Artemisia annua

• Index
• Plant Species
• Metabolite list (86)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Artemisia annua
Genus	Artemisia
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Artemisia annua
Linked NCBI taxonomy ID	35608
Linked level	species

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (86)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003938	Arcapillin					No. 3	No. 15
C00004603	Penduletin / 5,4'-Dihydroxy-3,6,7-trimethoxyflavone / 5-Hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one	CHEMBL165509		3 / 3 / 0		No. 3	No. 15
C00004729	Gossypetin 3,4'-dimethyl ether					No. 3	No. 15
C00004606	Mikanin / 3,5-Dihydroxy-4',6,7-trimethoxyflavone / 3,5-Dihydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL554063				No. 3	No. 15
C00004636	Tamarixetin / 4'-O-Methylquercetin / 3,3',5,7-Tetrahydroxy-4'-methoxyflavone / 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL226034		5 / 6 / 5		No. 3	No. 15
C00004646	Pachypodol / Quercetin 3,3',7-trimethyl ether / 5,4'-Dihydroxy-3,7,3'-trimethoxyflavone / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one	CHEMBL165180	C008751	1 / 2 / 0		No. 3	No. 15
C00004683	Quercetagetin 4'-methyl ether					No. 3	No. 15
C00004687	Quercetagetin 3,4'-dimethyl ether / 5,6,7,3'-Tetrahydroxy-3,4'-dimethoxyflavone / 5,6,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxy-4H-1-benzopyran-4-one					No. 3	No. 15
C00004692	Chrysosplenol D / Quercetagetin 3,6,7-Trimethyl ether / 5,3',4'-Trihydroxy-3,6,7-trimethoxyflavone / 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one	CHEMBL491366		1 / 0 / 0		No. 3	No. 15
C00004698	Eupatin	CHEMBL77588		15 / 7 / 2		No. 3	No. 15
C00004653	Retusine / Retusin(Ariocarpus) / Quercetin 3,7,3',4'-tetramethyl ether / 5-Hydroxy-3,7,3',4'-tetramethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one	CHEMBL77966		3 / 3 / 0		No. 8	No. 15
C00004705	Casticin / Vitexicarpin / Quercetagetin 3,6,7,4'-tetramethyl ether / 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one	CHEMBL452767	C054133			No. 8	No. 15
C00004712	Artemetin / 3,6,7,3',4'-Pentamethylquercetagetin / Quercetagetin 3,6,7,3',4'-pentamethyl ether / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one	CHEMBL225700	C054132		0 / 5	No. 8	No. 15
C00004709	Quercetagetin 6,7,3',4'-tetramethyl ether / 2-(3,4-Dimethoxyphenyl)-3,5-dihydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one					No. 8	No. 15
C00004704	Polycladin / Chrysosplenetin / Quercetagetin 3,6,7,3'-tetramethyl ether / 5,4'-Dihydroxy-3,6,7,3'-tetramethoxyflavone / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one	CHEMBL33256	C072749			No. 8	No. 15
C00030958	Pentacosane					No. 115
C00032307	Tetracosane / n-Tetracosane					No. 115
C00021720	beta-Cedrene / (+)-beta-Cedrene					No. 149	No. 38
C00003186	beta-Selinene		C087920			No. 151	No. 38
C00029350	Z-beta-Farnesene / (Z)-beta-Farnesene / beta-cis-Farnesene / cis-beta-Farnesene					No. 404	No. 38
C00000829	trans-Pinocarveol					No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00029913	Caryophylladienol II					No. 478	No. 38
C00029912	Caryophylladienol I					No. 478	No. 38
C00003110	Caryophyllene / (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene	CHEMBL445740 CHEMBL448700		2 / 3 / 7		No. 478	No. 38
C00029679	alpha-Bisabolol	CHEMBL519167 CHEMBL491186 CHEMBL477832 CHEMBL1096927 CHEMBL1171719 CHEMBL1561544 CHEMBL2104360	C004497	8 / 4 / 13		No. 541	No. 38
C00012425	Bicyclogermacren / Bicyclogermacrene / (+)-Bicyclogermacrene	CHEMBL509566				No. 699	No. 38
C00030470	Heneicosane					No. 732
C00032409	Tricosane					No. 732
C00030165	Eicosane		C050821			No. 732
C00030879	Octadecane		C022883			No. 732
C00034408	Amorpha-4,11-diene / (-)-Amorpha-4,11-diene					No. 834	No. 38
C00034419	Artemisinic aldehyde					No. 834	No. 38
C00044095	Artemisinic acid methyl ester					No. 834	No. 38
C00017521	Qing Hau acid / Artemisic acid / Arteannuic acid / Artemisinic acid / Artemisininic acid	CHEMBL457385	C047721		9 / 1	No. 834	No. 38
C00032374	Artemisinic alcohol / trans-Arteannuic alcohol					No. 834	No. 38
C00000155	Thymol	CHEMBL29411	D013943	9 / 17 / 14	12 / 0	No. 969	No. 35
C00000156	Carvacrol	CHEMBL281202	C073316	10 / 6 / 1	4 / 2	No. 969	No. 35
C00029674	alpha-Terpineol	CHEMBL447597 CHEMBL449810	C016775	3 / 16 / 11		No. 983	No. 35
C00011067	Tricyclene / Teresantanane					No. 1225
C00000831	(+)-trans-Sabinol		C052984			No. 1343	No. 35
C00029974	cis-Sabinol					No. 1343	No. 35
C00007636	delta-Cadinene	CHEMBL445759				No. 1524	No. 39
C00029335	beta-Ocimene / E-beta-Ocimene / (E)-beta-Ocimene		C443996			No. 1698	No. 34
C00029351	Z-beta-Ocimene / cis-beta-Ocimene / (Z)-beta-Ocimene					No. 1698	No. 34
C00000356	cis-3-Hexen-1-ol		C051918		0 / 1	No. 1746
C00000619	Eugenol	CHEMBL42710	D005054	103 / 45 / 36	152 / 28	No. 1852	No. 6
C00003051	alpha-Phellandrene	CHEMBL455041	C005403			No. 1898	No. 35
