KCF-S cluster No. 2882 (4 metabolites)

Corresponding Phytochemical cluster No. 7

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	9
Liliopsida	6

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Cumulative family count

class name	count
Rutaceae	9
Amaryllidaceae	6

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Quinoline alkaloids	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Quinoline alkaloids	C10661	C00002152

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002152	Dubamine	CHEMBL502774		20 / 38 / 55
C00026493	Toddaquinoline	CHEMBL470880
C00029148	Trispheridine / Trisphaeridine	CHEMBL511443	C462033	1 / 0 / 0
C00046757	Graveolinine	CHEMBL2205100

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04637	Cellular tumor antigen p53	Transcription Factor	C00002152	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00002152	4 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002152	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002152	11 / 10
P11387	DNA topoisomerase 1	Isomerase	C00029148	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002152	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002152	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002152	4 / 2
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002152	7 / 3
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002152	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002152	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002152	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002152	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002152	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002152	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002152	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002152	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002152	0 / 0
Q00653	Nuclear factor NF-kappa-B p100 subunit	Transcription Factor	C00002152	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00002152	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00002152	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions