Species

KNApSAcK Entry

Organism name Origanum majorana
Genus Origanum
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Origanum majorana
Linked NCBI taxonomy ID 268884
Linked level species

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (22)

Species Activity
Origanum majorana L. Allergenic
Origanum majorana L. Analgesic
Origanum majorana L. Antibacterial
Origanum majorana L. Anticancer
Origanum majorana L. Anticonvulsant
Origanum majorana L. Antiherpetic
Origanum majorana L. Antioxidant
Origanum majorana L. Antiseptic
Origanum majorana L. Antispasmodic
Origanum majorana L. Antiviral
Origanum majorana L. Aphrodisiac
Origanum majorana L. Carminative
Origanum majorana L. COX-2 Inhibitor
Origanum majorana L. Dermatitigenic
Origanum majorana L. Diaphoretic
Origanum majorana L. Digestive
Origanum majorana L. Diuretic
Origanum majorana L. Expectorant
Origanum majorana L. Fungicide
Origanum majorana L. Insecticide
Origanum majorana L. Sedative
Origanum majorana L. Tranquilizer

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002638 External link 512 Arbutin
CHEMBL226495
CHEMBL232202
CHEMBL1357990
D001104
5 / 7 / 5 282 / 0 No. 45 No. 72
C00000619 External link 512 Eugenol
CHEMBL42710
D005054
103 / 45 / 36 152 / 28 No. 1852 No. 6
C00003060 External link 512 alpha-Terpinene
No. 2468 No. 35

Human Protein / Gene in interactions

107 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000619 C00002638 0 / 3
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00000619 0 / 0
O75795 UDP-glucuronosyltransferase 2B17 Enzyme C00000619 1 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00000619 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00000619 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000619 1 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00000619 2 / 2
P08246 Neutrophil elastase S1A C00000619 2 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00000619 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00000619 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00000619 0 / 0
P29466 Caspase-1 C14 C00000619 0 / 0
P17252 Protein kinase C alpha type Alpha C00000619 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00000619 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00000619 2 / 2
P00918 Carbonic anhydrase 2 Lyase C00000619 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00000619 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00000619 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00000619 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00000619 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00000619 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00000619 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00000619 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00000619 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00000619 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00000619 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00000619 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000619 0 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000619 1 / 8
P14416 D(2) dopamine receptor Dopamine receptor C00000619 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000619 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00000619 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00000619 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00000619 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00000619 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00000619 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00000619 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00000619 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00000619 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00000619 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00000619 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002638 2 / 0
O75496 Geminin Unclassified protein C00000619 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00000619 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00000619 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00000619 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00000619 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00000619 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00000619 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00000619 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00000619 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00000619 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00000619 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00000619 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00000619 0 / 0
P10145 Interleukin-8 Secreted protein C00000619 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00000619 1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00000619 0 / 0
P08311 Cathepsin G S1A C00000619 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00000619 1 / 0
P03956 Interstitial collagenase M10A C00000619 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00000619 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00000619 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00000619 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00000619 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00000619 0 / 0
