PCIDB

KNApSAcK Metabolite C00000619

Metabolite

KNApSAcK Entry

id C00000619
Name Eugenol
CAS RN 97-53-0
Standard InChI InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3
Standard InChI (Main Layer) InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3

Cluster

Phytochemical cluster No. 6
KCF-S cluster No. 1852

Link

ChEMBL

By standard InChI CHEMBL42710
By standard InChI Main Layer CHEMBL42710

KEGG

By LinkDB C10453

CTD

By CAS RN D005054

Species

Summary

Plant class

class name count
asterids 9
Magnoliophyta 7
rosids 6
Embryophyta 1

Family (Top 10)

family name count
Lauraceae 4
Asteraceae 3
Lamiaceae 3
Myrtaceae 2
Brassicaceae 2
Solanaceae 2
Piperaceae 2
Aneuraceae 1
Rosaceae 1
Myristicaceae 1

List (24)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Achillea fragrantissima 282738 Asteraceae asterids Viridiplantae
Artemisia annua 35608 Asteraceae asterids Viridiplantae
Artemisia klotzschiana 1227627 Asteraceae asterids Viridiplantae
Brassica hirta 3728 Brassicaceae rosids Viridiplantae
Cinnamomum illicioides 13428 Lauraceae Magnoliophyta Viridiplantae
Cinnamomum spp. 13428 Lauraceae Magnoliophyta Viridiplantae
Cinnamomum subavenium MIQ. 977953 Lauraceae Magnoliophyta Viridiplantae
Cistus creticus 191224 Cistaceae rosids Viridiplantae
Eugenia caryophyllata 219868 Myrtaceae rosids Viridiplantae
Hesperis matronalis 264418 Brassicaceae rosids Viridiplantae
Jackiella javanica
Lippia javanica 925357 Verbenaceae asterids Viridiplantae
Mandragora autumnalis 389206 Solanaceae asterids Viridiplantae
Myristica fragrans 51089 Myristicaceae Magnoliophyta Viridiplantae
Nicotiana bonariensis 118694 Solanaceae asterids Viridiplantae
Ocimum spp. 39173 Lamiaceae asterids Viridiplantae
Origanum majorana 268884 Lamiaceae asterids Viridiplantae
Peperomia sui 13196 Piperaceae Magnoliophyta Viridiplantae
Pimenta dioica 375272 Myrtaceae rosids Viridiplantae
Piper betle 13217 Piperaceae Magnoliophyta Viridiplantae
Plectranthus marrubioides 41227 Lamiaceae asterids Viridiplantae
Riccardia multifida subsp. Decrescens 39025 Aneuraceae Embryophyta Viridiplantae
Rosa rugosa 74645 Rosaceae rosids Viridiplantae
Sassafras randaiense 434240 Lauraceae Magnoliophyta Viridiplantae

