| Organism name | Adhatoda vasica |
|---|---|
| Genus | Adhatoda |
| Family | Acanthaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Justicia adhatoda |
|---|---|
| Linked NCBI taxonomy ID | 141317 |
| Linked level | species |
| Family in NCBI taxonomy | Acanthaceae |
|---|---|
| ID | 4185 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00007183
|
4,2'-Dihydroxychalcone 4-glucoside
|
No. 36 | No. 13 |
|
||||
|
C00002201
|
Vasicinol
|
No. 2365 | No. 7 |
|
||||
|
C00002191
|
Peganine
/ Vasicine / (-)-Linarine / (-)-Peganine / (-)-Vasicine |
CHEMBL1186527
CHEMBL1456364 CHEMBL2163791 |
C019592
|
3 / 2 / 3 | No. 2365 | No. 7 |
|
|
|
C00002150
|
Deoxyvasicinone
|
CHEMBL456881
|
C025696
|
25 / 13 / 9 | No. 3142 | No. 7 |
|
|
|
C00002202
|
Vasicinone
|
CHEMBL1864065
|
C052548
|
1 / 0 / 0 | No. 3142 | No. 7 |
|
|
|
C00002134
|
Anisotine
|
No. 3956 | No. 7 |
|
||||
|
C00026249
|
Peganidine
|
No. 4807 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P06276 | Cholinesterase | Hydrolase | C00002150 C00002191 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002150 C00002202 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002150 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002150 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002150 | 0 / 1 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002150 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00002191 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002150 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002150 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002191 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00002150 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002150 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002150 | 1 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002150 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002150 | 3 / 3 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002150 | 1 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002150 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002150 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002150 | 0 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002150 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002150 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002150 | 0 / 0 |
| Q2TB90 | Putative hexokinase HKDC1 | Enzyme | C00002150 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002150 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002150 | 1 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002150 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00002150 | 2 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|