P14679 Tyrosinase Oxidoreductase C00002638 4 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00000619 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00000619 2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00000619 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00000619 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00000619 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00000619 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00000619 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00000619 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00000619 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00000619 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00000619 2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000619 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00000619 3 / 0
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00000619 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00000619 0 / 0
P03372 Estrogen receptor NR3A1 C00000619 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00000619 1 / 0
P22303 Acetylcholinesterase Hydrolase C00000619 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00000619 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00000619 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00000619 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00000619 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00000619 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00000619 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00000619 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000619 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000619 0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00000619 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00000619 5 / 1
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00000619 0 / 0
P10275 Androgen receptor NR3C4 C00000619 3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00000619 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00000619 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00000619 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00000619 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00000619 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00000619 0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00000619 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002638 1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002638 0 / 0

433 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
7975 MAFK, NFE2U, P18 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K C00000619 C00002638
4602 MYB, Cmyb, c-myb, c-myb_CDS, efg v-myb avian myeloblastosis viral oncogene homolog C00000619
150000 ABCC13, C21orf73, PRED6 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene C00002638
130013 ACMSD aminocarboxymuconate semialdehyde decarboxylase (EC:4.1.1.45) C00002638
94 ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I activin A receptor type II-like 1 (EC:2.7.11.30) C00002638
8728 ADAM19, MADDAM, MLTNB ADAM metallopeptidase domain 19 C00002638
8748 ADAM20 ADAM metallopeptidase domain 20 C00002638
8756 ADAM7, ADAM_7, ADAM-7, EAPI, GP-83, GP83 ADAM metallopeptidase domain 7 C00002638
9508 ADAMTS3, ADAMTS-4 ADAM metallopeptidase with thrombospondin type 1 motif, 3 (EC:3.4.24.-) C00002638
56999 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 C00002638
155 ADRB3, BETA3AR adrenoceptor beta 3 C00002638
121536 AEBP2 AE binding protein 2 C00002638
60312 AFAP1, AFAP, AFAP-110, AFAP110 actin filament associated protein 1 C00002638
84871 AGBL4, CCP6 ATP/GTP binding protein-like 4 C00002638
56894 AGPAT3, LPAAT-GAMMA1, LPAAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 (EC:2.3.1.51) C00002638
79026 AHNAK, AHNAKRS AHNAK nucleoprotein C00002638
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002638
401138 AMTN, UNQ689 amelotin C00002638
26057 ANKRD17, GTAR, NY-BR-16 ankyrin repeat domain 17 C00002638
200539 ANKRD23, DARP, MARP3 ankyrin repeat domain 23 C00002638
1174 AP1S1, AP19, CLAPS1, MEDNIK, SIGMA1A, WUGSC:H_DJ0747G18.2 adaptor-related protein complex 1, sigma 1 subunit C00002638
55937 APOM, G3a, HSPC336, NG20, apo-M apolipoprotein M C00002638
54840 APTX, AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT aprataxin C00002638
23647 ARFIP2, POR1 ADP-ribosylation factor interacting protein 2 C00002638
9181 ARHGEF2, GEF, GEF-H1, GEFH1, LFP40, P40 Rho/Rac guanine nucleotide exchange factor (GEF) 2 C00002638
402 ARL2, ARFL2 ADP-ribosylation factor-like 2 C00002638
23204 ARL6IP1, AIP1, ARL6IP, ARMER ADP-ribosylation factor-like 6 interacting protein 1 C00002638
170302 ARX, CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS aristaless related homeobox C00002638
55616 ASAP3, ACAP4, CENTB6, DDEFL1, UPLC1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 C00002638
439 ASNA1, ARSA-I, ARSA1, ASNA-I, GET3, TRC40, hASNA-I arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (EC:3.6.3.16) C00002638
83858 ATAD3B, AAA-TOB3, TOB3 ATPase family, AAA domain containing 3B C00002638
1388 ATF6B, CREB-RP, CREBL1, G13 activating transcription factor 6 beta C00002638
338707 B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 (EC:2.4.1.244) C00002638
9529 BAG5, BAG-5 BCL2-associated athanogene 5 C00002638
10286 BCAS2, DAM1, SPF27, Snt309 breast carcinoma amplified sequence 2 C00002638
10295 BCKDK, BCKDKD, BDK branched chain ketoacid dehydrogenase kinase (EC:2.7.11.4) C00002638