Human Protein / Gene in interaction

103 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL42710 CHEMBL1909136 (2)
1 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme CHEMBL42710 CHEMBL816283 (1) CHEMBL1908081 (1)
CHEMBL1908082 (1)
3 / 0
O75795 UDP-glucuronosyltransferase 2B17 Enzyme CHEMBL42710 CHEMBL1743337 (1) CHEMBL1908091 (2)
1 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme CHEMBL42710 CHEMBL1908087 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL42710 CHEMBL1909139 (2)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL42710 CHEMBL1014032 (1) CHEMBL1014033 (1)
CHEMBL1014036 (1) CHEMBL1008495 (1)
CHEMBL1008498 (1) CHEMBL1909131 (2)
0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL42710 CHEMBL1909190 (2)
2 / 2
P08246 Neutrophil elastase S1A CHEMBL42710 CHEMBL1909195 (2)
2 / 1
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL42710 CHEMBL1909215 (2)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL42710 CHEMBL1909201 (2)
0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor CHEMBL42710 CHEMBL1909176 (2)
0 / 0
P29466 Caspase-1 C14 CHEMBL42710 CHEMBL1909193 (2)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL42710 CHEMBL1909198 (2)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL42710 CHEMBL1909199 (2)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL42710 CHEMBL1909197 (2)
2 / 2
P00918 Carbonic anhydrase 2 Lyase CHEMBL42710 CHEMBL1909123 (2)
1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL42710 CHEMBL1909092 (2)
0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL42710 CHEMBL1909169 (2)
1 / 1
P25021 Histamine H2 receptor Histamine receptor CHEMBL42710 CHEMBL1909157 (2)
0 / 0
P35367 Histamine H1 receptor Histamine receptor CHEMBL42710 CHEMBL1909156 (2)
0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine CHEMBL42710 CHEMBL1909143 (2)
1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor CHEMBL42710 CHEMBL1909174 (2)
0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL42710 CHEMBL1909090 (2)
0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor CHEMBL42710 CHEMBL1909093 (2)
0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor CHEMBL42710 CHEMBL1909127 (2)
0 / 0
P06241 Tyrosine-protein kinase Fyn Src CHEMBL42710 CHEMBL1909204 (2)
0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr CHEMBL42710 CHEMBL1909202 (2)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL42710 CHEMBL1909135 (2)
0 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL42710 CHEMBL1909203 (2)
1 / 11
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL42710 CHEMBL1909140 (2)
2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL42710 CHEMBL1008496 (1) CHEMBL1008497 (1)
CHEMBL1909130 (2)
0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor CHEMBL42710 CHEMBL1909120 (2)
0 / 0
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL42710 CHEMBL1909181 (2)
0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor CHEMBL42710 CHEMBL1909164 (2)
0 / 0
P29274 Adenosine receptor A2a Adenosine receptor CHEMBL42710 CHEMBL1909214 (2)
0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor CHEMBL42710 CHEMBL1909175 (2)
0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor CHEMBL42710 CHEMBL1909096 (2)
1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr CHEMBL42710 CHEMBL1909118 (2)
0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor CHEMBL42710 CHEMBL1909166 (2)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL42710 CHEMBL1614458 (1)
0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL42710 CHEMBL1909133 (2)
0 / 0
O75496 Geminin Unclassified protein CHEMBL42710 CHEMBL2114780 (1)
0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme CHEMBL42710 CHEMBL1908086 (1)
0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme CHEMBL42710 CHEMBL1908090 (1)
0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase CHEMBL42710 CHEMBL1909158 (2)
0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor CHEMBL42710 CHEMBL1909088 (2)
0 / 0
P21917 D(4) dopamine receptor Dopamine receptor CHEMBL42710 CHEMBL1909142 (2)
0 / 0
P30988 Calcitonin receptor Calcitonin receptor CHEMBL42710 CHEMBL1909101 (2)
0 / 0
P35462 D(3) dopamine receptor Dopamine receptor CHEMBL42710 CHEMBL1909141 (2)
1 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL42710 CHEMBL1909180 (2)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL42710 CHEMBL1909146 (2)
0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor CHEMBL42710 CHEMBL1909104 (2)
0 / 0
P25101 Endothelin-1 receptor Endothelin receptor CHEMBL42710 CHEMBL1909144 (2)
0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor CHEMBL42710 CHEMBL1909100 (2)
0 / 0
P10145 Interleukin-8 Secreted protein CHEMBL42710 CHEMBL2114835 (1)
0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor CHEMBL42710 CHEMBL1909167 (2)
1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor CHEMBL42710 CHEMBL1909129 (2)
0 / 0
P08311 Cathepsin G S1A CHEMBL42710 CHEMBL1909194 (2)
0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor CHEMBL42710 CHEMBL1909110 (2)
1 / 0
P03956 Interstitial collagenase M10A CHEMBL42710 CHEMBL1909196 (2)
0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor CHEMBL42710 CHEMBL1909119 (2)
0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL42710 CHEMBL1794342 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL42710 CHEMBL1909150 (2)
0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor CHEMBL42710 CHEMBL1909171 (2)
2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor CHEMBL42710 CHEMBL1909170 (2)
0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor CHEMBL42710 CHEMBL1909122 (2)
0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin CHEMBL42710 CHEMBL1909109 (2)
2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL42710 CHEMBL1909205 (2)
5 / 10
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor CHEMBL42710 CHEMBL1909172 (2)
1 / 0
P21452 Substance-K receptor Neurokinin receptor CHEMBL42710 CHEMBL1909114 (2)
0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor CHEMBL42710 CHEMBL1909125 (2)
0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor CHEMBL42710 CHEMBL1909126 (2)
3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor CHEMBL42710 CHEMBL1909108 (2)
0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor CHEMBL42710 CHEMBL1909124 (2)
1 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL42710 CHEMBL1909200 (2)
0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme CHEMBL42710 CHEMBL1909207 (2)
2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL42710 CHEMBL1909132 (2)
0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme CHEMBL42710 CHEMBL1908085 (2)
0 / 0
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme CHEMBL42710 CHEMBL1908088 (1)
0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A CHEMBL42710 CHEMBL1909186 (2)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL42710 CHEMBL1909145 (2)
1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor CHEMBL42710 CHEMBL1909091 (2)
1 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL42710 CHEMBL1909212 (2)
1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL42710 CHEMBL1909211 (2)
0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor CHEMBL42710 CHEMBL1909105 (2)
0 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL42710 CHEMBL1909182 (2)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL42710 CHEMBL1909173 (2)
0 / 0
P25103 Substance-P receptor Neurokinin receptor CHEMBL42710 CHEMBL1909113 (2)
0 / 0
P25105 Platelet-activating factor receptor PAF receptor CHEMBL42710 CHEMBL1909187 (2)
0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor CHEMBL42710 CHEMBL1909168 (2)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL42710 CHEMBL1909134 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL42710 CHEMBL1614108 (1) CHEMBL1613886 (1)
CHEMBL1909138 (2)
0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 CHEMBL42710 CHEMBL1909137 (2)
0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme CHEMBL42710 CHEMBL1908080 (2)
5 / 1
P19224 UDP-glucuronosyltransferase 1-6 Enzyme CHEMBL42710 CHEMBL1908083 (1)
0 / 0
P10275 Androgen receptor NR3C4 CHEMBL42710 CHEMBL1112517 (1) CHEMBL1113403 (3)
CHEMBL1113404 (1) CHEMBL1794560 (1)
3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine CHEMBL42710 CHEMBL1909094 (2)
1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor CHEMBL42710 CHEMBL1909087 (2)
0 / 0
P30542 Adenosine receptor A1 Adenosine receptor CHEMBL42710 CHEMBL1909213 (2)
0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor CHEMBL42710 CHEMBL1909089 (2)
0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 CHEMBL42710 CHEMBL1909116 (2)
1 / 1
P06239 Tyrosine-protein kinase Lck Src CHEMBL42710 CHEMBL1909206 (2)
0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor CHEMBL42710 CHEMBL1909128 (2)
0 / 0

CTD interaction (205)