C00030481	Hexyl 3-methyl butyrate					No. 2098
C00029347	(Z)-3-Hexenyl isovalerate					No. 2098
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00029544	4-Terpineol / Terpin-4-ol / Terpineol-4 / Terpinen-4-ol	CHEMBL507795	C034019	1 / 3 / 0		No. 2215
C00003032	Chrysanthenone					No. 2232	No. 35
C00000853	Myrcene	CHEMBL455491	C008574	3 / 3 / 3		No. 2285	No. 34
C00017522	6,7-Dehydroartemisinic acid					No. 2317	No. 38
C00003061	gamma-Terpinene / 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene	CHEMBL449693	C018669			No. 2468	No. 35
C00003060	alpha-Terpinene					No. 2468	No. 35
C00011720	Germacrene D / (-)-Germacrene D	CHEMBL105432 CHEMBL1836650				No. 2639	No. 38
C00011045	delta-3-Carene / (-)-Carene(-)-3-Carene	CHEMBL506854				No. 2690	No. 35
C00029334	(E)-Anethol / trans-Anethol / trans-1-(4-Methoxyphenyl)-1-propene	CHEMBL452630 CHEMBL1468832		6 / 21 / 49		No. 2748	No. 6
C00017523	Arteannuin B / Qing Hau Sau II	CHEMBL515516 CHEMBL2002073	C006634	9 / 8 / 5	0 / 1	No. 2829
C00017524	Arteannuin C / Artemisinin C	CHEMBL515516 CHEMBL2002073		9 / 8 / 5		No. 2829
C00044150	Dihydroarteannuin B					No. 2829
C00010368	Santolina alcohol / (S)-Santolina alcohol					No. 2839
C00010827	Dehydro-1,8-cineole					No. 2943
C00029353	(Z)-Jasmone / cis-Jasmone		C086299			No. 3251
C00029972	cis-para-Mentha-2,8-dien-1-ol	CHEMBL504494 CHEMBL451087				No. 3348
C00029916	Cedr-8(15)-en-9-alpha-ol acetate					No. 3453
C00029423	1-Octen-3-ol		C038844		0 / 1	No. 3536
C00030880	Octanal / n-Octanal	CHEMBL18407	C031639		2 / 0	No. 3593
C00000358	n-Hexanol	CHEMBL14085	C036260	3 / 6 / 3		No. 3722
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00003039	Cuminaldehyde / Cuminyl aldehyde / 4-Isopropyl benzaldehyde	CHEMBL161577	C007165	2 / 4 / 2		No. 3751	No. 35
C00000821	(+)-trans-Sabinene hydrate					No. 3782	No. 35
C00012011	delta-Elemene					No. 4001
C00037033	Deoxyarteannuin B / Deoxyisoartemisinin C					No. 4141
C00037054	Dihydrodeoxyarteannuin B					No. 4141
C00007268	Farnesyl diphosphate / trans,trans-Farnesyl diphosphate	CHEMBL69330 CHEMBL1160056 CHEMBL1160060		5 / 0 / 0		No. 4178	No. 38
C00020376	beta-Guaiene		C019408			No. 4203
C00003359	quinghaosu / artemisinin / Quing hau sau	CHEMBL6978 CHEMBL77 CHEMBL9903 CHEMBL269671 CHEMBL21926 CHEMBL34365 CHEMBL76666 CHEMBL101275 CHEMBL318507 CHEMBL345083 CHEMBL142061 CHEMBL349902 CHEMBL567597 CHEMBL1358398 CHEMBL1401626 CHEMBL1523872 CHEMBL1594115 CHEMBL2111908 CHEMBL2133885	C031327	106 / 64 / 56	15 / 5	No. 4748	No. 38
C00020196	Artemisitene / Dehydroqinghaosu	CHEMBL315722 CHEMBL102244 CHEMBL155793 CHEMBL526138 CHEMBL2002513	C105118			No. 4748	No. 38
C00000136	1,8-Cineole	CHEMBL485259 CHEMBL1397305		99 / 57 / 50		No. 5413	No. 35
C00030220	Ethyl 2-methyl butyrate					No. 6377
C00029610	9-Decen-1-ol					No. 7457
C00030482	Hexyl tiglate					No. 7850
C00030130	Dihydroartemisinic acid / (-)-Dihydroartemisinic acid					No. 8620

Human Protein / Gene in interactions

170 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000155 C00000156 C00000619 C00029544 C00029674	3 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000136 C00000155 C00003359 C00029334 C00029674	11 / 10
P16473	Thyrotropin receptor	Glycohormone receptor	C00000136 C00000358 C00000805 C00000853 C00029334	3 / 2
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000136 C00000619 C00003359 C00029334 C00029679	0 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00000136 C00000619 C00000805 C00003359 C00029679	0 / 0
O75496	Geminin	Unclassified protein	C00000136 C00000619 C00003359 C00017523 C00017524	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000136 C00000155 C00000619 C00003359 C00029679	0 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000136 C00000156 C00000619 C00003359	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000136 C00000619 C00003359 C00004636	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000136 C00003359 C00017523 C00017524	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000136 C00000619 C00000853 C00003359	0 / 1
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000155 C00000156 C00000619 C00029674	5 / 1
P08311	Cathepsin G	S1A	C00000136 C00000619 C00003359	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000136 C00000619 C00003359	2 / 2
P08246	Neutrophil elastase	S1A	C00000136 C00000619 C00003359	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00000136 C00000619 C00003359	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000136 C00000619 C00003359	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000136 C00000619 C00003359	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000136 C00000619 C00003359	0 / 0
P29466	Caspase-1	C14	C00000136 C00000619 C00003359	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000136 C00000619 C00003359	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000136 C00000619 C00003359	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000136 C00000619 C00003359	2 / 2
