Zanthoxylum ailanthoides
Species
KNApSAcK Entry
| Organism name | Zanthoxylum ailanthoides |
|---|---|
| Genus | Zanthoxylum |
| Family | Rutaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Zanthoxylum ailanthoides |
|---|---|
| Linked NCBI taxonomy ID | 159071 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (27)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001861
|
Glaucine
/ S-(+)-Glaucine / O,O-Dimethylisoboldine |
CHEMBL36536
CHEMBL228082 |
14 / 8 / 6 | No. 20 | No. 4 |
|
||
|
C00003738
|
beta-Amyrin
/ beta-Amirin / beta-Amyrine / beta-Amyrenol |
C036380
|
0 / 4 | No. 23 | No. 51 |
|
||
|
C00002631
|
(+)-Lirioresinol B
/ (+)-Syringaresinol |
CHEMBL361362
CHEMBL402653 |
C042192
|
1 / 0 / 0 | No. 38 | No. 21 |
|
|
|
C00007190
|
(+)-Pinoresinol
|
CHEMBL267963
CHEMBL487611 CHEMBL460862 |
C103298
|
7 / 5 / 6 | No. 38 | No. 21 |
|
|
|
C00007192
|
(+)-Epipinoresinol
|
CHEMBL267963
CHEMBL487611 CHEMBL460862 |
7 / 5 / 6 | No. 38 | No. 21 |
|
||
|
C00024654
|
Decarine
/ Rutaceline |
CHEMBL458702
|
No. 254 | No. 4 |
|
|||
|
C00024655
|
Norchelerythrine
/ O-Methyldecarine / N-Norchelerythrine / De-N-methylchelerythrine / Des-N-methylchelerythrine |
CHEMBL1182694
|
No. 254 | No. 4 |
|
|||
|
C00000604
|
(-)-Secoisolariciresinol
|
CHEMBL368347
|
C060283
|
2 / 1 / 1 | 1 / 0 | No. 282 | No. 21 |
|
|
C00002159
|
gamma-Fagarine
/ 4,8-Dimethoxyfuro[2,3-b]quinoline |
CHEMBL252925
|
C049193
|
8 / 14 / 7 | No. 368 | No. 7 |
|
|
|
C00026410
|
Confusameline
/ 7-Hydroxydictamnine / 7-O-Demethylevolitrine |
CHEMBL503574
|
No. 368 | No. 7 |
|
|||
|
C00047162
|
Ailanthamide
|
CHEMBL556469
|
No. 499 |
|
||||
|
C00007194
|
(+)-Episesamin
|
CHEMBL43469
CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861 |
20 / 24 / 15 | No. 621 | No. 21 |
|
||
|
C00002608
|
Hinokinin
/ Hinoquinin / (-)-Hinokinin / (-)-Hinoquinin |
CHEMBL180970
CHEMBL182073 CHEMBL242011 |
C475934
|
2 / 1 / 1 | No. 629 | No. 21 |
|
|
|
C00002505
|
Xanthyletin
|
CHEMBL303846
|
C020814
|
29 / 43 / 58 | No. 750 | No. 25 |
|
|
|
C00007558
|
Syringaldehyde
/ 4-Hydroxy-3,5-dimethoxybenzaldehyde |
CHEMBL225303
|
C069665
|
No. 856 |
|
|||
|
C00002498
|
Scoparone
/ 6,7-Dimethoxycoumarin / Aesculetin dimethyl ether |
CHEMBL325864
|
C018145
|
4 / 2 / 2 | 6 / 0 | No. 864 | No. 25 |
|
|
C00000575
|
Bergaptan
|
CHEMBL24171
|
C022909
|
22 / 22 / 17 | 0 / 3 | No. 1282 | No. 25 |
|
|
C00026361
|
Platydesmine
/ (+)-Platydesmine |
No. 1467 | No. 7 |
|
||||
|
C00002657
|
p-Formylphenol
/ 4-Hydroxybenzaldehyde / p-Hydroxybenzaldehyde |
CHEMBL14193
|
C011483
|
3 / 2 / 2 | No. 2076 |
|
||
|
C00030751
|
Methyl 4-hydroxybenzoate
|
CHEMBL325372
|
C015358
|
102 / 49 / 57 | 3 / 0 | No. 2169 |
|
|
|
C00033844
|
Evofolin B
/ (-)-Evofolin B |
CHEMBL448601
CHEMBL602133 |
No. 2211 |
|
||||
|
C00026423
|
Edulitine
/ Robustinin / Robustinine |
CHEMBL256497
|
No. 2421 | No. 7 |
|
|||
|
C00026442
|
Integriquinolone
|
No. 3424 |
|
|||||
|
C00047311
|
N-(4-Methoxyphenethyl)-N-methylbenzamide
|
CHEMBL551703
|
No. 4049 |
|
||||
|
C00047149
|
4-(4'-Hydroxy-3'-methylbutoxy)benzaldehyde
|
No. 5180 |
|
|||||
|
C00047163
|
Ailanthoidiol
|
No. 5180 |
|
|||||
|
C00047131
|
(2E,4E)-N-Isobutyl-6-oxohepta-2,4-dienamide
|
CHEMBL556470
|
No. 6978 |
|
Human Protein / Gene in interactions
158 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001861 C00002159 C00002505 C00007190 C00007192 C00007194 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000575 C00000604 C00002608 C00007194 C00030751 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000575 C00000604 C00002608 C00007194 C00030751 | 0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000575 C00001861 C00002159 C00002505 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000575 C00002159 C00002505 C00007194 | 7 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000575 C00001861 C00002159 C00002505 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000575 C00002505 C00007194 C00030751 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 C00007192 C00030751 | 0 / 3 |
| P56817 | Beta-secretase 1 | A1A | C00000575 C00002498 C00002505 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001861 C00002505 C00007194 | 4 / 3 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001861 C00007194 C00030751 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000575 C00002505 C00007194 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000575 C00007194 C00030751 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000575 C00001861 C00002505 | 3 / 3 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000575 C00007194 C00030751 | 0 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002159 C00002505 C00007194 | 2 / 2 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002505 C00030751 | 0 / 1 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002505 C00030751 | 1 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002505 C00030751 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 C00007192 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00007194 C00030751 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 C00007192 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 C00007192 | 5 / 3 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 C00007192 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002505 C00007194 | 4 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002505 C00007194 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002505 C00030751 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002159 C00002505 | 4 / 2 |
| O75496 | Geminin | Unclassified protein | C00001861 C00007194 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000575 C00030751 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002505 C00030751 | 1 / 2 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002505 C00030751 | 7 / 37 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002505 C00030751 | 1 / 2 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001861 C00002159 | 1 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 C00007192 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002498 C00030751 | 1 / 1 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00030751 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00030751 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00030751 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00030751 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00030751 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00030751 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00000575 | 1 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00030751 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00030751 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00030751 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00030751 | 0 / 1 |
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002498 | 1 / 1 |
| Q9BQF6 | Sentrin-specific protease 7 | Enzyme | C00001861 | 0 / 0 |
| Q9GZR1 | Sentrin-specific protease 6 | Enzyme | C00001861 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00030751 | 1 / 8 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00002631 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00007194 | 2 / 3 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00030751 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00030751 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00030751 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00030751 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00030751 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00030751 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00030751 | 0 / 0 |
| P16389 | Potassium voltage-gated channel subfamily A member 2 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00030751 | 1 / 1 |
| Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001861 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00007194 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00030751 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00030751 | 1 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00030751 | 0 / 0 |
| P42574 | Caspase-3 | C14 | C00001861 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002505 | 2 / 2 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002657 | 1 / 1 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00030751 | 1 / 1 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00002657 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00007194 | 2 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000575 | 3 / 2 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002505 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00030751 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002505 | 4 / 2 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00030751 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00030751 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00030751 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00030751 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00030751 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00030751 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00030751 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00030751 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00030751 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00030751 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00030751 | 1 / 0 |
| Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00001861 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00030751 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00030751 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00030751 | 1 / 0 |
| P17658 | Potassium voltage-gated channel subfamily A member 6 | K | C00000575 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00030751 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00030751 | 0 / 0 |
| P20813 | Cytochrome P450 2B6 | Cytochrome P450 2B6 | C00000575 | 1 / 0 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002505 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00007194 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00030751 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00030751 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00030751 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00030751 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00030751 | 2 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00030751 | 2 / 2 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00002657 | 1 / 1 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00030751 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00030751 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00030751 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00030751 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00030751 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00030751 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00030751 | 1 / 0 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002505 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00030751 | 2 / 1 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00030751 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00030751 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00030751 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00030751 | 0 / 0 |
| P22001 | Potassium voltage-gated channel subfamily A member 3 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002505 | 1 / 1 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00030751 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00030751 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00030751 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00030751 | 1 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00002505 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00030751 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00030751 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00030751 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00030751 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00030751 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00030751 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00030751 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00030751 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00030751 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00030751 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00030751 | 2 / 1 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00030751 | 5 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00030751 | 2 / 2 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00030751 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00030751 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000575 | 3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00030751 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00030751 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00030751 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002505 | 1 / 1 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00030751 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00030751 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00030751 | 0 / 1 |
| P22460 | Potassium voltage-gated channel subfamily A member 5 | KCNA, Kv1.x (Shaker) | C00000575 | 1 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00030751 | 0 / 0 |
| P48547 | Potassium voltage-gated channel subfamily C member 1 | K | C00000575 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002159 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002505 | 1 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00002498 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00030751 | 0 / 0 |
| Q09470 | Potassium voltage-gated channel subfamily A member 1 | KCNA, Kv1.x (Shaker) | C00000575 | 1 / 1 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00001861 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00007194 | 1 / 1 |
10 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00030751
|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00030751
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00030751
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002498
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002498
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00002498
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002498
|
| 5966 | REL, C-Rel | v-rel avian reticuloendotheliosis viral oncogene homolog |
C00002498
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002498
|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00000604
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (102)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #610251 | Alcohol sensitivity, acute |
P05091
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #612240 | Atrial fibrillation, familial, 7; atfb7 |
P22460
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #162800 | Cyclic neutropenia |
P08246
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #614546 | Efavirenz, poor metabolism of |
P20813
|
| #160120 | Episodic ataxia, type 1; ea1 |
Q09470
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (90)
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H01071 | Acute alcohol sensitivity |
P05091
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00731 | Atrial fibrillation |
P22460
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00749 | Episodic ataxias |
Q09470
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|