compound gene gene name gene description interaction interaction type form reference
pmid
D005054 23460 ABCA6
EST155051
ATP-binding cassette, sub-family A (ABC1), member 6 Eugenol results in decreased expression of ABCA6 mRNA decreases expression
mRNA 17374397
D005054 196 AHR
bHLHe76
aryl hydrocarbon receptor Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] decreases reaction
/ increases activity
protein 17275817
D005054 231 AKR1B1
ADR
ALDR1
ALR2
AR
aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) Eugenol results in increased expression of AKR1B1 mRNA increases expression
mRNA 20566472
D005054 57016 AKR1B10
AKR1B11
AKR1B12
ALDRLn
ARL-1
ARL1
HIS
HSI
aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) Eugenol results in increased expression of AKR1B10 mRNA increases expression
mRNA 20566472
D005054 1645 AKR1C1
2-ALPHA-HSD
20-ALPHA-HSD
C9
DD1
DD1/DD2
DDH
DDH1
H-37
HAKRC
HBAB
MBAB
aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) Eugenol results in increased expression of AKR1C1 mRNA increases expression
mRNA 20566472
D005054 8644 AKR1C3
DD3
DDX
HA1753
HAKRB
HAKRe
HSD17B5
PGFS
hluPGFS
aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) Eugenol results in increased expression of AKR1C3 mRNA increases expression
mRNA 20566472
D005054 249 ALPL
AP-TNAP
APTNAP
HOPS
TNAP
TNSALP
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) Eugenol results in increased expression of ALPL mRNA increases expression
mRNA 22083529
D005054 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Eugenol binds to and results in decreased activity of AR protein affects binding
/ decreases activity
protein 20226658
D005054 55114 ARHGAP17
MST066
MST110
MSTP038
MSTP066
MSTP110
NADRIN
PP367
PP4534
RICH1
RICH1B
WBP15
Rho GTPase activating protein 17 Eugenol results in decreased expression of ARHGAP17 mRNA decreases expression
mRNA 17374397
D005054 10123 ARL4C
ARL7
LAK
ADP-ribosylation factor-like 4C Eugenol results in increased expression of ARL4C mRNA increases expression
mRNA 17374397
D005054 567 B2M
beta-2-microglobulin Eugenol results in increased expression of B2M mRNA increases expression
mRNA 17936526
D005054 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Eugenol results in decreased expression of BCL2 mRNA decreases expression
mRNA 21939359
D005054 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Eugenol results in increased activity of sulforafan] which results in decreased expression of BCL2 decreases expression
/ increases activity
21382956
D005054 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [sulforafan results in increased activity of Eugenol] which results in decreased expression of BCL2 decreases expression
/ increases activity
21382956
D005054 9774 BCLAF1
BTF
bK211L9.1
BCL2-associated transcription factor 1 Eugenol results in decreased expression of BCLAF1 mRNA decreases expression
mRNA 17374397
D005054 654 BMP6
VGR
VGR1
bone morphogenetic protein 6 Eugenol results in increased expression of BMP6 mRNA increases expression
mRNA 17374397
D005054 699 BUB1
BUB1A
BUB1L
hBUB1
BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) Eugenol results in decreased expression of BUB1 mRNA decreases expression
mRNA 17374397
D005054 57102 C12orf4
chromosome 12 open reading frame 4 Eugenol results in decreased expression of C12ORF4 mRNA decreases expression
mRNA 17374397
D005054 10203 CALCRL
CGRPR
CRLR
calcitonin receptor-like Eugenol results in increased expression of CALCRL mRNA increases expression
mRNA 17374397
D005054 847 CAT
catalase (EC:1.11.1.6) CAT protein inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol] affects cotreatment
/ decreases reaction
/ increases activity
protein 15576237
D005054 847 CAT
catalase (EC:1.11.1.6) Eugenol results in increased expression of CAT mRNA increases expression
mRNA 20566472
D005054 6357 CCL13
CKb10
MCP-4
NCC-1
NCC1
SCYA13
SCYL1
chemokine (C-C motif) ligand 13 Eugenol results in increased expression of CCL13 mRNA increases expression
mRNA 17936526
D005054 6363 CCL19
CKb11
ELC
MIP-3b
MIP3B
SCYA19
chemokine (C-C motif) ligand 19 Eugenol results in increased expression of CCL19 mRNA increases expression
mRNA 17936526
D005054 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Eugenol results in decreased expression of CCL2 mRNA decreases expression
mRNA 17374397
17936526
D005054 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Eugenol results in increased expression of CCL2 mRNA increases expression
mRNA 15585374
D005054 6348 CCL3
G0S19-1
LD78ALPHA
MIP-1-alpha
MIP1A
SCYA3
chemokine (C-C motif) ligand 3 Eugenol results in increased expression of CCL3 mRNA increases expression
mRNA 15585374
D005054 6349 CCL3L1
464.2
D17S1718
G0S19-2
LD78
LD78BETA
MIP1AP
SCYA3L
SCYA3L1
chemokine (C-C motif) ligand 3-like 1 Eugenol results in increased expression of CCL3L1 mRNA increases expression
mRNA 20713136
D005054 6351 CCL4
ACT2
AT744.1
G-26
HC21
LAG-1
LAG1
MIP-1-beta
MIP1B
MIP1B1
SCYA2
SCYA4
chemokine (C-C motif) ligand 4 Eugenol results in increased expression of CCL4 mRNA increases expression
mRNA 15585374
D005054 6351 CCL4
ACT2
AT744.1
G-26
HC21
LAG-1
LAG1
MIP-1-beta
MIP1B
MIP1B1
SCYA2
SCYA4
chemokine (C-C motif) ligand 4 Eugenol results in increased expression of CCL4 protein increases expression
protein 18353026
D005054 729230 CCR2
CC-CKR-2
CCR-2
CCR2A
CCR2B
CD192
CKR2
CKR2A
CKR2B
CMKBR2
MCP-1-R
chemokine (C-C motif) receptor 2 Eugenol results in decreased expression of CCR2 mRNA decreases expression
mRNA 17374397
D005054 1234 CCR5
CC-CKR-5
CCCKR5
CCR-5
CD195
CKR-5
CKR5
CMKBR5
IDDM22
chemokine (C-C motif) receptor 5 (gene/pseudogene) Eugenol results in increased expression of CCR5 mRNA increases expression
mRNA 17936526
20713136
D005054 1236 CCR7
BLR2
CD197
CDw197
CMKBR7
EBI1
chemokine (C-C motif) receptor 7 Eugenol results in increased expression of CCR7 mRNA increases expression
mRNA 17374397
D005054 948 CD36
BDPLT10
CHDS7
FAT
GP3B
GP4
GPIV
PASIV
SCARB3
CD36 molecule (thrombospondin receptor) Eugenol results in decreased expression of CD36 mRNA decreases expression
mRNA 17374397
D005054 942 CD86
B7-2
B7.2
B70
CD28LG2
LAB72
CD86 molecule [Dicumarol results in decreased activity of NQO1 protein] inhibits the reaction [Eugenol results in increased expression of CD86 protein] decreases activity
/ decreases reaction
/ increases expression
protein 21742781
D005054 942 CD86
B7-2
B7.2
B70
CD28LG2
LAB72
CD86 molecule Eugenol results in increased expression of CD86 protein increases expression
protein 12423654
20488241
21742781
D005054 1385 CREB1
CREB
cAMP responsive element binding protein 1 Eugenol affects the expression of CREB1 mRNA affects expression
mRNA 20385217
D005054 1390 CREM
CREM-2
ICER
hCREM-2
cAMP responsive element modulator Eugenol results in increased expression of CREM mRNA increases expression
mRNA 17374397
D005054 1514 CTSL
CATL
CTSL1
MEP
cathepsin L (EC:3.4.22.15) Eugenol results in increased expression of CTSL mRNA increases expression
mRNA 17374397
D005054 2919 CXCL1
FSP
GRO1
GROa
MGSA
MGSA-a
NAP-3
SCYB1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Eugenol results in increased expression of CXCL1 mRNA increases expression
mRNA 20713136
D005054 7852 CXCR4
CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
