Hesperis matronalis
Species
KNApSAcK Entry
| Organism name | Hesperis matronalis |
|---|---|
| Genus | Hesperis |
| Family | Cruciferae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Hesperis matronalis |
|---|---|
| Linked NCBI taxonomy ID | 264418 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Brassicaceae |
|---|---|
| ID | 3700 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (36)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00007586
|
Gluconapin
/ 3-Butyl glucosinolate |
No. 46 | No. 76 |
|
||||
|
C00007864
|
Epiprogoitrin
/ 2(S)-2-Hydroxy-3-butenyl glucosinolate |
No. 46 | No. 76 |
|
||||
|
C00007593
|
Glucoberteroin
/ 5-Methylthiopentylglucosinolate |
No. 46 | No. 76 |
|
||||
|
C00007348
|
Glucohesperin
/ 6-Methylsulfinylhexyl glucosinolate |
No. 46 | No. 76 |
|
||||
|
C00007345
|
Glucoalyssin
/ 5-Methylsulfinylpentyl glucosinolate |
No. 46 | No. 76 |
|
||||
|
C00007344
|
Glucoerucin
/ 4-Methylthiobutyl glucosinolate |
C119493
|
No. 46 | No. 76 |
|
|||
|
C00001468
|
Glucojiabutin
/ Glucocochlearin / sec-Butyl glucosinolate / 1-Methylpropyl glucosinolate |
No. 46 | No. 76 |
|
||||
|
C00001473
|
Glucoiberverin
/ 3-(Methylthio)propyl glucosinolate |
No. 46 | No. 76 |
|
||||
|
C00001486
|
Progoitrin
/ 2(R)-2-Hydroxy 3-butenyl glucosinolate |
C009048
|
No. 46 | No. 76 |
|
|||
|
C00007797
|
Glucomatronalin
/ 3,4-dihydroxybenzyl glucosinolate |
No. 158 | No. 77 |
|
||||
|
C00007350
|
Gluconasturtiin
/ 2-Phenylethylglucosinolate |
C443697
|
No. 158 | No. 77 |
|
|||
|
C00007805
|
Glucosinalbate
/ 4-Hydroxybenzyl glucosinolate |
No. 158 | No. 77 |
|
||||
|
C00022165
|
4,8,12-Trimethyl-1,3E,7E,11-tridecatetraene
/ (E,E)-4,8,12-Trimethyl-1,3,7,11-tridecatetraene |
No. 404 | No. 38 |
|
||||
|
C00000816
|
beta-Pinene
|
CHEMBL501351
|
C010789
|
No. 476 | No. 35 |
|
||
|
C00000805
|
alpha-Pinene
|
CHEMBL442565
|
C005451
|
3 / 3 / 2 | 0 / 1 | No. 476 | No. 35 |
|
|
C00002663
|
2-Phenylethanol
/ Phenethyl alcohol / Phenylethyl alcohol / beta-Phenethyl alcohol |
CHEMBL448500
|
D010626
|
2 / 1 / 1 | No. 885 |
|
||
|
C00029811
|
Benzyl alcohol
/ (Hydroxymethyl)benzene |
CHEMBL720
|
D019905
|
94 / 41 / 36 | 1 / 6 | No. 885 |
|
|
|
C00007674
|
Phenylacetonitrile
|
No. 885 |
|
|||||
|
C00003047
|
Linalool
/ (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol |
CHEMBL25306
CHEMBL235672 |
C018584
|
6 / 8 / 2 | 35 / 4 | No. 958 | No. 34 |
|
|
C00029674
|
alpha-Terpineol
|
CHEMBL447597
CHEMBL449810 |
C016775
|
3 / 16 / 11 | No. 983 | No. 35 |
|
|
|
C00034746
|
Z-Furanoid linalool oxide
|
No. 1005 |
|
|||||
|
C00034496
|
E-Furanoid linalool oxide
|
No. 1005 |
|
|||||
|
C00031258
|
Sabinene
/ 4(10)-Thujene |
CHEMBL452687
|
C035127
|
No. 1343 | No. 35 |
|
||
|
C00029351
|
Z-beta-Ocimene
/ cis-beta-Ocimene / (Z)-beta-Ocimene |
No. 1698 | No. 34 |
|
||||
|
C00000862
|
trans-beta-Ocimene
|
No. 1698 | No. 34 |
|
||||
|
C00034453
|
Benzyl propionate
|
No. 1836 |
|
|||||
|
C00000619
|
Eugenol
|
CHEMBL42710
|
D005054
|
103 / 45 / 36 | 152 / 28 | No. 1852 | No. 6 |
|
|
C00030767
|
Methyl salicylate
|
CHEMBL108545
|
C033069
|
92 / 52 / 46 | 29 / 3 | No. 2169 |
|
|
|
C00000853
|
Myrcene
|
CHEMBL455491
|
C008574
|
3 / 3 / 3 | No. 2285 | No. 34 |
|
|
|
C00019221
|
Benzyl benzoate
|
CHEMBL1239
|
C006723
|
12 / 5 / 8 | 3 / 2 | No. 2308 |
|
|
|
C00034747
|
Z-Pyranoid linalool oxide
|
No. 2943 |
|
|||||
|
C00034600
|
Methyl anthranilate
|
CHEMBL1493986
|
C038892
|
3 / 3 / 3 | No. 4170 |
|
||
|
C00034495
|
Myroxide
/ E-beta-Ocimene epoxide |
No. 4433 |
|
|||||
|
C00011400
|
6-Methyl-5-hepten-2-one
|
CHEMBL46340
|
No. 5297 |
|
||||
|
C00000136
|
1,8-Cineole
|
CHEMBL485259
CHEMBL1397305 |
99 / 57 / 50 | No. 5413 | No. 35 |
|
||
|
C00034452
|
Benzaldehyde
|
CHEMBL15972
|
C032175
|
8 / 7 / 3 | 3 / 1 | No. 6311 |
|
Human Protein / Gene in interactions
