Lippia javanica

• Index
• Plant Species
• Natural Activity
• Metabolite list (20)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Lippia javanica
Genus	Lippia
Family	Verbenaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Lippia javanica
Linked NCBI taxonomy ID	925357
Linked level	species

Family

Family in NCBI taxonomy	Verbenaceae
ID	21910

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Natural Activity

List (11)

Species	Activity
Lippia javanica (Burm. F.) Spreng.	Analgesic
Lippia javanica (Burm. F.) Spreng.	Antiaggregant
Lippia javanica (Burm. F.) Spreng.	Antihistaminic
Lippia javanica (Burm. F.) Spreng.	Antiseptic
Lippia javanica (Burm. F.) Spreng.	Crocodile Repellent
Lippia javanica (Burm. F.) Spreng.	Decongestant
Lippia javanica (Burm. F.) Spreng.	Hemostat
Lippia javanica (Burm. F.) Spreng.	Icterogenic
Lippia javanica (Burm. F.) Spreng.	Insectifuge
Lippia javanica (Burm. F.) Spreng.	phototoxic
Lippia javanica (Burm. F.) Spreng.	Vermifuge

Metabolite list (20)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00029977	cis-Verbenol					No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00012474	Isocaryophyllene / cis-Caryophyllene / (Z)-Caryophyllene / gamma-Caryophyllen / (-)-Isocaryophyllene	CHEMBL445740 CHEMBL448700		2 / 3 / 7		No. 478	No. 38
C00012483	Betula pubescens / Caryophyllene oxide / trans-Caryophyllene oxide / beta-Caryophyllene epoxide / (-)-Epoxydihydrocaryophyllene / 6,7-Epoxy-3(15)-caryophyllene / (-)-beta-Caryophyllene epoxide / 4beta,5alpha-Epoxycaryophyllene / Caryophyllene 4beta,5alpha-epoxide	CHEMBL399036 CHEMBL508894 CHEMBL479134 CHEMBL1513806 CHEMBL1553274		3 / 1 / 3		No. 500
C00021230	Aromadendrene / (+)-Aromadendrene / (+)-Aromadendr-7(15)-ene	CHEMBL509805 CHEMBL596664				No. 640
C00003028	Borneol / (+/-)-Borneol	CHEMBL296404 CHEMBL486208 CHEMBL1097205 CHEMBL1968981		8 / 5 / 1		No. 649	No. 35
C00000823	Limonene	CHEMBL15799 CHEMBL449062	C008281	7 / 21 / 48	6 / 6	No. 848	No. 35
C00003047	Linalool / (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol	CHEMBL25306 CHEMBL235672	C018584	6 / 8 / 2	35 / 4	No. 958	No. 34
C00029674	alpha-Terpineol	CHEMBL447597 CHEMBL449810	C016775	3 / 16 / 11		No. 983	No. 35
C00035062	Carvone	CHEMBL15676 CHEMBL501949	C006923	8 / 9 / 9	5 / 2	No. 1740	No. 35
C00000619	Eugenol	CHEMBL42710	D005054	103 / 45 / 36	152 / 28	No. 1852	No. 6
C00000819	(+)-Camphor	CHEMBL504760 CHEMBL1316134	D002164	99 / 56 / 51	5 / 3	No. 1921	No. 35
C00035823	Citronellal	CHEMBL1081721	C108217	2 / 0 / 3	0 / 2	No. 1948	No. 34
C00029544	4-Terpineol / Terpin-4-ol / Terpineol-4 / Terpinen-4-ol	CHEMBL507795	C034019	1 / 3 / 0		No. 2215
C00003067	Verbenone / (R)-(+)-Verbenone	CHEMBL1409937				No. 2232	No. 35
C00003029	Camphene	CHEMBL506889 CHEMBL510535	C019286			No. 2460	No. 35
C00003060	alpha-Terpinene					No. 2468	No. 35
C00000136	1,8-Cineole	CHEMBL485259 CHEMBL1397305		99 / 57 / 50		No. 5413	No. 35
C00035852	Limonene oxide		C028940			No. 6974	No. 35