chemokine (C-X-C motif) receptor 4 Eugenol results in increased expression of CXCR4 mRNA increases expression
mRNA 20713136
D005054 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) [CYP1A1 protein co-treated with Copper] results in increased activity of Eugenol affects cotreatment
/ increases activity
protein 15576237
D005054 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 17275817
D005054 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Eugenol inhibits the reaction [CYP1A1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene] decreases reaction
/ increases activity
/ increases metabolic processing
protein 17275817
D005054 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Eugenol results in decreased activity of CYP1A1 protein decreases activity
protein 17275817
D005054 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Eugenol results in decreased expression of CYP1A1 mRNA decreases expression
mRNA 20713136
D005054 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) [CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol affects cotreatment
/ increases activity
protein 15576237
D005054 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] decreases reaction
/ increases expression
mRNA 17275817
D005054 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Eugenol inhibits the reaction [CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene] decreases reaction
/ increases activity
/ increases metabolic processing
protein 17275817
D005054 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Eugenol results in decreased activity of CYP1B1 protein decreases activity
protein 17275817
D005054 1593 CYP27A1
CP27
CTX
CYP27
cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15) Eugenol results in decreased expression of CYP27A1 mRNA decreases expression
mRNA 20713136
D005054 1559 CYP2C9
CPC9
CYP2C
CYP2C10
CYPIIC9
P450IIC9
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) [CYP2C9 protein co-treated with Copper] results in increased activity of Eugenol affects cotreatment
/ increases activity
protein 15576237
D005054 1565 CYP2D6
CPD6
CYP2D
CYP2D7AP
CYP2D7BP
CYP2D7P2
CYP2D8P2
CYP2DL1
CYPIID6
P450-DB1
P450C2D
P450DB1
cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) bathocuproine inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol] affects cotreatment
/ decreases reaction
/ increases activity
protein 15576237
D005054 1565 CYP2D6
CPD6
CYP2D
CYP2D7AP
CYP2D7BP
CYP2D7P2
CYP2D8P2
CYP2DL1
CYPIID6
P450-DB1
P450C2D
P450DB1
cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) CAT protein inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol] affects cotreatment
/ decreases reaction
/ increases activity
protein 15576237
D005054 1565 CYP2D6
CPD6
CYP2D
CYP2D7AP
CYP2D7BP
CYP2D7P2
CYP2D8P2
CYP2DL1
CYPIID6
P450-DB1
P450C2D
P450DB1
cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) [CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol affects cotreatment
/ increases activity
protein 15576237
D005054 1565 CYP2D6
CPD6
CYP2D
CYP2D7AP
CYP2D7BP
CYP2D7P2
CYP2D8P2
CYP2DL1
CYPIID6
P450-DB1
P450C2D
P450DB1
cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) CYP2D6 protein results in increased metabolism of Eugenol increases metabolic processing
protein 15576237
D005054 1565 CYP2D6
CPD6
CYP2D
CYP2D7AP
CYP2D7BP
CYP2D7P2
CYP2D8P2
CYP2DL1
CYPIID6
P450-DB1
P450C2D
P450DB1
cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) [CYP2D6 protein results in increased metabolism of Eugenol] which results in increased abundance of 2-hydroxychavicol increases abundance
/ increases metabolic processing
protein 15576237
D005054 1565 CYP2D6
CPD6
CYP2D
CYP2D7AP
CYP2D7BP
CYP2D7P2
CYP2D8P2
CYP2DL1
CYPIID6
P450-DB1
P450C2D
P450DB1
cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) [Eugenol co-treated with Copper co-treated with CYP2D6 protein] results in increased abundance of 8-oxo-7-hydrodeoxyguanosine affects cotreatment
/ increases abundance
protein 15576237
D005054 1565 CYP2D6
CPD6
CYP2D
CYP2D7AP
CYP2D7BP
CYP2D7P2
CYP2D8P2
CYP2DL1
CYPIID6
P450-DB1
P450C2D
P450DB1
cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) methional inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol] affects cotreatment
/ decreases reaction
/ increases activity
protein 15576237
D005054 1571 CYP2E1
CPE1
CYP2E
P450-J
P450C2E
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) [CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol affects cotreatment
/ increases activity
protein 15576237
D005054 1736 DKC1
CBF5
DKC
DKCX
NAP57
NOLA4
XAP101
dyskeratosis congenita 1, dyskerin Eugenol results in decreased expression of DKC1 mRNA decreases expression
mRNA 17374397
D005054 9787 DLGAP5
DLG7
HURP
discs, large (Drosophila) homolog-associated protein 5 Eugenol results in decreased expression of DLGAP5 mRNA decreases expression
mRNA 17374397
D005054 1869 E2F1
E2F-1
RBAP1
RBBP3
RBP3
E2F transcription factor 1 Eugenol results in decreased expression of E2F1 mRNA decreases expression
mRNA 15574415
D005054 1869 E2F1
E2F-1
RBAP1
RBBP3
RBP3
E2F transcription factor 1 Eugenol results in decreased expression of E2F1 protein decreases expression
protein 15574415
D005054 1870 E2F2
E2F-2
E2F transcription factor 2 Eugenol results in decreased expression of E2F2 mRNA decreases expression
mRNA 15574415
D005054 1870 E2F2
E2F-2
E2F transcription factor 2 Eugenol results in decreased expression of E2F2 protein decreases expression
protein 15574415
D005054 1871 E2F3
E2F-3
E2F transcription factor 3 Eugenol results in decreased expression of E2F3 mRNA decreases expression
mRNA 15574415
D005054 1871 E2F3
E2F-3
E2F transcription factor 3 Eugenol results in decreased expression of E2F3 protein decreases expression
protein 15574415
D005054 1874 E2F4
E2F-4
E2F transcription factor 4, p107/p130-binding Eugenol results in decreased expression of E2F4 mRNA decreases expression
mRNA 15574415
D005054 1875 E2F5
E2F-5
E2F transcription factor 5, p130-binding Eugenol results in decreased expression of E2F5 mRNA decreases expression
mRNA 15574415
D005054 1876 E2F6
E2F-6
E2F transcription factor 6 Eugenol results in increased expression of E2F6 mRNA increases expression
mRNA 15574415
D005054 1959 EGR2
AT591
CMT1D
CMT4E
KROX20
early growth response 2 Eugenol results in decreased expression of EGR2 mRNA decreases expression
mRNA 17374397
D005054 133418 EMB
embigin Eugenol results in decreased expression of EMB mRNA decreases expression
mRNA 17374397
D005054 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Eugenol binds to ESR1 protein affects binding
protein 12495555
D005054 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Eugenol inhibits the reaction [Estradiol binds to ESR1 protein] affects binding
/ decreases reaction
protein 12495555
D005054 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Eugenol binds to ESR2 protein affects binding
protein 12495555
D005054 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Eugenol inhibits the reaction [Estradiol binds to ESR2 protein] affects binding
/ decreases reaction
protein 12495555
D005054 2162 F13A1
F13A
coagulation factor XIII, A1 polypeptide (EC:2.3.2.13) Eugenol results in decreased expression of F13A1 mRNA decreases expression
mRNA 17374397
D005054 26268 FBXO9
FBX9
NY-REN-57
VCIA1
dJ341E18.2
F-box protein 9 Eugenol results in decreased expression of FBXO9 mRNA decreases expression