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00003359	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000136 C00000619 C00003359	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00003359	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000136 C00000619 C00003359	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00003359	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000136 C00000619 C00003359	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00003359 C00017523 C00017524	1 / 1
P35367	Histamine H1 receptor	Histamine receptor	C00000136 C00000619 C00003359	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000136 C00000619 C00003359	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000136 C00000619 C00003359	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00003359	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00003359	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000136 C00000619 C00003359	1 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004603 C00004646 C00004653	2 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00003359	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000136 C00000619 C00003359	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000136 C00000619 C00003359	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000136 C00000619 C00003359	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000136 C00000619 C00003359	0 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000358 C00017523 C00017524	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000136 C00000619 C00003359	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00003359	2 / 0
P03372	Estrogen receptor	NR3A1	C00000136 C00000619 C00003359	1 / 1
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000136 C00000619 C00003359	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000136 C00000619 C00003359	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000136 C00000619 C00003359	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000136 C00000619 C00003359	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000136 C00000619 C00003359	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000136 C00000619 C00003359	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000136 C00000619 C00003359	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000136 C00000619 C00003359	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000619 C00003359 C00029334	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000136 C00000619 C00003359	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000155 C00000156 C00000619	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000136 C00000619 C00003359	0 / 1
P22303	Acetylcholinesterase	Hydrolase	C00000136 C00000619 C00003359	1 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000136 C00000619 C00003359	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000155 C00000156 C00000619	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000155 C00000156 C00000619	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000136 C00000619 C00003359	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00003359	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00003359	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000136 C00000619 C00003359	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00003359	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000136 C00000619 C00003359	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000136 C00000619 C00003359	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000136 C00000619 C00003359	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000136 C00000619 C00003359	1 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000136 C00000619 C00003359	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000136 C00000619 C00003359	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000136 C00000619 C00003359	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000136 C00000619 C00003359	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000136 C00000619 C00003359	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00003359	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000136 C00000619 C00003359	1 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000136 C00000619 C00003359	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000136 C00000619 C00003359	1 / 1
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000136 C00000619 C00003359	2 / 1