Human Protein / Gene in interactions

128 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000619 C00003028 C00003047 C00029544 C00029674	3 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000136 C00000619 C00000819 C00000823 C00035823	0 / 3
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000136 C00000619 C00000819 C00012483	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000136 C00000619 C00000819 C00012483	0 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00000136 C00000619 C00000805 C00000819	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000136 C00000619 C00000819 C00012483	0 / 1
P02545	Prelamin-A/C	Unclassified protein	C00000136 C00000819 C00000823 C00029674	11 / 10
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000619 C00003028 C00003047 C00029674	5 / 1
P25103	Substance-P receptor	Neurokinin receptor	C00000136 C00000619 C00000819	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00000819	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000136 C00000619 C00000819	2 / 2
P08246	Neutrophil elastase	S1A	C00000136 C00000619 C00000819	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00000136 C00000619 C00000819	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000136 C00000619 C00000819	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000136 C00000619 C00000819	0 / 0
P29466	Caspase-1	C14	C00000136 C00000619 C00000819	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000136 C00000619 C00000819	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000136 C00000619 C00000819	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000136 C00000619 C00000819	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000136 C00000619 C00000819	2 / 2
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000136 C00000619 C00000819	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00000819	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000823 C00003047 C00035062	3 / 1
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000136 C00000619 C00000819	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000136 C00000619 C00000819	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00000819	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000136 C00000619 C00000819	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00000136 C00000619 C00000819	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000136 C00000619 C00000819	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000136 C00000619 C00000819	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000136 C00000619 C00000819	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00000819	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000136 C00000619 C00000819	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000136 C00000619 C00000819	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000136 C00000619 C00000819	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000136 C00000619 C00000819	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000136 C00000619 C00000819	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000136 C00000619 C00000819	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000136 C00000619 C00000819	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00000819	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000136 C00000619 C00000819	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000136 C00000619 C00000819	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000136 C00000619 C00000819	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000136 C00000619 C00000819	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000136 C00000619 C00000819	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000136 C00000619 C00000819	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000136 C00000619 C00000819	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000136 C00000619 C00000819	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000136 C00000619 C00000819	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000619 C00000819 C00035062	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000136 C00000619 C00000819	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000136 C00000619 C00000819	0 / 0
O00255	Menin	Unclassified protein	C00000819 C00012474 C00035062	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000819 C00012474 C00035062	1 / 2
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000136 C00000619 C00000819	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00000819	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00000819	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000136 C00000619 C00000819	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00000819	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000136 C00000619 C00000819	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000136 C00000619 C00000819	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000136 C00000619 C00000819	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000136 C00000619 C00000819	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000136 C00000619 C00000819	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000136 C00000619 C00000819	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000136 C00000619 C00000819	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000136 C00000619 C00000819	0 / 0
P08311	Cathepsin G	S1A	C00000136 C00000619 C00000819	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000136 C00000619 C00000819	1 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000136 C00000619 C00000819	0 / 0
P03956	Interstitial collagenase	M10A	C00000136 C00000619 C00000819	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000136 C00000619 C00000819	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000136 C00000619 C00000819	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000136 C00000619 C00000819	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000136 C00000619 C00000819	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000136 C00000619 C00000819	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000136 C00000619 C00000819	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000136 C00000619 C00000819	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000136 C00000619 C00000819	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000136 C00000619 C00000819	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000136 C00000619 C00000819	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000136 C00000619 C00000819	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000136 C00000619 C00000819	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000136 C00000619 C00000819	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000136 C00000619 C00000819	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000136 C00000619 C00000819	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000136 C00000619 C00000819	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000136 C00000619 C00000819	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000136 C00000619 C00000819	1 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000136 C00000619 C00000819	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000136 C00000619 C00000819	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000136 C00000619 C00000819	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000136 C00000619 C00000819	1 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00000819 C00035062	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00000819	1 / 0
P03372	Estrogen receptor	NR3A1	C00000136 C00000619 C00000819	1 / 1
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00000619 C00003028 C00003047	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000136 C00000619 C00000819	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000619 C00003028	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000136 C00000805	3 / 2
P10275	Androgen receptor	NR3C4	C00000136 C00000619	3 / 4
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000823 C00035062	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000619 C00003028	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000619 C00003028	0 / 0
O75496	Geminin	Unclassified protein	C00000136 C00000619	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000136 C00003047	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000619 C00003028	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000136 C00000819	4 / 3
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003047	0 / 0
P10145	Interleukin-8	Secreted protein	C00000619	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00035823	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00000619	0 / 0
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00003028	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00000819	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00000136	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00000136	0 / 0
O75762	Transient receptor potential cation channel subfamily A member 1	Unclassified protein	C00000819	1 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00000823	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000819	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000823	0 / 0
Q7Z2W7	Transient receptor potential cation channel subfamily M member 8	Unclassified protein	C00000136	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00035062	2 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000619	0 / 0
Q8NET8	Transient receptor potential cation channel subfamily V member 3	Unclassified protein	C00000819	1 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000136	0 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00000619	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00000823	7 / 37
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00035062	1 / 1