658 BMPR1B, ALK-6, ALK6, CDw293 bone morphogenetic protein receptor, type IB (EC:2.7.11.30) C00002638
663 BNIP2, BNIP-2, NIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 C00002638
84446 BRSK1, hSAD1 BR serine/threonine kinase 1 (EC:2.7.11.1 2.7.11.26) C00002638
684 BST2, CD317, TETHERIN bone marrow stromal cell antigen 2 C00002638
11120 BTN2A1, BK14H9.1, BT2.1, BTF1, DJ3E1.1 butyrophilin, subfamily 2, member A1 C00002638
9256 BZRAP1, PBR-IP, PRAX-1, PRAX1, RIM-BP1, RIMBP1 benzodiazapine receptor (peripheral) associated protein 1 C00002638
161502 C15orf26 chromosome 15 open reading frame 26 C00002638
84529 C15orf41, HH114 chromosome 15 open reading frame 41 C00002638
64073 C19orf33, H2RSP, IMUP, IMUP-1, IMUP-2 chromosome 19 open reading frame 33 C00002638
84808 C1orf170, RP11-54O7.8 chromosome 1 open reading frame 170 C00002638
10485 C1orf61, CROC4 chromosome 1 open reading frame 61 C00002638
127795 C1orf87 chromosome 1 open reading frame 87 C00002638
713 C1QB complement component 1, q subcomponent, B chain C00002638
59284 CACNG7 calcium channel, voltage-dependent, gamma subunit 7 C00002638
84290 CAPNS2 calpain, small subunit 2 C00002638
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002638
23466 CBX6 chromobox homolog 6 C00002638
55749 CCAR1, RP11-437A18.1 cell division cycle and apoptosis regulator 1 C00002638
80129 CCDC170, C6orf97, bA282P11.1 coiled-coil domain containing 170 C00002638
79140 CCDC28B, RP4-622L5.5 coiled-coil domain containing 28B C00002638
151195 CCNYL1 cyclin Y-like 1 C00002638
10694 CCT8, C21orf112, Cctq, D21S246, PRED71 chaperonin containing TCP1, subunit 8 (theta) C00002638
977 CD151, GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24 CD151 molecule (Raph blood group) C00002638
11126 CD160, BY55, NK1, NK28 CD160 molecule C00002638
283316 CD163L1, CD163B, M160 CD163 molecule-like 1 C00002638
10421 CD2BP2, FWP010, LIN1, PPP1R59, Snu40, U5-52K CD2 (cytoplasmic tail) binding protein 2 C00002638
917 CD3G, CD3-GAMMA, T3G CD3g molecule, gamma (CD3-TCR complex) C00002638
5127 CDK16, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1 cyclin-dependent kinase 16 (EC:2.7.11.22) C00002638
634 CEACAM1, BGP, BGP1, BGPI carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) C00002638
170482 CLEC4C, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150 C-type lectin domain family 4, member C C00002638
22866 CNKSR2, CNK2, KSR2, MAGUIN connector enhancer of kinase suppressor of Ras 2 C00002638
1308 COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1 collagen, type XVII, alpha 1 C00002638
1360 CPB1, CPB, PASP, PCPB carboxypeptidase B1 (tissue) (EC:3.4.17.2) C00002638
1363 CPE carboxypeptidase E (EC:3.4.17.10) C00002638
57699 CPNE5, COPN5, CPN5 copine V C00002638
113612 CYP2U1, P450TEC, SPG49, SPG56 cytochrome P450, family 2, subfamily U, polypeptide 1 (EC:1.14.14.1) C00002638
326709 C00002638
9879 DDX46, PRPF5, Prp5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 (EC:3.6.4.13) C00002638
1730 DIAPH2, DIA, DIA2, DRF2, POF, POF2 diaphanous-related formin 2 C00002638
22839 DLGAP4, DAP4, DLP4, RP5-977B1.6, SAPAP4 discs, large (Drosophila) homolog-associated protein 4 C00002638
1745 DLX1 distal-less homeobox 1 C00002638
1657 DMXL1 Dmx-like 1 C00002638
56171 DNAH7 dynein, axonemal, heavy chain 7 C00002638
4189 DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049 DnaJ (Hsp40) homolog, subfamily B, member 9 C00002638
29952 DPP7, DPP2, DPPII, QPP dipeptidyl-peptidase 7 (EC:3.4.14.2) C00002638
1808 DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2 dihydropyrimidinase-like 2 C00002638
1889 ECE1, ECE endothelin converting enzyme 1 (EC:3.4.24.71) C00002638
80820 EEPD1, HSPC107 endonuclease/exonuclease/phosphatase family domain containing 1 C00002638
80258 EFHC2, dJ1158H2.1 EF-hand domain (C-terminal) containing 2 C00002638
1944 EFNA3, EFL2, EPLG3, Ehk1-L, LERK3 ephrin-A3 C00002638
10278 EFS, CAS3, CASS3, EFS1, EFS2, HEFS, SIN embryonal Fyn-associated substrate C00002638
79631 EFTUD1, FAM42A, HsT19294, RIA1 elongation factor Tu GTP binding domain containing 1 C00002638
23741 EID1, C15orf3, CRI1, EID-1, IRO45620, PTD014, RBP21 EP300 interacting inhibitor of differentiation 1 C00002638
1991 ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1 elastase, neutrophil expressed (EC:3.4.21.37) C00002638
2018 EMX2 empty spiracles homeobox 2 C00002638
5167 ENPP1, ARHR2, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9) C00002638
2059 EPS8 epidermal growth factor receptor pathway substrate 8 C00002638
8288 EPX, EPO, EPP, EPX-PEN eosinophil peroxidase (EC:1.11.1.7) C00002638
23085 ERC1, Cast2, ELKS, RAB6IP2 ELKS/RAB6-interacting/CAST family member 1 C00002638
711 ERC2-IT1, C1orf1, C3orf51, Po42 ERC2 intronic transcript 1 (non-protein coding) C00002638
2124 EVI2B, CD361, D17S376, EVDB ecotropic viral integration site 2B C00002638
161829 EXD1, EXDL1 exonuclease 3'-5' domain containing 1 C00002638
2165 F13B, FXIIIB coagulation factor XIII, B polypeptide (EC:2.3.2.13) C00002638
131177 FAM3D, EF7, OIT1 family with sequence similarity 3, member D C00002638
51571 FAM49B, L1 family with sequence similarity 49, member B C00002638
115795 FANCD2OS, C3orf24 FANCD2 opposite strand C00002638
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002638
80204 FBXO11, FBX11, PRMT9, UBR6, VIT1 F-box protein 11 C00002638
157574 FBXO16, FBX16 F-box protein 16 C00002638
2250 FGF5, HBGF-5, Smag-82 fibroblast growth factor 5 C00002638
