Serine/threonine-protein kinase Chk2 Rad53 C00001737 4 / 1
Q14012 Calcium/calmodulin-dependent protein kinase type 1 Camk1 C00001737 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00001737 0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00001737 1 / 0
P53778 Mitogen-activated protein kinase 12 p38 C00001737 0 / 0
O00418 Eukaryotic elongation factor 2 kinase Atypical serine/threonine protein kinase alpha subfamily C00001737 0 / 0
P49760 Dual specificity protein kinase CLK2 Clk C00001737 0 / 0
Q8TD08 Mitogen-activated protein kinase 15 Mapk C00001737 0 / 0
P45984 Mitogen-activated protein kinase 9 Jnk C00001737 0 / 0
Q9Y2I1 Nischarin Other cytosolic protein C00001737 0 / 0
Q2TB90 Putative hexokinase HKDC1 Enzyme C00002150 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002150 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002150 1 / 0
Q04759 Protein kinase C theta type Delta C00001737 0 / 1
Q02156 Protein kinase C epsilon type Eta C00001737 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00001737 0 / 0
Q05655 Protein kinase C delta type Delta C00001737 0 / 0
P05129 Protein kinase C gamma type Alpha C00001737 1 / 1
P05771 Protein kinase C beta type Alpha C00001737 0 / 0
P24723 Protein kinase C eta type Eta C00001737 1 / 0
P41743 Protein kinase C iota type Iota C00001737 0 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00001737 2 / 0
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00001737 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00001737 0 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00001737 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00001737 0 / 0
P51946 Cyclin-H Other cytosolic protein C00001737 0 / 0
P50613 Cyclin-dependent kinase 7 Cdk7 C00001737 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00001737 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00001737 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00001737 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00001737 0 / 0
P20248 Cyclin-A2 Other cytosolic protein C00001737 0 / 0
P78396 Cyclin-A1 Other cytosolic protein C00001737 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00026384 0 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00001737 1 / 1
P09619 Platelet-derived growth factor receptor beta Pdgfr C00026383 5 / 1
P16234 Platelet-derived growth factor receptor alpha Pdgfr C00026383 2 / 1
P68400 Casein kinase II subunit alpha Ck2 C00001737 0 / 0
P19784 Casein kinase II subunit alpha' Ck2 C00001737 0 / 0
P67870 Casein kinase II subunit beta REG serine/threonine protein kinase family C00001737 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001737 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00001737 0 / 0
P21918 D(1B) dopamine receptor Dopamine receptor C00001737 1 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00001737 2 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00001737 1 / 0
P46098 5-hydroxytryptamine receptor 3A NS C00001737 0 / 0
O95264 5-hydroxytryptamine receptor 3B NS C00001737 0 / 0
O60563 Cyclin-T1 Other cytosolic protein C00001737 0 / 0
P50750 Cyclin-dependent kinase 9 Cdk9 C00001737 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002150 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00002150 2 / 1

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001737
1859 DYRK1A, DYRK, DYRK1, HP86, MNB, MNBH, MRD7 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (EC:2.7.12.1) C00001737
4137 MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU microtubule-associated protein tau C00001737

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (60)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#103780 Alcohol dependence P08172
P14416
P31645
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#606798 Blepharospasm, benign essential P21918
#114480 Breast cancer O96017
P31749
#300615 Brunner syndrome P21397
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#303600 Coffin-lowry syndrome; cls P51812
#114500 Colorectal cancer; crc P31749
P84022
Q14191
#615109 Cowden syndrome 6; cws6 P31749
#125853 Diabetes mellitus, noninsulin-dependent; niddm P31751
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#606764 Gastrointestinal stromal tumor; gist P16234
#137800 Glioma susceptibility 1; glm1 O75874
#607685 Hypereosinophilic syndrome, idiopathic; hes P16234
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#240900 Hypoinsulinemic hypoglycemia with hemihypertrophy; hihghh P31751
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#601626 Leukemia, acute myeloid; aml P09619
#609265 Li-fraumeni syndrome 2; lfs2 O96017
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P00533
#608516 Major depressive disorder; mdd P08172
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300844 Mental retardation, x-linked 19; mrx19 P51812
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#159900 Myoclonic dystonia P14416
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259500 Osteogenic sarcoma O96017
#614674 Periodic fever, menstrual cycle-dependent P08908
#176807 Prostate cancer O96017
#176920 Proteus syndrome P31749
#607276 Resting heart rate, variation in P08588
#243060 Spermatogenic failure 5; spgf5 Q9UQB9
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#605361 Spinocerebellar ataxia 14; sca14 P05129
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P24723
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (39)

KEGG name UniProt
H00881 Li-Fraumeni syndrome O96017 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P09619 (related)
P16234 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
Q99700 (related)
Q9NUW8 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00036 Osteosarcoma P08684 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00027 Ovarian cancer P31751 (related)
H00420 Familial partial lipodystrophy (FPL) P31751 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P51812 (related)
Q99714 (related)
H00574 Coffin-Lowry syndrome (CLS) P51812 (related)
H00606 Early infantile epileptic encephalopathy P53779 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) Q15746 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H01282 Spermatogenic failure Q9UQB9 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00001737
D004409 Dyskinesia, Drug-Induced C00001737
D006212 Hallucinations C00001737
D010243 Paralysis C00001737
D014202 Tremor C00001737