PCIDB

KNApSAcK Metabolite C00004653

Metabolite

KNApSAcK Entry

id C00004653
Name Retusine / Retusin(Ariocarpus) / Quercetin 3,7,3',4'-tetramethyl ether / 5-Hydroxy-3,7,3',4'-tetramethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one
CAS RN 1245-15-4
Standard InChI InChI=1S/C19H18O7/c1-22-11-8-12(20)16-15(9-11)26-18(19(25-4)17(16)21)10-5-6-13(23-2)14(7-10)24-3/h5-9,20H,1-4H3
Standard InChI (Main Layer) InChI=1S/C19H18O7/c1-22-11-8-12(20)16-15(9-11)26-18(19(25-4)17(16)21)10-5-6-13(23-2)14(7-10)24-3/h5-9,20H,1-4H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 8

Link

ChEMBL

By standard InChI CHEMBL77966
By standard InChI Main Layer CHEMBL77966

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 11
asterids 11
eudicotyledons 3
Liliopsida 3
Spermatophyta 1

Family (Top 10)

family name count
Asteraceae 9
Zingiberaceae 2
Rutaceae 2
Cunoniaceae 2
Orchidaceae 1
Solanaceae 1
Pteromalidae 1
Nyctaginaceae 1
Boraginaceae 1
Cactaceae 1

List (30)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Aeonium lindleyi 111153 Crassulaceae eudicotyledons Viridiplantae
Aframomum giganteum 188478 Zingiberaceae Liliopsida Viridiplantae
Amomum koenigii 252851 Zingiberaceae Liliopsida Viridiplantae
Ariocarpus retusus 130095 Cactaceae eudicotyledons Viridiplantae
Artemisia annua 35608 Asteraceae asterids Viridiplantae
Artemisia rupestris 86317 Asteraceae asterids Viridiplantae
Betula nigra 3508 Betulaceae rosids Viridiplantae
Brickellia eupatorioides 102754 Asteraceae asterids Viridiplantae
Bridelia ferruginea 319147 Phyllanthaceae rosids Viridiplantae
Cordia multispicata 79331 Boraginaceae asterids Viridiplantae
Cryptomeria japonica 3369 Cupressaceae Spermatophyta Viridiplantae
Dalbergia retusa 466221 Fabaceae rosids Viridiplantae
Eucryphia lucida 3791 Cunoniaceae rosids Viridiplantae
Eucryphia milliganii 85203 Cunoniaceae rosids Viridiplantae
Evodia merrillii 354493 Rutaceae rosids Viridiplantae
Geranium macrorrhizum L. 28963 Geraniaceae rosids Viridiplantae
Grindelia nana 381998 Asteraceae asterids Viridiplantae
Grindelia tenella 71045 Asteraceae asterids Viridiplantae
Larrea cuneifolia 108398 Zygophyllaceae rosids Viridiplantae
Macaranga triloba 109851 Euphorbiaceae rosids Viridiplantae
Melicope semecarpifolia 697038 Rutaceae rosids Viridiplantae
Mirabilis viscosa 3537 Nyctaginaceae eudicotyledons Viridiplantae
Nothofagus cunninghamii 28938 Nothofagaceae rosids Viridiplantae
Parthenium spp. 35934 Asteraceae asterids Viridiplantae
Siegesbeckia jorullensis 185190 Asteraceae asterids Viridiplantae
Siegesbeckia orientalis 185191 Asteraceae asterids Viridiplantae
Solanum paludosum 744103 Solanaceae asterids Viridiplantae
Spiranthes australis (R.BROWN) LINDL. 38214 Orchidaceae Liliopsida Viridiplantae
Urolepis hecatantha 51947 Pteromalidae Metazoa
Xanthocephalum gymnospermoides 71103 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs CHEMBL77966 CHEMBL1687517 (1) CHEMBL2045961 (1)
0 / 0
P08183 Multidrug resistance protein 1 drug CHEMBL77966 CHEMBL1687396 (1)
1 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL77966 CHEMBL1687393 (1) CHEMBL1687394 (1)
CHEMBL2045959 (1) CHEMBL2045960 (1)
2 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
#612244 Inflammatory bowel disease 13; ibd13 P08183
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0