mRNA 17374397
D005054 2213 FCGR2B
CD32
CD32B
FCG2
FCGR2
IGFR2
Fc fragment of IgG, low affinity IIb, receptor (CD32) Eugenol results in increased expression of FCGR2B mRNA increases expression
mRNA 17374397
D005054 2235 FECH
EPP
FCE
ferrochelatase (EC:4.99.1.1) Eugenol results in increased expression of FECH mRNA increases expression
mRNA 20566472
D005054 2355 FOSL2
FRA2
FOS-like antigen 2 Eugenol results in increased expression of FOSL2 mRNA increases expression
mRNA 17374397
D005054 2512 FTL
NBIA3
ferritin, light polypeptide Eugenol results in increased expression of FTL mRNA increases expression
mRNA 20566472
D005054 2539 G6PD
G6PD1
glucose-6-phosphate dehydrogenase (EC:1.1.1.49) Eugenol results in increased expression of G6PD mRNA increases expression
mRNA 20566472
D005054 2729 GCLC
GCL
GCS
GLCL
GLCLC
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) Eugenol results in increased expression of GCLC mRNA increases expression
mRNA 20566472
D005054 2730 GCLM
GLCLR
glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) Eugenol results in increased expression of GCLM mRNA increases expression
mRNA 20566472
D005054 644076 GLYCAM1
glycosylation dependent cell adhesion molecule 1 (pseudogene) Eugenol results in increased expression of GLYCAM1 mRNA increases expression
mRNA 17936526
D005054 2878 GPX3
GPx-P
GSHPx-3
GSHPx-P
glutathione peroxidase 3 (plasma) (EC:1.11.1.9) Eugenol results in increased expression of GPX3 mRNA increases expression
mRNA 20566472
D005054 2932 GSK3B
glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) Eugenol results in increased expression of GSK3B mRNA increases expression
mRNA 17374397
D005054 2936 GSR
glutathione reductase (EC:1.8.1.7) Eugenol results in increased expression of GSR mRNA increases expression
mRNA 20566472
D005054 2938 GSTA1
GST2
GSTA1-1
GTH1
glutathione S-transferase alpha 1 (EC:2.5.1.18) Eugenol analog results in decreased activity of GSTA1 protein decreases activity
protein 8620581
D005054 2944 GSTM1
GST1
GSTM1-1
GSTM1a-1a
GSTM1b-1b
GTH4
GTM1
H-B
MU
MU-1
glutathione S-transferase mu 1 (EC:2.5.1.18) Eugenol analog results in decreased activity of GSTM1 protein decreases activity
protein 8620581
D005054 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) Eugenol analog results in decreased activity of GSTP1 protein decreases activity
protein 8620581
D005054 2994 GYPB
CD235b
GPB
GPB.NY
GYPHe.NY
GpMiIII
HGpMiIII
HGpMiVI
HGpMiX
MNS
PAS-3
SS
glycophorin B (MNS blood group) Eugenol results in decreased expression of GYPB mRNA decreases expression
mRNA 17374397
D005054 54497 HEATR5B
HEAT repeat containing 5B Eugenol results in decreased expression of HEATR5B mRNA decreases expression
mRNA 17374397
D005054 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Eugenol results in increased expression of HIF1A mRNA increases expression
mRNA 20713136
D005054 3106 HLA-B
AS
HLAB
SPDA1
major histocompatibility complex, class I, B Eugenol results in increased expression of HLA-B mRNA increases expression
mRNA 17374397
D005054 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Eugenol results in increased expression of HMOX1 mRNA increases expression
mRNA 20566472
20713136
D005054 220988 HNRNPA3
2610510D13Rik
D10S102
FBRNP
HNRPA3
heterogeneous nuclear ribonucleoprotein A3 Eugenol results in decreased expression of HNRNPA3 mRNA decreases expression
mRNA 17374397
D005054 3381 IBSP
BNSP
BSP
BSP-II
SP-II
integrin-binding sialoprotein Eugenol results in decreased expression of IBSP mRNA decreases expression
mRNA 21706355
D005054 3381 IBSP
BNSP
BSP
BSP-II
SP-II
integrin-binding sialoprotein Eugenol results in decreased expression of IBSP protein decreases expression
protein 21706355
D005054 3422 IDI1
IPP1
IPPI1
isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2) Eugenol results in decreased expression of IDI1 mRNA decreases expression
mRNA 17374397
D005054 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 21807015
D005054 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein] decreases reaction
/ increases expression
/ increases secretion
protein 17509409
D005054 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] decreases reaction
/ increases expression
mRNA 17509409
D005054 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Eugenol results in decreased expression of IL1B mRNA decreases expression
mRNA 21939359
D005054 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta [Eugenol results in increased activity of sulforafan] which results in decreased expression of IL1B decreases expression
/ increases activity
21382956
D005054 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Eugenol results in increased expression of IL1B mRNA increases expression
mRNA 20713136
D005054 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta [sulforafan results in increased activity of Eugenol] which results in decreased expression of IL1B decreases expression
/ increases activity
21382956
D005054 7850 IL1R2
CD121b
CDw121b
IL-1R-2
IL-1RT-2
IL-1RT2
IL1R2c
IL1RB
interleukin 1 receptor, type II Eugenol results in increased expression of IL1R2 mRNA increases expression
mRNA 20713136
D005054 3575 IL7R
CD127
CDW127
IL-7R-alpha
IL7RA
ILRA
interleukin 7 receptor Eugenol results in increased expression of IL7R mRNA increases expression
mRNA 20713136
D005054 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Acetylcysteine inhibits the reaction [Eugenol results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
mRNA 21920952
D005054 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Eugenol results in increased expression of IL8 mRNA increases expression
mRNA 20713136
21920952
D005054 26034 IPCEF1
PIP3-E
RP3-402L9.2
interaction protein for cytohesin exchange factors 1 Eugenol results in decreased expression of IPCEF1 mRNA decreases expression
mRNA 17374397
D005054 3655 ITGA6
CD49f
ITGA6B
VLA-6
integrin, alpha 6 Eugenol results in increased expression of ITGA6 mRNA increases expression
mRNA 17936526
D005054 3688 ITGB1
CD29
FNRB
GPIIA
MDF2
MSK12
VLA-BETA
VLAB
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) Eugenol results in increased expression of ITGB1 mRNA increases expression
mRNA 17936526
D005054 3741 KCNA5
ATFB7
HCK1
HK2
HPCN1
KV1.5
PCN1
potassium voltage-gated channel, shaker-related subfamily, member 5 Eugenol results in decreased activity of KCNA5 protein decreases activity
protein 17720863
D005054 3759 KCNJ2
ATFB9
HHBIRK1
HHIRK1
IRK1
KIR2.1
LQT7
SQT3
potassium inwardly-rectifying channel, subfamily J, member 2 Eugenol results in decreased expression of KCNJ2 mRNA decreases expression
mRNA 17374397
D005054 9493 KIF23
CHO1
KNSL5
MKLP-1
MKLP1
kinesin family member 23 Eugenol results in decreased expression of KIF23 mRNA decreases expression
mRNA 17374397
D005054 23764 MAFF
U-MAF
hMafF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F Eugenol results in increased expression of MAFF mRNA increases expression
mRNA 20566472
D005054 4097 MAFG
hMAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G Eugenol results in increased expression of MAFG mRNA increases expression
mRNA 20566472
D005054 7975 MAFK
NFE2U
P18
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K Eugenol results in increased expression of MAFK mRNA increases expression
mRNA 20566472
D005054 28985 MCTS1