P03956	Interstitial collagenase	M10A	C00000136 C00000619 C00003359	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000136 C00000619 C00003359	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000136 C00000619 C00003359	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00003359 C00017523 C00017524	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000136 C00000619 C00003359	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000136 C00000619 C00003359	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00000155 C00000156 C00000619	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000136 C00000619 C00003359	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000136 C00000619 C00003359	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000136 C00000619 C00003359	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000136 C00000619 C00003359	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000136 C00000619 C00003359	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000136 C00000619 C00003359	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000136 C00000619 C00003359	1 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000136 C00000619 C00003359	0 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000136 C00000619 C00003359	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000136 C00000619 C00003359	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000136 C00000619 C00003359	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000136 C00000619 C00003359	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000136 C00000619 C00003359	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000136 C00000619 C00003359	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000136 C00000619 C00003359	1 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000136 C00000619 C00003359	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00017523 C00017524	0 / 0
P15121	Aldose reductase	Enzyme	C00004603 C00004692	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00017523 C00017524	2 / 0
P08183	Multidrug resistance protein 1	drug	C00004603 C00004653	1 / 0
P10275	Androgen receptor	NR3C4	C00000136 C00000619	3 / 4
O75762	Transient receptor potential cation channel subfamily A member 1	Unclassified protein	C00000155 C00000156	1 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000156 C00000619	0 / 0
O75030	Microphthalmia-associated transcription factor	Unclassified protein	C00017523 C00017524	4 / 4
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00017523 C00017524	1 / 0
O00255	Menin	Unclassified protein	C00003110 C00029679	2 / 5
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000156 C00000619	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003110 C00029679	1 / 2
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00029679	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00003359	2 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00003359	3 / 3
P55055	Oxysterols receptor LXR-beta	NR1H3	C00000136	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00000136	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00000853	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00004636	4 / 4
P14679	Tyrosinase	Oxidoreductase	C00003039	4 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00029679	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00000619	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00003359	7 / 3
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805	0 / 0
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00029679	1 / 2
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00003039	0 / 0
P10145	Interleukin-8	Secreted protein	C00000619	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00003359	0 / 0
P42858	Huntingtin	Unclassified protein	C00003359	1 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00000136	4 / 3
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003359	0 / 0
P04792	Heat shock protein beta-1	Unclassified protein	C00004636	2 / 1
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00004636	0 / 0
O95749	Geranylgeranyl pyrophosphate synthase	Enzyme	C00007268	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000358	3 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00003359	1 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00004636	0 / 0
Q7Z2W7	Transient receptor potential cation channel subfamily M member 8	Unclassified protein	C00000136	0 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00000619	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00029334	7 / 37
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00029334	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000136	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00004653	0 / 0
O75469	Nuclear receptor subfamily 1 group I member 2	NR1I2	C00003359	0 / 0
P37268	Squalene synthase	Enzyme	C00007268	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00003359	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00003359	1 / 4
P49356	Protein farnesyltransferase subunit beta	Enzyme	C00007268	0 / 0
P49354	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	Enzyme	C00007268	0 / 0