130 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000136 C00000619 C00000805 C00029811 C00030767 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000136 C00000619 C00000853 C00029811 C00030767 | 0 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00000136 C00000619 C00029811 C00030767 C00034452 | 1 / 1 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000136 C00000619 C00029811 C00030767 C00034452 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000136 C00000619 C00019221 C00029811 C00030767 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000136 C00000805 C00000853 C00029811 C00030767 | 3 / 2 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000136 C00000619 C00029811 C00030767 | 2 / 2 |
| P08246 | Neutrophil elastase | S1A | C00000136 C00000619 C00029811 C00030767 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000136 C00000619 C00029811 C00030767 | 2 / 2 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000136 C00000619 C00029811 C00030767 | 1 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000136 C00000619 C00029811 C00030767 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000136 C00000619 C00029811 C00030767 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000136 C00000619 C00029811 C00030767 | 0 / 1 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000136 C00000619 C00029811 C00030767 | 0 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000136 C00000619 C00029811 C00030767 | 1 / 8 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000136 C00000619 C00029811 C00030767 | 1 / 1 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000136 C00000619 C00029811 C00030767 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000136 C00000619 C00029811 C00030767 | 1 / 1 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000136 C00000619 C00029811 C00030767 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000136 C00000619 C00029811 C00030767 | 0 / 3 |
| P08311 | Cathepsin G | S1A | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000136 C00000619 C00029811 C00030767 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000136 C00000619 C00029811 C00030767 | 0 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000136 C00000619 C00029811 C00030767 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000136 C00000619 C00029811 C00030767 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000136 C00000619 C00029811 C00030767 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000136 C00000619 C00029811 C00030767 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000136 C00000619 C00029811 C00030767 | 2 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000136 C00000619 C00029811 C00030767 | 1 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000136 C00000619 C00029811 C00030767 | 0 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000619 C00003047 C00029674 | 3 / 0 |
| O75496 | Geminin | Unclassified protein | C00000136 C00000619 C00002663 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000619 C00034452 C00034600 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000136 C00003047 C00019221 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000136 C00029674 C00030767 | 11 / 10 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000619 C00003047 C00029674 | 5 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00019221 C00029811 C00034600 | 0 / 0 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00000619 C00003047 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000619 C00029811 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000136 C00000619 | 3 / 4 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00029811 C00030767 | 2 / 3 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002663 C00019221 | 1 / 1 |
| P10145 | Interleukin-8 | Secreted protein | C00000619 C00034452 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00000853 C00019221 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000619 C00029811 | 0 / 0 |
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | C00000136 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00034452 | 2 / 0 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00034452 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00019221 | 1 / 2 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003047 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000619 | 0 / 0 |