190 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000619 C00000823 C00003047
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000619 C00000823 C00003047
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000619 C00000823
162514	TRPV3, OLMS, VRL3	transient receptor potential cation channel, subfamily V, member 3	C00000619 C00000819
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00000619 C00003047
2566	GABRG2, CAE2, ECA2, GEFSP3	gamma-aminobutyric acid (GABA) A receptor, gamma 2	C00000819 C00035062
2561	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	C00000819 C00035062
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000619 C00000823
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00000619 C00003047
4852	NPY, PYY4	neuropeptide Y	C00000823 C00003047
2554	GABRA1, ECA4, EJM, EJM5	gamma-aminobutyric acid (GABA) A receptor, alpha 1	C00000819 C00035062
4927	NUP88	nucleoporin 88kDa	C00000619
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00003047
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00003047
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003047
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003047
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003047
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003047
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003047
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003047
1447	CSN2, CASB	casein beta	C00003047
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00003047
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00003047
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003047
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003047
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003047
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00000823
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003047
3297	HSF1, HSTF1	heat shock transcription factor 1	C00003047
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00003047
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00003047
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00003047
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00003047
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00003047
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003047
8850	KAT2B, CAF, P, P/CAF, PCAF	K(lysine) acetyltransferase 2B (EC:2.3.1.48)	C00003047
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00003047
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00003047
388	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6	ras homolog family member B	C00035062
100124292			C00003047
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00003047
7471	WNT1, BMND16, INT1, OI15	wingless-type MMTV integration site family, member 1	C00003047
26118	WSB1, SWIP1, WSB-1	WD repeat and SOCS box containing 1	C00003047
1555	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450	cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1)	C00000819
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00035062
23460	ABCA6, EST155051	ATP-binding cassette, sub-family A (ABC1), member 6	C00000619
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000619
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000619
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00000619
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000619
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000619
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00000619
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00000619
55114	ARHGAP17, MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH1, RICH1B, WBP15	Rho GTPase activating protein 17	C00000619
10123	ARL4C, ARL7, LAK	ADP-ribosylation factor-like 4C	C00000619
567	B2M	beta-2-microglobulin	C00000619
9774	BCLAF1, BTF, bK211L9.1	BCL2-associated transcription factor 1	C00000619
654	BMP6, VGR, VGR1	bone morphogenetic protein 6	C00000619
699	BUB1, BUB1A, BUB1L, hBUB1	BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1)	C00000619
57102	C12orf4	chromosome 12 open reading frame 4	C00000619
10203	CALCRL, CGRPR, CRLR	calcitonin receptor-like	C00000619
847	CAT	catalase (EC:1.11.1.6)	C00000619
6357	CCL13, CKb10, MCP-4, NCC-1, NCC1, SCYA13, SCYL1	chemokine (C-C motif) ligand 13	C00000619
6363	CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19	chemokine (C-C motif) ligand 19	C00000619
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00000619
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00000619
6349	CCL3L1, 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MIP1AP, SCYA3L, SCYA3L1	chemokine (C-C motif) ligand 3-like 1	C00000619