2261 FGFR3, ACH, CD333, CEK2, HSFGFR3EX, JTK4 fibroblast growth factor receptor 3 (EC:2.7.10.1) C00002638
91010 FMNL3, FHOD3, WBP-3, WBP3 formin-like 3 C00002638
8790 FPGT, GFPP fucose-1-phosphate guanylyltransferase (EC:2.7.7.30) C00002638
80144 FRAS1 Fraser syndrome 1 C00002638
9758 FRMPD4, PDZD10, PDZK10 FERM and PDZ domain containing 4 C00002638
2581 GALC galactosylceramidase (EC:3.2.1.46) C00002638
64762 GAREM, C18orf11, FAM59A, Gm944 GRB2 associated, regulator of MAPK1 C00002638
10755 GIPC1, C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2 GIPC PDZ domain containing family, member 1 C00002638
83468 GLT8D2 glycosyltransferase 8 domain containing 2 C00002638
2766 GMPR, GMPR1 guanosine monophosphate reductase (EC:1.7.1.7) C00002638
29889 GNL2, HUMAUANTIG, NGP1, Ngp-1 guanine nucleotide binding protein-like 2 (nucleolar) C00002638
2719 GPC3, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 glypican 3 C00002638
2820 GPD2, GDH2, GPDM, mGPDH glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (EC:1.1.5.3) C00002638
151556 GPR155, DEP.7, DEPDC3, PGR22 G protein-coupled receptor 155 C00002638
2849 GPR26 G protein-coupled receptor 26 C00002638
2854 GPR32, RVDR1 G protein-coupled receptor 32 C00002638
9290 GPR55 G protein-coupled receptor 55 C00002638
55507 GPRC5D G protein-coupled receptor, family C, group 5, member D C00002638
284110 GSDMA, GSDM, GSDM1 gasdermin A C00002638
2977 GUCY1A2, GC-SA2, GUC1A2 guanylate cyclase 1, soluble, alpha 2 (EC:4.6.1.2) C00002638
9421 HAND1, Hxt, Thing1, bHLHa27, eHand heart and neural crest derivatives expressed 1 C00002638
3024 HIST1H1A, H1.1, H1A, H1F1, HIST1 histone cluster 1, H1a C00002638
8334 HIST1H2AC, H2A/l, H2AFL, dJ221C16.4 histone cluster 1, H2ac C00002638
3131 HLF hepatic leukemia factor C00002638
3218 HOXB8, HOX2, HOX2D, Hox-2.4 homeobox B8 C00002638
84343 HPS3, SUTAL Hermansky-Pudlak syndrome 3 C00002638
3283 HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) C00002638
27336 HTATSF1, TAT-SF1, TATSF1, dJ196E23.2 HIV-1 Tat specific factor 1 C00002638
3437 IFIT3, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G interferon-induced protein with tetratricopeptide repeats 3 C00002638
9543 IGDCC3, HsT18880, PUNC immunoglobulin superfamily, DCC subclass, member 3 C00002638
51561 IL23A, IL-23, IL-23A, IL23P19, P19, SGRF interleukin 23, alpha subunit p19 C00002638
3563 IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra interleukin 3 receptor, alpha (low affinity) C00002638
3572 IL6ST, CD130, CDW130, GP130, IL-6RB interleukin 6 signal transducer (gp130, oncostatin M receptor) C00002638
9118 INA, NEF5, NF-66, TXBP-1 internexin neuronal intermediate filament protein, alpha C00002638
8821 INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66) C00002638
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00002638
9196 KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 C00002638
79734 KCTD17 potassium channel tetramerization domain containing 17 C00002638
79070 KDELC1, EP58, KDEL1 KDEL (Lys-Asp-Glu-Leu) containing 1 C00002638
55083 KIF26B kinesin family member 26B C00002638
90293 KLHL13, BKLHD2, KIAA1309 kelch-like family member 13 C00002638
8302 KLRC4, NKG2-F, NKG2F killer cell lectin-like receptor subfamily C, member 4 C00002638
197021 LCTL, KLG, KLPH lactase-like C00002638
56891 LGALS14, CLC2, PPL13 lectin, galactoside-binding, soluble, 14 C00002638
79166 LILRP2, CD85m, ILT10, LILRA5 leukocyte immunoglobulin-like receptor pseudogene 2 C00002638
4041 LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2 low density lipoprotein receptor-related protein 5 C00002638
4040 LRP6, ADCAD2 low density lipoprotein receptor-related protein 6 C00002638
64101 LRRC4, NGL-2 leucine rich repeat containing 4 C00002638
80059 LRRTM4 leucine rich repeat transmembrane neuronal 4 C00002638
10349 ABCA10, EST698739 ATP-binding cassette, sub-family A (ABC1), member 10 C00002638
11183 MAP4K5, GCKR, KHS, KHS1, MAPKKKK5 mitogen-activated protein kinase kinase kinase kinase 5 (EC:2.7.11.1) C00002638
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00002638
84515 MCM8, C20orf154, dJ967N21.5 minichromosome maintenance complex component 8 (EC:3.6.4.12) C00002638
4188 MDFI, I-MF, I-mfa MyoD family inhibitor C00002638
4239 MFAP4 microfibrillar-associated protein 4 C00002638
90007 MIDN midnolin C00002638
4288 MKI67, KIA, MIB-1 marker of proliferation Ki-67 C00002638
93380 MMGT1, EMC5, TMEM32 membrane magnesium transporter 1 C00002638
245802 MS4A6E membrane-spanning 4-domains, subfamily A, member 6E C00002638
25902 MTHFD1L, FTHFSDC1, MTC1THFS, dJ292B18.2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3) C00002638
4597 MVD, FP17780, MPD mevalonate (diphospho) decarboxylase (EC:4.1.1.33) C00002638
140469 MYO3B myosin IIIB (EC:2.7.11.1) C00002638
83988 NCALD neurocalcin delta C00002638
257194 NEGR1, DMML2433, IGLON4, KILON, Ntra neuronal growth regulator 1 C00002638
129807 NEU4 sialidase 4 (EC:3.2.1.18) C00002638
85407 NKD1, Naked1 naked cuticle homolog 1 (Drosophila) C00002638
9111 NMI N-myc (and STAT) interactor C00002638
122945 NOXRED1, C14orf148 NADP-dependent oxidoreductase domain containing 1 C00002638
7025 NR2F1, COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1 nuclear receptor subfamily 2, group F, member 1 C00002638
8828 NRP2, NP2, NPN2, PRO2714, VEGF165R2 neuropilin 2 C00002638
4909 NTF4, GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5 neurotrophin 4 C00002638
283298 OLFML1, UNQ564 olfactomedin-like 1 C00002638