| P40925 | Malate dehydrogenase, cytoplasmic | Enzyme | C00019221 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003047 | 3 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00019221 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00000619 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000136 | 4 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00019221 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000619 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000805 | 0 / 0 |
| P30556 | Type-1 angiotensin II receptor | Angiotensin receptor | C00019221 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00034600 | 3 / 3 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00034452 | 0 / 0 |
| Q7Z2W7 | Transient receptor potential cation channel subfamily M member 8 | Unclassified protein | C00000136 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000619 | 0 / 0 |
| O75795 | UDP-glucuronosyltransferase 2B17 | Enzyme | C00000619 | 1 / 0 |
| P55055 | Oxysterols receptor LXR-beta | NR1H3 | C00000136 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000136 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00034452 | 4 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00019221 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00019221 | 1 / 4 |
191 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000619
C00019221
C00030767
|
| 231 | AKR1B1, ADR, ALDR1, ALR2, AR | aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) |
C00000619
C00029811
C00030767
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00000619
C00003047
C00030767
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00000619
C00003047
C00030767
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00000619
C00030767
|
| 7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00000619
C00030767
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000619
C00030767
|
| 140809 | SRXN1, C20orf139, Npn3, SRX, SRX1 | sulfiredoxin 1 (EC:1.8.98.2) |
C00000619
C00030767
|
| 22949 | PTGR1, LTB4DH, PGR1, ZADH3 | prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) |
C00000619
C00030767
|
| 5226 | PGD, 6PGD | phosphogluconate dehydrogenase (EC:1.1.1.44) |
C00000619
C00030767
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00000619
C00030767
|
| 4199 | ME1, HUMNDME, MES | malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) |
C00000619
C00030767
|
| 4097 | MAFG, hMAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
C00000619
C00030767
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000619
C00030767
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00000619
C00030767
|
| 2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00000619
C00030767
|
| 2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00000619
C00030767
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00000619
C00030767
|
| 2512 | FTL, NBIA3 | ferritin, light polypeptide |
C00000619
C00030767
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00000619
C00030767
|
| 2235 | FECH, EPP, FCE | ferrochelatase (EC:4.99.1.1) |
C00000619
C00030767
|
| 1385 | CREB1, CREB | cAMP responsive element binding protein 1 |
C00000619
C00030767
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000619
C00030767
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000619
C00030767
|
| 57016 | AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI | aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) |
C00000619
C00030767
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000619
C00019221
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000619
C00003047
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000619
C00003047
|
| 4257 | MGST1, GST12, MGST, MGST-I | microsomal glutathione S-transferase 1 (EC:2.5.1.18) |
C00000619
|
| 4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00003047
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00003047