MCT-1
MCT1
malignant T cell amplified sequence 1 Eugenol results in decreased expression of MCTS1 mRNA decreases expression
mRNA 17374397
D005054 4199 ME1
HUMNDME
MES
malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) Eugenol results in increased expression of ME1 mRNA increases expression
mRNA 20566472
D005054 4257 MGST1
GST12
MGST
MGST-I
microsomal glutathione S-transferase 1 (EC:2.5.1.18) Eugenol results in increased expression of MGST1 mRNA increases expression
mRNA 20566472
D005054 51318 MRPL35
L35mt
MRP-L35
mitochondrial ribosomal protein L35 Eugenol results in decreased expression of MRPL35 mRNA decreases expression
mRNA 17374397
D005054 58475 MS4A7
4SPAN2
CD20L4
CFFM4
MS4A8
membrane-spanning 4-domains, subfamily A, member 7 Eugenol results in increased expression of MS4A7 mRNA increases expression
mRNA 17374397
D005054 4501 MT1X
MT-1l
MT1
metallothionein 1X Eugenol results in increased expression of MT1X mRNA increases expression
mRNA 20566472
D005054 4084 MXD1
BHLHC58
MAD
MAD1
MAX dimerization protein 1 Eugenol results in increased expression of MXD1 mRNA increases expression
mRNA 20713136
D005054 4602 MYB
Cmyb
c-myb
c-myb_CDS
efg
v-myb avian myeloblastosis viral oncogene homolog Eugenol results in decreased expression of MYB mRNA decreases expression
mRNA 17374397
D005054 10135 NAMPT
1110035O14Rik
PBEF
PBEF1
VF
VISFATIN
nicotinamide phosphoribosyltransferase (EC:2.4.2.12) Eugenol results in increased expression of NAMPT mRNA increases expression
mRNA 17374397
D005054 4780 NFE2L2
NRF2
nuclear factor, erythroid 2-like 2 Eugenol affects the expression of NFE2L2 protein affects expression
protein 17275817
D005054 4780 NFE2L2
NRF2
nuclear factor, erythroid 2-like 2 Eugenol promotes the reaction [NFE2L2 protein results in increased expression of NQO1 mRNA] increases expression
/ increases reaction
protein 17275817
D005054 4790 NFKB1
EBP-1
KBF1
NF-kB1
NF-kappa-B
NF-kappaB
NFKB-p105
NFKB-p50
NFkappaB
p105
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Eugenol affects the expression of NFKB1 mRNA affects expression
mRNA 20385217
D005054 4790 NFKB1
EBP-1
KBF1
NF-kB1
NF-kappa-B
NF-kappaB
NFKB-p105
NFKB-p50
NFkappaB
p105
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]] affects binding
/ decreases reaction
/ increases activity
protein 10871845
D005054 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) [Dicumarol results in decreased activity of NQO1 protein] inhibits the reaction [Eugenol results in increased expression of CD86 protein] decreases activity
/ decreases reaction
/ increases expression
protein 21742781
D005054 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) Eugenol promotes the reaction [NFE2L2 protein results in increased expression of NQO1 mRNA] increases expression
/ increases reaction
mRNA 17275817
D005054 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) Eugenol results in increased activity of NQO1 protein increases activity
protein 17275817
D005054 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) Eugenol results in increased expression of NQO1 mRNA increases expression
mRNA 20566472
D005054 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) Eugenol results in increased expression of NQO1 protein increases expression
protein 17275817
D005054 4927 NUP88
nucleoporin 88kDa Eugenol results in increased expression of NUP88 mRNA increases expression
mRNA 17374397
D005054 10606 PAICS
ADE2
ADE2H1
AIRC
PAIS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (EC:6.3.2.6 4.1.1.21) Eugenol results in decreased expression of PAICS mRNA decreases expression
mRNA 17374397
D005054 5142 PDE4B
DPDE4
PDE4B5
PDEIVB
phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) Eugenol results in increased expression of PDE4B mRNA increases expression
mRNA 17374397
D005054 5226 PGD
6PGD
phosphogluconate dehydrogenase (EC:1.1.1.44) Eugenol results in increased expression of PGD mRNA increases expression
mRNA 20566472
D005054 8301 PICALM
CALM
CLTH
LAP
phosphatidylinositol binding clathrin assembly protein Eugenol results in increased expression of PICALM mRNA increases expression
mRNA 17374397
D005054 5327 PLAT
T-PA
TPA
plasminogen activator, tissue (EC:3.4.21.68) Eugenol results in increased expression of PLAT mRNA increases expression
mRNA 17374397
D005054 5366 PMAIP1
APR
NOXA
phorbol-12-myristate-13-acetate-induced protein 1 Eugenol results in increased expression of PMAIP1 mRNA increases expression
mRNA 20713136
D005054 5468 PPARG
CIMT1
GLM1
NR1C3
PPARG1
PPARG2
PPARgamma
peroxisome proliferator-activated receptor gamma Eugenol analog binds to and results in increased activity of PPARG protein affects binding
/ increases activity
protein 20064974
D005054 10935 PRDX3
AOP-1
AOP1
HBC189
MER5
PRO1748
SP-22
prx-III
peroxiredoxin 3 (EC:1.11.1.15) Eugenol results in decreased expression of PRDX3 mRNA decreases expression
mRNA 17374397
D005054 5733 PTGER3
EP3
EP3-I
EP3-II
EP3-III
EP3-IV
EP3e
PGE2-R
prostaglandin E receptor 3 (subtype EP3) Eugenol results in decreased expression of PTGER3 mRNA decreases expression
mRNA 17374397
D005054 22949 PTGR1
LTB4DH
PGR1
ZADH3
prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) Eugenol results in increased expression of PTGR1 mRNA increases expression
mRNA 20566472
D005054 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 21807015
D005054 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 21807015
D005054 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] decreases reaction
/ increases expression
mRNA 17509409
D005054 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Eugenol results in decreased expression of PTGS2 mRNA decreases expression
mRNA 12757841
21939359
D005054 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]] affects binding
/ decreases reaction
/ increases activity
protein 10871845
D005054 5996 RGS1
1R20
BL34
IER1
IR20
regulator of G-protein signaling 1 Eugenol results in increased expression of RGS1 mRNA increases expression
mRNA 17374397
20713136
D005054 6157 RPL27A
L27A
ribosomal protein L27a Eugenol results in increased expression of RPL27A mRNA increases expression
mRNA 17374397
D005054 50484 RRM2B
MTDPS8A
MTDPS8B
P53R2
ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1) Eugenol results in increased expression of RRM2B mRNA increases expression
mRNA 21704725
D005054 6303 SAT1
DC21
KFSD
KFSDX
SAT
SSAT
SSAT-1
spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) Eugenol results in increased expression of SAT1 mRNA increases expression
mRNA 17374397
D005054 6383 SDC2
CD362
HSPG
HSPG1
SYND2
syndecan 2 Eugenol results in increased expression of SDC2 mRNA increases expression
mRNA 17374397
D005054 55752 SEPT11
septin 11 Eugenol results in decreased expression of SEPT11 mRNA decreases expression
mRNA 17374397
D005054 6504 SLAMF1
CD150
CDw150
SLAM
signaling lymphocytic activation molecule family member 1 Eugenol results in decreased expression of SLAMF1 mRNA decreases expression
mRNA 20713136
D005054 117247 SLC16A10
MCT10
PRO0813
TAT1
solute carrier family 16 (aromatic amino acid transporter), member 10 Eugenol results in increased expression of SLC16A10 mRNA increases expression
mRNA 17374397
D005054 6515 SLC2A3
GLUT3
solute carrier family 2 (facilitated glucose transporter), member 3 Eugenol results in increased expression of SLC2A3 mRNA increases expression