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00000619
729230	CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R	chemokine (C-C motif) receptor 2	C00000619
1234	CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22	chemokine (C-C motif) receptor 5 (gene/pseudogene)	C00000619
1236	CCR7, BLR2, CD197, CDw197, CMKBR7, EBI1	chemokine (C-C motif) receptor 7	C00000619
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00000619
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00000619
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00000619
1390	CREM, CREM-2, ICER, hCREM-2	cAMP responsive element modulator	C00000619
1514	CTSL, CATL, CTSL1, MEP	cathepsin L (EC:3.4.22.15)	C00000619
2919	CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	C00000619
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00000619
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000619
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000619
1593	CYP27A1, CP27, CTX, CYP27	cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15)	C00000619
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000619
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00000619
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00000619
1736	DKC1, CBF5, DKC, DKCX, NAP57, NOLA4, XAP101	dyskeratosis congenita 1, dyskerin	C00000619
9787	DLGAP5, DLG7, HURP	discs, large (Drosophila) homolog-associated protein 5	C00000619
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00000619
1870	E2F2, E2F-2	E2F transcription factor 2	C00000619
1871	E2F3, E2F-3	E2F transcription factor 3	C00000619
1874	E2F4, E2F-4	E2F transcription factor 4, p107/p130-binding	C00000619
1875	E2F5, E2F-5	E2F transcription factor 5, p130-binding	C00000619
1876	E2F6, E2F-6	E2F transcription factor 6	C00000619
1959	EGR2, AT591, CMT1D, CMT4E, KROX20	early growth response 2	C00000619
133418	EMB	embigin	C00000619
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000619
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000619
2162	F13A1, F13A	coagulation factor XIII, A1 polypeptide (EC:2.3.2.13)	C00000619
26268	FBXO9, FBX9, NY-REN-57, VCIA1, dJ341E18.2	F-box protein 9	C00000619
2213	FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2	Fc fragment of IgG, low affinity IIb, receptor (CD32)	C00000619
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00000619
2355	FOSL2, FRA2	FOS-like antigen 2	C00000619
2512	FTL, NBIA3	ferritin, light polypeptide	C00000619
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00000619
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00000619
644076	GLYCAM1	glycosylation dependent cell adhesion molecule 1 (pseudogene)	C00000619
2878	GPX3, GPx-P, GSHPx-3, GSHPx-P	glutathione peroxidase 3 (plasma) (EC:1.11.1.9)	C00000619
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00000619
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00000619
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00000619
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00000619
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000619
2994	GYPB, CD235b, GPB, GPB.NY, GYPHe.NY, GpMiIII, HGpMiIII, HGpMiVI, HGpMiX, MNS, PAS-3, SS	glycophorin B (MNS blood group)	C00000619
54497	HEATR5B	HEAT repeat containing 5B	C00000619
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00000619
3106	HLA-B, AS, HLAB, SPDA1	major histocompatibility complex, class I, B	C00000619
220988	HNRNPA3, 2610510D13Rik, D10S102, FBRNP, HNRPA3	heterogeneous nuclear ribonucleoprotein A3	C00000619
3381	IBSP, BNSP, BSP, BSP-II, SP-II	integrin-binding sialoprotein	C00000619
3422	IDI1, IPP1, IPPI1	isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2)	C00000619
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000619
7850	IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB	interleukin 1 receptor, type II	C00000619
3575	IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA	interleukin 7 receptor	C00000619
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000619
26034	IPCEF1, PIP3-E, RP3-402L9.2	interaction protein for cytohesin exchange factors 1	C00000619
3655	ITGA6, CD49f, ITGA6B, VLA-6	integrin, alpha 6	C00000619
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00000619
3741	KCNA5, ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1	potassium voltage-gated channel, shaker-related subfamily, member 5	C00000619
3759	KCNJ2, ATFB9, HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3	potassium inwardly-rectifying channel, subfamily J, member 2	C00000619
9493	KIF23, CHO1, KNSL5, MKLP-1, MKLP1	kinesin family member 23	C00000619
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00000619