P53609	Geranylgeranyl transferase type-1 subunit beta	Enzyme	C00007268	0 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	C00004698	0 / 0
P68366	Tubulin alpha-4A chain	Structural	C00004698	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	C00004698	1 / 0
P04350	Tubulin beta-4A chain	Structural	C00004698	2 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	C00004698	0 / 0
P07437	Tubulin beta chain	Structural	C00004698	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	C00004698	1 / 1
P68371	Tubulin beta-4B chain	Structural	C00004698	0 / 0
Q13509	Tubulin beta-3 chain	Structural	C00004698	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00003359	1 / 1
P68363	Tubulin alpha-1B chain	Unclassified protein	C00004698	0 / 0
Q13885	Tubulin beta-2A chain	Structural	C00004698	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	C00004698	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	C00004698	0 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	C00004698	0 / 0
Q9BVA1	Tubulin beta-2B chain	Structural	C00004698	1 / 0

179 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
162514	TRPV3, OLMS, VRL3	transient receptor potential cation channel, subfamily V, member 3	C00000155 C00000156 C00000619
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000156 C00000619
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000155 C00000619
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000155 C00000619
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000155 C00000619
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000155 C00000619
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000155 C00000619
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000155 C00000619
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00000619 C00003359
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000619 C00003359
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000619 C00003359
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00000619 C00003359
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000155 C00000156
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000619 C00030880
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00000619 C00003359
5327	PLAT, T-PA, TPA	plasminogen activator, tissue (EC:3.4.21.68)	C00000619
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00003359
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00030880
1050	CEBPA, C/EBP-alpha, CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	C00017521
1638	DCT, TRP-2, TYRP2	dopachrome tautomerase (EC:5.3.3.12)	C00017521
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00017521
3815	KIT, C-Kit, CD117, PBT, SCFR	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (EC:2.7.10.1)	C00017521
4254	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7	KIT ligand	C00017521
4282	MIF, GIF, GLIF, MMIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1)	C00017521
4286	MITF, CMM8, MI, WS2, WS2A, bHLHe32	microphthalmia-associated transcription factor	C00017521
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00017521
7306	TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN	tyrosinase-related protein 1 (EC:1.14.18.-)	C00017521
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00003359
8989	TRPA1, ANKTM1, FEPS	transient receptor potential cation channel, subfamily A, member 1	C00000156
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00003359
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00003359
23460	ABCA6, EST155051	ATP-binding cassette, sub-family A (ABC1), member 6	C00000619
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000619
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00000619
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000619
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000619
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00000619
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00000619
55114	ARHGAP17, MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH1, RICH1B, WBP15	Rho GTPase activating protein 17	C00000619
10123	ARL4C, ARL7, LAK	ADP-ribosylation factor-like 4C	C00000619
567	B2M	beta-2-microglobulin	C00000619
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00003359
9774	BCLAF1, BTF, bK211L9.1	BCL2-associated transcription factor 1	C00000619
654	BMP6, VGR, VGR1	bone morphogenetic protein 6	C00000619
699	BUB1, BUB1A, BUB1L, hBUB1	BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1)	C00000619
57102	C12orf4	chromosome 12 open reading frame 4	C00000619
10203	CALCRL, CGRPR, CRLR	calcitonin receptor-like	C00000619
847	CAT	catalase (EC:1.11.1.6)	C00000619
6357	CCL13, CKb10, MCP-4, NCC-1, NCC1, SCYA13, SCYL1	chemokine (C-C motif) ligand 13	C00000619
6363	CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19	chemokine (C-C motif) ligand 19	C00000619
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00000619
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00000619
6349	CCL3L1, 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MIP1AP, SCYA3L, SCYA3L1	chemokine (C-C motif) ligand 3-like 1	C00000619
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00000619
729230	CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R	chemokine (C-C motif) receptor 2	C00000619
1234	CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22	chemokine (C-C motif) receptor 5 (gene/pseudogene)	C00000619
1236	CCR7, BLR2, CD197, CDw197, CMKBR7, EBI1	chemokine (C-C motif) receptor 7	C00000619
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00000619
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00000619
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00000619
1390	CREM, CREM-2, ICER, hCREM-2	cAMP responsive element modulator	C00000619
1514	CTSL, CATL, CTSL1, MEP	cathepsin L (EC:3.4.22.15)	C00000619
2919	CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	C00000619
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00000619
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000619
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000619
1593	CYP27A1, CP27, CTX, CYP27	cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15)	C00000619
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000619
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00000619
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00000619
1736	DKC1, CBF5, DKC, DKCX, NAP57, NOLA4, XAP101	dyskeratosis congenita 1, dyskerin	C00000619
9787	DLGAP5, DLG7, HURP	discs, large (Drosophila) homolog-associated protein 5	C00000619
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00000619
1870	E2F2, E2F-2	E2F transcription factor 2	C00000619
1871	E2F3, E2F-3	E2F transcription factor 3	C00000619
1874	E2F4, E2F-4	E2F transcription factor 4, p107/p130-binding	C00000619
1875	E2F5, E2F-5	E2F transcription factor 5, p130-binding	C00000619
1876	E2F6, E2F-6	E2F transcription factor 6	C00000619
1959	EGR2, AT591, CMT1D, CMT4E, KROX20	early growth response 2	C00000619
133418	EMB	embigin	C00000619
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000619
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000619
2162	F13A1, F13A	coagulation factor XIII, A1 polypeptide (EC:2.3.2.13)	C00000619
26268	FBXO9, FBX9, NY-REN-57, VCIA1, dJ341E18.2	F-box protein 9	C00000619
2213	FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2	Fc fragment of IgG, low affinity IIb, receptor (CD32)	C00000619
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00000619
2355	FOSL2, FRA2	FOS-like antigen 2	C00000619
2512	FTL, NBIA3	ferritin, light polypeptide	C00000619
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00000619
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00000619
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00000619
644076	GLYCAM1	glycosylation dependent cell adhesion molecule 1 (pseudogene)	C00000619
2878	GPX3, GPx-P, GSHPx-3, GSHPx-P	glutathione peroxidase 3 (plasma) (EC:1.11.1.9)	C00000619
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00000619
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00000619
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00000619
2994	GYPB, CD235b, GPB, GPB.NY, GYPHe.NY, GpMiIII, HGpMiIII, HGpMiVI, HGpMiX, MNS, PAS-3, SS	glycophorin B (MNS blood group)	C00000619
54497	HEATR5B	HEAT repeat containing 5B	C00000619
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00000619
3106	HLA-B, AS, HLAB, SPDA1	major histocompatibility complex, class I, B	C00000619
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000619
220988	HNRNPA3, 2610510D13Rik, D10S102, FBRNP, HNRPA3	heterogeneous nuclear ribonucleoprotein A3	C00000619
3381	IBSP, BNSP, BSP, BSP-II, SP-II	integrin-binding sialoprotein	C00000619
3422	IDI1, IPP1, IPPI1	isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2)	C00000619
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000619
7850	IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB	interleukin 1 receptor, type II	C00000619
3575	IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA	interleukin 7 receptor	C00000619
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000619
26034	IPCEF1, PIP3-E, RP3-402L9.2	interaction protein for cytohesin exchange factors 1	C00000619
3655	ITGA6, CD49f, ITGA6B, VLA-6	integrin, alpha 6	C00000619
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00000619
3741	KCNA5, ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1	potassium voltage-gated channel, shaker-related subfamily, member 5	C00000619
3759	KCNJ2, ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3	potassium inwardly-rectifying channel, subfamily J, member 2	C00000619
9493	KIF23, CHO1, KNSL5, MKLP-1, MKLP1	kinesin family member 23	C00000619
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00000619