mRNA 17374397
D005054 6647 SOD1
ALS
ALS1
IPOA
SOD
hSod1
homodimer
superoxide dismutase 1, soluble (EC:1.15.1.1) Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA] decreases expression
/ increases reaction
mRNA 16101137
D005054 6647 SOD1
ALS
ALS1
IPOA
SOD
hSod1
homodimer
superoxide dismutase 1, soluble (EC:1.15.1.1) Eugenol results in decreased expression of SOD1 mRNA decreases expression
mRNA 16101137
D005054 6647 SOD1
ALS
ALS1
IPOA
SOD
hSod1
homodimer
superoxide dismutase 1, soluble (EC:1.15.1.1) Eugenol results in decreased expression of SOD1 protein decreases expression
protein 16101137
D005054 6647 SOD1
ALS
ALS1
IPOA
SOD
hSod1
homodimer
superoxide dismutase 1, soluble (EC:1.15.1.1) Eugenol results in increased expression of SOD1 mRNA increases expression
mRNA 20566472
D005054 6647 SOD1
ALS
ALS1
IPOA
SOD
hSod1
homodimer
superoxide dismutase 1, soluble (EC:1.15.1.1) Glutathione promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA] decreases expression
/ increases reaction
mRNA 16101137
D005054 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA] decreases expression
/ increases reaction
mRNA 16101137
D005054 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Eugenol results in decreased expression of SOD2 mRNA decreases expression
mRNA 16101137
D005054 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Eugenol results in decreased expression of SOD2 protein decreases expression
protein 16101137
D005054 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Eugenol results in increased expression of SOD2 mRNA increases expression
mRNA 20566472
D005054 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Glutathione promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA] decreases expression
/ increases reaction
mRNA 16101137
D005054 6649 SOD3
EC-SOD
superoxide dismutase 3, extracellular (EC:1.15.1.1) Eugenol results in increased expression of SOD3 mRNA increases expression
mRNA 20566472
D005054 140809 SRXN1
C20orf139
Npn3
SRX
SRX1
sulfiredoxin 1 (EC:1.8.98.2) Eugenol results in increased expression of SRXN1 mRNA increases expression
mRNA 20566472
D005054 6772 STAT1
CANDF7
ISGF-3
STAT91
signal transducer and activator of transcription 1, 91kDa Eugenol results in decreased expression of STAT1 mRNA decreases expression
mRNA 17374397
D005054 6775 STAT4
SLEB11
signal transducer and activator of transcription 4 Eugenol results in increased expression of STAT4 mRNA increases expression
mRNA 17374397
D005054 6777 STAT5B
STAT5
signal transducer and activator of transcription 5B Eugenol results in increased expression of STAT5B mRNA increases expression
mRNA 17374397
D005054 7099 TLR4
ARMD10
CD284
TLR-4
TOLL
toll-like receptor 4 Eugenol results in increased expression of TLR4 mRNA increases expression
mRNA 17936526
D005054 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Eugenol affects the expression of TNF mRNA affects expression
mRNA 20385217
D005054 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 21807015
D005054 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein] decreases reaction
/ increases expression
/ increases secretion
protein 17509409
D005054 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] decreases reaction
/ increases expression
mRNA 17509409
D005054 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]] affects binding
/ decreases reaction
/ increases activity
protein 10871845
D005054 7128 TNFAIP3
A20
OTUD7C
TNFA1P2
tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) Eugenol results in increased expression of TNFAIP3 mRNA increases expression
mRNA 20713136
D005054 7130 TNFAIP6
TSG-6
TSG6
tumor necrosis factor, alpha-induced protein 6 Eugenol results in increased expression of TNFAIP6 mRNA increases expression
mRNA 17374397
20713136
D005054 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Eugenol results in increased mutagenesis of TP53 gene increases mutagenesis
gene 15576237
D005054 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 Eugenol results in decreased expression of TP63 mRNA decreases expression
mRNA 17936526
D005054 162514 TRPV3
OLMS
VRL3
transient receptor potential cation channel, subfamily V, member 3 Eugenol binds to and results in increased activity of TRPV3 protein affects binding
/ increases activity
protein 21593771
D005054 25828 TXN2
MT-TRX
MTRX
TRX2
thioredoxin 2 Eugenol results in increased expression of TXN2 mRNA increases expression
mRNA 20566472
D005054 7296 TXNRD1
GRIM-12
TR
TR1
TRXR1
TXNR
thioredoxin reductase 1 (EC:1.8.1.9) Eugenol results in increased expression of TXNRD1 mRNA increases expression
mRNA 20566472
D005054 10587 TXNRD2
SELZ
TR
TR-BETA
TR3
TRXR2
thioredoxin reductase 2 (EC:1.8.1.9) Eugenol results in increased expression of TXNRD2 mRNA increases expression
mRNA 20566472
D005054 7358 UGDH
GDH
UDP-GlcDH
UDPGDH
UGD
UDP-glucose 6-dehydrogenase (EC:1.1.1.22) Eugenol results in increased expression of UGDH mRNA increases expression
mRNA 16292757
D005054 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) UGT1A1 protein results in increased glucuronidation of Eugenol increases glucuronidation
protein 14557274
D005054 54575 UGT1A10
UDPGT
UGT-1J
UGT1-10
UGT1.10
UGT1J
UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) UGT1A10 protein results in increased glucuronidation of Eugenol increases glucuronidation
protein 14557274
D005054 54578 UGT1A6
GNT1
HLUGP
HLUGP1
UDPGT
UDPGT_1-6
UGT1
UGT1A6S
UGT1F
UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) Eugenol results in increased expression of UGT1A6 mRNA increases expression
mRNA 20566472
D005054 54577 UGT1A7
UDPGT
UDPGT_1-7
UGT-1G
UGT1-07
UGT1.7
UGT1G
UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) UGT1A7 protein results in increased glucuronidation of Eugenol increases glucuronidation
protein 14557274
D005054 54576 UGT1A8
UDPGT
UDPGT_1-8
UGT-1H
UGT1-08
UGT1.8
UGT1A8S
UGT1H
UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) UGT1A8 protein results in increased glucuronidation of Eugenol increases glucuronidation
protein 14557274
D005054 54600 UGT1A9
HLUGP4
LUGP4
UDPGT
UDPGT_1-9
UGT-1I
UGT1-09
UGT1-9
UGT1.9
UGT1AI
UGT1I
UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) UGT1A9 protein results in increased glucuronidation of Eugenol increases glucuronidation
protein 14557274
D005054 7366 UGT2B15
HLUG4
UDPGT_2B8
UDPGT2B15
UDPGTH3
UGT2B8
UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) UGT2B15 protein results in increased metabolism of Eugenol increases metabolic processing
protein 7835232
D005054 7366 UGT2B15
HLUG4
UDPGT_2B8
UDPGT2B15
UDPGTH3
UGT2B8
UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) UGT2B15 protein SNP results in increased metabolism of Eugenol increases metabolic processing
protein 12386133
D005054 7367 UGT2B17
BMND12
UDPGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17) UGT2B17 protein results in increased metabolism of Eugenol increases metabolic processing
protein 8798464
D005054 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Eugenol results in increased expression of VDR mRNA increases expression
mRNA 17374397
D005054 7709 ZBTB17
MIZ-1
ZNF151
ZNF60
pHZ-67
zinc finger and BTB domain containing 17 Eugenol results in decreased expression of ZBTB17 mRNA decreases expression
mRNA 17374397