23762 OSBP2, HLM, ORP-4, ORP4, OSBPL1, OSBPL4 oxysterol binding protein 2 C00002638
114885 OSBPL11, ORP-11, ORP11, OSBP12, TCCCIA00292 oxysterol binding protein-like 11 C00002638
5013 OTX1 orthodenticle homeobox 1 C00002638
11252 PACSIN2, SDPII protein kinase C and casein kinase substrate in neurons 2 C00002638
8505 PARG, PARG99 poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) C00002638
84108 PCGF6, MBLR, RNF134 polycomb group ring finger 6 C00002638
55251 PCMTD2, C20orf36 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 C00002638
80003 PCNXL2 pecanex-like 2 (Drosophila) C00002638
5174 PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1 PDZ domain containing 1 C00002638
5196 PF4, CXCL4, PF-4, SCYB4 platelet factor 4 C00002638
55276 PGM2 phosphoglucomutase 2 (EC:5.4.2.2 5.4.2.7) C00002638
9091 PIGQ, GPI1, c407A10.1 phosphatidylinositol glycan anchor biosynthesis, class Q (EC:2.4.1.198) C00002638
5300 PIN1, DOD, UBL5 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (EC:5.2.1.8) C00002638
23760 PITPNB, PI-TP-beta, PtdInsTP, VIB1B phosphatidylinositol transfer protein, beta C00002638
5314 PKHD1, ARPKD, FCYT, TIGM1 polycystic kidney and hepatic disease 1 (autosomal recessive) C00002638
5427 POLE2, DPE2 polymerase (DNA directed), epsilon 2, accessory subunit (EC:2.7.7.7) C00002638
51535 PPHLN1, HSPC232 periphilin 1 C00002638
5553 PRG2, BMPG, MBP, MBP1 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) C00002638
5613 PRKX, PKX1 protein kinase, X-linked (EC:2.7.11.1) C00002638
3275 PRMT2, HRMT1L1 protein arginine methyltransferase 2 (EC:2.1.1.125) C00002638
285800 PRR18 proline rich 18 C00002638
5396 PRRX1, AGOTC, PHOX1, PMX1, PRX-1, PRX1 paired related homeobox 1 C00002638
5645 PRSS2, TRY2, TRY8, TRYP2 protease, serine, 2 (trypsin 2) (EC:3.4.21.4) C00002638
5719 PSMD13, HSPC027, Rpn9, S11, p40.5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 C00002638
5709 PSMD3, P58, RPN3, S3, TSTA2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 C00002638
22930 RAB3GAP1, P130, RAB3GAP, RAB3GAP130, WARBM1 RAB3 GTPase activating protein subunit 1 (catalytic) C00002638
51560 RAB6B RAB6B, member RAS oncogene family C00002638
153020 RASGEF1B, GPIG4 RasGEF domain family, member 1B C00002638
10739 RFPL2, RNF79 ret finger protein-like 2 C00002638
10738 RFPL3 ret finger protein-like 3 C00002638
727800 RNF208 ring finger protein 208 C00002638
6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2 ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1) C00002638
54665 RSBN1, ROSBIN, RP11-324J2.1 round spermatid basic protein 1 C00002638
6291 SAA4, C-SAA, CSAA serum amyloid A4, constitutive C00002638
51097 SCCPDH, NET11, RP11-439E19.2 saccharopine dehydrogenase (putative) (EC:1.5.1.9) C00002638
6324 SCN1B, ATFB13, BRGDA5, GEFSP1 sodium channel, voltage-gated, type I, beta subunit C00002638
6385 SDC4, SYND4 syndecan 4 C00002638
6406 SEMG1, CT103, SEMG, SGI, dJ172H20.2 semenogelin I C00002638
5104 SERPINA5, PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 C00002638
3053 SERPIND1, D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 C00002638
23451 SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155 splicing factor 3b, subunit 1, 155kDa C00002638
6425 SFRP5, SARP3 secreted frizzled-related protein 5 C00002638
118980 SFXN2 sideroflexin 2 C00002638
6456 SH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4 SH3-domain GRB2-like 2 C00002638
23309 SIN3B SIN3 transcription regulator family member B C00002638
9058 SLC13A2, NADC1, NaCT, NaDC-1, SDCT1 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 C00002638
51296 SLC15A3, OCTP, PHT2, PTR3 solute carrier family 15 (oligopeptide transporter), member 3 C00002638
6571 SLC18A2, SVAT, SVMT, VAT2, VMAT2 solute carrier family 18 (vesicular monoamine transporter), member 2 C00002638
151295 SLC23A3, E2BP3, SVCT3, Yspl1 solute carrier family 23, member 3 C00002638
83884 SLC25A2, ORC2, ORNT2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 C00002638
10999 SLC27A4, ACSVL4, FATP4, IPS solute carrier family 27 (fatty acid transporter), member 4 (EC:6.2.1.-) C00002638
84889 SLC7A3, ATRC3, CAT-3, CAT3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 C00002638
81796 SLCO5A1, OATP-J, OATP-RP4, OATP5A1, OATPRP4, SLC21A15 solute carrier organic anion transporter family, member 5A1 C00002638
79753 SNIP1, PMRED Smad nuclear interacting protein 1 C00002638
122809 SOCS4, SOCS7 suppressor of cytokine signaling 4 C00002638
221178 SPATA13, ARHGEF29, ASEF2 spermatogenesis associated 13 C00002638
64847 SPATA20, SSP411, Tisp78 spermatogenesis associated 20 C00002638
10558 SPTLC1, HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI serine palmitoyltransferase, long chain base subunit 1 (EC:2.3.1.50) C00002638
9754 STARD8, ARHGAP38, DLC3, STARTGAP3 StAR-related lipid transfer (START) domain containing 8 C00002638
85360 SYDE1, 7h3 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) C00002638
8189 SYMPK, SPK, SYM symplekin C00002638
6886 TAL1, SCL, TCL5, bHLHa17, tal-1 T-cell acute lymphocytic leukemia 1 C00002638
23435 TARDBP, ALS10, TDP-43 TAR DNA binding protein C00002638
6938 TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20 transcription factor 12 C00002638
6947 TCN1, TC-1, TC1, TCI transcobalamin I (vitamin B12 binding protein, R binder family) C00002638
26136 TES, TESS, TESS-2 testis derived transcript (3 LIM domains) C00002638
56156 TEX13B, TGC3B, TSGA5 testis expressed 13B C00002638