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00003047
|
| 4852 | NPY, PYY4 | neuropeptide Y |
C00003047
|
| 100124292 |
C00003047
|
||
| 3638 | INSIG1, CL-6, CL6 | insulin induced gene 1 |
C00003047
|
| 7295 | TXN, TRDX, TRX, TRX1 | thioredoxin |
C00003047
|
| 7471 | WNT1, BMND16, INT1, OI15 | wingless-type MMTV integration site family, member 1 |
C00003047
|
| 26118 | WSB1, SWIP1, WSB-1 | WD repeat and SOCS box containing 1 |
C00003047
|
| 217 | ALDH2, ALDH-E2, ALDHI, ALDM | aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) |
C00034452
|
| 218 | ALDH3A1, ALDH3, ALDHIII | aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5) |
C00034452
|
| 221 | ALDH3B1, ALDH4, ALDH7 | aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5) |
C00034452
|
| 3398 | ID2, GIG8, ID2A, ID2H, bHLHb26 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
C00003047
|
| 3316 | HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP | heat shock 27kDa protein 2 |
C00003047
|
| 3308 | HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY | heat shock 70kDa protein 4 |
C00003047
|
| 3320 | HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
C00003047
|
| 3297 | HSF1, HSTF1 | heat shock transcription factor 1 |
C00003047
|
| 2010 | EMD, EDMD, LEMD5, STA | emerin |
C00030767
|
| 3156 | HMGCR, LDLCQ3 | 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) |
C00003047
|
| 1647 | GADD45A, DDIT1, GADD45 | growth arrest and DNA-damage-inducible, alpha |
C00003047
|
| 2335 | FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF | fibronectin 1 |
C00003047
|
| 9514 | GAL3ST1, CST | galactose-3-O-sulfotransferase 1 (EC:2.8.2.11) |
C00030767
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00003047
|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00003047
|
| 1509 | CTSD, CLN10, CPSD | cathepsin D (EC:3.4.23.5) |
C00003047
|
| 1447 | CSN2, CASB | casein beta |
C00003047
|
| 1030 | CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
C00003047
|
| 4883 | NPR3, ANP-C, ANPR-C, ANPRC, C5orf23, GUCY2B, NPR-C, NPRC | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) |
C00030767
|
| 1028 | CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2 | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
C00003047
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00003047
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00003047
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00003047
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00003047
|
| 1386 | ATF2, CRE-BP1, CREB2, HB16, TREB7 | activating transcription factor 2 (EC:2.3.1.48) |
C00003047
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00003047
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00030767
|
| 1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00003047
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00019221
|
| 23460 | ABCA6, EST155051 | ATP-binding cassette, sub-family A (ABC1), member 6 |
C00000619
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000619
|
| 249 | ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP | alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) |
C00000619
|
| 367 | AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM | androgen receptor |
C00000619
|
| 55114 | ARHGAP17, MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH1, RICH1B, WBP15 | Rho GTPase activating protein 17 |
C00000619
|
| 10123 | ARL4C, ARL7, LAK | ADP-ribosylation factor-like 4C |
C00000619
|
| 567 | B2M | beta-2-microglobulin |
C00000619
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000619
|
| 9774 | BCLAF1, BTF, bK211L9.1 | BCL2-associated transcription factor 1 |
C00000619
|
| 654 | BMP6, VGR, VGR1 | bone morphogenetic protein 6 |
C00000619
|
| 699 | BUB1, BUB1A, BUB1L, hBUB1 | BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) |
C00000619
|
| 57102 | C12orf4 | chromosome 12 open reading frame 4 |
C00000619
|
| 10203 | CALCRL, CGRPR, CRLR | calcitonin receptor-like |
C00000619
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00000619
|