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00000619
7975	MAFK, NFE2U, P18	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	C00000619
28985	MCTS1, MCT-1, MCT1	malignant T cell amplified sequence 1	C00000619
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00000619
4257	MGST1, GST12, MGST, MGST-I	microsomal glutathione S-transferase 1 (EC:2.5.1.18)	C00000619
51318	MRPL35, L35mt, MRP-L35	mitochondrial ribosomal protein L35	C00000619
58475	MS4A7, 4SPAN2, CD20L4, CFFM4, MS4A8	membrane-spanning 4-domains, subfamily A, member 7	C00000619
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00000619
4084	MXD1, BHLHC58, MAD, MAD1	MAX dimerization protein 1	C00000619
4602	MYB, Cmyb, c-myb, c-myb_CDS, efg	v-myb avian myeloblastosis viral oncogene homolog	C00000619
10135	NAMPT, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN	nicotinamide phosphoribosyltransferase (EC:2.4.2.12)	C00000619
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000619
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000619
4927	NUP88	nucleoporin 88kDa	C00000619
10606	PAICS, ADE2, ADE2H1, AIRC, PAIS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (EC:6.3.2.6 4.1.1.21)	C00000619
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00000619
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00000619
8301	PICALM, CALM, CLTH, LAP	phosphatidylinositol binding clathrin assembly protein	C00000619
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00003359
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00000619
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00000619
10935	PRDX3, AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III	peroxiredoxin 3 (EC:1.11.1.15)	C00000619
5733	PTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, PGE2-R	prostaglandin E receptor 3 (subtype EP3)	C00000619
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00000619
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000619
5996	RGS1, 1R20, BL34, IER1, IR20	regulator of G-protein signaling 1	C00000619
6157	RPL27A, L27A	ribosomal protein L27a	C00000619
50484	RRM2B, MTDPS8A, MTDPS8B, P53R2	ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1)	C00000619
6303	SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1	spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57)	C00000619
6383	SDC2, CD362, HSPG, HSPG1, SYND2	syndecan 2	C00000619
55752	SEPT11	septin 11	C00000619
6504	SLAMF1, CD150, CDw150, SLAM	signaling lymphocytic activation molecule family member 1	C00000619
117247	SLC16A10, MCT10, PRO0813, TAT1	solute carrier family 16 (aromatic amino acid transporter), member 10	C00000619
6515	SLC2A3, GLUT3	solute carrier family 2 (facilitated glucose transporter), member 3	C00000619
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00000619
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00000619
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00000619
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00000619
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00000619
6775	STAT4, SLEB11	signal transducer and activator of transcription 4	C00000619
6777	STAT5B, STAT5	signal transducer and activator of transcription 5B	C00000619
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00000619
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000619
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00000619
7130	TNFAIP6, TSG-6, TSG6	tumor necrosis factor, alpha-induced protein 6	C00000619
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000619
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00000619
25828	TXN2, MT-TRX, MTRX, TRX2	thioredoxin 2	C00000619
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000619
10587	TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2	thioredoxin reductase 2 (EC:1.8.1.9)	C00000619
7358	UGDH, GDH, UDP-GlcDH, UDPGDH, UGD	UDP-glucose 6-dehydrogenase (EC:1.1.1.22)	C00000619
1555	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450	cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1)	C00003359
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00000619
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00003359
8714	ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	C00003359
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00003359
7367	UGT2B17, BMND12, UDPGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17)	C00000619
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00000619
7709	ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67	zinc finger and BTB domain containing 17	C00000619
9131	AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	C00000155
581	BAX, BCL2L4	BCL2-associated X protein	C00000155
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000155
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000155

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