7043 TGFB3, ARVD, ARVD1, TGF-beta3 transforming growth factor, beta 3 C00002638
7092 TLL1, ASD6, TLL tolloid-like 1 (EC:3.4.24.-) C00002638
25789 TMEM59L, BSMAP, C19orf4 transmembrane protein 59-like C00002638
54863 TOR4A, C9orf167 torsin family 4, member A C00002638
9697 TRAM2 translocation associated membrane protein 2 C00002638
11181 TREH, TRE, TREA trehalase (brush-border membrane glycoprotein) (EC:3.2.1.28) C00002638
7248 TSC1, LAM, TSC tuberous sclerosis 1 C00002638
9819 TSC22D2, TILZ4a, TILZ4b, TILZ4c TSC22 domain family, member 2 C00002638
128553 TSHZ2, C20orf17, OVC10-2, TSH2, ZABC2, ZNF218 teashirt zinc finger homeobox 2 C00002638
118491 TTC18 tetratricopeptide repeat domain 18 C00002638
55001 TTC22 tetratricopeptide repeat domain 22 C00002638
7289 TULP3, TUBL3 tubby like protein 3 C00002638
51619 UBE2D4, HBUCE1 ubiquitin-conjugating enzyme E2D 4 (putative) (EC:6.3.2.19) C00002638
9040 UBE2M, UBC-RS2, UBC12, hUbc12 ubiquitin-conjugating enzyme E2M (EC:6.3.2.19) C00002638
29979 UBQLN1, DA41, DSK2, PLIC-1, UBQN, XDRP1 ubiquilin 1 C00002638
84101 USP44 ubiquitin specific peptidase 44 (EC:3.4.19.12) C00002638
51118 UTP11L, CGI94 UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) C00002638
157680 VPS13B, CHS1, COH1 vacuolar protein sorting 13 homolog B (yeast) C00002638
23339 VPS39, TLP, VAM6, hVam6p vacuolar protein sorting 39 homolog (S. cerevisiae) C00002638
146177 VWA3A von Willebrand factor A domain containing 3A C00002638
126820 WDR63, DIC3, NYD-SP29, RP11-507C22.2 WD repeat domain 63 C00002638
80326 WNT10A, OODD, SSPS, STHAG4 wingless-type MMTV integration site family, member 10A C00002638
9502 XAGE2, CT12.2, GAGED3, XAGE-2 X antigen family, member 2 C00002638
26137 ZBTB20, DPZF, HOF, ODA-8S, ZNF288 zinc finger and BTB domain containing 20 C00002638
51043 ZBTB7B, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX zinc finger and BTB domain containing 7B C00002638
51201 ZDHHC2, DHHC2, ZNF372 zinc finger, DHHC-type containing 2 (EC:2.3.1.225) C00002638
55888 ZKSCAN7, ZFP, ZNF167, ZNF448, ZNF64, ZSCAN39 zinc finger with KRAB and SCAN domains 7 C00002638
7700 ZNF141, D4S90, PAPA6, pHZ-44 zinc finger protein 141 C00002638
162967 ZNF320, ZFPL zinc finger protein 320 C00002638
117608 ZNF354B, KID2 zinc finger protein 354B C00002638
7592 ZNF41, MRX89 zinc finger protein 41 C00002638
84330 ZNF414, ZFP414 zinc finger protein 414 C00002638
158399 ZNF483, ZKSCAN16, ZSCAN48 zinc finger protein 483 C00002638
162968 ZNF497 zinc finger protein 497 C00002638
93474 ZNF670 zinc finger protein 670 C00002638
347344 ZNF81, HFZ20, MRX45, dJ54B20.6 zinc finger protein 81 C00002638
7783 ZP2, ZPA, Zp-2 zona pellucida glycoprotein 2 (sperm receptor) C00002638
23460 ABCA6, EST155051 ATP-binding cassette, sub-family A (ABC1), member 6 C00000619
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000619
231 AKR1B1, ADR, ALDR1, ALR2, AR aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) C00000619
57016 AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) C00000619
1645 AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) C00000619
8644 AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) C00000619
249 ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) C00000619
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00000619
55114 ARHGAP17, MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH1, RICH1B, WBP15 Rho GTPase activating protein 17 C00000619
10123 ARL4C, ARL7, LAK ADP-ribosylation factor-like 4C C00000619
567 B2M beta-2-microglobulin C00000619
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000619
9774 BCLAF1, BTF, bK211L9.1 BCL2-associated transcription factor 1 C00000619
654 BMP6, VGR, VGR1 bone morphogenetic protein 6 C00000619
699 BUB1, BUB1A, BUB1L, hBUB1 BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) C00000619
57102 C12orf4 chromosome 12 open reading frame 4 C00000619
10203 CALCRL, CGRPR, CRLR calcitonin receptor-like C00000619
847 CAT catalase (EC:1.11.1.6) C00000619
6357 CCL13, CKb10, MCP-4, NCC-1, NCC1, SCYA13, SCYL1 chemokine (C-C motif) ligand 13 C00000619
6363 CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19 chemokine (C-C motif) ligand 19 C00000619
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00000619
6348 CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 chemokine (C-C motif) ligand 3 C00000619
6349 CCL3L1, 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MIP1AP, SCYA3L, SCYA3L1 chemokine (C-C motif) ligand 3-like 1 C00000619
6351 CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 chemokine (C-C motif) ligand 4 C00000619
729230 CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R chemokine (C-C motif) receptor 2 C00000619
1234 CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 chemokine (C-C motif) receptor 5 (gene/pseudogene) C00000619
1236 CCR7, BLR2, CD197, CDw197, CMKBR7, EBI1 chemokine (C-C motif) receptor 7 C00000619
948 CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3 CD36 molecule (thrombospondin receptor) C00000619
942 CD86, B7-2, B7.2, B70, CD28LG2, LAB72 CD86 molecule C00000619
1385 CREB1, CREB cAMP responsive element binding protein 1 C00000619
1390 CREM, CREM-2, ICER, hCREM-2 cAMP responsive element modulator C00000619
1514 CTSL, CATL, CTSL1, MEP cathepsin L (EC:3.4.22.15) C00000619
2919 CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) C00000619
7852 CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM chemokine (C-X-C motif) receptor 4 C00000619