| 6357 | CCL13, CKb10, MCP-4, NCC-1, NCC1, SCYA13, SCYL1 | chemokine (C-C motif) ligand 13 |
C00000619
|
| 6363 | CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19 | chemokine (C-C motif) ligand 19 |
C00000619
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00000619
|
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00000619
|
| 6349 | CCL3L1, 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MIP1AP, SCYA3L, SCYA3L1 | chemokine (C-C motif) ligand 3-like 1 |
C00000619
|
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 |
C00000619
|
| 729230 | CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R | chemokine (C-C motif) receptor 2 |
C00000619
|
| 1234 | CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
C00000619
|
| 1236 | CCR7, BLR2, CD197, CDw197, CMKBR7, EBI1 | chemokine (C-C motif) receptor 7 |
C00000619
|
| 948 | CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3 | CD36 molecule (thrombospondin receptor) |
C00000619
|
| 942 | CD86, B7-2, B7.2, B70, CD28LG2, LAB72 | CD86 molecule |
C00000619
|
| 1390 | CREM, CREM-2, ICER, hCREM-2 | cAMP responsive element modulator |
C00000619
|
| 1514 | CTSL, CATL, CTSL1, MEP | cathepsin L (EC:3.4.22.15) |
C00000619
|
| 2919 | CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
C00000619
|
| 7852 | CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM | chemokine (C-X-C motif) receptor 4 |
C00000619
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000619
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000619
|
| 1593 | CYP27A1, CP27, CTX, CYP27 | cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15) |
C00000619
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00000619
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00000619
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00000619
|
| 1736 | DKC1, CBF5, DKC, DKCX, NAP57, NOLA4, XAP101 | dyskeratosis congenita 1, dyskerin |
C00000619
|
| 9787 | DLGAP5, DLG7, HURP | discs, large (Drosophila) homolog-associated protein 5 |
C00000619
|
| 1869 | E2F1, E2F-1, RBAP1, RBBP3, RBP3 | E2F transcription factor 1 |
C00000619
|
| 1870 | E2F2, E2F-2 | E2F transcription factor 2 |
C00000619
|
| 1871 | E2F3, E2F-3 | E2F transcription factor 3 |
C00000619
|
| 1874 | E2F4, E2F-4 | E2F transcription factor 4, p107/p130-binding |
C00000619
|
| 1875 | E2F5, E2F-5 | E2F transcription factor 5, p130-binding |
C00000619
|
| 1876 | E2F6, E2F-6 | E2F transcription factor 6 |
C00000619
|
| 1959 | EGR2, AT591, CMT1D, CMT4E, KROX20 | early growth response 2 |
C00000619
|
| 133418 | EMB | embigin |
C00000619
|
| 2162 | F13A1, F13A | coagulation factor XIII, A1 polypeptide (EC:2.3.2.13) |
C00000619
|
| 26268 | FBXO9, FBX9, NY-REN-57, VCIA1, dJ341E18.2 | F-box protein 9 |
C00000619
|
| 2213 | FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2 | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
C00000619
|
| 2355 | FOSL2, FRA2 | FOS-like antigen 2 |
C00000619
|
| 644076 | GLYCAM1 | glycosylation dependent cell adhesion molecule 1 (pseudogene) |
C00000619
|
| 2878 | GPX3, GPx-P, GSHPx-3, GSHPx-P | glutathione peroxidase 3 (plasma) (EC:1.11.1.9) |
C00000619
|
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00000619
|
| 2938 | GSTA1, GST2, GSTA1-1, GTH1 | glutathione S-transferase alpha 1 (EC:2.5.1.18) |
C00000619
|
| 2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00000619
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00000619
|
| 2994 | GYPB, CD235b, GPB, GPB.NY, GYPHe.NY, GpMiIII, HGpMiIII, HGpMiVI, HGpMiX, MNS, PAS-3, SS | glycophorin B (MNS blood group) |
C00000619
|
| 54497 | HEATR5B | HEAT repeat containing 5B |
C00000619
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00000619
|
| 3106 | HLA-B, AS, HLAB, SPDA1 | major histocompatibility complex, class I, B |
C00000619
|
| 220988 | HNRNPA3, 2610510D13Rik, D10S102, FBRNP, HNRPA3 | heterogeneous nuclear ribonucleoprotein A3 |
C00000619
|
| 3381 | IBSP, BNSP, BSP, BSP-II, SP-II | integrin-binding sialoprotein |
C00000619
|
| 3422 | IDI1, IPP1, IPPI1 | isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2) |