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00000619
7975	MAFK, NFE2U, P18	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	C00000619
28985	MCTS1, MCT-1, MCT1	malignant T cell amplified sequence 1	C00000619
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00000619
4257	MGST1, GST12, MGST, MGST-I	microsomal glutathione S-transferase 1 (EC:2.5.1.18)	C00000619
51318	MRPL35, L35mt, MRP-L35	mitochondrial ribosomal protein L35	C00000619
58475	MS4A7, 4SPAN2, CD20L4, CFFM4, MS4A8	membrane-spanning 4-domains, subfamily A, member 7	C00000619
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00000619
4084	MXD1, BHLHC58, MAD, MAD1	MAX dimerization protein 1	C00000619
4602	MYB, Cmyb, c-myb, c-myb_CDS, efg	v-myb avian myeloblastosis viral oncogene homolog	C00000619
10135	NAMPT, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN	nicotinamide phosphoribosyltransferase (EC:2.4.2.12)	C00000619
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000619
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000619
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00003047
10606	PAICS, ADE2, ADE2H1, AIRC, PAIS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (EC:6.3.2.6 4.1.1.21)	C00000619
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00000619
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00000619
8301	PICALM, CALM, CLTH, LAP	phosphatidylinositol binding clathrin assembly protein	C00000619
5327	PLAT, T-PA, TPA	plasminogen activator, tissue (EC:3.4.21.68)	C00000619
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00000619
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00000619
10935	PRDX3, AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III	peroxiredoxin 3 (EC:1.11.1.15)	C00000619
5733	PTGER3, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, PGE2-R	prostaglandin E receptor 3 (subtype EP3)	C00000619
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00000619
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000619
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00000619
5996	RGS1, 1R20, BL34, IER1, IR20	regulator of G-protein signaling 1	C00000619
6157	RPL27A, L27A	ribosomal protein L27a	C00000619
50484	RRM2B, MTDPS8A, MTDPS8B, P53R2	ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1)	C00000619
6303	SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1	spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57)	C00000619
6383	SDC2, CD362, HSPG, HSPG1, SYND2	syndecan 2	C00000619
55752	SEPT11	septin 11	C00000619
6504	SLAMF1, CD150, CDw150, SLAM	signaling lymphocytic activation molecule family member 1	C00000619
117247	SLC16A10, MCT10, PRO0813, TAT1	solute carrier family 16 (aromatic amino acid transporter), member 10	C00000619
6515	SLC2A3, GLUT3	solute carrier family 2 (facilitated glucose transporter), member 3	C00000619
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00000619
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00000619
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00000619
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00000619
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00000619
6775	STAT4, SLEB11	signal transducer and activator of transcription 4	C00000619
6777	STAT5B, STAT5	signal transducer and activator of transcription 5B	C00000619
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00000619
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000619
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00000619
7130	TNFAIP6, TSG-6, TSG6	tumor necrosis factor, alpha-induced protein 6	C00000619
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00000619
25828	TXN2, MT-TRX, MTRX, TRX2	thioredoxin 2	C00000619
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000619
10587	TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2	thioredoxin reductase 2 (EC:1.8.1.9)	C00000619
7358	UGDH, GDH, UDP-GlcDH, UDPGDH, UGD	UDP-glucose 6-dehydrogenase (EC:1.1.1.22)	C00000619
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000619
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000619
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00000619
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000619
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000619
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000619
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000619
7367	UGT2B17, BMND12, UDPGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17)	C00000619
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00000619
7709	ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67	zinc finger and BTB domain containing 17	C00000619

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