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000619
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000619
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000619
1593 CYP27A1, CP27, CTX, CYP27 cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15) C00000619
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00000619
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) C00000619
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00000619
1736 DKC1, CBF5, DKC, DKCX, NAP57, NOLA4, XAP101 dyskeratosis congenita 1, dyskerin C00000619
9787 DLGAP5, DLG7, HURP discs, large (Drosophila) homolog-associated protein 5 C00000619
1869 E2F1, E2F-1, RBAP1, RBBP3, RBP3 E2F transcription factor 1 C00000619
1870 E2F2, E2F-2 E2F transcription factor 2 C00000619
1871 E2F3, E2F-3 E2F transcription factor 3 C00000619
1874 E2F4, E2F-4 E2F transcription factor 4, p107/p130-binding C00000619
1875 E2F5, E2F-5 E2F transcription factor 5, p130-binding C00000619
1876 E2F6, E2F-6 E2F transcription factor 6 C00000619
1959 EGR2, AT591, CMT1D, CMT4E, KROX20 early growth response 2 C00000619
133418 EMB embigin C00000619
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00000619
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00000619
2162 F13A1, F13A coagulation factor XIII, A1 polypeptide (EC:2.3.2.13) C00000619
26268 FBXO9, FBX9, NY-REN-57, VCIA1, dJ341E18.2 F-box protein 9 C00000619
2213 FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2 Fc fragment of IgG, low affinity IIb, receptor (CD32) C00000619
2235 FECH, EPP, FCE ferrochelatase (EC:4.99.1.1) C00000619
2355 FOSL2, FRA2 FOS-like antigen 2 C00000619
2512 FTL, NBIA3 ferritin, light polypeptide C00000619
2539 G6PD, G6PD1 glucose-6-phosphate dehydrogenase (EC:1.1.1.49) C00000619
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00000619
2730 GCLM, GLCLR glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) C00000619
644076 GLYCAM1 glycosylation dependent cell adhesion molecule 1 (pseudogene) C00000619
2878 GPX3, GPx-P, GSHPx-3, GSHPx-P glutathione peroxidase 3 (plasma) (EC:1.11.1.9) C00000619
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00000619
2936 GSR glutathione reductase (EC:1.8.1.7) C00000619
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00000619
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00000619
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00000619
2994 GYPB, CD235b, GPB, GPB.NY, GYPHe.NY, GpMiIII, HGpMiIII, HGpMiVI, HGpMiX, MNS, PAS-3, SS glycophorin B (MNS blood group) C00000619
54497 HEATR5B HEAT repeat containing 5B C00000619
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00000619
3106 HLA-B, AS, HLAB, SPDA1 major histocompatibility complex, class I, B C00000619
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00000619
220988 HNRNPA3, 2610510D13Rik, D10S102, FBRNP, HNRPA3 heterogeneous nuclear ribonucleoprotein A3 C00000619
3381 IBSP, BNSP, BSP, BSP-II, SP-II integrin-binding sialoprotein C00000619
3422 IDI1, IPP1, IPPI1 isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2) C00000619
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000619
7850 IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB interleukin 1 receptor, type II C00000619
3575 IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA interleukin 7 receptor C00000619
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00000619
26034 IPCEF1, PIP3-E, RP3-402L9.2 interaction protein for cytohesin exchange factors 1 C00000619
3655 ITGA6, CD49f, ITGA6B, VLA-6 integrin, alpha 6 C00000619
3688 ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) C00000619
3741 KCNA5, ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1 potassium voltage-gated channel, shaker-related subfamily, member 5 C00000619
3759 KCNJ2, ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3 potassium inwardly-rectifying channel, subfamily J, member 2 C00000619
9493 KIF23, CHO1, KNSL5, MKLP-1, MKLP1 kinesin family member 23 C00000619
23764 MAFF, U-MAF, hMafF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F C00000619
4097 MAFG, hMAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G C00000619
28985 MCTS1, MCT-1, MCT1 malignant T cell amplified sequence 1 C00000619
4199 ME1, HUMNDME, MES malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) C00000619
4257 MGST1, GST12, MGST, MGST-I microsomal glutathione S-transferase 1 (EC:2.5.1.18) C00000619
51318 MRPL35, L35mt, MRP-L35 mitochondrial ribosomal protein L35 C00000619
58475 MS4A7, 4SPAN2, CD20L4, CFFM4, MS4A8 membrane-spanning 4-domains, subfamily A, member 7 C00000619
4501 MT1X, MT-1l, MT1 metallothionein 1X C00000619
4084 MXD1, BHLHC58, MAD, MAD1 MAX dimerization protein 1 C00000619
154664 ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 C00002638
10135 NAMPT, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN nicotinamide phosphoribosyltransferase (EC:2.4.2.12) C00000619
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00000619
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00000619
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00000619
4927 NUP88 nucleoporin 88kDa C00000619
10606 PAICS, ADE2, ADE2H1, AIRC, PAIS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (EC:6.3.2.6 4.1.1.21) C00000619
5142 PDE4B, DPDE4, PDE4B5, PDEIVB phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) C00000619
5226 PGD, 6PGD phosphogluconate dehydrogenase (EC:1.1.1.44) C00000619
