PCIDB

KNApSAcK Metabolite C00002159

Metabolite

KNApSAcK Entry

id C00002159
Name gamma-Fagarine / 4,8-Dimethoxyfuro[2,3-b]quinoline
CAS RN 524-15-2
Standard InChI InChI=1S/C13H11NO3/c1-15-10-5-3-4-8-11(10)14-13-9(6-7-17-13)12(8)16-2/h3-7H,1-2H3
Standard InChI (Main Layer) InChI=1S/C13H11NO3/c1-15-10-5-3-4-8-11(10)14-13-9(6-7-17-13)12(8)16-2/h3-7H,1-2H3

Cluster

Phytochemical cluster No. 7
KCF-S cluster No. 368

Link

ChEMBL

By standard InChI CHEMBL252925
By standard InChI Main Layer CHEMBL252925

KEGG

By LinkDB C10676

CTD

By CAS RN C049193

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL252925 CHEMBL1614166 (1)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL252925 CHEMBL1614458 (1)
0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme CHEMBL252925 CHEMBL2114807 (1)
4 / 2
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL252925 CHEMBL2114810 (1)
7 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL252925 CHEMBL1614038 (1)
2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL252925 CHEMBL1738588 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL252925 CHEMBL1613914 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL252925 CHEMBL1738442 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#119900 Digital clubbing, isolated congenital P15428
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#174800 Mccune-albright syndrome; mas P63092
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#166350 Osseous heteroplasia, progressive; poh P63092
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (7)

KEGG disease name UniProt
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)