C00000619
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00000619
|
| 7850 | IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB | interleukin 1 receptor, type II |
C00000619
|
| 3575 | IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA | interleukin 7 receptor |
C00000619
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000619
|
| 26034 | IPCEF1, PIP3-E, RP3-402L9.2 | interaction protein for cytohesin exchange factors 1 |
C00000619
|
| 3655 | ITGA6, CD49f, ITGA6B, VLA-6 | integrin, alpha 6 |
C00000619
|
| 3688 | ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
C00000619
|
| 3741 | KCNA5, ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1 | potassium voltage-gated channel, shaker-related subfamily, member 5 |
C00000619
|
| 3759 | KCNJ2, ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3 | potassium inwardly-rectifying channel, subfamily J, member 2 |
C00000619
|
| 9493 | KIF23, CHO1, KNSL5, MKLP-1, MKLP1 | kinesin family member 23 |
C00000619
|
| 23764 | MAFF, U-MAF, hMafF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
C00000619
|
| 7975 | MAFK, NFE2U, P18 | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
C00000619
|
| 28985 | MCTS1, MCT-1, MCT1 | malignant T cell amplified sequence 1 |
C00000619
|
| 8850 | KAT2B, CAF, P, P/CAF, PCAF | K(lysine) acetyltransferase 2B (EC:2.3.1.48) |
C00003047
|
| 51318 | MRPL35, L35mt, MRP-L35 | mitochondrial ribosomal protein L35 |
C00000619
|
| 58475 | MS4A7, 4SPAN2, CD20L4, CFFM4, MS4A8 | membrane-spanning 4-domains, subfamily A, member 7 |
C00000619
|
| 4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00000619
|
| 4084 | MXD1, BHLHC58, MAD, MAD1 | MAX dimerization protein 1 |
C00000619
|
| 4602 | MYB, Cmyb, c-myb, c-myb_CDS, efg | v-myb avian myeloblastosis viral oncogene homolog |
C00000619
|
| 10135 | NAMPT, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN | nicotinamide phosphoribosyltransferase (EC:2.4.2.12) |
C00000619
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00000619
|
| 4927 | NUP88 | nucleoporin 88kDa |
C00000619
|
| 10606 | PAICS, ADE2, ADE2H1, AIRC, PAIS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (EC:6.3.2.6 4.1.1.21) |
C00000619
|
| 5142 | PDE4B, DPDE4, PDE4B5, PDEIVB | phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) |
C00000619
|
| 8301 | PICALM, CALM, CLTH, LAP | phosphatidylinositol binding clathrin assembly protein |
C00000619
|
| 5327 | PLAT, T-PA, TPA | plasminogen activator, tissue (EC:3.4.21.68) |
C00000619
|
| 5366 | PMAIP1, APR, NOXA | phorbol-12-myristate-13-acetate-induced protein 1 |
C00000619
|
| 5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma |
C00000619
|
| 10935 | PRDX3, AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III | peroxiredoxin 3 (EC:1.11.1.15) |
C00000619
|
| 5733 | PTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, PGE2-R | prostaglandin E receptor 3 (subtype EP3) |
C00000619
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000619
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00000619
|
| 5996 | RGS1, 1R20, BL34, IER1, IR20 | regulator of G-protein signaling 1 |
C00000619
|
| 6157 | RPL27A, L27A | ribosomal protein L27a |
C00000619
|
| 50484 | RRM2B, MTDPS8A, MTDPS8B, P53R2 | ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1) |
C00000619
|
| 6303 | SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1 | spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) |
C00000619
|
| 6383 | SDC2, CD362, HSPG, HSPG1, SYND2 | syndecan 2 |
C00000619
|
| 55752 | SEPT11 | septin 11 |
C00000619
|
| 6504 | SLAMF1, CD150, CDw150, SLAM | signaling lymphocytic activation molecule family member 1 |
C00000619
|
| 117247 | SLC16A10, MCT10, PRO0813, TAT1 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
C00000619
|
| 6515 | SLC2A3, GLUT3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
C00000619
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00000619
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00000619
|