8301 PICALM, CALM, CLTH, LAP phosphatidylinositol binding clathrin assembly protein C00000619
5327 PLAT, T-PA, TPA plasminogen activator, tissue (EC:3.4.21.68) C00000619
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00000619
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00000619
10935 PRDX3, AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III peroxiredoxin 3 (EC:1.11.1.15) C00000619
5733 PTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, PGE2-R prostaglandin E receptor 3 (subtype EP3) C00000619
22949 PTGR1, LTB4DH, PGR1, ZADH3 prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) C00000619
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000619
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00000619
5996 RGS1, 1R20, BL34, IER1, IR20 regulator of G-protein signaling 1 C00000619
6157 RPL27A, L27A ribosomal protein L27a C00000619
50484 RRM2B, MTDPS8A, MTDPS8B, P53R2 ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1) C00000619
6303 SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1 spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) C00000619
6383 SDC2, CD362, HSPG, HSPG1, SYND2 syndecan 2 C00000619
55752 SEPT11 septin 11 C00000619
6504 SLAMF1, CD150, CDw150, SLAM signaling lymphocytic activation molecule family member 1 C00000619
117247 SLC16A10, MCT10, PRO0813, TAT1 solute carrier family 16 (aromatic amino acid transporter), member 10 C00000619
6515 SLC2A3, GLUT3 solute carrier family 2 (facilitated glucose transporter), member 3 C00000619
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00000619
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00000619
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC:1.15.1.1) C00000619
140809 SRXN1, C20orf139, Npn3, SRX, SRX1 sulfiredoxin 1 (EC:1.8.98.2) C00000619
6772 STAT1, CANDF7, ISGF-3, STAT91 signal transducer and activator of transcription 1, 91kDa C00000619
6775 STAT4, SLEB11 signal transducer and activator of transcription 4 C00000619
6777 STAT5B, STAT5 signal transducer and activator of transcription 5B C00000619
7099 TLR4, ARMD10, CD284, TLR-4, TOLL toll-like receptor 4 C00000619
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000619
7128 TNFAIP3, A20, OTUD7C, TNFA1P2 tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) C00000619
7130 TNFAIP6, TSG-6, TSG6 tumor necrosis factor, alpha-induced protein 6 C00000619
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00000619
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00000619
162514 TRPV3, OLMS, VRL3 transient receptor potential cation channel, subfamily V, member 3 C00000619
25828 TXN2, MT-TRX, MTRX, TRX2 thioredoxin 2 C00000619
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00000619
10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2 thioredoxin reductase 2 (EC:1.8.1.9) C00000619
7358 UGDH, GDH, UDP-GlcDH, UDPGDH, UGD UDP-glucose 6-dehydrogenase (EC:1.1.1.22) C00000619
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00000619
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00000619
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00000619
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00000619
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00000619
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00000619
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00000619
7367 UGT2B17, BMND12, UDPGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17) C00000619
7421 VDR, NR1I1 vitamin D (1,25- dihydroxyvitamin D3) receptor C00000619
7709 ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67 zinc finger and BTB domain containing 17 C00000619

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (51)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#612560 Bone mineral density quantitative trait locus 12; bmnd12 O75795
#300615 Brunner syndrome P21397
#114500 Colorectal cancer; crc P84022
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137800 Glioma susceptibility 1; glm1 O75874
P04626
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#603932 Intervertebral disc disease; idd P14780
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#126200 Multiple sclerosis, susceptibility to; ms P08575
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#607276 Resting heart rate, variation in P08588
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (38)

KEGG name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

28 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001943 Breast Neoplasms C00000619
D017449 Dermatitis, Allergic Contact C00000619
D003877 Dermatitis, Contact C00000619
D003875 Drug Eruptions C00000619
D056486 Drug-Induced Liver Injury C00000619
D006331 Heart Diseases C00000619
D006461 Hemolysis C00000619
D006930 Hyperalgesia C00000619
D006967 Hypersensitivity C00000619
D007249 Inflammation C00000619
D008545 Melanoma C00000619
D009361 Neoplasm Invasiveness C00000619
D009362 Neoplasm Metastasis C00000619
D009374 Neoplasms, Experimental C00000619
D009389 Neovascularization, Pathologic C00000619
D009410 Nerve Degeneration C00000619
D010146 Pain C00000619
D010149 Pain, Postoperative C00000619
D010300 Parkinson Disease C00000619
D011833 Radiation Injuries, Experimental C00000619
D012481 Salmonella Infections, Animal C00000619
D012878 Skin Neoplasms C00000619
D013035 Spasm C00000619
D013203 Staphylococcal Infections C00000619
D013274 Stomach Neoplasms C00000619
D013276 Stomach Ulcer C00000619
D014581 Urticaria C00000619
D002583 Uterine Cervical Neoplasms C00000619