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (45)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#612560 Bone mineral density quantitative trait locus 12; bmnd12 O75795
#300615 Brunner syndrome P21397
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137800 Glioma susceptibility 1; glm1 P04626
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#603932 Intervertebral disc disease; idd P14780
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#126200 Multiple sclerosis, susceptibility to; ms P08575
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#607276 Resting heart rate, variation in P08588
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (36)

KEGG disease name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

28 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D001943 D005054 Breast Neoplasms therapeutic
17275817
D017449 D005054 Dermatitis, Allergic Contact marker/mechanism
17374397
22245253
22564262
D003877 D005054 Dermatitis, Contact marker/mechanism
12423654
D003875 D005054 Drug Eruptions marker/mechanism
22381623
D056486 D005054 Drug-Induced Liver Injury therapeutic
20036707
D006331 D005054 Heart Diseases therapeutic
21656368
D006461 D005054 Hemolysis therapeutic
20639367
D006930 D005054 Hyperalgesia therapeutic
19376653
D006967 D005054 Hypersensitivity marker/mechanism
15585374
D007249 D005054 Inflammation therapeutic
17509409
D008545 D005054 Melanoma therapeutic
15574415
D009361 D005054 Neoplasm Invasiveness therapeutic
15574415
20434464
D009362 D005054 Neoplasm Metastasis therapeutic
15574415
D009374 D005054 Neoplasms, Experimental therapeutic
19851710
20043298
20434464
D009389 D005054 Neovascularization, Pathologic therapeutic
20434464
D009410 D005054 Nerve Degeneration therapeutic
9147382
D010146 D005054 Pain therapeutic
9126180
19967073
21547684
D010149 D005054 Pain, Postoperative therapeutic
2061421
D010300 D005054 Parkinson Disease therapeutic
17329831
D011833 D005054 Radiation Injuries, Experimental therapeutic
15613789
D012481 D005054 Salmonella Infections, Animal therapeutic
22327574
D012878 D005054 Skin Neoplasms therapeutic
20043298
20537511
D013035 D005054 Spasm therapeutic
21077946
D013203 D005054 Staphylococcal Infections therapeutic
20639367
D013274 D005054 Stomach Neoplasms therapeutic
19851710
20434464
D013276 D005054 Stomach Ulcer therapeutic
18543354
D014581 D005054 Urticaria therapeutic
6693599
D002583 D005054 Uterine Cervical Neoplasms therapeutic
21382956
21939359