| 6649 | SOD3, EC-SOD | superoxide dismutase 3, extracellular (EC:1.15.1.1) |
C00000619
|
| 6772 | STAT1, CANDF7, ISGF-3, STAT91 | signal transducer and activator of transcription 1, 91kDa |
C00000619
|
| 6775 | STAT4, SLEB11 | signal transducer and activator of transcription 4 |
C00000619
|
| 6777 | STAT5B, STAT5 | signal transducer and activator of transcription 5B |
C00000619
|
| 7099 | TLR4, ARMD10, CD284, TLR-4, TOLL | toll-like receptor 4 |
C00000619
|
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) |
C00000619
|
| 7130 | TNFAIP6, TSG-6, TSG6 | tumor necrosis factor, alpha-induced protein 6 |
C00000619
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00000619
|
| 162514 | TRPV3, OLMS, VRL3 | transient receptor potential cation channel, subfamily V, member 3 |
C00000619
|
| 25828 | TXN2, MT-TRX, MTRX, TRX2 | thioredoxin 2 |
C00000619
|
| 10587 | TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2 | thioredoxin reductase 2 (EC:1.8.1.9) |
C00000619
|
| 7358 | UGDH, GDH, UDP-GlcDH, UDPGDH, UGD | UDP-glucose 6-dehydrogenase (EC:1.1.1.22) |
C00000619
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000619
|
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) |
C00000619
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00000619
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00000619
|
| 7367 | UGT2B17, BMND12, UDPGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17) |
C00000619
|
| 7421 | VDR, NR1I1 | vitamin D (1,25- dihydroxyvitamin D3) receptor |
C00000619
|
| 7709 | ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67 | zinc finger and BTB domain containing 17 |
C00000619
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (81)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #612560 | Bone mineral density quantitative trait locus 12; bmnd12 |
O75795
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #267430 | Renal tubular dysgenesis; rtd |
P30556
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (66)
| KEGG | name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H00575 | Renal tubular dysgenesis |
P30556
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
42 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D003877 | Dermatitis, Contact |
C00000805
C00019221 C00000619 |
| D017453 | Dermatitis, Irritant |
C00003047
C00029811 |
| D009362 | Neoplasm Metastasis |
C00000619
|
| D006937 | Hypercholesterolemia |
C00003047
|
| D007938 | Leukemia |
C00003047
|
| D009369 | Neoplasms |
C00003047
|
| D012640 | Seizures |
C00034452
|
| D009135 | Muscular Diseases |
C00030767
|
| D009336 | Necrosis |
C00030767
|
| D009395 | Nephritis, Interstitial |
C00030767
|
| D001943 | Breast Neoplasms |
C00000619
|
| D017449 | Dermatitis, Allergic Contact |
C00000619
|
| D003875 | Drug Eruptions |
C00000619
|
| D056486 | Drug-Induced Liver Injury |
C00000619
|
| D006331 | Heart Diseases |
C00000619
|
| D006461 | Hemolysis |
C00000619
|
| D006930 | Hyperalgesia |
C00000619
|
| D006967 | Hypersensitivity |
C00000619
|
| D007249 | Inflammation |
C00000619
|
| D008545 | Melanoma |
C00000619
|
| D009361 | Neoplasm Invasiveness |
C00000619
|
| D012532 | Scabies |
C00019221
|
| D009374 | Neoplasms, Experimental |
C00000619
|
| D009389 | Neovascularization, Pathologic |
C00000619
|
| D009410 | Nerve Degeneration |
C00000619
|
| D010146 | Pain |
C00000619
|
| D010149 | Pain, Postoperative |
C00000619
|
| D010300 | Parkinson Disease |
C00000619
|
| D011833 | Radiation Injuries, Experimental |
C00000619
|
| D012481 | Salmonella Infections, Animal |
C00000619
|
| D012878 | Skin Neoplasms |
C00000619
|
| D013035 | Spasm |
C00000619
|
| D013203 | Staphylococcal Infections |
C00000619
|
| D013274 | Stomach Neoplasms |
C00000619
|
| D013276 | Stomach Ulcer |
C00000619
|
| D014581 | Urticaria |
C00000619
|
| D002583 | Uterine Cervical Neoplasms |
C00000619
|
| D001145 | Arrhythmias, Cardiac |
C00029811
|
| D004342 | Drug Hypersensitivity |
C00029811
|
| D007022 | Hypotension |
C00029811
|
| D010264 | Paraplegia |
C00029811
|
| D011843 | Radiculopathy |
C00029811
|